-
1
-
-
0026470429
-
Contributions of heme and nonheme iron to human nutrition
-
Carpenter CE, Mahoney AW: Contributions of heme and nonheme iron to human nutrition. Crit Rev Food Sci Nutr 1992, 31:333-367.
-
(1992)
Crit. Rev. Food Sci. Nutr.
, vol.31
, pp. 333-367
-
-
Carpenter, C.E.1
Mahoney, A.W.2
-
2
-
-
4544259474
-
Proton pump inhibitors and iron deficiency: Is the connection real?
-
Nand S, Tanvetyanon T: Proton pump inhibitors and iron deficiency: Is the connection real? South Med J 2004, 97:799.
-
(2004)
South Med. J.
, vol.97
, pp. 799
-
-
Nand, S.1
Tanvetyanon, T.2
-
3
-
-
13944278864
-
Iron-deficiency anemia and Helicobacter pylori infection: A review of the evidence
-
DuBois S, Kearney DJ: Iron-deficiency anemia and Helicobacter pylori infection: a review of the evidence. Am J Gastroenterol 2005, 100:453-459.
-
(2005)
Am. J. Gastroenterol.
, vol.100
, pp. 453-459
-
-
DuBois, S.1
Kearney, D.J.2
-
4
-
-
20144388176
-
The prevalence of celiac disease in average-risk and at-risk Western European populations: A systematic review
-
Dubé C, Rostom A, Sy R, et al.: The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review. Gastroenterology 2005, 128:S57-S67.
-
(2005)
Gastroenterology
, vol.128
-
-
Dubé, C.1
Rostom, A.2
Sy, R.3
-
5
-
-
0035793856
-
An iron-regulated ferric reductase associated with the absorption of dietary iron
-
McKie AT, Barrow D, Latunde-Dada GO, et al.: An iron-regulated ferric reductase associated with the absorption of dietary iron. Science 2001, 291:1755-1759.
-
(2001)
Science
, vol.291
, pp. 1755-1759
-
-
McKie, A.T.1
Barrow, D.2
Latunde-Dada, G.O.3
-
6
-
-
0030763856
-
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
-
Fleming MD, Trenor III CC, Su MA, et al.: Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat Genet 1997, 16:383-386.
-
(1997)
Nat. Genet.
, vol.16
, pp. 383-386
-
-
Fleming, M.D.1
Trenor III, C.C.2
Su, M.A.3
-
7
-
-
0030755366
-
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
-
Gunshin H, Mackenzie B, Berger UV, et al.: Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 1997, 388:482-488.
-
(1997)
Nature
, vol.388
, pp. 482-488
-
-
Gunshin, H.1
Mackenzie, B.2
Berger, U.V.3
-
8
-
-
0033861745
-
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
-
McKie AT, Marciani P, Rolfs A, et al.: A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell 2000, 5:299-309.
-
(2000)
Mol. Cell
, vol.5
, pp. 299-309
-
-
McKie, A.T.1
Marciani, P.2
Rolfs, A.3
-
9
-
-
0034677467
-
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
-
Donovan A, Brownlie A, Zhou Y, et al.: Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 2000, 403:776-781.
-
(2000)
Nature
, vol.403
, pp. 776-781
-
-
Donovan, A.1
Brownlie, A.2
Zhou, Y.3
-
10
-
-
0034733635
-
A novel mammalian iron-regulated protein involved in intracellular iron metabolism
-
Abboud S, Haile DJ: A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem 2000, 275:19906-19912.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 19906-19912
-
-
Abboud, S.1
Haile, D.J.2
-
11
-
-
0032909207
-
Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse
-
Vulpe CD, Kuo Y, Murphy TL, et al.: Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse. Nat Genet 1999, 21:195-199.
-
(1999)
Nat. Genet.
, vol.21
, pp. 195-199
-
-
Vulpe, C.D.1
Kuo, Y.2
Murphy, T.L.3
-
12
-
-
0035902605
-
Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
-
Nicolas G, Bennoun M, Devaux I, et al.: Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci U S A 2001, 98:8780-8785.
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
-
13
-
-
0037460697
-
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homeostasis
-
Bridle KR, Frazer DM, Wilkins SJ, et al.: Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homeostasis. Lancet 2003, 361:669-673.
-
(2003)
Lancet
, vol.361
, pp. 669-673
-
-
Bridle, K.R.1
Frazer, D.M.2
Wilkins, S.J.3
-
14
-
-
13544250486
-
Hepcidin is decreased in TFR2 hemochromatosis
-
Nemeth E, Roetto A, Garozzo G, et al.: Hepcidin is decreased in TFR2 hemochromatosis. Blood 2005, 105:1803-1806.
-
(2005)
Blood
, vol.105
, pp. 1803-1806
-
-
Nemeth, E.1
Roetto, A.2
Garozzo, G.3
-
15
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou G, Samuels ME, Ludwig EH, et al.: Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet 2004, 36:77-82.
-
(2004)
Nat. Genet.
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
-
16
-
-
24144459870
-
Identification of an intestinal heme transporter
-
in press
-
Shayeghi M, Latunde-dada GO, Oakhill JS, et al.: Identification of an intestinal heme transporter. Cell 2005, in press.
-
(2005)
Cell
-
-
Shayeghi, M.1
Latunde-Dada, G.O.2
Oakhill, J.S.3
-
17
-
-
0016326163
-
Intestinal absorption of hemoglobin iron: Heme cleavage by mucosal heme oxygenase
-
Raffin SB, Woo CH, Roost KT, et al.: Intestinal absorption of hemoglobin iron: heme cleavage by mucosal heme oxygenase. J Clin Invest 1974, 54:1344-1352.
-
(1974)
J. Clin. Invest.
, vol.54
, pp. 1344-1352
-
-
Raffin, S.B.1
Woo, C.H.2
Roost, K.T.3
-
18
-
-
3142781945
-
Iron, ferritin, and nutrition
-
Theil EC: Iron, ferritin, and nutrition. Annu Rev Nutr 2004, 24:327-343.
-
(2004)
Annu. Rev. Nutr.
, vol.24
, pp. 327-343
-
-
Theil, E.C.1
-
19
-
-
0032477866
-
NRAMP2 is mutated in the anemic Belgrade (b) rat: Evidence of a role for Nramp2 in endosomal iron transport
-
Fleming MD, Romano MA, Su MA, et al.: NRAMP2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci U S A 1998, 95:1148-1153.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 1148-1153
-
-
Fleming, M.D.1
Romano, M.A.2
Su, M.A.3
-
20
-
-
1342281234
-
SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1
-
Mackenzie B, Hediger MA: SLC11 family of H+-coupled metal-ion transporters NRAMP1 and DMT1. Pflugers Arch 2004, 447:571-579.
-
(2004)
Pflugers Arch.
, vol.447
, pp. 571-579
-
-
Mackenzie, B.1
Hediger, M.A.2
-
21
-
-
4644301624
-
Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis
-
Frazer DM, Inglis HR, Wilkins SJ, et al.: Delayed hepcidin response explains the lag period in iron absorption following a stimulus to increase erythropoiesis. Gut 2004, 53:1509-1515.
-
(2004)
Gut
, vol.53
, pp. 1509-1515
-
-
Frazer, D.M.1
Inglis, H.R.2
Wilkins, S.J.3
-
22
-
-
0032104739
-
The human Nramp2 gene: Characterization of the gene structure, alternative splicing, promotor region and polymorphisms
-
Lee PL, Gelbart T, West C, et al.: The human Nramp2 gene: characterization of the gene structure, alternative splicing, promotor region and polymorphisms. Blood Cells Mol Dis 1998, 24:199-215.
-
(1998)
Blood Cells Mol. Dis.
, vol.24
, pp. 199-215
-
-
Lee, P.L.1
Gelbart, T.2
West, C.3
-
23
-
-
0034070941
-
Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload
-
Trinder D, Oates PS, Thomas C, et al.: Localisation of divalent metal transporter 1 (DMT1) to the microvillus membrane of rat duodenal enterocytes in iron deficiency, but to hepatocytes in iron overload. Gut 2000, 46:270-276.
-
(2000)
Gut
, vol.46
, pp. 270-276
-
-
Trinder, D.1
Oates, P.S.2
Thomas, C.3
-
24
-
-
12844260664
-
Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload
-
Mims MP, Guan Y, Pospisilova D, et al.: Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload. Blood 2005, 105:1337-1342.
-
(2005)
Blood
, vol.105
, pp. 1337-1342
-
-
Mims, M.P.1
Guan, Y.2
Pospisilova, D.3
-
25
-
-
0025824547
-
Regulation of intestinal iron absorption and mucosal iron kinetics in hereditary hemochromatosis
-
McLaren GD, Nathanson MH, Jacobs A, et al.: Regulation of intestinal iron absorption and mucosal iron kinetics in hereditary hemochromatosis. J Lab Clin Med 1991, 117:390-401.
-
(1991)
J. Lab. Clin. Med.
, vol.117
, pp. 390-401
-
-
McLaren, G.D.1
Nathanson, M.H.2
Jacobs, A.3
-
26
-
-
20444416123
-
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
-
Donovan A, Lima CA, Pinkus JL, et al.: The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metabolism 2005, 1:191-200.
-
(2005)
Cell Metabolism
, vol.1
, pp. 191-200
-
-
Donovan, A.1
Lima, C.A.2
Pinkus, J.L.3
-
27
-
-
0034786537
-
Cloning and gastrointestinal expression of hephaestin: Relationship to other iron transport proteins
-
Frazer DM, Vulpe CD, McKie AT, et al.: Cloning and gastrointestinal expression of hephaestin: relationship to other iron transport proteins. Am J Physiol 2001, 281:G931-G939.
-
(2001)
Am. J. Physiol.
, vol.281
-
-
Frazer, D.M.1
Vulpe, C.D.2
McKie, A.T.3
-
28
-
-
2342508341
-
Hephaestin is a ferroxidase that maintains partial activity in sex-linked anemia mice
-
Chen H, Attieh ZK, Su T, et al.: Hephaestin is a ferroxidase that maintains partial activity in sex-linked anemia mice. Blood 2004, 103:3933-3939.
-
(2004)
Blood
, vol.103
, pp. 3933-3939
-
-
Chen, H.1
Attieh, Z.K.2
Su, T.3
-
29
-
-
1642451921
-
Mislocalisation of hephaestin, a multicopper ferroxidase involved in basolateral intestinal iron transport, in the sex linked anaemia mouse
-
Kuo YM, Su T, Chen H, et al.: Mislocalisation of hephaestin, a multicopper ferroxidase involved in basolateral intestinal iron transport, in the sex linked anaemia mouse. Gut 2004, 53:201-206.
-
(2004)
Gut
, vol.53
, pp. 201-206
-
-
Kuo, Y.M.1
Su, T.2
Chen, H.3
-
31
-
-
23044508432
-
Resistance to hepcidin is conferred by hemochromatosis-associated mutations of ferroportin
-
Drakesmith H, Schimanski LM, Ormerod E, et al.: Resistance to hepcidin is conferred by hemochromatosis-associated mutations of ferroportin. Blood 2005, 106:1092-1097.
-
(2005)
Blood
, vol.106
, pp. 1092-1097
-
-
Drakesmith, H.1
Schimanski, L.M.2
Ormerod, E.3
-
32
-
-
0028049495
-
Regulators of iron balance in humans
-
Finch C: Regulators of iron balance in humans. Blood 1994, 84:1697-1702.
-
(1994)
Blood
, vol.84
, pp. 1697-1702
-
-
Finch, C.1
-
33
-
-
0013361913
-
Regulation of intestinal iron transport
-
Edited by Templeton DM. New York: Marcel Dekker, Inc
-
Anderson GJ, Vulpe CD: Regulation of intestinal iron transport. In Molecular and Cellular Iron Transport. Edited by Templeton DM. New York: Marcel Dekker, Inc; 2002:559-598.
-
(2002)
Molecular and Cellular Iron Transport
, pp. 559-598
-
-
Anderson, G.J.1
Vulpe, C.D.2
-
34
-
-
0030841393
-
Iron, infections, and anemia of inflammation
-
Jurado RL: Iron, infections, and anemia of inflammation. Clin Infect Dis 1997, 25:888-895.
-
(1997)
Clin. Infect. Dis.
, vol.25
, pp. 888-895
-
-
Jurado, R.L.1
-
35
-
-
9344224529
-
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
-
Feder JN, Gnirke A, Thomas W, et al.: A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 1996, 13:399-408.
-
(1996)
Nat. Genet.
, vol.13
, pp. 399-408
-
-
Feder, J.N.1
Gnirke, A.2
Thomas, W.3
-
37
-
-
0034022636
-
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
-
Camaschella C, Roetto A, Calì A, et al.: The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22. Nat Genet 2000, 25:14-15.
-
(2000)
Nat. Genet.
, vol.25
, pp. 14-15
-
-
Camaschella, C.1
Roetto, A.2
Calì, A.3
-
38
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto A, Papanikolaou G, Politou M, et al.: Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet 2003, 33:21-22.
-
(2003)
Nat. Genet.
, vol.33
, pp. 21-22
-
-
Roetto, A.1
Papanikolaou, G.2
Politou, M.3
-
39
-
-
0033597780
-
Molecular cloning of transferrin receptor 2: A new member of the transferrin receptor-like family
-
Kawabata H, Yang R, Hirama T, et al.: Molecular cloning of transferrin receptor 2: a new member of the transferrin receptor-like family. J Biol Chem 1999, 274:20826-20832.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 20826-20832
-
-
Kawabata, H.1
Yang, R.2
Hirama, T.3
-
40
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ, Ganz T: Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 2001, 276:7806-7810.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
Ganz, T.4
-
41
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C, Ilyin G, Courselaud B, et al.: A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 2001, 276:7811-7819.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
-
42
-
-
0037007064
-
Severe iron deficiency anemia in transgenic mice expressing liver hepcidin
-
Nicolas G, Bennon M, Porteu A, et al.: Severe iron deficiency anemia in transgenic mice expressing liver hepcidin. Proc Natl Acad Sci U S A 2002, 99:4596-4601.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 4596-4601
-
-
Nicolas, G.1
Bennon, M.2
Porteu, A.3
-
43
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L, et al.: The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 2002, 110:1037-1044.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
-
44
-
-
2342425296
-
Changes in the expression of intestinal iron transport and hepatic regulatory molecules explain the enhanced iron absorption associated with pregnancy in the rat
-
Millard KN, Frazer DM, Wilkins SJ, Anderson GJ: Changes in the expression of intestinal iron transport and hepatic regulatory molecules explain the enhanced iron absorption associated with pregnancy in the rat. Gut 2004, 53:655-660.
-
(2004)
Gut
, vol.53
, pp. 655-660
-
-
Millard, K.N.1
Frazer, D.M.2
Wilkins, S.J.3
Anderson, G.J.4
-
45
-
-
0036727925
-
Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats
-
Frazer DM, Wilkins SJ, Becker EM, et al.: Hepcidin expression inversely correlates with the expression of duodenal iron transporters and iron absorption in rats. Gastroenterology 2002, 123:835-844.
-
(2002)
Gastroenterology
, vol.123
, pp. 835-844
-
-
Frazer, D.M.1
Wilkins, S.J.2
Becker, E.M.3
-
46
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, et al.: Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 2004, 306:2090-2093.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
-
47
-
-
0030712463
-
Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis
-
Parkkila S, Waheed A, Britton RS, et al.: Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis. Proc Natl Acad Sci U S A 1997, 94:13198-13202.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 13198-13202
-
-
Parkkila, S.1
Waheed, A.2
Britton, R.S.3
-
48
-
-
0038312385
-
Decreased liver hepcidin expression in the Hfe knockout mouse
-
Ahmad KA, Ahmann JR, Migas MC, et al.: Decreased liver hepcidin expression in the Hfe knockout mouse. Blood Cells Mol Dis 2002, 29:361-366.
-
(2002)
Blood Cells Mol. Dis.
, vol.29
, pp. 361-366
-
-
Ahmad, K.A.1
Ahmann, J.R.2
Migas, M.C.3
-
49
-
-
0037847496
-
Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis
-
Nicolas G, Viatte L, Lou DQ, et al.: Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis. Nat Genet 2003, 34:97-101.
-
(2003)
Nat. Genet.
, vol.34
, pp. 97-101
-
-
Nicolas, G.1
Viatte, L.2
Lou, D.Q.3
-
50
-
-
0037962795
-
The orchestration of body iron intake: How and where do enterocytes receive their cues?
-
Frazer DM, Anderson GJ: The orchestration of body iron intake: How and where do enterocytes receive their cues? Blood Cells Mol Dis 2003, 30:288-297.
-
(2003)
Blood Cells Mol. Dis.
, vol.30
, pp. 288-297
-
-
Frazer, D.M.1
Anderson, G.J.2
|