Molecular cloning and expression of the functional rat C5a receptor

Molecular Immunology

Volumn 34, Issue 12-13, 1997, Pages 877-886

  Rothermel, Ellen ^a   Zwirner, Jörg ^a   Vogt, Torsten ^a   Rabini, Sabine ^a   Götze, Otto ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

C5a receptor; cDNA cloning; Complement; Rat

Indexed keywords

CALCIUM ION; COMPLEMENT COMPONENT C5A; COMPLEMENT RECEPTOR; COMPLEMENTARY DNA; IODINE 125; MESSENGER RNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CHEMOTAXIS; COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LIGAND BINDING; MACROPHAGE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; BASE SEQUENCE; CALCIUM; CHEMOTAXIS; CLONING, MOLECULAR; COMPLEMENT C5A; DOGS; GENE EXPRESSION; HUMANS; LEUKEMIA, BASOPHILIC, ACUTE; LIGANDS; MACROPHAGES, PERITONEAL; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RATS; RECEPTOR, ANAPHYLATOXIN C5A; RECEPTORS, COMPLEMENT; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA; EUKARYOTA; MURINAE; RODENTIA;

EID: 0031424496     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(97)00104-1     Document Type: Article

References (41)

1. Chenoweth D. E. and Hugli T. E. (1978) Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes. Proc. natn. Acad. Sci. U.S.A. 75, 3943-3947.
2. Chenoweth D. E., Goodman M. G. and Weigle W. O. (1982) Demonstration of a specific receptor for human C5a anaphylatoxin on murine macrophages. J. exp. Med. 156, 68-78.
3. Cui L., Carney D. F. and Hugli T. E. (1994) Primary structure and functional characterization of rat C5a: an anaphylatoxin with unusual high potency. Protein Science 3, 1169-1177.
4. DeMartino J. A., Van Riper G., Siciliano S. J., Molineaux C. J., Konteatis Z. D., Rosen H. and Springer M. S. (1994) The amino terminus of the human C5a receptor is required for high affinity C5a binding and for receptor activation by C5a but not C5a analogs. J. biol. Chem. 269, 14446-14450.
5. DeMartino J. A., Konteatis Z. D., Siciliano S. J., Van Riper G., Underwood D. J., Fischer P. A. and Springer M. S. (1995) Arginine 206 of the C5a receptor is critical for ligand recognition and receptor activation by C-terminal hexapeptide analogs. J. biol. Chem. 270, 15966-15969.
6. Feinberg A. P. and Vogelstein B. (1983) A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Analyt. Biochem. 132, 6-13.
7. Fernandez H. N., Henson P. M., Otani A. and Hugli T. E. (1978) Chemotactic response to human C3a and C5a leukotaxis in vitro and under simulated in vivo conditions. J. Immun. 120, 109-115.
8. Findlay J. B. C. and Pappin D. J. C. (1986) The opsin family of proteins. Biochem. J. 238, 625-642.
9. Gerard N. P. and Gerard C. (1991) The chemotactic receptor for human C5a anaphylatoxin. Nature 349, 614-617.
10. Gerard N. P., Hodges M. K., Drazen J. M., Weller P. F. and Gerard C. (1989) Characterization of a receptor for C5a anaphylatoxin on human eosinophils. J. biol. Chem. 264, 1760-1766.
11. Gerard C., Bao L., Orozco O., Pearson M., Kunz D. and Gerard N. P. (1992) Structural diversity in the extracellular faces of peptidergic G-protein-coupled receptors. Molecular cloning of the mouse C5a anaphylatoxin receptor. J. Immun. 149, 2600-2606.
12. Goldstein I. M. and Weissmann G. (1974) Generation of C5a-derived lysosomal enzyme-releasing activity (C5a) by lysates of leukocyte lysosomes. J. Immun. 113, 1583-1588.
13. Grant J. A., Dupree E., Goldman A. S., Schultz D. R. and Jackson A. L. (1975) Complement-mediated release of histamine from human leukocytes. J. Immun. 114, 1101-1106.
14. Gunning P., Leavitt J., Muscat G., Ng S. Y. and Kedes L. (1987) A human beta-actin expression system directs high-level accumulation of antisense transcripts. Proc. natn. Acad. Sci. U.S.A. 84, 4831-4835.
15. Hagenlocker B. E., Walker B. A. and Ward P. A. (1990) Superoxide responses of immune complex-stimulated rat alveolar macrophages. Intracellular calcium and priming. J. Immun. 144, 3898-3906.
16. Haviland D. L., McCoy R. L., Whitehead W. T., Akama H., Molmenti E. P., Brown A., Haviland J. C., Parks W. C., Perlmutter D. H. and Wetsel R. A. (1995) Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung. J. Immun. 154, 1861-1869.
17. Hespeling U., Püschel G. P., Jungermann K., Götze O., Zwirner J. (1995) Stimulation of glycogen phosphorylase in rat hepatocytes via prostanoid release from Kupffer cells by recombinant rat anaphylatoxin C5a but not by native human C5a in hepatocyte/Kupffer cell co-cultures. FEBS Lett. 372, 108-112.
18. Kozak M. (1987) At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells. J. molec. Biol. 196, 947-950.
19. Kurimoto Y., de Weck A. L. and Dahinden C. A. (1989) Interleukin 3-dependent mediator release in basophils triggered by C5a. J. exp. Med. 170, 467-479.
20. Kyte J. and Doolittle R. F. (1982) A simple method for displaying the hydropathic character of a protein. J. molec. Biol. 157, 105-132.
21. Marder S. R., Chenoweth D. E., Goldstein I. M. and Perez H. D. (1985) Chemotactic responses of human peripheral blood monocytes to the complement-derived peptides C5a and C5a des Arg. J. Immun. 134, 3325-3331.
22. 2+. Biochem. J. 264, 8171-8178.
23. Mery L. and Boulay F. (1993) Evidence that the extracellular N-terminal domain of C5aR contains amino-acid residues crucial for C5a binding. Eur. J. Haemat. 51, 282-287.
24. Mizushima S. and Nagata S. (1990) pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18, 5322.
25. Murphy H. S., Shayman J. A., Till G. O., Mahrougui M., Owens C. B., Ryan U. S. and Ward P. A. (1992) Superoxide responses of endothelial cells to C5a and TNF-alpha: divergent signal transduction pathways. Am. J. Physiol. 263, 51-59.
26. Oppermann M., Raedt U., Hebell T., Schmidt B., Zimmermann B. and Götze O. (1993) Probing the human receptor for C5a anaphylatoxin with site-directed antibodies. J. Immun. 151, 3785-3794.
27. Perret J. J., Raspe E., Vassart G. and Parmentier M. (1992) Cloning and functional expression of the canine anaphylatoxin C5a receptor. Biochem. J. 288, 911-917.
28. Püschel G. P., Oppermann M., Muschol W., Götze O. and Jungermann K., (1989) Increase of glucose and lactate output and decrease of flow by human anaphylatoxin C3a but not C5a in perfused rat liver. FEBS Lett. 243, 83-87.
29. Rothermel E., Rolf O., Götze O. and Zwirner J. (1997) Nucleotide and corrected amino acid sequence of the functional recombinant rat anaphylatoxin C5a. Biochem. Biophys. Acta 1351, 9-12.
30. Sanger F., Nicklen S. and Coulson A. R. (1977) DNA sequencing with chain-terminating inhibitors. Proc. natn. Acad. Sci. U.S.A. 74, 5463-5467.
31. Scheid C. R., Webster R. O., Henson P. M. and Findlay S. R. (1983) Direct effects of complement factor C5a on the contractile state of isolated smooth muscle cells. J. Immun. 130, 1997-1999.
32. Schieferdecker H. L., Rothermel E., Timmermann A., Götze O. and Jungermann K. (1997) Anaphylatoxin C5a receptor mRNA is strongly expressed in Kupffer and stellate cells and weakly in sinusoidal endothelial cells but not in hepatocytes of normal rat liver. FEBS Lett. 406, 305-309.
33. Schorlemmer H. U., Davies P. and Allison A. C. (1976) Ability of activated complement components to induce lysosomal enzyme release from macrophages. Nature 261, 48-49.
34. Schulze M. and Götze O. (1986) A sensitive ELISA for the quantitation of human C5a in blood plasma using a monoclonal antibody. Complement 3, 25-39.
35. Shin H. S., Snyderman R., Friedman E., Mellors A. and Meyer M. (1968) Chemotactic and anaphylatoxic fragments cleaved from the fifth component of guinea pig complement. Science 162, 361-363.
36. Siciliano S. J., Rollins T. E., DeMartino J., Konteatis Z., Malkowitz L., Van Riper G., Bondy S., Rosen H. and Springer M. S. (1994) Two-site binding of C5a by ist receptor: an alternative binding paradigm for G protein-coupled receptors. Proc. natn. Acad. Sci. U.S.A. 91, 1214-1218.
37. Stimler N. P., Brocklehurst W. E., Bloor C. M. and Hugli T. E. (1981) Anaphylatoxin mediated contraction of guinea pig lung strips: a nonhistamine tissue response. J. Immun. 126, 2258-2261.
38. Strader C. D., Sigal I. S. and Dixon R. A. F. (1989) Structural basis of beta-adrenergic receptor function. FASEB J. 3, 1825-1832.
39. Wurst W., Benesch C., Drabent B., Rothermel E., Benecke B. J. and Günther E. (1989) Localization of heat shock protein 70 genes inside the rat major histocompatibility complex close to the class III genes. Immunogenetics 30, 46-49.
40. Yang S., Luo H. Y., Wilson M. A., Wead W. B. and Harris P. D. (1995) Altered microvascular responses to C5a in rat striated muscle during two-kidney, one clip renovascular hypertension. J. Hypertens. 13, 227-233.
41. Zahn S., Zwirner J., Spengler H. P. and Götze O. (1997) Chemoattractant receptors for interleukin-8 and C5a: expression on peripheral blood leukocytes and differential regulation on HL-60 and AML-193 cells by vitamin D3 and all-trans retinoic acid. Eur. J. Immun. 27, 935-940.