메뉴 건너뛰기




Volumn 32, Issue 14, 1996, Pages 2438-2450

Reciprocal paracrine interactions between tumour cells and endothelial cells: The 'angiogenesis progression' hypothesis

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; COLORECTAL CARCINOMA; ENDOTHELIUM CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; MUTANT; ONCOGENE; PRIORITY JOURNAL; REVIEW; TUMOR CELL; TUMOR GROWTH;

EID: 0030484797     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(96)00396-6     Document Type: Article
Times cited : (195)

References (149)
  • 1
    • 0026731996 scopus 로고
    • The significance of spontaneous and induced apoptosis in the gastrointestinal tract of mice
    • 1. Potten CS. The significance of spontaneous and induced apoptosis in the gastrointestinal tract of mice. Cancer Metast Rev 1992, 11, 179-195.
    • (1992) Cancer Metast Rev , vol.11 , pp. 179-195
    • Potten, C.S.1
  • 2
    • 0028981086 scopus 로고
    • WAF1/CIP1 expression in normal and neoplastic tissues
    • WAF1/CIP1 expression in normal and neoplastic tissues. Cancer Res 1995, 55, 2910-2919.
    • (1995) Cancer Res , vol.55 , pp. 2910-2919
    • El-Deiry, W.S.1    Tokino, T.2    Waldman, T.3
  • 3
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • 3. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990, 61, 759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 4
    • 0002112642 scopus 로고
    • Molecular abnormalities in colon and rectal cancer
    • Mendelsohn J, Howley PM, Israel MA, Liotta LA, eds. Philadelphia, W.B. Saunders
    • 4. Fearon ER. Molecular abnormalities in colon and rectal cancer. In Mendelsohn J, Howley PM, Israel MA, Liotta LA, eds. The Molecular Basis of Cancer. Philadelphia, W.B. Saunders, 1995, 340-357.
    • (1995) The Molecular Basis of Cancer , pp. 340-357
    • Fearon, E.R.1
  • 5
    • 0027521847 scopus 로고
    • Pathways of ras function: Connections to the actin cytoskeleton
    • 5. Prendergast GC, Gibbs JB. Pathways of ras function: connections to the actin cytoskeleton. Adv Cancer Res 1993, 62, 19-64.
    • (1993) Adv Cancer Res , vol.62 , pp. 19-64
    • Prendergast, G.C.1    Gibbs, J.B.2
  • 6
    • 0029951444 scopus 로고    scopus 로고
    • Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events
    • 6. Kang J-S, Krauss RS. Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events. Mol Cell Biol 1996, 16, 3370-3380.
    • (1996) Mol Cell Biol , vol.16 , pp. 3370-3380
    • Kang, J.-S.1    Krauss, R.S.2
  • 7
    • 0030042598 scopus 로고    scopus 로고
    • Regulation of the cell cycle machinery by oncogenic ras
    • 7. Winston JT, Coats SR, Wang Y-Z, Pledger WJ. Regulation of the cell cycle machinery by oncogenic ras. Oncogene 1996, 12, 127-134.
    • (1996) Oncogene , vol.12 , pp. 127-134
    • Winston, J.T.1    Coats, S.R.2    Wang, Y.-Z.3    Pledger, W.J.4
  • 8
    • 0029562231 scopus 로고
    • Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: Suppression by expression of a mutant c-H-ras oncogene
    • 8. Rak J, Mituhashi Y, Erdos V, Huang S-N, Filmus J, Kerbel RS. Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by expression of a mutant c-H-ras oncogene. J Cell Biol 1995, 131, 1587-1598.
    • (1995) J Cell Biol , vol.131 , pp. 1587-1598
    • Rak, J.1    Mituhashi, Y.2    Erdos, V.3    Huang, S.-N.4    Filmus, J.5    Kerbel, R.S.6
  • 9
    • 0028822834 scopus 로고
    • Mutant ras oncogenes upregulate VEGF/VPF expression: Implications for induction and inhibition of tumor angiogenesis
    • 9. Rak J, Mitsuhashi Y, Bayko L, Filmus J, Sasazuki T, Kerbel RS. Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis. Cancer Res 1995, 55, 4575-4580.
    • (1995) Cancer Res , vol.55 , pp. 4575-4580
    • Rak, J.1    Mitsuhashi, Y.2    Bayko, L.3    Filmus, J.4    Sasazuki, T.5    Kerbel, R.S.6
  • 10
    • 0028834638 scopus 로고
    • Both v-Ha-ras and v-raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells
    • 10. Grugel S, Finkenzeller G, Weindel K, Barleon B, Marme D. Both v-Ha-ras and v-raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells. J Biol Chem 1995, 270, 25915-25919.
    • (1995) J Biol Chem , vol.270 , pp. 25915-25919
    • Grugel, S.1    Finkenzeller, G.2    Weindel, K.3    Barleon, B.4    Marme, D.5
  • 11
    • 0011482212 scopus 로고    scopus 로고
    • Impact of the cyclin dependent kinase inhibitor p27Kip1 on adhesion-dependent resistance of tumor cells to anticancer agents
    • in press
    • 11. St. Croix B, Florenes VA, Rak JW, et al. Impact of the cyclin dependent kinase inhibitor p27Kip1 on adhesion-dependent resistance of tumor cells to anticancer agents. Nature Medicine, in press.
    • Nature Medicine
    • St. Croix, B.1    Florenes, V.A.2    Rak, J.W.3
  • 12
    • 0029996726 scopus 로고    scopus 로고
    • Resistance to apoptosis conferred by cdk inhibitors during myocyte differentiation
    • 12. Wang J, Walsh K. Resistance to apoptosis conferred by cdk inhibitors during myocyte differentiation. Science 1996, 273, 359-361.
    • (1996) Science , vol.273 , pp. 359-361
    • Wang, J.1    Walsh, K.2
  • 13
    • 0028856579 scopus 로고
    • Liver endothelial cells participate in T-cell-dependent host resistance to lymphoma metastasis by production of nitric oxide in vivo
    • 13. Rocha M, Kruger A, Van Rooijen N, Schirrmacher V, Umansky V. Liver endothelial cells participate in T-cell-dependent host resistance to lymphoma metastasis by production of nitric oxide in vivo. Int J Cancer 1995, 63, 405-411.
    • (1995) Int J Cancer , vol.63 , pp. 405-411
    • Rocha, M.1    Kruger, A.2    Van Rooijen, N.3    Schirrmacher, V.4    Umansky, V.5
  • 14
    • 0029916932 scopus 로고    scopus 로고
    • WAF1 is required for survival of differentiating neuroblastoma cells
    • WAF1 is required for survival of differentiating neuroblastoma cells. Mol Cell Biol 1996, 16, 1335-1341.
    • (1996) Mol Cell Biol , vol.16 , pp. 1335-1341
    • Poluha, W.1    Poluha, D.K.2    Chang, B.3
  • 15
    • 0029957019 scopus 로고    scopus 로고
    • A non-enzymatic p21 protein inhibitor of stress-activated protein kinases
    • 15. Shim J, Lee H, Park J, Kim H, Choi E-J. A non-enzymatic p21 protein inhibitor of stress-activated protein kinases. Nature 1996, 381, 804-807.
    • (1996) Nature , vol.381 , pp. 804-807
    • Shim, J.1    Lee, H.2    Park, J.3    Kim, H.4    Choi, E.-J.5
  • 16
    • 0030025772 scopus 로고    scopus 로고
    • Life (and death) in a malignant tumour
    • 16. Kinzler KW, Vogelstein B. Life (and death) in a malignant tumour. Nature 1996, 379, 19-20.
    • (1996) Nature , vol.379 , pp. 19-20
    • Kinzler, K.W.1    Vogelstein, B.2
  • 17
    • 0030025773 scopus 로고    scopus 로고
    • Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
    • 17. Graeber TG, Osmanian C, Jacks T. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours. Nature 1996, 379, 88-91.
    • (1996) Nature , vol.379 , pp. 88-91
    • Graeber, T.G.1    Osmanian, C.2    Jacks, T.3
  • 18
    • 0029128416 scopus 로고
    • The modulation of thrombospondin and other naturally occurring inhibitors of angiogenesis during tumor progression
    • 18. Volpert OV, Stellmach V, Bouck N. The modulation of thrombospondin and other naturally occurring inhibitors of angiogenesis during tumor progression. Breast Cancer Res Treat 1995, 36, 119-126.
    • (1995) Breast Cancer Res Treat , vol.36 , pp. 119-126
    • Volpert, O.V.1    Stellmach, V.2    Bouck, N.3
  • 19
    • 0027958348 scopus 로고
    • Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression
    • 19. Kieser A, Weich HA, Brandner G, Marme D, Kolch W. Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression. Oncogene 1994, 9, 963-969.
    • (1994) Oncogene , vol.9 , pp. 963-969
    • Kieser, A.1    Weich, H.A.2    Brandner, G.3    Marme, D.4    Kolch, W.5
  • 20
    • 0028865988 scopus 로고
    • Wild-type p53 and v-src exert opposing influences on human vascular endothelial growth factor gene expression
    • 20. Mukhopadhyay D, Tsiokas L, Sukhatme VP. Wild-type p53 and v-src exert opposing influences on human vascular endothelial growth factor gene expression. Cancer Res 1995, 55, 6161-6165.
    • (1995) Cancer Res , vol.55 , pp. 6161-6165
    • Mukhopadhyay, D.1    Tsiokas, L.2    Sukhatme, V.P.3
  • 22
    • 0029117223 scopus 로고
    • Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells
    • 22. Ikeda E, Achen MG, Breier G, Risau W. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J Biol Chem 1995, 270, 19761-19766.
    • (1995) J Biol Chem , vol.270 , pp. 19761-19766
    • Ikeda, E.1    Achen, M.G.2    Breier, G.3    Risau, W.4
  • 23
    • 0028897916 scopus 로고
    • Hypoxia-induced transcription of the vascular endothelial growth factor gene is independent of functional AP-1 transcription factor
    • 23. Finkenzeller G, Technau A, Marme D. Hypoxia-induced transcription of the vascular endothelial growth factor gene is independent of functional AP-1 transcription factor. Biochem Biophys Res Commun 1995, 208, 432-439.
    • (1995) Biochem Biophys Res Commun , vol.208 , pp. 432-439
    • Finkenzeller, G.1    Technau, A.2    Marme, D.3
  • 24
    • 0026485002 scopus 로고
    • Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
    • 24. Shweiki D, Itin A, Soffer D, Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 1992, 359, 843-845.
    • (1992) Nature , vol.359 , pp. 843-845
    • Shweiki, D.1    Itin, A.2    Soffer, D.3    Keshet, E.4
  • 25
    • 0028870050 scopus 로고
    • Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: Implications for tumor angiogenesis
    • 25. Shweiki D, Neeman M, Itin A, Keshet E. Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis. Proc Natl Acad Sci USA 1995, 92, 768-772.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 768-772
    • Shweiki, D.1    Neeman, M.2    Itin, A.3    Keshet, E.4
  • 26
    • 0029082384 scopus 로고
    • Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes
    • 26. Stein I, Neeman M, Shweiki D, Itin A, Keshet E. Stabilization of vascular endothelial growth factor mRNA by hypoxia and hypoglycemia and coregulation with other ischemia-induced genes. Mol Cell Biol 1995, 15, 5363-5368.
    • (1995) Mol Cell Biol , vol.15 , pp. 5363-5368
    • Stein, I.1    Neeman, M.2    Shweiki, D.3    Itin, A.4    Keshet, E.5
  • 27
    • 0028803509 scopus 로고
    • Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity
    • 27. Alon T, Hemo I, Itin A, Pe'er J, Stone J, Keshet E. Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity. Nature Medicine 1995, 1, 1024-1028.
    • (1995) Nature Medicine , vol.1 , pp. 1024-1028
    • Alon, T.1    Hemo, I.2    Itin, A.3    Pe'er, J.4    Stone, J.5    Keshet, E.6
  • 28
    • 84970070220 scopus 로고
    • Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity metastasis, and proliferation of human colon cancer
    • 28. Takashashi Y, Kitadai Y, Bucana CD, Cleary KR, Ellis LM. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity metastasis, and proliferation of human colon cancer. Cancer Res 1995, 55, 3964-3968.
    • (1995) Cancer Res , vol.55 , pp. 3964-3968
    • Takashashi, Y.1    Kitadai, Y.2    Bucana, C.D.3    Cleary, K.R.4    Ellis, L.M.5
  • 29
    • 0030037264 scopus 로고    scopus 로고
    • Angiogenesis as an unfavorable prognostic factor in human colorectal carcinoma
    • 29. Takebayashi Y, Akiyama S-i, Yamada K, Akiba S, Aikou T. Angiogenesis as an unfavorable prognostic factor in human colorectal carcinoma. Cancer 1996, 78, 226-231.
    • (1996) Cancer , vol.78 , pp. 226-231
    • Takebayashi, Y.1    Akiyama, S.-I.2    Yamada, K.3    Akiba, S.4    Aikou, T.5
  • 30
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis-dependent?
    • 30. Folkman J. What is the evidence that tumors are angiogenesis-dependent? J Natl Cancer Inst 1989, 82, 4-6.
    • (1989) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 31
    • 0024510367 scopus 로고
    • Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ
    • 31. Thompson TC, Southgate J, Kitchener G, Land H. Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ. Cell 1989, 56, 917-930.
    • (1989) Cell , vol.56 , pp. 917-930
    • Thompson, T.C.1    Southgate, J.2    Kitchener, G.3    Land, H.4
  • 32
    • 0024549349 scopus 로고
    • Induction of angiogenesis during transition from hyperplasia to neoplasia
    • 32. Folkman J, Watson K, Ingber D, Hanahan D. Induction of angiogenesis during transition from hyperplasia to neoplasia. Nature 1989, 339, 58-61.
    • (1989) Nature , vol.339 , pp. 58-61
    • Folkman, J.1    Watson, K.2    Ingber, D.3    Hanahan, D.4
  • 33
    • 0028856096 scopus 로고
    • Vascular endothelial growth factor and its receptors, flt-1 and flk-1, are expressed in normal pancreatic islets and throughout islet cell tumorigenesis
    • 33. Christofori G, Naik P, Hanahan D. Vascular endothelial growth factor and its receptors, flt-1 and flk-1, are expressed in normal pancreatic islets and throughout islet cell tumorigenesis. Mol Endocrinol 1995, 9, 1760-1770.
    • (1995) Mol Endocrinol , vol.9 , pp. 1760-1770
    • Christofori, G.1    Naik, P.2    Hanahan, D.3
  • 34
    • 0025913891 scopus 로고
    • Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma
    • 34. Kandel J, Bossy-Wetzel E, Radvanyi F, Klagsbrun M, Folkman J, Hanahan D. Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma. Cell 1991, 66, 1095-1104.
    • (1991) Cell , vol.66 , pp. 1095-1104
    • Kandel, J.1    Bossy-Wetzel, E.2    Radvanyi, F.3    Klagsbrun, M.4    Folkman, J.5    Hanahan, D.6
  • 35
    • 33749742038 scopus 로고    scopus 로고
    • The rise and fall of apoptosis during multi-stage tumorigenesis: Down-modulation contributes to tumor progression from angiogenic progenitors
    • in press
    • 35. Naik P, Karrim J, Hanahan D. The rise and fall of apoptosis during multi-stage tumorigenesis: down-modulation contributes to tumor progression from angiogenic progenitors. Genes Develop, in press.
    • Genes Develop
    • Naik, P.1    Karrim, J.2    Hanahan, D.3
  • 36
    • 0028818712 scopus 로고
    • Tumor suppressor loci on mouse chromosomes 9 and 16 are lost at distinct stages of tumorigenesis in a transgenic model of islet cell carcinoma
    • 36. Parangi S, Dietrich W, Christofori G, Lander ES, Hanahan D. Tumor suppressor loci on mouse chromosomes 9 and 16 are lost at distinct stages of tumorigenesis in a transgenic model of islet cell carcinoma. Cancer Res 1995, 55, 6071-6076.
    • (1995) Cancer Res , vol.55 , pp. 6071-6076
    • Parangi, S.1    Dietrich, W.2    Christofori, G.3    Lander, E.S.4    Hanahan, D.5
  • 38
    • 0029068339 scopus 로고
    • Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation
    • 38. Mukhopadhyay D, Tsiokas L, Zhou X-M, Foster D, Brugge JS, Sukhatme VP. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation. Nature 1995, 375, 577-581.
    • (1995) Nature , vol.375 , pp. 577-581
    • Mukhopadhyay, D.1    Tsiokas, L.2    Zhou, X.-M.3    Foster, D.4    Brugge, J.S.5    Sukhatme, V.P.6
  • 39
    • 0027353383 scopus 로고
    • Non-nuclear oncogenes and the regulation of gene expression in transformed cells
    • 39. Bortner DM, Langer SJ, Ostrowski MC. Non-nuclear oncogenes and the regulation of gene expression in transformed cells. Crit Rev Oncogen 1993, 4, 137-160.
    • (1993) Crit Rev Oncogen , vol.4 , pp. 137-160
    • Bortner, D.M.1    Langer, S.J.2    Ostrowski, M.C.3
  • 40
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and H-ras that binds and phosphorylates the c-jun activation domain
    • 40. Derijard B, Hibi M, Wu I-H. JNK1: a protein kinase stimulated by UV light and H-ras that binds and phosphorylates the c-jun activation domain. Cell 1994, 76, 1025-1037.
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.-H.3
  • 41
    • 0001830867 scopus 로고
    • Tumor angiogenesis
    • Mendelsohn J, Howley PM, Israel MA, Liotta LA, eds. Philadelphia, W.B. Saunders
    • 41. Folkman J. Tumor angiogenesis. In Mendelsohn J, Howley PM, Israel MA, Liotta LA, eds. The Molecular Basis of Cancer. Philadelphia, W.B. Saunders, 1995, 206-232.
    • (1995) The Molecular Basis of Cancer , pp. 206-232
    • Folkman, J.1
  • 42
    • 0023157363 scopus 로고
    • Angiogenic factors
    • 42. Folkman J, Klagsbrun M. Angiogenic factors. Science 1987, 235, 442-447.
    • (1987) Science , vol.235 , pp. 442-447
    • Folkman, J.1    Klagsbrun, M.2
  • 43
    • 0025981665 scopus 로고
    • Structure of solid tumors and their vasculature: Implications for therapy with monoclonal antibodies
    • 43. Dvorak HF, Nagy JA, Dvorak AM. Structure of solid tumors and their vasculature: implications for therapy with monoclonal antibodies. Cancer Cells 1991, 3, 77-85.
    • (1991) Cancer Cells , vol.3 , pp. 77-85
    • Dvorak, H.F.1    Nagy, J.A.2    Dvorak, A.M.3
  • 45
    • 0029085337 scopus 로고
    • Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: A potential role for T cells in angiogenesis
    • 45. Freeman MR, Schneck FX, Gagnon ML. Peripheral blood T lymphocytes and lymphocytes infiltrating human cancers express vascular endothelial growth factor: a potential role for T cells in angiogenesis. Cancer Res 1995, 55, 4140-4145.
    • (1995) Cancer Res , vol.55 , pp. 4140-4145
    • Freeman, M.R.1    Schneck, F.X.2    Gagnon, M.L.3
  • 46
    • 0027960791 scopus 로고
    • Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression
    • 46. Hlatky L, Tsionou C, Hahnfeldt P, Coleman CN. Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression. Cancer Res 1994, 54, 6083-6086.
    • (1994) Cancer Res , vol.54 , pp. 6083-6086
    • Hlatky, L.1    Tsionou, C.2    Hahnfeldt, P.3    Coleman, C.N.4
  • 47
    • 0028910567 scopus 로고
    • Consequences of angiogenesis for tumor progression, metastasis and cancer therapy
    • 47. Rak J, St Croix B, Kerbel RS. Consequences of angiogenesis for tumor progression, metastasis and cancer therapy. Anti-Cancer Drugs 1995, 6, 3-18.
    • (1995) Anti-cancer Drugs , vol.6 , pp. 3-18
    • Rak, J.1    St Croix, B.2    Kerbel, R.S.3
  • 48
    • 0028321632 scopus 로고
    • Infrequent K-ras activation in superficial-type (flat) colorectal adenomas and adenocarcinomas
    • 48. Minamoto T, Sawaguchi K, Mai M, Yamashita N, Sugimura T, Esumi H. Infrequent K-ras activation in superficial-type (flat) colorectal adenomas and adenocarcinomas. Cancer Res 1994, 54, 2841-2844.
    • (1994) Cancer Res , vol.54 , pp. 2841-2844
    • Minamoto, T.1    Sawaguchi, K.2    Mai, M.3    Yamashita, N.4    Sugimura, T.5    Esumi, H.6
  • 49
    • 0028965641 scopus 로고
    • K-ras gene mutations in early colorectal cancer. . . flat elevated vs polyp-forming cancer
    • 49. Hasegawa H, Ueda M, Watanabe M, Teramoto T, Mukai M, Kitajima M. K-ras gene mutations in early colorectal cancer. . . flat elevated vs polyp-forming cancer . . . . Oncogene 1995, 10, 1413-1416.
    • (1995) Oncogene , vol.10 , pp. 1413-1416
    • Hasegawa, H.1    Ueda, M.2    Watanabe, M.3    Teramoto, T.4    Mukai, M.5    Kitajima, M.6
  • 50
    • 0027905014 scopus 로고
    • Altered growth of human colon cancer cell lines disrupted at activated Ki-ras
    • 50. Shirasawa S, Furuse M, Yokoyama N, Sasazuki T. Altered growth of human colon cancer cell lines disrupted at activated Ki-ras. Science 1993, 260, 85-88.
    • (1993) Science , vol.260 , pp. 85-88
    • Shirasawa, S.1    Furuse, M.2    Yokoyama, N.3    Sasazuki, T.4
  • 52
    • 0027225651 scopus 로고
    • Relationship of levels and kinetics of H-ras expression to transformed phenotype and loss of TGF-β-mediated growth regulation in intestinal epithelial cells
    • 52. Zhao J, Buick RN. Relationship of levels and kinetics of H-ras expression to transformed phenotype and loss of TGF-β-mediated growth regulation in intestinal epithelial cells. Exp Cell Res 1993, 204, 82-87.
    • (1993) Exp Cell Res , vol.204 , pp. 82-87
    • Zhao, J.1    Buick, R.N.2
  • 55
    • 0343815541 scopus 로고
    • Tumor growth and cell kinetics
    • Tannock IF, Hill RP, eds. Toronto, Pergamon Press
    • 55. Tannock IF. Tumor growth and cell kinetics. In Tannock IF, Hill RP, eds. The Basic Science of Oncology. Toronto, Pergamon Press, 1995, 140-159.
    • (1995) The Basic Science of Oncology , pp. 140-159
    • Tannock, I.F.1
  • 56
    • 0028941441 scopus 로고
    • Inhibition of apoptosis during development of colorectal cancer
    • 56. Bedi A, Pasricha PJ, Akhtar AJ. Inhibition of apoptosis during development of colorectal cancer. Cancer Res 1995, 55, 1811-1816.
    • (1995) Cancer Res , vol.55 , pp. 1811-1816
    • Bedi, A.1    Pasricha, P.J.2    Akhtar, A.J.3
  • 57
    • 0027246039 scopus 로고
    • Defining the critical gene expression changes associated with expression and suppression of the tumorigenic and metastatic phenotype in Ha-ras-transformed cloned rat embryo fibroblast cells
    • 57. Su Z-Z, Austin VN, Zimmer SG, Fisher PB. Defining the critical gene expression changes associated with expression and suppression of the tumorigenic and metastatic phenotype in Ha-ras-transformed cloned rat embryo fibroblast cells. Oncogene 1993, 8, 1211-1219.
    • (1993) Oncogene , vol.8 , pp. 1211-1219
    • Su, Z.-Z.1    Austin, V.N.2    Zimmer, S.G.3    Fisher, P.B.4
  • 58
    • 0027395018 scopus 로고
    • Role of transforming growth factor alpha (TGF-α) in the transformation of ras-transfected rat intestinal epithelial cells
    • 58. Filmus J, Shi W, Spencer T. Role of transforming growth factor alpha (TGF-α) in the transformation of ras-transfected rat intestinal epithelial cells. Oncogene 1993, 8, 1017-1022.
    • (1993) Oncogene , vol.8 , pp. 1017-1022
    • Filmus, J.1    Shi, W.2    Spencer, T.3
  • 59
    • 0022414709 scopus 로고
    • Pharmacokinetics, binding and distribution of Hoechst 33342 in spheroids and murine tumours
    • 59. Olive PL, Chaplin DJ, Durand RE. Pharmacokinetics, binding and distribution of Hoechst 33342 in spheroids and murine tumours. Br J Cancer 1985, 52, 739-746.
    • (1985) Br J Cancer , vol.52 , pp. 739-746
    • Olive, P.L.1    Chaplin, D.J.2    Durand, R.E.3
  • 60
    • 0027491056 scopus 로고
    • Growth advantage ('clonal dominance') of metastatically-competent tumor cell variants expressed under selective two or three dimensional tissue culture conditions
    • 60. Rak JW, Kerbel RS. Growth advantage ('clonal dominance') of metastatically-competent tumor cell variants expressed under selective two or three dimensional tissue culture conditions. In Vitro Cell Dev Biol 1993, 29A, 742-748.
    • (1993) In Vitro Cell Dev Biol , vol.29 A , pp. 742-748
    • Rak, J.W.1    Kerbel, R.S.2
  • 61
    • 0028872649 scopus 로고
    • Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
    • 61. Marshall CJ. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 1995, 80, 179-185.
    • (1995) Cell , vol.80 , pp. 179-185
    • Marshall, C.J.1
  • 62
    • 0028884084 scopus 로고
    • Evidence for cell-specific differences in transformation by N-, H-and K-ras
    • 62. Maher J, Baker DA, Manning M, Dibb NJ, Roberts IAG. Evidence for cell-specific differences in transformation by N-, H-and K-ras. Oncogene 1995, 11, 1639-1647.
    • (1995) Oncogene , vol.11 , pp. 1639-1647
    • Maher, J.1    Baker, D.A.2    Manning, M.3    Dibb, N.J.4    Roberts, I.A.G.5
  • 64
    • 0024261027 scopus 로고
    • Efficacy of antibodies to epidermal growth factor receptor against KB carcinoma in vitro and in nude mice
    • 64. Aboud-Pirak E, Hurwitz E, Pirak ME, Bellot F, Schlessinger J, Sela M. Efficacy of antibodies to epidermal growth factor receptor against KB carcinoma in vitro and in nude mice. J Natl Cancer Inst 1988, 80, 1605-1611.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 1605-1611
    • Aboud-Pirak, E.1    Hurwitz, E.2    Pirak, M.E.3    Bellot, F.4    Schlessinger, J.5    Sela, M.6
  • 65
    • 0029886350 scopus 로고    scopus 로고
    • In vitro and in vivo anti-tumour effects of a humanised monoclonal antibody against c-erbB-2 product
    • 65. Tokuda Y, Ohnishi Y, Shimamura K. In vitro and in vivo anti-tumour effects of a humanised monoclonal antibody against c-erbB-2 product. Br J Cancer 1996, 73, 1362-1365.
    • (1996) Br J Cancer , vol.73 , pp. 1362-1365
    • Tokuda, Y.1    Ohnishi, Y.2    Shimamura, K.3
  • 66
    • 0028141496 scopus 로고
    • Transformation of mammalian cells by constitutively active MAP kinase kinase
    • 66. Mansour SJ, Matten WT, Hermann AS. Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 1994, 265, 966.
    • (1994) Science , vol.265 , pp. 966
    • Mansour, S.J.1    Matten, W.T.2    Hermann, A.S.3
  • 67
    • 0028079956 scopus 로고
    • Constitutively active mutants of MAP kinase kinase (MEK1) induce growth factor-relaxation and oncogenicity when expressed in fibroblasts
    • 67. Brunet A, Pages G, Pouyssegur J. Constitutively active mutants of MAP kinase kinase (MEK1) induce growth factor-relaxation and oncogenicity when expressed in fibroblasts. Oncogene 1994, 9, 3379-3387.
    • (1994) Oncogene , vol.9 , pp. 3379-3387
    • Brunet, A.1    Pages, G.2    Pouyssegur, J.3
  • 68
    • 0029959434 scopus 로고    scopus 로고
    • Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells
    • 68. Oldham SM, Clark GJ, Gangarosa LM, Coffey RJ Jr, Der CJ. Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells. Proc Natl Acad Sci USA 1996, 93, 6924-6928.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 6924-6928
    • Oldham, S.M.1    Clark, G.J.2    Gangarosa, L.M.3    Coffey R.J., Jr.4    Der, C.J.5
  • 69
    • 0025739937 scopus 로고
    • Biochemical properties of vascular endothelial cells
    • 69. Borsum T. Biochemical properties of vascular endothelial cells. Virchows Arch B Cell Pathol 1991, 60, 279-286.
    • (1991) Virchows Arch B Cell Pathol , vol.60 , pp. 279-286
    • Borsum, T.1
  • 70
    • 0000801529 scopus 로고
    • The role of angiogenesis in tumor progression and metastasis
    • Heppner GH, ed. JAI Press, Inc.
    • 70. Rak JW, Hegmann EJ, Kerbel RS. The role of angiogenesis in tumor progression and metastasis. In Heppner GH, ed. Advances in Molecular and Cell Biology. JAI Press, Inc., 1993, 205-251.
    • (1993) Advances in Molecular and Cell Biology , pp. 205-251
    • Rak, J.W.1    Hegmann, E.J.2    Kerbel, R.S.3
  • 71
    • 0025739765 scopus 로고
    • Autocrine effects of fibroblast growth factor in repair of radiation damage in endothelial cells
    • 71. Haimovitz-Friedman A, Vlodavsky I, Chaudhuri A, Witte L, Fuks Z. Autocrine effects of fibroblast growth factor in repair of radiation damage in endothelial cells. Cancer Res 1991, 51, 2552-2558.
    • (1991) Cancer Res , vol.51 , pp. 2552-2558
    • Haimovitz-Friedman, A.1    Vlodavsky, I.2    Chaudhuri, A.3    Witte, L.4    Fuks, Z.5
  • 72
    • 0027980356 scopus 로고
    • A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1)
    • 72. Yamane A, Seetharam L, Yamaguchi S. A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1). Oncogene 1994, 9, 2683-2690.
    • (1994) Oncogene , vol.9 , pp. 2683-2690
    • Yamane, A.1    Seetharam, L.2    Yamaguchi, S.3
  • 74
    • 0030031898 scopus 로고    scopus 로고
    • Expression of vascular permeability factor/vascular endothelial growth factor on melanoma cells increases tumor growth, angiogenesis, and experimental metastasis
    • 74. Claffey KP, Brown LF, del Aguila LF. Expression of vascular permeability factor/vascular endothelial growth factor on melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res 1996, 56, 172-181.
    • (1996) Cancer Res , vol.56 , pp. 172-181
    • Claffey, K.P.1    Brown, L.F.2    Del Aguila, L.F.3
  • 75
    • 0028067243 scopus 로고
    • Paracrine interactions between fibroblasts and endothelial cells in a serum-free coculture model
    • 75. Villaschi S, Nicosia RF. Paracrine interactions between fibroblasts and endothelial cells in a serum-free coculture model. Lab Invest 1994, 71, 291-299.
    • (1994) Lab Invest , vol.71 , pp. 291-299
    • Villaschi, S.1    Nicosia, R.F.2
  • 76
    • 0001505189 scopus 로고
    • An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes
    • 76. Antonelli-Orlidge A, Saunders KB, Smith SR, D'Amore PA. An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes. Proc Natl Acad Sci USA 1989, 86, 4544-4548.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 4544-4548
    • Antonelli-Orlidge, A.1    Saunders, K.B.2    Smith, S.R.3    D'Amore, P.A.4
  • 77
    • 0027469418 scopus 로고
    • Development of resistance mechanisms to the growth inhibitory effects of transforming growth factor-β during tumor progression
    • 77. Filmus J, Kerbel RS. Development of resistance mechanisms to the growth inhibitory effects of transforming growth factor-β during tumor progression. Curr Opin Oncol 1993, 5, 123-129.
    • (1993) Curr Opin Oncol , vol.5 , pp. 123-129
    • Filmus, J.1    Kerbel, R.S.2
  • 78
    • 0026768120 scopus 로고
    • Basic fibroblast growth factor-induced activation of latent transforming growth factor β in endothelial cells: Regulation of plasminogen activator activity
    • 78. Flaumenhaft R, Abe M, Mignatti P, Rifkin DB. Basic fibroblast growth factor-induced activation of latent transforming growth factor β in endothelial cells: regulation of plasminogen activator activity. J Cell Biol 1992, 118, 901-909.
    • (1992) J Cell Biol , vol.118 , pp. 901-909
    • Flaumenhaft, R.1    Abe, M.2    Mignatti, P.3    Rifkin, D.B.4
  • 79
    • 0028157338 scopus 로고
    • Matrix-bound thrombospondin promotes angiogenesis in vitro
    • 79. Nicosia RF, Tuszynski GP. Matrix-bound thrombospondin promotes angiogenesis in vitro. J Cell Biol 1994, 124, 183-193.
    • (1994) J Cell Biol , vol.124 , pp. 183-193
    • Nicosia, R.F.1    Tuszynski, G.P.2
  • 80
    • 0011489974 scopus 로고
    • Interactions between cancer cells and the endothelium
    • Orr, S, Weiss L, eds. Boca Raton, CRC press
    • 80. Auerbach R. Interactions between cancer cells and the endothelium. In Orr, S, Weiss L, eds. Microcirculation in Cancer Metastasis. Boca Raton, CRC press, 1991, 169-181.
    • (1991) Microcirculation in Cancer Metastasis , pp. 169-181
    • Auerbach, R.1
  • 81
    • 0028840521 scopus 로고
    • Between molecules and morphology
    • 81. Vernon RB, Sage EH. Between molecules and morphology. Am J Pathol 1995, 147, 873-883.
    • (1995) Am J Pathol , vol.147 , pp. 873-883
    • Vernon, R.B.1    Sage, E.H.2
  • 82
    • 0026069593 scopus 로고
    • Direct in vitro lysis of metastatic tumor cells by cytokine-activated murine vascular endothelial cells
    • 82. Li L, Nicolson GL, Fidler IJ. Direct in vitro lysis of metastatic tumor cells by cytokine-activated murine vascular endothelial cells. Cancer Res 1991, 51, 245-254.
    • (1991) Cancer Res , vol.51 , pp. 245-254
    • Li, L.1    Nicolson, G.L.2    Fidler, I.J.3
  • 83
    • 0025286753 scopus 로고
    • Tumor interactions with the vasculature: Angiogenesis and tumor metastasis
    • 83. Blood CH, Zetter BR. Tumor interactions with the vasculature: angiogenesis and tumor metastasis. Bioch Biophys Acta 1990, 1032, 89-118.
    • (1990) Bioch Biophys Acta , vol.1032 , pp. 89-118
    • Blood, C.H.1    Zetter, B.R.2
  • 84
    • 0026704498 scopus 로고
    • Separable growth and migration factors for large-cell lymphoma cells secreted by microvascular endothelial cells derived from target organs for metastasis
    • 84. Hamada J, Cavanaugh PG, Lotan O, Nicolson GL. Separable growth and migration factors for large-cell lymphoma cells secreted by microvascular endothelial cells derived from target organs for metastasis. Br J Cancer 1992, 66, 349-354.
    • (1992) Br J Cancer , vol.66 , pp. 349-354
    • Hamada, J.1    Cavanaugh, P.G.2    Lotan, O.3    Nicolson, G.L.4
  • 85
    • 0027818475 scopus 로고
    • A paracrine migration-stimulating factor for metastatic tumor cells secreted by mouse hepatic sinusoidal endothelial cells: Identification as complement component C3b
    • 85. Hamada J-I, Cavanaugh PG, Miki K, Nicolson GL. A paracrine migration-stimulating factor for metastatic tumor cells secreted by mouse hepatic sinusoidal endothelial cells: identification as complement component C3b. Cancer Res 1993, 53, 4418-4423.
    • (1993) Cancer Res , vol.53 , pp. 4418-4423
    • Hamada, J.-I.1    Cavanaugh, P.G.2    Miki, K.3    Nicolson, G.L.4
  • 86
    • 0020621330 scopus 로고
    • Angiogenesis-dependent tumor spread in reinforced fibrin clot culture
    • 86. Nicosia RF, Tchao R, Leighton J. Angiogenesis-dependent tumor spread in reinforced fibrin clot culture. Cancer Res 1983, 43, 2159-2166.
    • (1983) Cancer Res , vol.43 , pp. 2159-2166
    • Nicosia, R.F.1    Tchao, R.2    Leighton, J.3
  • 87
    • 0022610896 scopus 로고
    • Interactions between newly formed endothelial channels and carcinoma cells in plasma clot culture
    • 87. Nicosia RF, Tchao R, Leighton J. Interactions between newly formed endothelial channels and carcinoma cells in plasma clot culture. Clin Exp Metastasis 1986, 4, 91-104.
    • (1986) Clin Exp Metastasis , vol.4 , pp. 91-104
    • Nicosia, R.F.1    Tchao, R.2    Leighton, J.3
  • 88
    • 0028335948 scopus 로고
    • Anchorage dependence, integrins, and apoptosis
    • 88. Ruoslahti E, Reed JC. Anchorage dependence, integrins, and apoptosis. Cell 1994, 77, 477-478.
    • (1994) Cell , vol.77 , pp. 477-478
    • Ruoslahti, E.1    Reed, J.C.2
  • 89
    • 0028670833 scopus 로고
    • Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • 89. Brooks PC, Montgomery AMP, Rosenfeld M. Integrin αvβ3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994, 79, 1157-1164.
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1    Montgomery, A.M.P.2    Rosenfeld, M.3
  • 92
    • 0025212688 scopus 로고
    • Pattern of interleukin 6 gene expression in vivo suggests a role for this cytokine in angiogenesis
    • 92. Motro B, Itin A, Sachs L, Keshet E. Pattern of interleukin 6 gene expression in vivo suggests a role for this cytokine in angiogenesis. Proc Natl Acad Sci USA 1990, 87, 3092-3096.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3092-3096
    • Motro, B.1    Itin, A.2    Sachs, L.3    Keshet, E.4
  • 93
    • 0028345361 scopus 로고
    • Cell-adhesion-disrupting action of interleukin 6 in human ductal breast carcinoma cells
    • 93. Tamm I, Kikuchi T, Cardinale I, Krueger JG. Cell-adhesion-disrupting action of interleukin 6 in human ductal breast carcinoma cells. Proc Natl Acad Sci USA 1994, 91, 3329-3333.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3329-3333
    • Tamm, I.1    Kikuchi, T.2    Cardinale, I.3    Krueger, J.G.4
  • 94
    • 0025642960 scopus 로고
    • Suppression of programmed death and G1 arrest in B-cell hybridomas by interleukin-6 is not accompanied by altered expression immediate early response genes
    • 94. Sabourin LA, Hawley RG. Suppression of programmed death and G1 arrest in B-cell hybridomas by interleukin-6 is not accompanied by altered expression immediate early response genes. J Cell Physiol 1990, 145, 564-574.
    • (1990) J Cell Physiol , vol.145 , pp. 564-574
    • Sabourin, L.A.1    Hawley, R.G.2
  • 95
    • 0030046481 scopus 로고    scopus 로고
    • Interleukin 6 induces the expression of vascular endothelial growth factor
    • 95. Cohen T, Nahari D, Cerem LW, Neufeld G, Levi BZ. Interleukin 6 induces the expression of vascular endothelial growth factor. J Biol Chem 1996, 271, 736-741.
    • (1996) J Biol Chem , vol.271 , pp. 736-741
    • Cohen, T.1    Nahari, D.2    Cerem, L.W.3    Neufeld, G.4    Levi, B.Z.5
  • 96
    • 0025993389 scopus 로고
    • Endogenous basic fibroblast growth factor-dependent induction of collagenase and interleukin 6 in tumor necrosis factor treated human microvascular endothelial cells
    • 96. Okamura K, Sato Y, Matsuda T. Endogenous basic fibroblast growth factor-dependent induction of collagenase and interleukin 6 in tumor necrosis factor treated human microvascular endothelial cells. J Biol Chem 1991, 266, 19162-19165.
    • (1991) J Biol Chem , vol.266 , pp. 19162-19165
    • Okamura, K.1    Sato, Y.2    Matsuda, T.3
  • 97
    • 0030034383 scopus 로고    scopus 로고
    • Interleukin 6 acts as a paracrine growth factor in human mammary carcinoma cell lines
    • 97. Chiu JJ, Sgagias MK, Cowan KH. Interleukin 6 acts as a paracrine growth factor in human mammary carcinoma cell lines. Clin Cancer Res 1996, 2, 215-221.
    • (1996) Clin Cancer Res , vol.2 , pp. 215-221
    • Chiu, J.J.1    Sgagias, M.K.2    Cowan, K.H.3
  • 98
    • 0002799709 scopus 로고
    • Responsiveness of normal/dysplastic melanocytes and melanoma cells from different lesional stages of disease progression to the growth inhibitory effects of TGF-β
    • 98. MacDougall J, Kerbel RS. Responsiveness of normal/dysplastic melanocytes and melanoma cells from different lesional stages of disease progression to the growth inhibitory effects of TGF-β. Mol Cell Different 1993, 1, 21-40.
    • (1993) Mol Cell Different , vol.1 , pp. 21-40
    • MacDougall, J.1    Kerbel, R.S.2
  • 100
    • 0025909122 scopus 로고
    • Tumor progression and the nature of cancer
    • 100. Clark W. Tumor progression and the nature of cancer. Br J Cancer 1991, 64, 631-644.
    • (1991) Br J Cancer , vol.64 , pp. 631-644
    • Clark, W.1
  • 101
    • 0026064107 scopus 로고
    • Interleukins 1α and 6 and tumor necrosis factor α are paracrine inhibitors of human melanocyte proliferation and melanogenesis
    • 101. Swope VB, Abdel-Malek Z, Kassam LM, Nordlund JJ. Interleukins 1α and 6 and tumor necrosis factor α are paracrine inhibitors of human melanocyte proliferation and melanogenesis. J Invest Dermatol 1991, 96, 180-185.
    • (1991) J Invest Dermatol , vol.96 , pp. 180-185
    • Swope, V.B.1    Abdel-Malek, Z.2    Kassam, L.M.3    Nordlund, J.J.4
  • 102
    • 0026744188 scopus 로고
    • Interleukin-6: A fibroblast-derived growth inhibitor of human melanoma cells from early but not advanced stages of tumor progression
    • 102. Lu C, Vickers MF, Kerbel RS. Interleukin-6: a fibroblast-derived growth inhibitor of human melanoma cells from early but not advanced stages of tumor progression. Proc Natl Acad Sci USA 1992, 89, 9215-9219.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9215-9219
    • Lu, C.1    Vickers, M.F.2    Kerbel, R.S.3
  • 103
    • 0026731462 scopus 로고
    • Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer: Malignant melanoma as a paradigm
    • 103. Kerbel RS. Expression of multi-cytokine resistance and multi-growth factor independence in advanced stage metastatic cancer: malignant melanoma as a paradigm. Am J Pathol 1992, 141, 519-524.
    • (1992) Am J Pathol , vol.141 , pp. 519-524
    • Kerbel, R.S.1
  • 104
    • 0026538833 scopus 로고
    • Over-expression of H-ras oncogene induces resistance to the growth inhibitory action of TGF-β1 and alters the number and type of TGF-β1 receptors in rat intestinal epithelial cell clones
    • 104. Filmus J, Zhao J, Buick RN. Over-expression of H-ras oncogene induces resistance to the growth inhibitory action of TGF-β1 and alters the number and type of TGF-β1 receptors in rat intestinal epithelial cell clones. Oncogene 1992, 7, 521-526.
    • (1992) Oncogene , vol.7 , pp. 521-526
    • Filmus, J.1    Zhao, J.2    Buick, R.N.3
  • 105
    • 0023144975 scopus 로고
    • What is the role of angiogenesis in metastasis from cutaneous melanoma?
    • 105. Folkman J. What is the role of angiogenesis in metastasis from cutaneous melanoma? Eur J Cancer Clin Oncol 1987, 23, 361-363.
    • (1987) Eur J Cancer Clin Oncol , vol.23 , pp. 361-363
    • Folkman, J.1
  • 106
    • 0028263516 scopus 로고
    • Differential expression of basic fibroblast growth factor (bFGF) in melanocytic lesions demonstrated by in situ hybridization
    • 106. Reed JA, McNutt NS, Albino AP. Differential expression of basic fibroblast growth factor (bFGF) in melanocytic lesions demonstrated by in situ hybridization. Am J Pathol 1994, 144, 329-336.
    • (1994) Am J Pathol , vol.144 , pp. 329-336
    • Reed, J.A.1    McNutt, N.S.2    Albino, A.P.3
  • 107
    • 0028214655 scopus 로고
    • Progressive loss of sensitivity to endothelium-derived growth inhibitors expressed by human melanoma cells during disease progression
    • 107. Rak JW, Hegmann EJ, Lu C, Kerbel RS. Progressive loss of sensitivity to endothelium-derived growth inhibitors expressed by human melanoma cells during disease progression. J Cell Physiol 1994, 159, 245-255.
    • (1994) J Cell Physiol , vol.159 , pp. 245-255
    • Rak, J.W.1    Hegmann, E.J.2    Lu, C.3    Kerbel, R.S.4
  • 108
    • 0027755221 scopus 로고
    • Regressing thin cutaneous malignant melanomas (≤ 1.0 mm) are associated with angiogenesis
    • 108. Barnhill RL, Levy MA. Regressing thin cutaneous malignant melanomas (≤ 1.0 mm) are associated with angiogenesis. Am J Pathol 1993, 143, 99-104.
    • (1993) Am J Pathol , vol.143 , pp. 99-104
    • Barnhill, R.L.1    Levy, M.A.2
  • 109
    • 0018236304 scopus 로고
    • The regressing thin malignant melanoma - A distinctive lesion with metastatic potential
    • 109. Gromet MA, Epstein WL, Blois MS. The regressing thin malignant melanoma - a distinctive lesion with metastatic potential. Cancer 1978, 42, 2282-2292.
    • (1978) Cancer , vol.42 , pp. 2282-2292
    • Gromet, M.A.1    Epstein, W.L.2    Blois, M.S.3
  • 110
    • 0024814687 scopus 로고
    • Model predicting survival in stage I melanoma based on tumor progression
    • 110. Clark WH, Elder DE, Guerry D. Model predicting survival in stage I melanoma based on tumor progression. J Natl Cancer Inst 1989, 81, 1893-1904.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 1893-1904
    • Clark, W.H.1    Elder, D.E.2    Guerry, D.3
  • 111
    • 0026655474 scopus 로고
    • Bcl-2 initiates a new category of oncogenes: Regulators of cell death
    • 111. Korsmeyer SJ. Bcl-2 initiates a new category of oncogenes: regulators of cell death. Blood 1992, 80, 879-886.
    • (1992) Blood , vol.80 , pp. 879-886
    • Korsmeyer, S.J.1
  • 112
    • 0028815882 scopus 로고
    • Regulation of apoptosis in normal and malignant ovarian epithelial cells by transforming growth factor β
    • 112. Havrilesky LJ, Hurteau JA, Whitaker RS. Regulation of apoptosis in normal and malignant ovarian epithelial cells by transforming growth factor β. Cancer Res 1995, 55, 944-948.
    • (1995) Cancer Res , vol.55 , pp. 944-948
    • Havrilesky, L.J.1    Hurteau, J.A.2    Whitaker, R.S.3
  • 113
    • 0028225087 scopus 로고
    • Old cells never die, they just apoptose
    • 113. Evan GI. Old cells never die, they just apoptose. Trends Cell Biol 1994, 4, 191-192.
    • (1994) Trends Cell Biol , vol.4 , pp. 191-192
    • Evan, G.I.1
  • 114
    • 0029916820 scopus 로고    scopus 로고
    • Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle
    • 114. Boudreau N, Werb Z, Bissell MJ. Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle. Proc Natl Acad Sci USA 1996, 93, 3509-3513.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3509-3513
    • Boudreau, N.1    Werb, Z.2    Bissell, M.J.3
  • 115
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • 115. Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996, 86, 353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 116
    • 0028941001 scopus 로고
    • Vascular endothelial growth factor in human glioma cell lines: Induced secretion by EGF, PDGF-BB, and bFGF
    • 116. Tsai J-C, Goldman CK, Gillespie GY. Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF. J Neurosurg 1995, 82, 864-873.
    • (1995) J Neurosurg , vol.82 , pp. 864-873
    • Tsai, J.-C.1    Goldman, C.K.2    Gillespie, G.Y.3
  • 117
    • 0029045246 scopus 로고
    • Regulation of vascular endothelial growth fctor expression in cultured keratinocytes
    • 117. Frank S, Hubner G, Breier G, Longaker MT, Greenhalgh DG, Werner S. Regulation of vascular endothelial growth fctor expression in cultured keratinocytes. J Biol Chem 1995, 270, 12607-12613.
    • (1995) J Biol Chem , vol.270 , pp. 12607-12613
    • Frank, S.1    Hubner, G.2    Breier, G.3    Longaker, M.T.4    Greenhalgh, D.G.5    Werner, S.6
  • 118
    • 0029670093 scopus 로고    scopus 로고
    • Cooperative effect of TNFα, bFGF, and VEGF on the formation of tubular structures of human microvascular endothelial cells in a fibrin matrix. Role of urokinase activity
    • 118. Koolwijk P, van Erck MGM, de Vree WJA. Cooperative effect of TNFα, bFGF, and VEGF on the formation of tubular structures of human microvascular endothelial cells in a fibrin matrix. Role of urokinase activity. J Cell Biol 1996, 132, 1177-1188.
    • (1996) J Cell Biol , vol.132 , pp. 1177-1188
    • Koolwijk, P.1    Van Erck, M.G.M.2    De Vree, W.J.A.3
  • 119
    • 0029166443 scopus 로고
    • Regulation of the expression of VEGF/VPS and its receptors: Role in tumor angiogenesis
    • 119. Kolch W, Martiny-Brown G, Kieser A, Marni D. Regulation of the expression of VEGF/VPS and its receptors: role in tumor angiogenesis. Breast Cancer Res Treat 1995, 36, 139-155.
    • (1995) Breast Cancer Res Treat , vol.36 , pp. 139-155
    • Kolch, W.1    Martiny-Brown, G.2    Kieser, A.3    Marni, D.4
  • 120
    • 0028060380 scopus 로고
    • Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
    • 120. Dameron KM, Volpert OV, Tainsky MA, Bouck N. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 1994, 265, 1582-1584.
    • (1994) Science , vol.265 , pp. 1582-1584
    • Dameron, K.M.1    Volpert, O.V.2    Tainsky, M.A.3    Bouck, N.4
  • 121
    • 0028929991 scopus 로고
    • Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas
    • 121. Wizigmann-Voos S, Breier G, Risau W, Plate KH. Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas. Cancer Res 1995, 55, 1358-1364.
    • (1995) Cancer Res , vol.55 , pp. 1358-1364
    • Wizigmann-Voos, S.1    Breier, G.2    Risau, W.3    Plate, K.H.4
  • 122
    • 0029920054 scopus 로고    scopus 로고
    • Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein
    • 122. Siemeister G, Weindel K, Mohrs K, Barleon B, Martiny-Baron G, Marme D. Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein. Cancer Res 1996, 56, 2299-2301.
    • (1996) Cancer Res , vol.56 , pp. 2299-2301
    • Siemeister, G.1    Weindel, K.2    Mohrs, K.3    Barleon, B.4    Martiny-Baron, G.5    Marme, D.6
  • 123
    • 0023139994 scopus 로고
    • Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth
    • 123. Schweigerer L, Neufeld G, Friedman J, Abraham JA, Fiddes JC, Gospodarowicz D. Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth. Nature 1987, 325, 257-259.
    • (1987) Nature , vol.325 , pp. 257-259
    • Schweigerer, L.1    Neufeld, G.2    Friedman, J.3    Abraham, J.A.4    Fiddes, J.C.5    Gospodarowicz, D.6
  • 124
    • 0028785350 scopus 로고
    • Possible participation of autocrine and paracrine vascular endothelial growth factors in hypoxia-induced proliferation of endothelial cells and pericytes
    • 124. Nomura M, Yamagishi S, Harada S. Possible participation of autocrine and paracrine vascular endothelial growth factors in hypoxia-induced proliferation of endothelial cells and pericytes. J Biol Chem 1995, 270, 28316-28324.
    • (1995) J Biol Chem , vol.270 , pp. 28316-28324
    • Nomura, M.1    Yamagishi, S.2    Harada, S.3
  • 125
    • 0025186452 scopus 로고
    • Extension of the life-span of human endothelial cells by an interleukin-1α antisense oligomer
    • 125. Maier JAM, Voulalas P, Roeder D, Maciag T. Extension of the life-span of human endothelial cells by an interleukin-1α antisense oligomer. Science 1990, 249, 1570-1574.
    • (1990) Science , vol.249 , pp. 1570-1574
    • Maier, J.A.M.1    Voulalas, P.2    Roeder, D.3    Maciag, T.4
  • 126
    • 0024523417 scopus 로고
    • Interleukin-6 gene expression in human endothelial cells RNA start sites, multiple IL-6 proteins and inhibition of proliferation
    • 126. May LT, Torcia G, Cozzolino F. Interleukin-6 gene expression in human endothelial cells RNA start sites, multiple IL-6 proteins and inhibition of proliferation. Biochem Biophys Res Commun 1989, 159, 991-997.
    • (1989) Biochem Biophys Res Commun , vol.159 , pp. 991-997
    • May, L.T.1    Torcia, G.2    Cozzolino, F.3
  • 127
    • 0026782385 scopus 로고
    • IL-6 increases endothelial permeability in vitro
    • 127. Maruo N, Morita I, Shirao M, Murota S. IL-6 increases endothelial permeability in vitro. Endocrinology 1992, 131, 710-714.
    • (1992) Endocrinology , vol.131 , pp. 710-714
    • Maruo, N.1    Morita, I.2    Shirao, M.3    Murota, S.4
  • 128
    • 0027097806 scopus 로고
    • Interleukin-8 as a macrophage-derived mediator of angiogenesis
    • 128. Koch AE, Polverini PJ, Kunkel SL. Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science 1992, 258, 1798-1801.
    • (1992) Science , vol.258 , pp. 1798-1801
    • Koch, A.E.1    Polverini, P.J.2    Kunkel, S.L.3
  • 129
    • 0027528783 scopus 로고
    • Scatter factor induces blood vessel formation in vivo
    • 129. Grant D, Kleinman H, Goldberg S. Scatter factor induces blood vessel formation in vivo. Proc Natl Acad Sci USA 1993, 90, 1937-1941.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 1937-1941
    • Grant, D.1    Kleinman, H.2    Goldberg, S.3
  • 130
    • 0021183329 scopus 로고
    • Cultured endothelial cells produce multiple growth factors for connective tissue cells
    • 130. DiCorleto PE. Cultured endothelial cells produce multiple growth factors for connective tissue cells. Exp Cell Res 1984, 153, 167-172.
    • (1984) Exp Cell Res , vol.153 , pp. 167-172
    • DiCorleto, P.E.1
  • 131
    • 0026055366 scopus 로고
    • Connective tissue growth factor: A cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10
    • 131. Bradham DM, Igarashi A, Potter RL, Grotendorst GR. Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J Cell Biol 1991, 114, 1285-1294.
    • (1991) J Cell Biol , vol.114 , pp. 1285-1294
    • Bradham, D.M.1    Igarashi, A.2    Potter, R.L.3    Grotendorst, G.R.4
  • 132
    • 0001772964 scopus 로고
    • Growth factor production by endothelial cells
    • Ryan US, ed. Boca Raton, CRC Press Inc.
    • 132. DiCorleto PE, Fox PL. Growth factor production by endothelial cells. In Ryan US, ed. Endothelial Cells. Boca Raton, CRC Press Inc., 1990, 51-61.
    • (1990) Endothelial Cells , pp. 51-61
    • DiCorleto, P.E.1    Fox, P.L.2
  • 133
    • 0019829625 scopus 로고
    • Cultured endothelial cells produce a heparin like inhibitor of smooth muscle cell growth
    • 133. Castellot JJ Jr, Addonizio ML, Rosenberg R, Karnovsky MJ. Cultured endothelial cells produce a heparin like inhibitor of smooth muscle cell growth. J Cell Biol 1981, 90, 372-379.
    • (1981) J Cell Biol , vol.90 , pp. 372-379
    • Castellot J.J., Jr.1    Addonizio, M.L.2    Rosenberg, R.3    Karnovsky, M.J.4
  • 134
    • 0026078863 scopus 로고
    • Interactions of cultured endothelial cells with TGFbeta, bFGF, PDGF, and IFG-I
    • 134. Boes M, Dake BL, Bar RS. Interactions of cultured endothelial cells with TGFbeta, bFGF, PDGF, and IFG-I. Life Sci 1991, 48, 811-821.
    • (1991) Life Sci , vol.48 , pp. 811-821
    • Boes, M.1    Dake, B.L.2    Bar, R.S.3
  • 135
    • 0026730305 scopus 로고
    • Tumor necrosis factor increases transcription of the heparin-binding epidermal growth factor-like gene in vascular endothelial cells
    • 135. Yoshizumi M, Kourembanas S, Temizer DH, Cambria RP, Quertermous T, Lee ME. Tumor necrosis factor increases transcription of the heparin-binding epidermal growth factor-like gene in vascular endothelial cells. J Biol Chem 1992, 267, 9467-9469.
    • (1992) J Biol Chem , vol.267 , pp. 9467-9469
    • Yoshizumi, M.1    Kourembanas, S.2    Temizer, D.H.3    Cambria, R.P.4    Quertermous, T.5    Lee, M.E.6
  • 136
    • 0019134921 scopus 로고
    • Vascular endothelium as a regulator of granulopoiesis: Production of colony-stimulating activity by cultured human endothelial cells
    • 136. Quesenberry PJ, Gimbrone MA Jr. Vascular endothelium as a regulator of granulopoiesis: production of colony-stimulating activity by cultured human endothelial cells. Blood 1980, 56, 1060-1067.
    • (1980) Blood , vol.56 , pp. 1060-1067
    • Quesenberry, P.J.1    Gimbrone M.A., Jr.2
  • 137
    • 0021802850 scopus 로고
    • Expression of I-region-associated antigen (Ia) and interleukin 1 by subcultured human endothelial cells
    • 137. Wagner CR, Vetto RM, Burger DR. Expression of I-region-associated antigen (Ia) and interleukin 1 by subcultured human endothelial cells. Cell Immun 1985, 93, 91-104.
    • (1985) Cell Immun , vol.93 , pp. 91-104
    • Wagner, C.R.1    Vetto, R.M.2    Burger, D.R.3
  • 138
    • 0026909819 scopus 로고
    • Growth regulation of vascular cells by cytokines
    • 138. Oka S, Mitsui Y. Growth regulation of vascular cells by cytokines. Nippon Rinsho 1992, 50, 1748-1755.
    • (1992) Nippon Rinsho , vol.50 , pp. 1748-1755
    • Oka, S.1    Mitsui, Y.2
  • 139
    • 0026055091 scopus 로고
    • Murine endothelioma cell lines tranformed by polyoma middle T oncogene as a target for and producers of cytokines
    • 139. Bussolino F, De Rossi M, Sica A. Murine endothelioma cell lines tranformed by polyoma middle T oncogene as a target for and producers of cytokines. J Immunol 1991, 147, 2122-2129.
    • (1991) J Immunol , vol.147 , pp. 2122-2129
    • Bussolino, F.1    De Rossi, M.2    Sica, A.3
  • 140
    • 0026166006 scopus 로고
    • Expression of leukemia inhibitory factor is regulated in human mesenchymal cells
    • 140. Lubbert M, Mantovani L, Lindemann A, Mertelsmann R, Herrmann F. Expression of leukemia inhibitory factor is regulated in human mesenchymal cells. Leukemia 1991, 5, 361-365.
    • (1991) Leukemia , vol.5 , pp. 361-365
    • Lubbert, M.1    Mantovani, L.2    Lindemann, A.3    Mertelsmann, R.4    Herrmann, F.5
  • 141
    • 0023183271 scopus 로고
    • Interleukin 1 stimulates human endothelial cells to produce granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor
    • 141. Broudy VC, Kaushansky K, Harlan JM, Adamson JW. Interleukin 1 stimulates human endothelial cells to produce granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor. J Immunol 1987, 139, 464-468.
    • (1987) J Immunol , vol.139 , pp. 464-468
    • Broudy, V.C.1    Kaushansky, K.2    Harlan, J.M.3    Adamson, J.W.4
  • 142
    • 0029043048 scopus 로고
    • Nitric oxide inhibits macrophage-colony stimulating factor gene transcription in vascular endothelial cells
    • 142. Peng HB, Rajavashisth TB, Libby P, Liao JK. Nitric oxide inhibits macrophage-colony stimulating factor gene transcription in vascular endothelial cells. J Biol Chem 1995, 270, 17050-17055.
    • (1995) J Biol Chem , vol.270 , pp. 17050-17055
    • Peng, H.B.1    Rajavashisth, T.B.2    Libby, P.3    Liao, J.K.4
  • 143
    • 0023870783 scopus 로고
    • Molecular endothelial cells and granulopoiesis: Interleukin-1 stimulates release of G-CSF and GM-CSF
    • 143. Zsebo KM, Yuschenkoff VN, Schiffer S. Molecular endothelial cells and granulopoiesis: interleukin-1 stimulates release of G-CSF and GM-CSF. Blood 1988, 71, 99-103.
    • (1988) Blood , vol.71 , pp. 99-103
    • Zsebo, K.M.1    Yuschenkoff, V.N.2    Schiffer, S.3
  • 144
    • 0028131536 scopus 로고
    • Regulation of interleukin-11 protein and mRNA expression in neonatal and adult fibroblasts and endothelial cells
    • 144. Suen Y, Chang M, Lee SM, Buzby JS, Cairo MS. Regulation of interleukin-11 protein and mRNA expression in neonatal and adult fibroblasts and endothelial cells. Blood 1994, 84, 4125-4134.
    • (1994) Blood , vol.84 , pp. 4125-4134
    • Suen, Y.1    Chang, M.2    Lee, S.M.3    Buzby, J.S.4    Cairo, M.S.5
  • 145
    • 0024452557 scopus 로고
    • Expression and secretion of gro/MGSA by stimulated human endothelial cells
    • 145. Wen D, Rowland A, Derynck R. Expression and secretion of gro/MGSA by stimulated human endothelial cells. EMBO J 1989, 8, 1761-1766.
    • (1989) EMBO J , vol.8 , pp. 1761-1766
    • Wen, D.1    Rowland, A.2    Derynck, R.3
  • 146
    • 0027393336 scopus 로고
    • Role of microvascular endothelial cells in inflammation
    • 146. Swerlick RA, Lawley TJ. Role of microvascular endothelial cells in inflammation. J Invest Dermatol 1993, 100, 111S-115S.
    • (1993) J Invest Dermatol , vol.100
    • Swerlick, R.A.1    Lawley, T.J.2
  • 147
    • 0026461974 scopus 로고
    • Differential stimulation of the growth of lung-metastasizing tumor cells by lung (paracrine) growth factors: Identification of transferrin-like mitogens in lung tissue-conditioned medium
    • 147. Nicolson GL, Cavanaugh PG, Inoue T. Differential stimulation of the growth of lung-metastasizing tumor cells by lung (paracrine) growth factors: identification of transferrin-like mitogens in lung tissue-conditioned medium. J Natl Cancer Inst Monographs 1992, 13, 153-161.
    • (1992) J Natl Cancer Inst Monographs , vol.13 , pp. 153-161
    • Nicolson, G.L.1    Cavanaugh, P.G.2    Inoue, T.3
  • 148
    • 0027818475 scopus 로고
    • A paracrine migration-stimulating factor for metastatic tumor cells secreted by mouse hepatic sinusoidal endothelial cells: Identification as complement component C3b
    • 148. Hamada J, Cavanaugh PG, Miki K, Nicolson GL. A paracrine migration-stimulating factor for metastatic tumor cells secreted by mouse hepatic sinusoidal endothelial cells: identification as complement component C3b. Cancer Res 1993, 53, 4418-4423.
    • (1993) Cancer Res , vol.53 , pp. 4418-4423
    • Hamada, J.1    Cavanaugh, P.G.2    Miki, K.3    Nicolson, G.L.4
  • 149
    • 0029681850 scopus 로고    scopus 로고
    • Oncogenic transformation and hypoxia synergistically act to modulate vascular endothelial growth factor expression
    • 149. Mazure NM, Chen EY, Yeh P, Laderoute KR, Giaccia AJ. Oncogenic transformation and hypoxia synergistically act to modulate vascular endothelial growth factor expression. Cancer Res 1996, 56, 3436-3440.
    • (1996) Cancer Res , vol.56 , pp. 3436-3440
    • Mazure, N.M.1    Chen, E.Y.2    Yeh, P.3    Laderoute, K.R.4    Giaccia, A.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.