Concurrence of histologic features of steatohepatitis with other forms of chronic liver disease

Modern Pathology

Volumn 16, Issue 1, 2003, Pages 49-56

  Brunt, Elizabeth M ^a,c   Ramrakhiani, Sunil ^b   Cordes, Barry G ^a   Neuschwander Tetri, Brent A ^b   Janney, Christine G ^a   Bacon, Bruce R ^b   Di Bisceglie, Adrian M ^b  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b S LOUIS UNIV HLTH SCIENCES CENTER   (United States)

^c SAINT LOUIS UNIVERSITY HOSPITAL   (United States)

Author keywords

Clinical correlations; Concurrence with chronic liver disease; Steatohepatitis

Indexed keywords

ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CHRONIC LIVER DISEASE; CLINICAL FEATURE; DIABETES MELLITUS; HEPATITIS; HEPATITIS C; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER BIOPSY; LIVER FIBROSIS; MAJOR CLINICAL STUDY; OBESITY; PRIORITY JOURNAL; STEATOHEPATITIS;

ADULT; AGED; ALCOHOLISM; BIOPSY, NEEDLE; COMORBIDITY; DIABETES COMPLICATIONS; DIABETES MELLITUS; FATTY LIVER; FEMALE; HEPATITIS; HEPATITIS C; HOSPITALS, UNIVERSITY; HUMANS; MALE; MIDDLE AGED; MISSOURI; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 12244284662     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.MP.0000042420.21088.C7     Document Type: Article

References (55)

1. Baldridge AD, Perezatayde AR, Graemecook F, Higgins L, Lavine JE. Idiopathic steatohepatitis in childhood - a multicenter retrospective study. J Pediatr 1995;127:700-4.
2. Brunt EM. Nonalcoholic steatohepatitis: definition and pathology. Semin Liver Dis 2001;21:3-16.
3. Cortez-Pinto H, Chatham J, Chacko VP, Arnold C, Rashid A, Diehl AM. Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis: a pilot study. JAMA 1999;282: 1659-64.
4. Ludwig J, Viggiano TR, McGill DB, Oh BJ. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980;55:434-8.
5. Burt AD, Mutton A, Day CP. Diagnosis and interpretation of steatosis and steatohepatitis. Semin Diagn Pathol 1998;15: 246-58.
6. Ludwig J, McGill DB, Lindor KD. Nonalcoholic steatohepatitis. J Gastroenterol Hepatol 1997;12:398-403.
7. Ishak KG. Chronic hepatitis: morphology and nomenclature. Mod Pathol 1994;7:690-713.
8. Cacciola I, Pollicino T, Squadrito G, Cerenzia G, Orlando ME, Raimondo G. Occult hepatitis B infection in patients with chronic hepatitis C liver disease. N Engl J Med 1999;341:22-6.
9. Fong TL, Di Bisceglie AM, Waggoner JG, Banks SM, Hoofnagle JH. The significance of antibody to hepatitis C virus in patients with chronic hepatitis B. Hepatology 1991; 14:64-7.
10. Zarski JP, Bohn B, Bastie A, Pawlotsky JM, Baud M, Bostbezequx F, et al. Characteristics of patients with dual infection by hepatitis B and C viruses. J Hepatol 1998;28:27-33.
11. Pessione F, Degos F, Marcellin P, Duchatelle V, Njapoum C, Martinotpeignoux M, et al. Effect of alcohol consumption on serum hepatitis C virus RNA and histological lesions in chronic hepatitis C. Hepatology 1998;27:1717-22.
12. Degos F. Hepatitis C and alcohol. J Hepatol 1999;31:113-8.
13. Bacon BR, Olynyk JK, Brunt EM, Britton RS, Wolff RK. HFE genotype in patients with hemochromatosis and other liver diseases. Ann Intern Med 1999;130:953-62.
14. Bonkovsky HL, Obando JV. Role of HFE gene mutations in liver diseases other than hereditary hemochromatosis. Curr Gastroenterol Rep 1999;1:30-7.
15. George DK, Powell LW, Losowsky MS. The haemochromatosis gene: a co-factor for chronic liver diseases? J Gastroenterol Hepatol 1999;14:745-9.
16. Brunt EM, Tavill AS, Bacon BR. A 49-year-old man with alpha 1-antitrypsin deficiency and abnormal iron study results. Semin Liver Dis 1996;16:97-101.
17. Brunt EM, Janney CG, Di Bisceglie AM, Neuschwander-Tetri BA, Bacon BR. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 1999;94:2467-74.
18. Scheuer PJ. Classification of chronic viral hepatitis: a need for reassessment. J Hepatol 1991;13:372-4.
19. Brunt EM. Liver biopsy interpretation for the gastroenterologist. Curr Gastroenterol Rep 2000;2:27-32.
20. James O, Day C. Non-alcoholic steatohepatitis: another disease of affluence. Lancet 1999;353:1634-6.
21. Neuschwander-Tetri BA, Bacon BR. Nonalcoholic steatohepatitis. Med Clin North Am 1996;80:1147-66.
22. Diehl AM, Goodman Z, Ishak KG. Alcohollike liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury. Gastroenterology 1988;95:1056-62.
23. Lee RG. Nonalcoholic steatohepatitis: a study of 49 patients. Hum Pathol 1989;20:594-8.
24. Itoh S, Yougel T, Kawagoe K. Comparison between nonalcoholic steatohepatitis and alcoholic hepatitis. Am J Gastroenterol 1987;82:650-4.
25. Matteoni CA, Younossi ZM, Gramlich T, Boparai N, Liu YC, McCullough AJ. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999; 116:1413-9.
26. Gerber MA, Krawczynski K, Alter MJ, Sampliner RE, Margolis HS. Histopathology of community acquired chronic hepatitis C. The Sentinel Counties Chronic Non-A, Non-B Hepatitis Study Team. Mod Pathol 1992;5:483-6.
27. Scheuer PJ, Ashrafzadeh P, Sherlock S, Brown D, Dusheiko GM. The pathology of hepatitis C. Hepatology 1992;15:567-71.
28. Lefkowitch JH, Schiff ER, Davis GL, Perrillo RP, Lindsay K, Bodenheimer HC, et al. Pathological diagnosis of chronic hepatitis C: a multicenter comparative study with chronic hepatitis B. Gastroenterology 1993;104:595-603.
29. Badizadegan K, Jonas MM, Ott MJ, Nelson SP, Perezatayde AR. Histopathology of the liver in children with chronic hepatitis C viral infection. Hepatology 1998;28:1416-23.
30. Adinolfi LE, Utili R, Andreana A, Tripodi MF, Rosario P, Mormone G, et al. Relationship between genotypes of hepatitis C virus and histopathological manifestations in chronic hepatitis C patients. Eur J Gastroenterol Hepatol 2000;12:299-304.
31. Adinolfi LE, Gambardella M, Andreana A, Tripodi MF, Utili R, Ruggiero G. Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity. Hepatology 2001;33:1358-64.
32. Rubbia-Brandt L, Quadri R, Abid K, Giostra E, Male PJ, Mentha G, et al. Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3. J Hepatol 2000;33:106-15.
33. Mihm S, Fayyazi A, Hartmann H, Ramadori G. Analysis of histopathological manifestations of chronic hepatitis C virus infection with respect to virus genotype. Hepatology 1997; 25:735-9.
34. Hourigan LF, Macdonald GA, Purdie D, Whitehall VH, Shorthouse C, Clouston A, et al. Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis. Hepatology 1999;29:1215-9.
35. Fiore G, Fera G, Napoli N, Vella F, Schiraldi O. Liver steatosis and chronic hepatitis C - a spurious association. Eur J Gastroenterol Hepatol 1996;8:125-9.
36. Moriya K, Yotsuyanagi H, Shintani Y, Fujie H, Ishibashi K, Matsuura Y, et al. Hepatitis C virus core protein induces hepatic steatosis in transgenic mice. J Gen Virol 1997;78:1527-31.
37. Tankurt E, Biberoglu S, Ellidokuz E, Hekimsoy Z, Akpinar H, Comlekci A, et al. Hyperinsulinemia and insulin resistance in non-alcoholic steatohepatitis. J Hepatol 1999;31:963.
38. Sheth SG, Gordon FD, Chopra S. Nonalcoholic steatohepatitis. Ann Intern Med 1997;126:137-45.
39. Chitturi S, Farrell GC. Etiopathogenesis of nonalcoholic steatohepatitis. Semin Liver Dis 2001;21:27-41.
40. Day CP, James OF. Steatohepatitis: a tale of two "hits"? Gastroenterology 1998;114:842-5.
41. Sanyal AJ, Campbell-Sargent C, Mirshahi F, Rizzo WB, Contos MJ, Sterling RK, et al. Nonalcoholic steatohepatitis: association of insulin resistance and mitochondrial abnormalities. Gastroenterology 2001;120:1183-92.
42. Marceau P, Biron S, Hould FS, Marceau S, Simard S, Thung SN, et al. Liver pathology and the metabolic syndrome X in severe obesity. J Clin Endocrinol Metab 1999;84:1513-7.
43. Marchesini G, Brizi M, Morselli-Labate AM, Bianchi G, Bugianesi E, McCullough AJ, et al. Association of nonalcoholic fatty liver disease with insulin resistance. Am J Med 1999;107:450-5.
44. Mehta SH, Brancati FL, Sulkowski MS, Strathdee SA, Szklo M, Thomas DL. Prevalence of type 2 diabetes mellitus among persons with hepatitis C virus infection in the United States. Hepatology 2001;33:1554.
45. Falchuk KR, Fiske SC, Haggitt RC, Federman M, Trey C. Pericentral hepatic fibrosis and intracellular hyalin in diabetes mellitus. Gastroenterology 1980;78:535-41.
46. French SWN, J, Shitabata P, et al. Pathology of alcoholic liver disease. Semin Liver Dis 1993;13:154.
47. Kyriacou E, Simmonds P, Miller EK, Bouchier IAD, Hayes PC, Harrison DJ. Liver biopsy findings in patients with alcoholic liver disease complicated by chronic hepatitis C virus infection. Eur J Gastroenterol Hepatol 1995;7:331-4.
48. Rogers DW, Lee CH, Pound DC, Kumar S, Cummings OW, Lumeng L. Hepatitis C virus does not cause nonalcoholic steatohepatitis. Dig Dis Sci 1992;37:1644-7.
49. Uchimura Y, Sata M, Kage M, Abe H, Tanikawa K. A histopathological study of alcoholics with chronic HCV infection - comparison with chronic hepatitis C and alcoholic liver disease. Liver 1995;15:300-6.
50. Clouston AD, Jonsson JR, Purdie DM, Macdonald GA, Pandeya N, Shorthouse C, et al. Steatosis and chronic hepatitis C: analysis of fibrosis and stellate cell activation. J Hepatol 2001;34:314-20.
51. McCullough AJ, Falck-Ytter Y. Body composition and hepatic steatosis as precursors for fibrotic liver disease. Hepatology 1999;29:1328-30.
52. Wong VS, Wight DGD, Palmer CR, Alexander GJM. Fibrosis and other histological features in chronic hepatitis C virus infection - a statistical model. J Clin Pathol 1996;49:465-9.
53. Lauer GM, Walker BD. Hepatitis C virus infection. N Engl J Med 2001;345:41-52.
54. Falck-Ytter Y, Younossi ZM, Marchesini G, McCullough AJ. Clinical features and natural history of nonalcoholic steatosis syndromes. Semin Liver Dis 2001;21:17-26.
55. Caldwell SH, Oelsner DH, lezzoni JC, Hespenheide EE, Battle EH, Driscoll CJ. Cryptogenic cirrhosis: clinical characterization and risk factors for underlying disease. Hepatology 1999;29:664-9.