Structural analysis of ligand binding and catalysis in chorismate lyase

Archives of Biochemistry and Biophysics

Volumn 445, Issue 1, 2006, Pages 72-80

  Smith, Natasha ^a   Roitberg, Adrian E ^b   Rivera, Eva ^b   Howard, Andrew ^c   Holden, Marcia J ^d   Mayhew, Martin ^e   Kaistha, Salita ^f   Gallagher, D T ^d  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c ILLINOIS INSTITUTE OF TECHNOLOGY   (United States)

^d NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^e Biocatalytics Inc ^*  (United States)

^f URSINUS COLLEGE   (United States)

Author keywords

Crystal structure; Dynamic mechanism; Hydroxybenzoate; Product inhibition; X ray diffraction

Indexed keywords

CHORISMATE LYASE; ENZYME INHIBITOR; LIGAND; LYASE; UNCLASSIFIED DRUG; VANILLIC ACID;

ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE; KINETICS; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULE; MUTANT; MUTATION; NONHUMAN; PRIORITY JOURNAL; SIMULATION;

BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; LIGANDS; MODELS, MOLECULAR; MUTATION; OXO-ACID-LYASES; PARABENS; PROTEIN CONFORMATION;

ESCHERICHIA COLI;

EID: 29244450154     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2005.10.026     Document Type: Article

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