Radiation combined with antiangiogenic and antivascular agents

Seminars in Radiation Oncology

Volumn 16, Issue 1, 2006, Pages 45-50

  O'Reilly, Michael S ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DIMETHYL 5 (2 OXO 1H INDOL 3 YLMETHYLENE) 3 PYRROLEPROPIONIC ACID; ALPHA INTERFERON; ANGIOGENESIS INHIBITOR; CELECOXIB; CETUXIMAB; COMBRETASTATIN A4; CYCLOOXYGENASE 2 INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; FUMAGILLOL CHLOROACETYLCARBAMATE; GEFITINIB; METALLOPROTEINASE INHIBITOR; MINOCYCLINE; N ACETYLCOLCHINOL PHOSPHATE; PROTEIN TYROSINE KINASE INHIBITOR; SEMAXANIB; SU 11657; SUNITINIB; UNCLASSIFIED DRUG; VANDETANIB; VASCULAR TARGETING AGENT; VASCULOTROPIN INHIBITOR; VATALANIB;

ANGIOGENESIS; ANTINEOPLASTIC ACTIVITY; BREAST CARCINOMA; CANCER; CANCER RADIOTHERAPY; DRUG ACTIVITY; DRUG EFFICACY; GIANT CELL TUMOR; HEMANGIOMA; HUMAN; LUNG CANCER; MONOTHERAPY; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; TREATMENT OUTCOME; TUMOR VASCULARIZATION;

EID: 29244454573     PISSN: 10534296     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semradonc.2005.08.006     Document Type: Article

References (55)

1. M.S. O'Reilly Antiangiogenesis basic principles S.A. Rosenberg Principles and Practice of the Biologic Therapy of Cancer Third edition 2000 Lippincott Williams & Wilkins Philadelphia 827 843
2. R.K. Jain Normalizing tumor vasculature with anti-angiogenic therapy A new paradigm for combination therapy Nat Med 7 2001 987 989
3. M.A. Konerding, W. Malkusch, B. Klapthor Evidence for characteristic vascular patterns in solid tumours Quantitative studies using corrosion casts Br J Cancer 80 1999 724 732
4. H.F. Dvorak Tumors Wounds that do not heal N Engl J Med 315 1986 1650 1659
5. J. Rak, J. Filmus, R.S. Kerbel Reciprocal paracrine interactions between tumour cells and endothelial cells The 'angiogenesis progression' hypothesis Eur J Cancer 32A 1996 2438 2450
6. J. Folkman Tumor angiogenesis and tissue factor Nat Med 2 1996 167 168
7. H. Hurwitz Integrating the anti-VEGF-A humanized monoclonal antibody bevacizumab with chemotherapy in advanced colorectal cancer Clin Colorectal Cancer 4 suppl 2 2004 S62 S68
8. X. Huang, G. Molema, S. King Tumor infarction in mice by antibody-directed targeting of tissue factor to tumor vasculature Science 275 1997 547 550
9. P.E. Thorpe Vascular targeting agents as cancer therapeutics Clin Cancer Res 10 2004 415 427
10. W. Arap, R. Pasqualini, E. Ruoslahti Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model Science 279 1998 377 380
11. M.R. Horsman, R. Murata Vascular targeting effects of ZD6126 in a C3H mouse mammary carcinoma and the enhancement of radiation response Int J Radiat Oncol Biol Phys 57 2003 1047 1055
12. D.W. Siemann, A.M. Rojiani Enhancement of radiation therapy by the novel vascular targeting agent ZD6126 Int J Radiat Oncol Biol Phys 53 2002 164 171
13. D. Raben, C. Bianco, V. Damiano Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model Mol Cancer Ther 3 2004 977 983
14. P.R. Wachsberger, R. Burd, N. Marero Effect of the tumor vascular-damaging agent, ZD6126, on the radioresponse of U87 glioblastoma Clin Cancer Res 11 2005 835 842
15. M. Garcia-Barros, F. Paris, C. Cordon-Cardo Tumor response to radiotherapy regulated by endothelial cell apoptosis Science 300 2003 1155 1159
16. M.S. O'Reilly, L. Holmgren, C. Chen Angiostatin induces and sustains dormancy of human primary tumors in mice Nat Med 2 1996 689 692
17. R.A.B. Ezekowitz, J.B. Mulliken, J. Folkman Interferon alfa-2a therapy for life-threatening hemangiomas of infancy N. Engl J Med 326 1992 1456 1463
18. L.B. Kaban, J.B. Mulliken, R.A. Ezekowitz Antiangiogenic therapy of a recurrent giant cell tumor of the mandible with interferon alfa-2a Pediatrics 103 1999 1145 1149
19. T. Boehm, J. Folkman, T. Browder Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance Nature 390 1997 404 407
20. B. Hobson, J. Denekamp Endothelial proliferation in tumors and normal tissues Continuous labeling studies Br J Cancer 49 1984 405 413
21. D.H. Gorski, M.A. Beckett, N.T. Jaskowiak Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation Cancer Res 59 1999 3374 3378
22. H. Kaplan, E. Murphy The effect of local roentgen irradiation on the biological behavior of a transplantable mouse carcinoma. Increased frequency of pulmonary metastasis J Natl Cancer Inst 9 1949 407 413
23. H. Suit, R. Sedlacek, E. Gillette Examination for a correlation between probabilities of development of distant metastasis and local recurrence Radiology 95 1970 189 194
24. J. Hast, I.B. Schiffer, B. Neugebauer Angiogenesis and fibroblast proliferation precede formation of recurrent tumors after radiation therapy in nude mice Anticancer Res 22 2002 677 688
25. K. Camphausen, M.A. Moses, W.D. Beecken Radiation therapy to a primary tumor accelerates metastatic growth in mice Cancer Res 61 2001 2207 2211
26. L. Milas Tumor bed effect in murine tumors Relationship to tumor take and tumor macrophage content Radiat Res 123 1990 232 236
27. A.C. Hartford, T. Gohongi, D. Fukumura Irradiation of a primary tumor, unlike surgical removal, enhances angiogenesis suppression at a distal site Potential role of host-tumor interaction Cancer Res 60 2000 2128 2131
28. B.A. Teicher, N. Dupuis, T. Kusomoto Antiangiogenic agents can increase tumor oxygenation and response to radiation therapy Radiat Oncol Invest 2 1995 269 276
29. R. Murata, Y. Nishimura, M. Hiraoka An antiangiogenic agent (TNP-470) inhibited reoxygenation during fractionated radiotherapy of murine mammary carcinoma Int J Radiat Oncol Biol Phys 37 1997 1107 1113
30. E.L. Lund, L. Bastholm, P.E. Kristjansen Therapeutic synergy of TNP-470 and ionizing radiation Effects on tumor growth, vessel morphology, and angiogenesis in human glioblastoma multiforme xenografts Clin Cancer Res 6 2000 971 978
31. H.J. Mauceri, N.N. Hanna, M.A. Beckett Combined effects of angiostatin and ionizing radiation in antitumour therapy Nature 394 1998 287 291
32. L. Milas, K. Mason, N. Hunter In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody Clin Cancer Res 6 2000 701 708
33. Z. Liao, R. Komaki, L. Milas A phase I clinical trial of thoracic radiotherapy and concurrent celecoxib for patients with unfavorable performance status inoperable/unresectable non-small cell lung cancer Clin Cancer Res 11 2005 3342 3348
34. C.H. Baker, M.F. McCarty, R. Tsan Phenotypic diversity of organ-specific endothelial cells Proc Am Assoc Cancer Res 42 2001 2186 (abstr)
35. D. Raben, B. Helfrich, D.C. Chan The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer Clin Cancer Res 11 2005 795 805
36. S.M. Huang, P.M. Harari Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis Clin Cancer Res 6 2000 2166 2174
37. S.M. Huang, J. Li, E.A. Armstrong Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa) Cancer Res 62 2002 4300 4306
38. P. Chinnaiyan, S. Huang, G. Vallabhaneni Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva) Cancer Res 65 2005 3328 3335
39. E. Brogi, T. Wu, A. Namiki Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only Circulation 90 1994 649 652
40. H. Uehara, S.J. Kim, T. Karashima Blockade of the PDGF-R signaling by STI571 inhibits angiogenesis and growth of human prostate cancer cells in the bone of nude mice Proc Am Assoc Cancer Res 42 2001 2192 (abstr)
41. A.J. Schueneman, E. Himmelfarb, L. Geng SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models Cancer Res 63 2003 4009 4016
42. N. Hansen-Algenstaedt, B.R. Stoll, T.P. Padera Tumor oxygenation in hormone-dependent tumors during vascular endothelial growth factor receptor-2 blockade, hormone ablation, and chemotherapy Cancer Res 60 2000 4556 4560
43. C.G. Lee, M. Heijn, E. di Tomaso Anti-Vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions Cancer Res 60 2000 5565 5570
44. C. Hess, V. Vuong, I. Hegyi Effect of VEGF receptor inhibitor PTK787/ZK222584 [correction of ZK222548] combined with ionizing radiation on endothelial cells and tumour growth Br J Cancer 85 2001 2010 2016
45. L. Geng, E. Donnelly, G. McMahon Inhibition of vascular endothelial growth factor receptor signaling leads to reversal of tumor resistance to radiotherapy Cancer Res 61 2001 2413 2419
46. S. Kozin, Y. Boucher, D.J. Hicklin Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts Cancer Res 61 2001 39 44
47. J. Schuuring, J. Bussink, H.J.J. Bernsen Irradiation combined with SU5416 Microvascular changes and growth delay in a human xenograft glioblastoma tumor line Int J Radiat Oncol Biol Phys 61 2005 529 534
48. D.H. Gorski, H.J. Mauceri, R.M. Salloum Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin Cancer Res 58 1998 5686 5689
49. S. Ning, D. Laird, J.M. Cherrington The antiangiogenic agents SU5416 and SU6668 increase the antitumor effects of fractionated irradiation Radiat Res 157 2002 45 51
50. K.J. Williams, B.A. Telfer, S. Brave ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy Schedule-dependent enhancement of antitumor activity Clin Cancer Res 10 2004 8587 8593
51. D. Zips, F. Hessel, M. Krause Impact of adjuvant inhibition of vascular endothelial growth factor receptor tyrosine kinases on tumor growth delay and local tumor control after fractionated irradiation in human squamous cell carcinomas in nude mice Int J Radiat Oncol Biol Phys 61 2005 908 914
52. F. Winkler, S.V. Kozin, R.T. Tong Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation Role of oxygenation, angiopoietin-1, and matrix metalloproteinases Cancer Cell 6 2004 553 563
53. B.A. Teicher, E.A. Sotomayor, Z.D. Huang Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease Cancer Res 52 1992 6702 6704
54. M. Bischof, A. Abdollahi, P. Gong Triple combination of irradiation, chemotherapy (pemetrexed), and VEGFR inhibition (SU5416) in human endothelial and tumor cells Int J Radiat Oncol Biol Phys 60 2004 1220 1232
55. P.E. Huber, M. Bischof, J. Jenne Trimodal cancer treatment Beneficial effects of combined antiangiogenesis, radiation, and chemotherapy Cancer Res 65 2005 3643 3655