Early induction of leukemia inhibitor factor (LIF) in acute HIV-1 infection

AIDS

Volumn 20, Issue 1, 2006, Pages 11-19

  Tjernlund, Annelie ^a   Barqasho, Babilonia ^a   Nowak, Piotr ^a   Kinloch, Sabine ^b   Thorborn, Daren ^c   Perrin, Luc ^d   Sönnerborg, Anders ^a   Walther Jallow, Lilian ^a   Andersson, Jan ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b ROYAL FREE HOSPITAL   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

^d GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

ELISA; HIV; LIF; PHI; Plasma; sgp130

Indexed keywords

GLYCOPROTEIN GP 130; LEUKEMIA INHIBITORY FACTOR; VIRUS RNA;

ABNORMALLY HIGH SUBSTRATE CONCENTRATION IN BLOOD; ADULT; ARTICLE; BLOOD SAMPLING; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; EPSTEIN BARR VIRUS; FEMALE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION CONTROL; INFLAMMATION; MALE; PLASMA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN INDUCTION; SERODIAGNOSIS; SIGNAL TRANSDUCTION; SOLUBILITY; TREATMENT WITHDRAWAL; VIREMIA; VIRUS INFECTION; VIRUS LOAD; VIRUS REPLICATION; VIRUS TRANSMISSION;

EID: 29144510559     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aids.0000198082.16960.94     Document Type: Article

References (26)

1. Kedzierska K, Crowe SM. Cytokines and HIV-1: interactions and clinical implications. Antivir Chem Chemother 2001; 12:133-150.
2. Auernhammer CJ, Melmed S. Leukemia-inhibitory factor-neuroimmune modulator of endocrine function. Endocr Rev 2000; 21:313-345.
3. Patterson BK, Behbahani H, Kabat WJ, Sullivan Y, O'Gorman MR, Landay A, et al. Leukemia inhibitory factor inhibits HIV-1 replication and is upregulated in placentae from nontransmitting women. J Clin Invest 2001; 107:287-294.
4. Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P. Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells. Science 1995; 270:1811-1815.
5. Tjernlund A, Fleener Z, Behbahani H, Connick E, Sonnerborg A, Brostrom C, et al. Suppression of leukemia inhibitor factor in lymphoid tissue in primary HIV infection: absence of HIV replication in gp130-positive cells. AIDS 2003; 17:1303-1310.
6. Perrin L. Therapeutic vaccination in primary HIV infection, the Quest trial. Vaccine 2002; 20:2004-2006.
7. Kinloch-de Loes S, Hoen B, Smith DE, Autran B, Lampe FC, Phillips AN, et al. Impact of therapeutic immunisation on HIV-1 viremia after discontinuation of antiretroviral therapy initiated during acute infection. J Infect Dis 2005; 192:607-617.
8. Yerly S, Rutschmann OT, Opravil M, Marchal F, Hirschel B, Perrin L. Cell-associated HIV-1 RNA in blood as indicator of virus load in lymph nodes. The Swiss HIV Cohort Study. J Infect Dis 1999; 180:850-853.
9. Yerly S, Kaiser L, Perneger TV, Cone RW, Opravil M, Chave JP, et al. Time of initiation of antiretroviral therapy: impact on HIV-1 viraemia. The Swiss HIV Cohort Study. AIDS 2000; 14:243-249.
10. Taupin JL, Gualde N, Moreau JF. A monoclonal antibody based ELISA for quantitation of human leukaemia inhibitory factor. Cytokine 1997; 9:112-118.
11. Mellors JW, Kingsley LA, Rinaldo CR Jr, Todd JA, Hoo BS, Kokka RP, et al. Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversion. Ann Intern Med 1995; 122:573-579.
12. Lifson JD, Nowak MA, Goldstein S, Rossio JL, Kinter A, Vasquez G, et al. The extent of early viral replication is a critical determinant of the natural history of simian immunodeficiency virus infection. J Virol 1997; 71:9508-9514.
13. Lindback S, Karlsson AC, Mittler J, Blaxhult A, Carlsson M, Briheim G, et al. Viral dynamics in primary HIV-1 infection. Karolinska Institutet Primary HIV Infection Study Group. AIDS 2000; 14:2283-2291.
14. Blattner WA, Ann Oursler K, Cleghorn F, Charurat M, Sill A, Bartholomew C, et al. Rapid clearance of virus after acute HIV-1 infection: correlates of risk of AIDS. J Infect Dis 2004; 189:1793-1801.
15. Giorgi JV, Hultin LE, McKeating JA, Johnson TD, Owens B, Jacobson LP, et al. Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage. J Infect Dis 1999; 179:859-870.
16. Giorgi JV, Lyles RH, Matud JL, Yamashita TE, Mellors JW, Hultin LE, et al. Predictive value of immunologic and virologic markers after long or short duration of HIV-1 infection. J Acquir Immune Defic Syndr 2002; 29:346-355.
17. Fahey JL, Taylor JM, Manna B, Nishanian P, Aziz N, Giorgi JV, et al. Prognostic significance of plasma markers of immune activation, HIV viral load and CD4 T-cell measurements. AIDS 1998; 12:1581-1590.
18. Sabin CA, Devereux H, Phillips AN, Janossy G, Loveday C, Lee CA. Immune markers and viral load after HIV-1 seroconversion as predictors of disease progression in a cohort of haemophilic men. AIDS 1998; 12:1347-1352.
19. Salazar-Gonzalez JF, Martinez-Maza O, Nishanian P, Aziz N, Shen LP, Grosser S, et al. Increased immune activation precedes the inflection point of CD4 T cells and the increased serum virus load in human immunodeficiency virus infection. J Infect Dis 1998; 178:423-430.
20. Chakrabarti LA. The paradox of simian immunodeficiency virus infection in sooty mangabeys: active viral replication without disease progression. Front Biosci 2004; 9:521-539.
21. Modrell B, Liu J, Miller H, Shoyab M. LIF and OM directly interact with a soluble form of gp130, the IL-6 receptor signal transducing subunit. Growth Factors 1994; 11:81-91.
22. Narazaki M, Yasukawa K, Saito T, Ohsugi Y, Fukui H, Koishihara Y, et al. Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130. Blood 1993; 82:1120-1126.
23. Broor S, Kusari AB, Zhang B, Seth P, Richman DD, Carson DA, et al. Stimulation of HIV replication in mononuclear phagocytes by leukemia inhibitory factor. J Acquir Immune Defic Syndr 1994; 7:647-654.
24. Brenchley JM, Schacker TW, Ruff LE, Price DA, Taylor JH, Beilman GJ, et al. CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med 2004; 200:749-759.
25. Li Q, Duan L, Estes JD, Ma ZM, Rourke T, Wang Y, et al. Peak SIV replication in resting memory CD4(+) T cells depletes gut lamina propria CD4(+) T cells. Nature 2005; 192:1269-1271.
26. Mattapallil JJ, Douek DC, Hill B, Nishimura Y, Martin M, Roederer M. Massive infection and loss of memory CD4(+) T cells in multiple tissues during acute SIV infection. Nature 2005; 414:1093-1097.