PPAR-gamma is expressed and NF-KB pathway is activated and correlates positively with COX-2 expression in stromal myofibroblasts surrounding colon adenocarcinomas

Journal of Cancer Research and Clinical Oncology

Volumn 132, Issue 2, 2006, Pages 76-84

  Vandoros, Gerasimos P ^a,b   Konstantinopoulos, Panagiotis A ^a,c   Sotiropoulou Bonikou, Georgia ^a   Kominea, Athina ^b   Papachristou, Georgios I ^a,d   Karamouzis, Michalis V ^a   Gkermpesi, Maria ^b   Varakis, Ioannis ^a   Papavassiliou, Athanasios G ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b Aeghion General Hospital   (Greece)

^c State University of New York Upstate Medical University: College of Medicine   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Colon cancer; Cyclooxygenase 2; Myofibroblasts; Nuclear factor kB; Peroxisome proliferator activated receptor gamma

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NONSTEROID ANTIINFLAMMATORY AGENT; PARAFFIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ADULT; AGED; ARTICLE; CANCER PREVENTION; CANCER STAGING; CHEMOPROPHYLAXIS; CLINICAL ARTICLE; COLON; COLON ADENOCARCINOMA; COLON CANCER; COLON MUCOSA; COLON TUMOR; COMPARATIVE STUDY; CORRELATION ANALYSIS; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MYOFIBROBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; STROMA CELL; TISSUE SECTION; UPREGULATION;

ADENOCARCINOMA; COLONIC NEOPLASMS; CYCLOOXYGENASE 2; ENDOTHELIAL CELLS; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MALE; MEMBRANE PROTEINS; MUSCLE CELLS; NF-KAPPA B; PPAR GAMMA; SIGNAL TRANSDUCTION; TUMOR MARKERS, BIOLOGICAL;

EID: 28644448573     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-005-0042-z     Document Type: Article

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