Rational design of the new antihypertensive I1-receptor ligand 2-(2-biphenyl-2-yl-1-methyl-ethyl)-4,5-dihydro-1H-imidazole

Letters in Drug Design and Discovery

Volumn 2, Issue 8, 2005, Pages 571-578

  Gentili, F ^a   Bousquet, P ^b   Carrieri, A ^c   Feldman, J ^b   Ghelfi, F ^a   Giannella, M ^a   Piergentili, A ^a   Quaglia, W ^a   Vesprini, C ^a   Pigini, M ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c UNIVERSITY OF BARI   (Italy)

Author keywords

Antagonism agonism; Antihypertensive activity; I1 ligands; Molecular superposition

Indexed keywords

2 (2 BIPHENYL 2 YL 1 METHYLETHYL) 4,5 DIHYDRO 1H IMIDAZOLE; ALPHA 2 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIHYPERTENSIVE AGENT; IMIDAZOLE DERIVATIVE; PHENYL GROUP; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CARDIOVASCULAR EFFECT; CHIRALITY; CHO CELL; CONTROLLED STUDY; DRUG DESIGN; DRUG SYNTHESIS; ENANTIOMER; FEMALE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 29044435951     PISSN: 15701808     EISSN: None     Source Type: Journal    
DOI: 10.2174/157018005774717325     Document Type: Article

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