Thermolabile 8-hydroxyguanine DNA glycosylase with low activity in senescence-accelerated mice due to a single-base mutation

Free Radical Biology and Medicine

Volumn 27, Issue 7-8, 1999, Pages 848-854

  Choi, Jeong Yun ^a   Kim, Hun Sik ^b   Kang, Hee Kyoung ^a   Lee, Dong Wook ^c   Choi, Eun Mi ^d   Chung, Myung Hee ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Chungbuk National University College of Medicine   (South Korea)

^c Korea Ginseng Corporation   (South Korea)

^d SolarLight Ltd   (South Korea)

Author keywords

8 hydroxyguanine; Active oxygens; Aging; DNA repair; Free radicals; Mutation; OGG1; SAM

Indexed keywords

8 HYDROXYGUANINE; DNA GLYCOSYLTRANSFERASE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE;

AGING; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RABBIT; SENESCENCE; SOMATIC MUTATION; TEMPERATURE;

AGING; ANIMALS; DNA DAMAGE; DNA REPAIR; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; ENZYME STABILITY; GENE EXPRESSION REGULATION; GUANINE; MICE; MICE, INBRED STRAINS; N-GLYCOSYL HYDROLASES; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE; POINT MUTATION; RECOMBINANT PROTEINS; RNA, MESSENGER; TEMPERATURE;

EID: 0032884691     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(99)00141-0     Document Type: Article

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