Genomic organization of the human ELF3 (ESE-1/ESX) gene, a member of the Ets transcription factor family, and identification of a functional promoter

Genomics

Volumn 55, Issue 3, 1999, Pages 358-362

  Oettgen, Peter ^a   Barcinski, Marcello ^b   Boltax, Jay ^a   Stolt, Peggy ^a   Akbarali, Yasmin ^a   Libermann, Towia A ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL CYCLE; CELL PROLIFERATION; DNA BINDING; EPITHELIUM CELL; EXON; GENOME; HUMAN; HUMAN CELL; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION;

ANIMALIA;

EID: 0033083686     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1998.5681     Document Type: Article

References (26)

1. Andreoli, J. M., Jang, S. I., Chung, E., Coticchia, C. M., Steinert, P. M., and Markova, N. G. (1997). The expression of a novel, epithelium-specific ets transcription factor is restricted to the most differentiated layers in the epidermis. Nucleic Acids Res. 25: 4287-4295.
2. Borles, J. C., Willerford, D. M., Grevin, D., Davidson, L., Camus, A., Martin, P., Stehelin, D., and Alt, F. W. (1995). Increased T-cell apoptosis and terminal B-cell differentiation induced by inactivation of the Ets-1 proto-oncogene. Nature 377: 635-638.
3. Breathnach, R., and Chambon, P. (1981). Organization and expression of eucaryotic split genes coding for proteins. Annu. Rev. Biochem. 50: 349-383.
4. Chang, C. H., Scott, G. K., Kuo, W. L., Xiong, X., Suzdaltseva, Y., Park, J. W., Sayre, P., Erny, K., Collins, C., Gray, J. W., and Benz, C. C. (1997). ESX: A structurally unique Ets overexpressed early during human breast tumorigenesis. Oncogene 14: 1617-1622.
5. Choi, S. G., Yi, Y., Kim, Y. S., Kato, M., Chang, J., Chung, H. W., Hahm, K. B., Yang, H. K., Rhee, H. H., Bang, Y. J., and Kim, S. J. (1998). A novel ets-related transcription factor, ERT/ESX/ ELF3, regulates expression of the transforming growth factor-beta type II receptor. J. Biol. Chem. 273: 110-117.
6. Delattre, O., Zucman, J., Plougastel, B., Desmaze, C., Melot, T., Peter, M., Kovar, H., Joubert, I., de Jong, P., Rouleau, G., et al. (1992). Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours. Nature 359: 162-165.
7. Golub, T. R., Barker, G. F., Bohlander, S. K., Hiebert, S. W., Ward, D. C., Bray, W. P., Morgan, E., Raimondi, S. C., Rowley, J. D., and Gilliland, D. G. (1995). Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. Proc. Natl. Acad. Sci. USA 9295: 4917-4921.
8. Golub, T. R., Barker, G. F., Lovett, M., and Gilliland, D. G. (1994). Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5:12) chromosomal translocation. Cell 77: 307-316.
9. Janknecht, R., and Nordheim, A. (1993). Gene regulation by Ets proteins. Biochim. Biophys. Acta. 1155: 346-356.
10. Libermann, T. A., Nusbaum, H. R., Razon, N., Kris, R., Lax, I., Soreq, H., Whittle, N., Waterfield, M. D., Ullrich, A., and Schlessinger, J. (1985). Amplification and overexpression of the EGF receptor gene in primary human glioblastomas. J. Cell. Sec. Suppl. 3: 161-172.
11. Mantovani, R. (1998). A survey of 178 NF-Y binding CCAAT boxes. Nucleic Acids Res. 26: 1135-1143.
12. Oettgen, P., Akbarali, Y., Boltax, J., Best, J., Kunsch, C., and Libermann, T. A. (1996). Characterization of NERF, a novel transcription factor related to the Ets factor ELF-1. Mol. Cell. Biol. 16: 5091-5106.
13. Oettgen, P., Alani, R. M., Barcinski, M. A., Brown, L., Akbarali, Y., Boltax, J., Kunsch, C., Munger, K., and Libermann, T. A. (1997). Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family. Mol. Cell. Biol. 17: 4419-4433.
14. Oettgen, P., Carter, K. C., Augustus, M., Barcinski, M., Boltax, J., Kunsch, C., and Libermann, T. A. (1997). The novel epithelial-specific Ets transcription factor gene ESX maps to human chromosome lq32.1. Genomics 45: 456-457.
15. Pahl, H. L., Rosmarin, A. G., and Tenen, D. G. (1992). Characterization of the myeloid-specific CD11b promoter. Blood 79: 865-870.
16. Pahl, H. L., Scheibe, R. J., Zhang, D. E., Chen, H. M., Galson, D. L., Maki, R. A., and Tenen, D. G. (1993). The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter. J. Biol. Chem. 268: 5014-5020.
17. Panagopoulos, I., Aman, P., Fioretos, T., Hoglund, M., Johansson, B., Mandahl, N., Heim, S., Behrendtz, M., and Mitelman, F. (1994). Fusion of the FUS gene with ERG in acute myeloid leukemia with t(16;21)(p11;q22). Genes Chromosomes Cancer 11: 256-262.
18. Papas, T. S., Watson, D. K., Sacchi, N., Fujiwara, S., Seth, A. K., Fisher, R. J., Bhat, N. K., Mavrothalassitis, G., Koizumi, S., Jorcyk, C. L., et al. (1990). ETS family of genes in leukemia and Down syndrome. Am. J. Med. Genet. Suppl. 7: 251-261.
19. Peter, M., Couturier, J., Pacquement, H., Michon, J., Thomas, G., Magdelenat, H., and Delattre, O. (1997). A new member of the ETS family fused to EWS in Ewing tumors. Oncogene 14: 1159-1164.
20. Peter, M., Mugneret, F., Aurias, A., Thomas, G., Magdelenat, H., and Delattre, O. (1996). An EWS/ERG fusion with a truncated N-terminal domain of EWS in a Ewing's tumor. Int. J. Cancer 67: 339-342.
21. Scott, E. W., Simon, M. C., Anastasi, J., and Singh, H. (1994). Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages. Science 265: 1573-1577.
22. Sumarsono, S. H., Wilson, T. J., Tymms, M. J., Venter, D. J., Corrick, C. M., Kola, R., Lahoud, M. H., Papas, T. S., Seth, A., and Kola, I. (1996). Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice. Nature 379: 534-537.
23. Tymms, M. J., Ng, A. Y., Thomas, R. S., Schutte, B. C., Zhou, J., Eyre, H. J., Sutherland, G. R., Seth, A., Rosenberg, M., Papas, T., Debouck, C., and Kola, I. (1997). A novel epithelial-expressed ETS gene, ELF3: Human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer. Oncogene 15: 2449-2462.
24. Wang, L. C., Kuo, F., Fujiwara, Y., Gilliland, D. G., Golub, T. R., and Orkin, S. H. (1997). Yolk sac angiogenic defect and intraembryonic apoptosis in mice lacking the Ets-related factor TEL. EMBO J. 16: 4374-4383.
25. Wasylyk, B., Hahn, S. L., and Giovane, A. (1993). The Ets family of transcription factors. Eur. J. Biochem. 211: 7-18.
26. Wong, J. M., and Bateman, E. (1994). TBP-DNA interactions in the minor groove discriminate between A:T and T:A base pairs. Nucleic Acids Res. 22: 1890-1896.