메뉴 건너뛰기




Volumn 72, Issue 3, 1999, Pages 1040-1049

Differential effects of glycolipid biosynthesis inhibitors on ceramide- induced cell death in neuroblastoma cells

Author keywords

Apoptosis; Cell death; Gaucher's disease; Glycolipids; Neuroblastoma cells

Indexed keywords

2 DECANOYLAMINO 3 MORPHOLINO 1 PHENYL 1 PROPANOL; CERAMIDE; DAUNORUBICIN; ENZYME INHIBITOR; GLUCOSYLCERAMIDASE; GLUCOSYLCERAMIDE; MIGLUSTAT; SYNTHETASE;

EID: 0033005150     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0721040.x     Document Type: Article
Times cited : (61)

References (56)
  • 2
    • 0031905956 scopus 로고    scopus 로고
    • Role of sphingolipid-mediated cell death in neurodegenerative diseases
    • Ariga T., Jarvis W. D., and Yu R. K. (1998) Role of sphingolipid-mediated cell death in neurodegenerative diseases. J. Lipid Res. 39, 1-16.
    • (1998) J. Lipid Res. , vol.39 , pp. 1-16
    • Ariga, T.1    Jarvis, W.D.2    Yu, R.K.3
  • 3
    • 0026981191 scopus 로고
    • Inhibition of glucocerebrosidase and induction of neural abnormality by cyclophellitol in mice
    • Atsumi S., Nosaka C., Iinuma H., and Umezawa K. (1992) Inhibition of glucocerebrosidase and induction of neural abnormality by cyclophellitol in mice. Arch. Biochem. Biophys. 297, 362-367.
    • (1992) Arch. Biochem. Biophys. , vol.297 , pp. 362-367
    • Atsumi, S.1    Nosaka, C.2    Iinuma, H.3    Umezawa, K.4
  • 5
    • 0026024247 scopus 로고
    • Neunte outgrowth in dorsal root neuronal hybrid clones modulated by ganglioside GM1 and disintegrin
    • Barletta E., Bremer E. G., and Culp L. A. (1991) Neunte outgrowth in dorsal root neuronal hybrid clones modulated by ganglioside GM1 and disintegrin. Exp. Cell Res. 193, 101-111.
    • (1991) Exp. Cell Res. , vol.193 , pp. 101-111
    • Barletta, E.1    Bremer, E.G.2    Culp, L.A.3
  • 6
    • 0028972747 scopus 로고
    • 9-mannosidase from human kidney is expressed in COS cells as a Golgi resident type II transmembrane protein
    • 9-mannosidase from human kidney is expressed in COS cells as a Golgi resident type II transmembrane protein. Eur. J. Biochem. 233, 644-649.
    • (1995) Eur. J. Biochem. , vol.233 , pp. 644-649
    • Bieberich, E.1    Bause, E.2
  • 7
    • 0024328577 scopus 로고
    • Intracellular activity of lysosomal glucosylceramidase measured with 4-nonylumbelliferyl β-glucoside
    • Bieberich E. and Legler G. (1989) Intracellular activity of lysosomal glucosylceramidase measured with 4-nonylumbelliferyl β-glucoside. Biol. Chem. Hoppe Seyler 370, 809-817.
    • (1989) Biol. Chem. Hoppe Seyler , vol.370 , pp. 809-817
    • Bieberich, E.1    Legler, G.2
  • 8
    • 0031871233 scopus 로고    scopus 로고
    • Regulation of ganglioside metabolism by phosphorylation and dephosphorylation
    • Bieberich E., Freischütz B., Liour S.-S., and Yu R. K. (1998) Regulation of ganglioside metabolism by phosphorylation and dephosphorylation. J. Neurochem. 71, 972-979.
    • (1998) J. Neurochem. , vol.71 , pp. 972-979
    • Bieberich, E.1    Freischütz, B.2    Liour, S.-S.3    Yu, R.K.4
  • 9
    • 0030788099 scopus 로고    scopus 로고
    • Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines
    • Boix J., Llecha N., Yusle V.-J., and Comella J. X. (1997) Characterization of the cell death process induced by staurosporine in human neuroblastoma cell lines. Neuropharmacology 36, 811-821.
    • (1997) Neuropharmacology , vol.36 , pp. 811-821
    • Boix, J.1    Llecha, N.2    Yusle, V.-J.3    Comella, J.X.4
  • 10
    • 0029148660 scopus 로고
    • Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals
    • Bose R., Verheij M., Haimovitz-Friedman A., Scotto K., Fuks Z., and Kolesnick R. (1995) Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell 82, 405-415.
    • (1995) Cell , vol.82 , pp. 405-415
    • Bose, R.1    Verheij, M.2    Haimovitz-Friedman, A.3    Scotto, K.4    Fuks, Z.5    Kolesnick, R.6
  • 11
    • 0031938471 scopus 로고    scopus 로고
    • Inhibition of glycosphingolipid biosynthesis does not impair growth or morphogenesis of the postimplantation mouse embryo
    • Brigande J. V., Platt F. M., and Seyfried T. N. (1998) Inhibition of glycosphingolipid biosynthesis does not impair growth or morphogenesis of the postimplantation mouse embryo. J. Neurochem. 70, 871-882.
    • (1998) J. Neurochem. , vol.70 , pp. 871-882
    • Brigande, J.V.1    Platt, F.M.2    Seyfried, T.N.3
  • 12
    • 0026788002 scopus 로고
    • Key morphological features of apoptosis may occur in the absence of internucleosomal DNA degradation
    • Cohen G. M., Sun X.-M., Snowden R. T., Dinsdale D., and Skiletter D. N. (1992) Key morphological features of apoptosis may occur in the absence of internucleosomal DNA degradation. Biochem. J. 286, 331-334.
    • (1992) Biochem. J. , vol.286 , pp. 331-334
    • Cohen, G.M.1    Sun, X.-M.2    Snowden, R.T.3    Dinsdale, D.4    Skiletter, D.N.5
  • 13
    • 0020519332 scopus 로고
    • Ganglioside composition is regulated during differentiation in the neuroblastoma × glioma hybrid cell line NG108-15
    • Dahms N. M. and Schnaar R. L. (1983) Ganglioside composition is regulated during differentiation in the neuroblastoma × glioma hybrid cell line NG108-15. J. Neurosci. 3, 806-807.
    • (1983) J. Neurosci. , vol.3 , pp. 806-807
    • Dahms, N.M.1    Schnaar, R.L.2
  • 15
    • 0026317511 scopus 로고
    • Glycosidase inhibitors: Inhibition of N-linked oligosaccharide processing
    • Elbein A. D. (1991) Glycosidase inhibitors: inhibition of N-linked oligosaccharide processing. FASEB J. 5, 3055-3063.
    • (1991) FASEB J. , vol.5 , pp. 3055-3063
    • Elbein, A.D.1
  • 16
    • 0025365763 scopus 로고
    • A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis
    • Felding-Habermann B., Igarashi Y., Federson B., Park L. S., Radin N. S., Inokuchi J., Strassmann G., Handa K., and Hakomori S. (1990) A ceramide analogue inhibits T cell proliferative response through inhibition of glycosphingolipid synthesis and enhancement of N,N-dimethylsphingosine synthesis. Biochemistry 29, 6314-6322.
    • (1990) Biochemistry , vol.29 , pp. 6314-6322
    • Felding-Habermann, B.1    Igarashi, Y.2    Federson, B.3    Park, L.S.4    Radin, N.S.5    Inokuchi, J.6    Strassmann, G.7    Handa, K.8    Hakomori, S.9
  • 19
    • 0032508379 scopus 로고    scopus 로고
    • Purification and characterization of ceramide-activated protein phosphatase
    • Galadari S., Kishikawa K., Kamibayashi C., Mumby M. C., and Hannun Y. (1998) Purification and characterization of ceramide-activated protein phosphatase. Biochemistry 37, 11232-11238.
    • (1998) Biochemistry , vol.37 , pp. 11232-11238
    • Galadari, S.1    Kishikawa, K.2    Kamibayashi, C.3    Mumby, M.C.4    Hannun, Y.5
  • 20
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green D. R. and Reed J. C. (1998) Mitochondria and apoptosis. Science 281, 1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 21
    • 0024327045 scopus 로고
    • Structure determination of glucosyl β-N-(ω-O-linoleoyl)-acylsphingosine of human epidermis
    • Hamanaka S., Asagami C., Suzuki M., Inagaki F., and Suzuki A. (1989) Structure determination of glucosyl β-N-(ω-O-linoleoyl)-acylsphingosine of human epidermis. J. Biochem. (Tokyo) 105, 684-690.
    • (1989) J. Biochem. (Tokyo) , vol.105 , pp. 684-690
    • Hamanaka, S.1    Asagami, C.2    Suzuki, M.3    Inagaki, F.4    Suzuki, A.5
  • 22
    • 0030569507 scopus 로고    scopus 로고
    • Induction of apoptosis by sphingosine-1-phosphate in human hepatoma cells is associated with enhanced expression of bax gene product
    • Hung W. C. and Chuang L. Y. (1996) Induction of apoptosis by sphingosine-1-phosphate in human hepatoma cells is associated with enhanced expression of bax gene product. Biochem. Biophys. Res. Commun. 229, 11-15.
    • (1996) Biochem. Biophys. Res. Commun. , vol.229 , pp. 11-15
    • Hung, W.C.1    Chuang, L.Y.2
  • 23
    • 0030342593 scopus 로고    scopus 로고
    • Neuritogenesis, not receptor expression, of NG108-15 cells can be modulated by monosialoganglioside GM1
    • Hwang H.-M., Weng S.-C., Lo S.-K., Yu R. K., and Tsai W.-H. (1996) Neuritogenesis, not receptor expression, of NG108-15 cells can be modulated by monosialoganglioside GM1. Chin. J. Physiol. 39, 211-217.
    • (1996) Chin. J. Physiol. , vol.39 , pp. 211-217
    • Hwang, H.-M.1    Weng, S.-C.2    Lo, S.-K.3    Yu, R.K.4    Tsai, W.-H.5
  • 27
    • 0028817546 scopus 로고
    • Induction of apoptotic DNA fragmentation and cell death by natural ceramide
    • Ji L., Zhang G., Uematsu S., Akahori Y., and Hirabayashi Y. (1995) Induction of apoptotic DNA fragmentation and cell death by natural ceramide. FEBS Lett. 358, 211-214.
    • (1995) FEBS Lett. , vol.358 , pp. 211-214
    • Ji, L.1    Zhang, G.2    Uematsu, S.3    Akahori, Y.4    Hirabayashi, Y.5
  • 28
    • 0031012837 scopus 로고    scopus 로고
    • Inhibition of endogenous ganglioside synthesis does not block neurite formation by retinoic acid-treated neuroblastoma cells
    • Li R. and Ladisch S. (1997) Inhibition of endogenous ganglioside synthesis does not block neurite formation by retinoic acid-treated neuroblastoma cells. J. Biol. Chem. 272, 1349-1354.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1349-1354
    • Li, R.1    Ladisch, S.2
  • 29
    • 1842376234 scopus 로고    scopus 로고
    • Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin
    • Mansat V., Bettaieb A., Levade T., Laurent G., and Jaffrezou J.-P. (1997) Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin. FASEB J. 11, 695-702.
    • (1997) FASEB J. , vol.11 , pp. 695-702
    • Mansat, V.1    Bettaieb, A.2    Levade, T.3    Laurent, G.4    Jaffrezou, J.-P.5
  • 30
    • 0020320060 scopus 로고
    • Accumulation of glucosylceramide and glucosylsphingosine (psychosine) in cerebrum and cerebellum in infantile and juvenile Gaucher disease
    • Nilsson O. and Svennerholm L. (1982) Accumulation of glucosylceramide and glucosylsphingosine (psychosine) in cerebrum and cerebellum in infantile and juvenile Gaucher disease. J. Neurochem. 39, 709-718.
    • (1982) J. Neurochem. , vol.39 , pp. 709-718
    • Nilsson, O.1    Svennerholm, L.2
  • 31
    • 0029055676 scopus 로고
    • Ceramide: A stress signal and mediator of growth suppression and apoptosis
    • Obeid L. M. and Hannun Y. A. (1995) Ceramide: a stress signal and mediator of growth suppression and apoptosis. J. Cell. Biochem. 58, 191-198.
    • (1995) J. Cell. Biochem. , vol.58 , pp. 191-198
    • Obeid, L.M.1    Hannun, Y.A.2
  • 32
  • 33
    • 0028900748 scopus 로고
    • Induction of apoptosis by sphingosine in human leukemic HL-60 cells: A possible endogenous modulator of apoptotic DNA-fragmentation occurring during phorbolester induced differentiation
    • Ohta H., Sweeney E. A., Masamune A., Yatomi Y., Hakamori S., and Igarashi Y. (1995) Induction of apoptosis by sphingosine in human leukemic HL-60 cells: a possible endogenous modulator of apoptotic DNA-fragmentation occurring during phorbolester induced differentiation. Cancer Res. 55, 691-697.
    • (1995) Cancer Res. , vol.55 , pp. 691-697
    • Ohta, H.1    Sweeney, E.A.2    Masamune, A.3    Yatomi, Y.4    Hakamori, S.5    Igarashi, Y.6
  • 34
    • 0023733902 scopus 로고
    • Phenotypic changes in 3T3 cells associated with the change of sphingolipid synthesis by a ceramide analog, 2-decanoylamino-3-morpholino-i-phenylpropanol (compound RV 538)
    • Okada Y., Radin N. S., and Hakomori S. (1988) Phenotypic changes in 3T3 cells associated with the change of sphingolipid synthesis by a ceramide analog, 2-decanoylamino-3-morpholino-I-phenylpropanol (compound RV 538). FEBS Lett. 235, 25-29.
    • (1988) FEBS Lett. , vol.235 , pp. 25-29
    • Okada, Y.1    Radin, N.S.2    Hakomori, S.3
  • 35
    • 0028176432 scopus 로고
    • N-Butyldeoxinojirimycin is a novel inhibitor of glycolipid biosynthesis
    • Platt F. M., Neises G. R., Dwek R. A., and Butters T. D. (1994) N-Butyldeoxinojirimycin is a novel inhibitor of glycolipid biosynthesis. J. Biol. Chem. 269, 8362-8365.
    • (1994) J. Biol. Chem. , vol.269 , pp. 8362-8365
    • Platt, F.M.1    Neises, G.R.2    Dwek, R.A.3    Butters, T.D.4
  • 37
    • 0030020497 scopus 로고    scopus 로고
    • In vitro accumulation of glucocerebroside in neuroblastoma cells: A model for study of Gaucher disease pathobiology
    • Prence E. M., Chaturvedi P., and Newburg D. S. (1996) In vitro accumulation of glucocerebroside in neuroblastoma cells: a model for study of Gaucher disease pathobiology. J. Neurosci. Res. 43, 365-371.
    • (1996) J. Neurosci. Res. , vol.43 , pp. 365-371
    • Prence, E.M.1    Chaturvedi, P.2    Newburg, D.S.3
  • 38
    • 0029939988 scopus 로고    scopus 로고
    • Treatment of Gaucher disease with an enzyme inhibitor
    • Radin N. S. (1996) Treatment of Gaucher disease with an enzyme inhibitor. Glycoconj. J. 13, 153-157.
    • (1996) Glycoconj. J. , vol.13 , pp. 153-157
    • Radin, N.S.1
  • 40
    • 0028305232 scopus 로고
    • Effects of the glycosphingolipid synthesis inhibitor, PDMP, on lysosomes in cultured cells
    • Rosenwald A. G. and Pagano R. E. (1994) Effects of the glycosphingolipid synthesis inhibitor, PDMP, on lysosomes in cultured cells. J. Lipid Res. 35, 1232-1240.
    • (1994) J. Lipid Res. , vol.35 , pp. 1232-1240
    • Rosenwald, A.G.1    Pagano, R.E.2
  • 41
    • 0026755594 scopus 로고
    • Effects of a sphingolipid synthesis inhibitor on membrane transport through the secretory pathway
    • Rosenwald A. G., Machamer C. E., and Pagano R. E. (1992) Effects of a sphingolipid synthesis inhibitor on membrane transport through the secretory pathway. Biochemistry 31, 3581-3590.
    • (1992) Biochemistry , vol.31 , pp. 3581-3590
    • Rosenwald, A.G.1    Machamer, C.E.2    Pagano, R.E.3
  • 42
    • 0028933977 scopus 로고
    • A regulatory role for sphingolipids in neuronal growth. Inhibition of sphingolipid synthesis and degradation have opposite effects on axonal branching
    • Schwarz A., Rapaport E., Hirschberg K., and Futerman A. H. (1995) A regulatory role for sphingolipids in neuronal growth. Inhibition of sphingolipid synthesis and degradation have opposite effects on axonal branching. J. Biol. Chem. 270, 10990-10998.
    • (1995) J. Biol. Chem. , vol.270 , pp. 10990-10998
    • Schwarz, A.1    Rapaport, E.2    Hirschberg, K.3    Futerman, A.H.4
  • 44
    • 0025922179 scopus 로고
    • 3H]-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, an inhibitor of glucosylceramide synthesis, and the synergistic action of an inhibitor of microsomal monooxygenase
    • 3H]-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol, an inhibitor of glucosylceramide synthesis, and the synergistic action of an inhibitor of microsomal monooxygenase. J. Lipid Res. 32, 713-722.
    • (1991) J. Lipid Res. , vol.32 , pp. 713-722
    • Shukla, A.1    Radin, N.S.2
  • 45
    • 0029450049 scopus 로고
    • Disorders of sphingolipid activator proteins
    • Suzuki Y. (1995) Disorders of sphingolipid activator proteins. Nippon Rinsho 53, 3025-3027.
    • (1995) Nippon Rinsho , vol.53 , pp. 3025-3027
    • Suzuki, Y.1
  • 46
    • 49749155713 scopus 로고
    • Quantitative estimation of sialic acids. II. A colorimetric resorcinol hydrochloric acid method. Biochim
    • Svennerholm L. (1957) Quantitative estimation of sialic acids. II. A colorimetric resorcinol hydrochloric acid method. Biochim. Biophys. Acta 24, 604-611.
    • (1957) Biophys. Acta , vol.24 , pp. 604-611
    • Svennerholm, L.1
  • 47
    • 75949147538 scopus 로고
    • The gangliosides
    • Svennerholm L. (1964) The gangliosides. J. Lipid Res. 5, 145-154.
    • (1964) J. Lipid Res. , vol.5 , pp. 145-154
    • Svennerholm, L.1
  • 48
    • 0024993445 scopus 로고
    • Effect of an inhibitor of glucosylceramide synthesis on cultured rabbit skin fibroblasts
    • Uemura K., Sugiyama E., Tamai C., Hara A., Taketomi T., and Radin N. S. (1990) Effect of an inhibitor of glucosylceramide synthesis on cultured rabbit skin fibroblasts. J. Biochem. (Tokyo) 108, 525-530.
    • (1990) J. Biochem. (Tokyo) , vol.108 , pp. 525-530
    • Uemura, K.1    Sugiyama, E.2    Tamai, C.3    Hara, A.4    Taketomi, T.5    Radin, N.S.6
  • 49
    • 0025826378 scopus 로고
    • Effects of an inhibitor of glucosylceramide synthase on glycosphingolipid synthesis and neunte outgrowth in murine neuroblastoma cell lines
    • Uemura K., Sugiyama E., and Taketomi T. (1991) Effects of an inhibitor of glucosylceramide synthase on glycosphingolipid synthesis and neunte outgrowth in murine neuroblastoma cell lines. J. Biol. Chem. 110, 96-102.
    • (1991) J. Biol. Chem. , vol.110 , pp. 96-102
    • Uemura, K.1    Sugiyama, E.2    Taketomi, T.3
  • 50
    • 0024601171 scopus 로고
    • Coordinate regulation of ganglioside glycosyltransferases in differentiating NG108-15 neuroblastoma × glioma cells
    • Walton K. M. and Schnaar R. L. (1989) Coordinate regulation of ganglioside glycosyltransferases in differentiating NG108-15 neuroblastoma × glioma cells. J. Neurochem. 52, 1537-1544.
    • (1989) J. Neurochem. , vol.52 , pp. 1537-1544
    • Walton, K.M.1    Schnaar, R.L.2
  • 51
    • 0016637041 scopus 로고
    • Lowry determination of protein in the presence of Triton X-100
    • Wang C.-S. and Smith R. L. (1975) Lowry determination of protein in the presence of Triton X-100. Anal. Biochem. 63, 414-417.
    • (1975) Anal. Biochem. , vol.63 , pp. 414-417
    • Wang, C.-S.1    Smith, R.L.2
  • 52
    • 0030445804 scopus 로고    scopus 로고
    • Induction of apoptotic cell death in hen granulosa cells by ceramide
    • Witty J. P., Bridgham J. T., and Johnson A. L. (1996) Induction of apoptotic cell death in hen granulosa cells by ceramide. Endocrinology 137, 5269-5277.
    • (1996) Endocrinology , vol.137 , pp. 5269-5277
    • Witty, J.P.1    Bridgham, J.T.2    Johnson, A.L.3
  • 53
    • 0029070835 scopus 로고
    • Purification and biochemical characterization of membrane-bound epidermal ceramides form guinea pig skin
    • Yada Y., Higuchi K., and Imokawa G. (1995) Purification and biochemical characterization of membrane-bound epidermal ceramides form guinea pig skin. J. Biol. Chem. 270, 12677-12684.
    • (1995) J. Biol. Chem. , vol.270 , pp. 12677-12684
    • Yada, Y.1    Higuchi, K.2    Imokawa, G.3
  • 54
    • 0029081151 scopus 로고
    • Clear differences in ceramide metabolism between glycosphingolipids and sphingomyelin in a human promyelotic leukemia cell line HL-60 stimulated by a differentiation inducer
    • Yokoyama K., Nojiri H., Suzuki M., Setaka M., Suzuki A., and Nojima S. (1995) Clear differences in ceramide metabolism between glycosphingolipids and sphingomyelin in a human promyelotic leukemia cell line HL-60 stimulated by a differentiation inducer. FEBS Lett. 368, 477-480.
    • (1995) FEBS Lett. , vol.368 , pp. 477-480
    • Yokoyama, K.1    Nojiri, H.2    Suzuki, M.3    Setaka, M.4    Suzuki, A.5    Nojima, S.6
  • 56
    • 0028212835 scopus 로고
    • Developmental regulation of ganglioside metabolism
    • Yu R. K. (1994) Developmental regulation of ganglioside metabolism. Prog. Brain Res. 101, 31-44.
    • (1994) Prog. Brain Res. , vol.101 , pp. 31-44
    • Yu, R.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.