Inhibition of sphingolipid synthesis impairs cellular activation, cytokine production and proliferation in human lymphocytes

Biochemical Pharmacology

Volumn 71, Issue 1-2, 2005, Pages 126-135

  Blank, Norbert ^a   Schiller, Martin ^a   Gabler, Christoph ^b   Kalden, Joachim R ^b   Lorenz, Hanns Martin ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

IFN gamma; Membrane microdomains; T lymphocytes

Indexed keywords

2 DECANOYLAMINO 3 MORPHOLINO 1 PHENYL 1 PROPANOL; CERAMIDE; GAMMA INTERFERON; GLYCOSPHINGOLIPID; LAT PROTEIN; LIPID; MARKER; PROTEIN KINASE LCK; SPHINGOLIPID; SUPERANTIGEN; THERMOZYMOCIDIN;

ARTICLE; CELL ACTIVATION; CELL DEATH; CELL FUNCTION; CELL GROWTH; CELL MEMBRANE; CELL PROLIFERATION; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; T LYMPHOCYTE; WHOLE CELL;

CELL DIVISION; CELL PROLIFERATION; CHROMATOGRAPHY, THIN LAYER; CYTOKINES; HUMANS; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MEMBRANE MICRODOMAINS; MORPHOLINES; SPHINGOLIPIDS;

EID: 28244468089     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.10.004     Document Type: Article

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