Effects of a new C5a receptor antagonist on C5a- and endotoxin-induced neutropenia in the rat

British Journal of Pharmacology

Volumn 126, Issue 3, 1999, Pages 551-554

  Short, Anna ^a   Wong, Allan K ^a   Finch, Angela M ^a   Haaima, Gerald ^a   Shiels, Ian A ^a   Fairlie, David P ^a   Taylor, Stephen M ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

C5a; C5a antagonist; Endotoxic shock; Lipopolysaccharide; Neutropenia

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; COMPLEMENT COMPONENT C5A; COMPLEMENT COMPONENT C5A RECEPTOR; COMPLEMENT COMPONENT C5A RECEPTOR ANTAGONIST; CYCLOPEPTIDE; ENDOTOXIN; PHE [ORN PRO D CYCLOHEXYLALANINE TRP ARG]; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; CONTROLLED STUDY; DOSE RESPONSE; ESCHERICHIA COLI; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; NEUTROPENIA; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIGENS, CD; COMPLEMENT C5A; COMPLEMENT INACTIVATOR PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXINS; FEMALE; HUMANS; LEUKOCYTE COUNT; LIPOPOLYSACCHARIDES; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPENIA; NEUTROPHILS; RATS; RATS, WISTAR; RECEPTOR, ANAPHYLATOXIN C5A; RECEPTORS, COMPLEMENT; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES;

EID: 0033029306     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702338     Document Type: Article

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