Cloning and characterization of the guinea pig C5a anaphylatoxin receptor: Interspecies diversity among the C5a receptors

International Immunology

Volumn 10, Issue 3, 1998, Pages 275-283

  Fukuoka, Yoshihiro ^a,b   Ember, Julia A ^a   Yasui, Akira ^b   Hugli, Tony E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

CD88; cDNA; Complement

Indexed keywords

ANAPHYLATOXIN; CALCIUM ION; COMPLEMENT COMPONENT C5A; COMPLEMENT RECEPTOR; COMPLEMENTARY DNA; MEMBRANE PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; CALCIUM MOBILIZATION; CONTROLLED STUDY; CROSS REACTION; DNA LIBRARY; FIBROBLAST; GENETIC TRANSFECTION; GUINEA PIG; HOST RESISTANCE; L CELL; LIGAND BINDING; MEGAKARYOCYTE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; BASE SEQUENCE; CLONING, MOLECULAR; DOGS; GUINEA PIGS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; RATS; RECEPTOR, ANAPHYLATOXIN C5A; RECEPTORS, COMPLEMENT; SPECIES SPECIFICITY;

EID: 0031914438     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/10.3.275     Document Type: Article

References (46)

1. Okusawa, S., Dinarello, C. A., Yancey, F. B., Endres, S., Lawley, T. J., Frank, M. M., Burke, J. F. and Gelfand, J. A, 1987. C5a induction of human interleukin 1. Synergistic effect with endotoxin or Interferon gamma. J Immunol. 139:2635.
2. Morgan, E. L. 1993. Complement C5a and immunoregulation. In Cruse, J. M. and Lewis, R. E., eds, Complement Today. Complement Profiles Series, vol. 1, p. 56. Karger, Basel.
3. Ember, J. A., Sanderson, S. D., Hugli, T. E. and Morgan, E. L. 1994. Induction of interleukin-8 synthesis from monocytes by human C5a anaphylatoxin. Am. J. Pathol. 144:393.
4. Foreman, K. E., Vaporciyan, A. A., Bonish, B. K., Jones, M. L., Johnson, K. J., Glovsky, M. M., Eddy, S. M. and Ward, P. A. 1994. C5a-induced expression of P-selectin in endothelial cells. J. Clin. Invest. 94:1147.
5. Tonnesen, M. G. 1989. Neutrophil-endothelial cell interactions: mechanisms of neutrophil adherence to vascular endothelium. J. Invest. Dermatol. 93:53S.
6. Rollins, T. E., Siciliano, S., Kobayashi, S., Cianciarulo, D. N., Argudo, V. B., Collier, K. and Springer, M. S. 1991. Purification of the active C5a receptor from human polymorphonuclear leukocytes as a receptor-Gi complex. Proc. Natl Acad. Sci. USA 88:971.
7. Gerard, N. P. and Gerard, C. 1991. The chemotactic receptor for human C5a anaphylatoxin. Nature 349:614.
8. Boulay, F., Mery, L., Tardif, M., Brouchon, L. and Vignais, P. 1991. Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells. Biochemistry 30:2993.
9. Murphy, P. M. and Tiffany, H. L. 1991. Cloning of complementary DNA encoding a functional human interleukin-8 receptor. Science 253:1280.
10. Boulay, F., Tardif, M., Brouchon, L. and Vignais, P. 1990. The human N-formylpeptide receptor. Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors. Biochemistry 29:11123
11. Honda, Z., Nakamura, M., Miki, I., Minami, M., Watanabe, T., Seyama, Y, Okado, H., Toh, H., Ito, K., Miyamoto, T. and Simizu, T. 1991. Cloning by functional expression of platelet-activating factor receptor from guinea pig lung. Nature 349:362.
12. Hopken, U. E., Lu, B., Gerard, N. P. and Gerard, C. 1996. The C5a chemoattractant receptor mediates mucosal defence to infection. Nature 383:86.
13. Morgan, E. L., Ember, J. A., Sanderson, S. D., Scholz, W., Buchner, R., Ye, R. D. and Hugli, T. E. 1993. Anti-C5a receptor antibodies: I. Characterization of neutralizing antibodies specific for a peptide, C5aR(9-29), derived from the predicted amino-terminal sequence of the human C5a receptor. J. Immunol. 151:377.
14. Oppermann, M., Raedt, U., Hebell, T., Schmidt, B., Zimmermann, B. and Götze, O. 1993. Probing the human receptor for C5a anaphylatoxin with site-directed antibodies. Identification of a potential ligand binding site on the NH2-terminal domain. J. Immunol. 151:2785.
15. Siciliano, S. J., Rollins, T. E., DeMartino, J., Konteatis, Z., Malkowitz, L., Van Riper, G., Bondy, S., Rosen, H. and Springer, M. S. 1994. Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors. Proc. Natl Acad. Sci. USA 91:1214.
16. DeMartino, J. A., Riper, G. V., Siciliano, S. J., Molineaux, C. J., Konteatis, Z. D., Rosen, H. and Springer, M. S. 1994. The amino terminus of the human C5a receptor is required for high affinity C5a binding and for receptor activation by C5a but not C5a analogs. J. Biol. Chem. 269:14446.
17. 2-terminal region of C5aR but not that of FPR is critical for both protein transport and ligand binding. J. Biol. Chem. 269:3457.
18. Gerard, C., Bao, L., Orozco, O., Person, M., Kunz, D. and Gerard, N. P. 1992. Structural diversity in the extracellular faces of peptidergic G-protein-coupled receptors: molecular cloning of the mouse C5a anaphylatoxin receptor. J. Immunol. 149:2600.
19. Perret, J. J., Paspe, E., Vassart, G. and Parmentier, M. 1992. Cloning and functional expression of the canine anaphylatoxin C5a receptor: evidence for high inferspecies variability. Biochem. J. 288:911.
20. Hugli, T. E. 1986. Biochemistry and biology of anaphylatoxin. Complement 3:111.
21. Fukuoka, Y., Tachibana, T. and Hugli, T. E. 1988. C5a receptors on guinea pig platelets. FASEB J. 2:A1008 (abstract).
22. Fukuoka, Y., Tachibana, T. and Kudo, T. 1994. Activation of guinea pig platelets by a monoclonal antibody. Thromb. Res. 73:431.
23. Hugli, T. E., Gerard, C., Kawahara, M., Scheetz, M. E., II, Barton, R., Briggs, S., Koppel., G. and Russell, S. 1981. Isolation of three separate anaphylatoxins from complement-activated human serum. Mol. Cell. Biochem. 41:59.
24. Prossnitz, E. R., Quehenberger, Q., Cochrane, C. G. and Ye, R. D. 1991. Transmembrane signaling by the N-formyl peptide receptor in stably transfected fibroblasts. Biochem. Biophys. Res. Commun. 179:471.
25. Kyte, J. and Doolittle, R. F. 1982. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:105.
26. Akatsu, H., Miwa, T., Sakurada, C., Fukuoka, Y., Ember, J. A., Yamamoto, T., Hugli, T. E. and Okada, H. 1997. cDNA cloning and characterization of rat C5a anaphylatoxin receptor. Microbiol. Immunol. 41:575.
27. Giannini, E., Brouchon, L. and Boulay, F. 1995. Identification of the major phosphorylation sites in human C5a anaphylatoxin receptor in vivo. J. Biol. Chem. 270:19166.
28. Fukuoka, Y. and Hugli, T. E. 1988. Demonstration of the specific C3a receptors on guinea pig platelets. J. Immunol. 140:3496.
29. Kretzschmar, T., Kahl, K., Rech, K., Bautsh, W., Kohl, J. and Bitter-Suermann, D. 1991. Characterization of the C5a receptor on guinea pig platelets. Immunobiology 183: 418.
30. Gerard, C. and Gerard, N. P. 1994. C5a anaphylatoxin and its seven transmembrane-segment receptor. Annu. Rev Immunol. 12:775.
31. Ames, R. S., Yi, I., Sarau, H. M., Nuthulaganti, P., Foley, J. J., Ellis, C., Zeng, Z., Su, K., Jurewicz, A. J., Hertzberg, R. P., Bergsma, D. J. and Kumar, C. 1996. Molecular cloning and characterization of human anaphylatoxin C3a receptor. J. Biol. Chem. 271:20231.
32. Crass, T., Raffetseder, U., Martin, U., Grove, M., Klos, A., Kohl, J. and Bautsch, W. 1996. Expression cloning of the human C3a anaphylatoxin receptor (C3aR) from differentiated U-937 cells. Eur. J. Immunol. 26:1944.
33. Roglic, A., Prossnitz, E. R., Cavanagh, S. L., Pan, Z., Zou, A. and Ye, R. D. 1996. cDNA cloning of a novel G protein-coupled receptor with a large extracellular loop structure. Biochim. Biophys. Acta 1305:39.
34. Tornetta, M. A., Foley, J. J., Sarau, H. M. and Ames, R. S. 1997. The mouse anaphylatoxin C3a receptor: molecular cloning, genomic organization and functional expression. J. Immunol. 158:5227.
35. Pease, J. E. and Baker, M. D. 1993. N-linked glycosylation of the C5a receptor. Biochem. Mol. Biol. Int. 31:719.
36. Monk, P. N., Baker, M. D., Partridge, L. J. and Pease, J. E. 1995. Mutation of glutamate 199 of the human C5a receptor defines a binding site for ligand distinct from the receptor N terminus. J. Biol. Chem. 270:16625.
37. DeMartino, J. A., Konteatis, Z. D., Siciliano, S. J., Riper, G. V., Underwood, D. J., Fisher, P. A. and Springer, M. S. 1995. Arginine 206 of the C5a receptor is critical for ligand recognition and receptor activation by C-terminal hexapeptide analogs. J. Biol. Chem. 270:15966.
38. Bock, D., Martin, U., Gartner, S., Rheinheimer, C., Raffetseder, U., Baker, M. D., Monk, P. N., Bautsch, W., Kohl, J. and Klos, A. 1997. The C terminus of the human C5a receptor (CD88) is required for normal ligand-dependent receptor internalization. Eur. J. Immunol. 27:1522.
39. Haviland, D. L., McCoy, R. L., Whitehead, W. T., Akama, H., Molmenti, E. P., Brown, A., Haviland, J. C., Parks, W. C., Perlmutter, D. H. and Wetsel, R. A. 1995. Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung. J. Immunol. 154:1861.
40. Buchner, R. R., Hugli, T. E., Ember, J. A. and Morgan, E. L. 1995. Expression of functional receptors for human C5a anaphylatoxin (CD88) on the human hepatocellular carcinoma cell line HepG2. J. Immunol. 155:308.
41. Schieferdecker, H. L., Rothermel, E., Timmermann, A., Götze, O. and Jungermann, K. 1997. Anaphylatoxin C5a receptor mRNA is strongly expressed in Kupffer and stellate cells and weakly in sinusoidal endothelial cells but not in hepatocytes of normal rat liver. FEBS Lett. 406:305.
42. Lacy, M., Jones, J., Whittemore, S. R., Haviland, D. L., Wetsel, R. A. and Barnum, S. R. 1995. Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia. J. Neuroimmunol. 61:71.
43. Gasque, P., Chan, P., Fontaine, M., Ischenko, A., Lamacz, M., Götze, O. and Morgan, B. P. 1995. Identification and characterization of the complement C5a anaphylatoxin receptor on human astrocytes. J. Immunol. 155:4882.
44. Gasque, P., Singhrao, S. K., Neal, J. W., Götze, O. and Morgan, B. P. 1997. Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia and endothelial cells in the inflamed human central nervous system. Am. J. Pathol. 150:31.
45. Muller-Ladner, U., Jones, J. L., Wetzel, R. A., Gay, S., Raine, C. S. and Barnum, S. R. 1996. Enhanced expression of chemotactic receptors in multiple sclerosis lesions. J. Neurolog. Sci. 144:135.
46. Stahel, P. F., Frei, K., Eugster, H-P., Fontana, A., Hummel, K. M., Wetzel, R. A., Ames, R. S. and Barnum S. R. 1997. TNF-α-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria Meningoencephalitis. J. Immunol. 159:861.