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Volumn 14, Issue 4, 2005, Pages 224-229

Real-time quantitative PCR analysis of regions involved in gene amplification reveals gene overdose in low-grade astrocytic gliomas

Author keywords

12q13 region; 1q32 region; Astrocytic gliomas; Gene amplification

Indexed keywords

MOLECULAR MARKER;

EID: 28444432659     PISSN: 10529551     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pas.0000177799.58336.1a     Document Type: Article
Times cited : (14)

References (39)
  • 2
    • 0344125975 scopus 로고    scopus 로고
    • Promoter hypermethylation of multiple genes in astrocytic gliomas
    • Gonzalez-Gomez P, Bello MJ, Arjona D, et al. Promoter hypermethylation of multiple genes in astrocytic gliomas. Int J Oncol. 2003;22:601-608.
    • (2003) Int J Oncol , vol.22 , pp. 601-608
    • Gonzalez-Gomez, P.1    Bello, M.J.2    Arjona, D.3
  • 3
    • 0027194766 scopus 로고
    • Gene and chromosomal alterations associated with the development of human gliomas
    • Collins VP, James CD. Gene and chromosomal alterations associated with the development of human gliomas. FASEB J. 1993;7:926-930.
    • (1993) FASEB J , vol.7 , pp. 926-930
    • Collins, V.P.1    James, C.D.2
  • 4
    • 10144259344 scopus 로고    scopus 로고
    • MDMX: A novel p53-binding protein with some functional properties of MDM2
    • Shvarts A, Steegenga WT, Riteco N, et al. MDMX: a novel p53-binding protein with some functional properties of MDM2. EMBO J. 1996;15: 5349-5357.
    • (1996) EMBO J , vol.15 , pp. 5349-5357
    • Shvarts, A.1    Steegenga, W.T.2    Riteco, N.3
  • 5
    • 0242580250 scopus 로고    scopus 로고
    • DNA damage-induced MDMX degradation is mediated by MDM2
    • Kawai H, Wiederschain D, Kitao H, et al. DNA damage-induced MDMX degradation is mediated by MDM2. J Biol Chem. 2003;278:45946-45953.
    • (2003) J Biol Chem , vol.278 , pp. 45946-45953
    • Kawai, H.1    Wiederschain, D.2    Kitao, H.3
  • 6
    • 0343819885 scopus 로고    scopus 로고
    • Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification
    • Riemenschneider MJ, Buschges R, Wolter M, et al. Amplification and overexpression of the MDM4 (MDMX) gene from 1q32 in a subset of malignant gliomas without TP53 mutation or MDM2 amplification. Cancer Res. 1999;59:6091-6096.
    • (1999) Cancer Res , vol.59 , pp. 6091-6096
    • Riemenschneider, M.J.1    Buschges, R.2    Wolter, M.3
  • 7
    • 0037431518 scopus 로고    scopus 로고
    • Refined mapping of 1q32 amplicons in malignant gliomas confirms MDM4 as the main amplification target
    • Riemenschneider MJ, Knobbe CB, Reifenberger G. Refined mapping of 1q32 amplicons in malignant gliomas confirms MDM4 as the main amplification target. Int J Cancer. 2003;104:752-757.
    • (2003) Int J Cancer , vol.104 , pp. 752-757
    • Riemenschneider, M.J.1    Knobbe, C.B.2    Reifenberger, G.3
  • 8
    • 0034039961 scopus 로고    scopus 로고
    • Amplification of the platelet-derived growth factor receptor-A (PDGFRA) gene occurs in oligodendrogliomas with grade IV anaplastic features
    • Smith JS, Wang XY, Qian J, et al. Amplification of the platelet-derived growth factor receptor-A (PDGFRA) gene occurs in oligodendrogliomas with grade IV anaplastic features. J Neuropathol Exp Neurol. 2000;59: 495-503.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 495-503
    • Smith, J.S.1    Wang, X.Y.2    Qian, J.3
  • 9
    • 9044248587 scopus 로고    scopus 로고
    • Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas
    • Hermanson M, Funa K, Koopmann J, et al. Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas. Cancer Res. 1996;56:164-171.
    • (1996) Cancer Res , vol.56 , pp. 164-171
    • Hermanson, M.1    Funa, K.2    Koopmann, J.3
  • 10
    • 0027978368 scopus 로고
    • Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: Preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2
    • Reifenberger G, Reifenberger J, Ichimura K, et al. Amplification of multiple genes from chromosomal region 12q13-14 in human malignant gliomas: Preliminary mapping of the amplicons shows preferential involvement of CDK4, SAS, and MDM2. Cancer Res. 1994;54:4299-4303.
    • (1994) Cancer Res , vol.54 , pp. 4299-4303
    • Reifenberger, G.1    Reifenberger, J.2    Ichimura, K.3
  • 11
    • 0029800810 scopus 로고    scopus 로고
    • Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets
    • Reifenberger G, Ichimura K, Reifenberger J, et al. Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets. Cancer Res. 1996;56: 5141-5145.
    • (1996) Cancer Res , vol.56 , pp. 5141-5145
    • Reifenberger, G.1    Ichimura, K.2    Reifenberger, J.3
  • 12
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y, Maya R, Kazaz A, et al. Mdm2 promotes the rapid degradation of p53. Nature. 1997;387:296-299.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3
  • 13
    • 0027673764 scopus 로고
    • The p53-mdm2 autoregulatory feedback loop: A paradigm for the regulation of growth control by p53?
    • Picksley SM, Lane DP. The p53-mdm2 autoregulatory feedback loop: A paradigm for the regulation of growth control by p53? Bioessays. 1993; 15:689-690.
    • (1993) Bioessays , vol.15 , pp. 689-690
    • Picksley, S.M.1    Lane, D.P.2
  • 14
    • 0028061974 scopus 로고
    • CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines
    • He J, Allen JR, Collins VP, et al. CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines. Cancer Res. 1994;54:5804-5807.
    • (1994) Cancer Res , vol.54 , pp. 5804-5807
    • He, J.1    Allen, J.R.2    Collins, V.P.3
  • 15
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr CJ. Cancer cell cycles. Science. 1996;274;1672-1677.
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 16
    • 0026627772 scopus 로고
    • Loss of heterozygosity for distal markers on 22q in human gliomas
    • Rey JA, Bello MJ, Jimenez-Lara AM, et al. Loss of heterozygosity for distal markers on 22q in human gliomas. Int J Cancer. 1992;51:703-706.
    • (1992) Int J Cancer , vol.51 , pp. 703-706
    • Rey, J.A.1    Bello, M.J.2    Jimenez-Lara, A.M.3
  • 17
    • 0035423813 scopus 로고    scopus 로고
    • Ribosomal 18S RNA prevails over glyceraldehyde-3-phosphate dehydrogenase and beta-actin genes as internal standard for quantitative comparison of mRNA levels in invasive and noninvasive human melanoma cell subpopulations
    • Goidin D, Mamessier A, Staquet MJ, et al. Ribosomal 18S RNA prevails over glyceraldehyde-3-phosphate dehydrogenase and beta-actin genes as internal standard for quantitative comparison of mRNA levels in invasive and noninvasive human melanoma cell subpopulations. Anal Biochem. 2001;295:17-21.
    • (2001) Anal Biochem , vol.295 , pp. 17-21
    • Goidin, D.1    Mamessier, A.2    Staquet, M.J.3
  • 18
    • 0036875688 scopus 로고    scopus 로고
    • Selection of an internal control gene for quantitation of mRNA in colonic tissues
    • Tsuji N, Kamagata C, Furuya M, et al. Selection of an internal control gene for quantitation of mRNA in colonic tissues. Anticancer Res. 2002; 22:4173-4178.
    • (2002) Anticancer Res , vol.22 , pp. 4173-4178
    • Tsuji, N.1    Kamagata, C.2    Furuya, M.3
  • 19
    • 21144436493 scopus 로고    scopus 로고
    • Real-Time Quantitative PCR analysis of gene dosages reveals gene amplification in low-grade oligodendrogliomas
    • Alonso ME, Bello MJ, Arjona D, et al. Real-Time Quantitative PCR analysis of gene dosages reveals gene amplification in low-grade oligodendrogliomas. Am J Clin Pathol. 2005;123:900-906.
    • (2005) Am J Clin Pathol , vol.123 , pp. 900-906
    • Alonso, M.E.1    Bello, M.J.2    Arjona, D.3
  • 20
    • 23044503235 scopus 로고    scopus 로고
    • Molecular analysis of the EGFR gene in astrocytic gliomas: MRNA expression, quantitative-PCR analysis of non homogeneous gene amplification and DNA sequence alterations
    • Arjona D, Bello MJ, Alonso ME, et al. Molecular analysis of the EGFR gene in astrocytic gliomas: mRNA expression, quantitative-PCR analysis of non homogeneous gene amplification and DNA sequence alterations. Neuropathol Appl Nleurobiol. 2005;31:384-394.
    • (2005) Neuropathol Appl Nleurobiol , vol.31 , pp. 384-394
    • Arjona, D.1    Bello, M.J.2    Alonso, M.E.3
  • 21
    • 7144259063 scopus 로고    scopus 로고
    • GAC1, a new member of the leucine-rich repeat superfamily on chromosome band 1q32.1, is amplified and overexpressed in malignant gliomas
    • Almeida A, Zhu XX, Vogt N, et al. GAC1, a new member of the leucine-rich repeat superfamily on chromosome band 1q32.1, is amplified and overexpressed in malignant gliomas. Oncogene. 1998;16:2997-3002.
    • (1998) Oncogene , vol.16 , pp. 2997-3002
    • Almeida, A.1    Zhu, X.X.2    Vogt, N.3
  • 22
    • 4344605095 scopus 로고    scopus 로고
    • Hypermethylation of the DNA repair gene MGMT: Association with TP53 G:C to A:T transitions in a series of 469 nervous system tumors
    • Bello MJ, Alonso ME, Aminoso C, et al. Hypermethylation of the DNA repair gene MGMT: association with TP53 G:C to A:T transitions in a series of 469 nervous system tumors. Mutat Res. 2004;554:23-32.
    • (2004) Mutat Res , vol.554 , pp. 23-32
    • Bello, M.J.1    Alonso, M.E.2    Aminoso, C.3
  • 23
    • 0036483708 scopus 로고    scopus 로고
    • Microvascular angiogenesis and the reninangiotensin system
    • Greene AS, Amaral SL. Microvascular angiogenesis and the reninangiotensin system. Curr Hypertens Rep. 2002;4:56-62.
    • (2002) Curr Hypertens Rep , vol.4 , pp. 56-62
    • Greene, A.S.1    Amaral, S.L.2
  • 25
    • 0023682851 scopus 로고
    • Renin in glioblastoma multiforme and its role in neovascularization
    • Ariza A, Fernandez LA, Inagami T, et al. Renin in glioblastoma multiforme and its role in neovascularization. Am J Clin Pathol. 1988;90: 437-441.
    • (1988) Am J Clin Pathol , vol.90 , pp. 437-441
    • Ariza, A.1    Fernandez, L.A.2    Inagami, T.3
  • 26
    • 1942520986 scopus 로고    scopus 로고
    • Renin and angiotensinogen expression and functions in growth and apoptosis of human glioblastoma
    • Juillerat-Jeanneret L, Celerier J, Chapuis BC, et al. Renin and angiotensinogen expression and functions in growth and apoptosis of human glioblastoma. Br J Cancer. 2004;90:1059-1068.
    • (2004) Br J Cancer , vol.90 , pp. 1059-1068
    • Juillerat-Jeanneret, L.1    Celerier, J.2    Chapuis, B.C.3
  • 27
    • 0033083686 scopus 로고    scopus 로고
    • Genomic organization of the human ELF3 (ESE-1/ESX) gene, a member of the Ets transcription factor family, and identification of a functional promoter
    • Oettgen P, Barcinski M, Boltax J, et al. Genomic organization of the human ELF3 (ESE-1/ESX) gene, a member of the Ets transcription factor family, and identification of a functional promoter. Genomics. 1999;55: 358-362.
    • (1999) Genomics , vol.55 , pp. 358-362
    • Oettgen, P.1    Barcinski, M.2    Boltax, J.3
  • 28
    • 0030656367 scopus 로고    scopus 로고
    • The expression of a novel, epithelium-specific ets transcription factor is restricted to the most differentiated layers in the epidermis
    • Andreoli JM, Jang SI, Chung E, et al. The expression of a novel, epithelium-specific ets transcription factor is restricted to the most differentiated layers in the epidermis. Nucleic Acids Res. 1997;25:4287-4295.
    • (1997) Nucleic Acids Res , vol.25 , pp. 4287-4295
    • Andreoli, J.M.1    Jang, S.I.2    Chung, E.3
  • 30
    • 8244259923 scopus 로고    scopus 로고
    • ESX: A structurally unique Ets overexpressed early during human breast tumorigenesis
    • Chang CH, Scott GK, Kuo WL, et al. ESX: a structurally unique Ets overexpressed early during human breast tumorigenesis. Oncogene. 1997; 14:1617-1622.
    • (1997) Oncogene , vol.14 , pp. 1617-1622
    • Chang, C.H.1    Scott, G.K.2    Kuo, W.L.3
  • 31
    • 0030667670 scopus 로고    scopus 로고
    • The novel epithelial-specific Ets transcription factor gene ESX maps to human chromosome 1q32.1
    • Oettgen P, Carter KC, Augustus M, et al. The novel epithelial-specific Ets transcription factor gene ESX maps to human chromosome 1q32.1. Genomics. 1997;45:456-457.
    • (1997) Genomics , vol.45 , pp. 456-457
    • Oettgen, P.1    Carter, K.C.2    Augustus, M.3
  • 32
    • 0029401049 scopus 로고
    • Platelet-derived growth factor in human glioma
    • Westermark B, Heldin CH, Nister M. Platelet-derived growth factor in human glioma. Glia. 1995;15:257-263.
    • (1995) Glia , vol.15 , pp. 257-263
    • Westermark, B.1    Heldin, C.H.2    Nister, M.3
  • 33
    • 0028911678 scopus 로고
    • Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop
    • Guha A, Dashner K, Black PM, et al. Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop. Int J Cancer. 1995;60:168-173.
    • (1995) Int J Cancer , vol.60 , pp. 168-173
    • Guha, A.1    Dashner, K.2    Black, P.M.3
  • 34
    • 0029398189 scopus 로고
    • Gene amplification in human gliomas
    • Collins VP. Gene amplification in human gliomas. Glia. 1995;15:289-296.
    • (1995) Glia , vol.15 , pp. 289-296
    • Collins, V.P.1
  • 35
  • 36
    • 0034649787 scopus 로고    scopus 로고
    • Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities
    • Ichimura K, Bolin MB, Goike HM, et al. Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities. Cancer Res. 2000;60:417-424.
    • (2000) Cancer Res , vol.60 , pp. 417-424
    • Ichimura, K.1    Bolin, M.B.2    Goike, H.M.3
  • 37
    • 0030778862 scopus 로고    scopus 로고
    • Amplification and overexpression of MDM2 in primary (de novo) glioblastomas
    • Biernat W, Kleihues P, Yonekawa Y, et al. Amplification and overexpression of MDM2 in primary (de novo) glioblastomas. J Neuropathol Exp Neurol. 1997;56:180-185.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 180-185
    • Biernat, W.1    Kleihues, P.2    Yonekawa, Y.3
  • 38
    • 0027980180 scopus 로고
    • Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes
    • Demetrick DJ, Zhang H, Beach DH. Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes. Cytogenet Cell Genet. 1994;66:72-74.
    • (1994) Cytogenet Cell Genet , vol.66 , pp. 72-74
    • Demetrick, D.J.1    Zhang, H.2    Beach, D.H.3
  • 39
    • 0029897610 scopus 로고    scopus 로고
    • Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme
    • Rollbrocker B, Waha A, Louis DN, et al. Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme. Acta Neuropathol (Berl). 1996;92:70-74.
    • (1996) Acta Neuropathol (Berl) , vol.92 , pp. 70-74
    • Rollbrocker, B.1    Waha, A.2    Louis, D.N.3


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