The crystal structure of chorismate lyase shows a new fold and a tightly retained product

Proteins: Structure, Function and Genetics

Volumn 44, Issue 3, 2001, Pages 304-311

  Travis Gallagher, D ^a,b   Mayhew, Martin ^a,b   Holden, Marcia J ^a,b   Howard, Andrew ^a,b   Kim, Kyung Jin ^a,b   Vilker, Vincent L ^a,b  

^a NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^b Illinois Institute of Technology   (United States)

Author keywords

Diffraction; Folding; Hydroxybenzoate; Product inhibition; Topology; Ubiquinone

Indexed keywords

CHORISMIC ACID; HELIX LOOP HELIX PROTEIN; HYDROXYBENZOIC ACID; LYASE; UBIQUINONE;

AMINO ACID SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DIFFRACTION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROPHOBICITY; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CRYSTALLIZATION; ESCHERICHIA COLI; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; OXO-ACID-LYASES; PROTEIN CONFORMATION; PROTEIN FOLDING; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0035882556     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.1095     Document Type: Article

References (27)

1. Cloning and sequencing of Escherichia coli ubiC and purification of chorismate lyase
2. Formation of 4-hydroxybenzoate in Escherichia coli: Characterization of the ubiC gene and its encoded enzyme chorismate pyruvate-lyase
3. Thermodynamics of the conversion of chorismate to prephenate: Experimental results and theoretical predictions
4. Thermodynamic and quantum chemical study of the conversion of chorismate to pyruvate and 4-hydroxybenzoate
5. The crystal structure of anthranilate synthase from Sulfolobus sulfataricus: Functional implications
6. Mechanisms of catalysis and allosteric regulation of yeast chorismate mutase from crystal structures
7. The 1.3 Å resolution structure of the Bacillus subtilis chorismate mutase catalytic homotrimer
8. Three-dimensional structure of 4-amino-4-deoxychorismate lyase from E. coli
9. Crystallization and 1.1-A diffraction of chorismate lyase from Escherichia coli
10. Data processing in macromolecular crystallography
11. PHASES-95: A program package for processing and analyzing diffraction data from macromolecules
12. AmoRe: An automated package for molecular replacement
13. Crystallography and NMR system (CNS): A new software system for macromolecular structure determination
14. PROCHECK: A program to check the stereochemical quality of protein structures
15. Dictionary of protein secondary structure: Pattern recognition of hydrogen-bonded and geometrical features
16. Mapping the protein universe
17. Threading a database of protein cores
18. Protein structure alignment by incremental combinatorial extension (CE) of the optimal path
19. The beta bulge: A common small unit of nonrepetitive protein structure
20. SCOP: A structural classification of proteins database for the investigation of sequences and structures
21. The mobile flavin of 4-OH benzoate hydroxylase
22. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
23. A fast algorithm for rendering space-filling molecular pictures
24. Raster3D version 2.0 - A program for photorealistic molecular graphics