-
1
-
-
0028243847
-
-
(a) Gallop, M. A.; Barrett, R. W.; Dower, W.; Fodor, S. P. A.; Gordon, E. M. J. Med. Chem. 1994, 37, 1233-1385.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 1233-1385
-
-
Gallop, M.A.1
Barrett, R.W.2
Dower, W.3
Fodor, S.P.A.4
Gordon, E.M.5
-
3
-
-
0000512227
-
-
(c) Armstrong, R. W.; Combs, A. P.; Tempest, P. A.; Brown, S. D.; Keating, T. A. Acc. Chem. Res. 1996, 29, 123-131.
-
(1996)
Acc. Chem. Res.
, vol.29
, pp. 123-131
-
-
Armstrong, R.W.1
Combs, A.P.2
Tempest, P.A.3
Brown, S.D.4
Keating, T.A.5
-
5
-
-
0029930278
-
-
Hemkens, P. H.; Ottenheim, H. C.; Rees, D. Tetrahedron 1996, 52, 4527-4554.
-
(1996)
Tetrahedron
, vol.52
, pp. 4527-4554
-
-
Hemkens, P.H.1
Ottenheim, H.C.2
Rees, D.3
-
7
-
-
17244383040
-
-
(f) Ziegert, R. E.; Toräng, J.; Knepper, K.; Bräse, S. J. Comb. Chem. 2005, 7, 147-169.
-
(2005)
J. Comb. Chem.
, vol.7
, pp. 147-169
-
-
Ziegert, R.E.1
Toräng, J.2
Knepper, K.3
Bräse, S.4
-
8
-
-
0032485313
-
-
(a) Cotterill, I. C.; Usyatinsky, A. Y.; Arnold, J. M.; Clark, D. S.; Dordick, J. S.; Michels, P. C.; Khmelnitsky, Y. L. Tetrahedron Lett. 1998, 39, 1117-1120.
-
(1998)
Tetrahedron Lett.
, vol.39
, pp. 1117-1120
-
-
Cotterill, I.C.1
Usyatinsky, A.Y.2
Arnold, J.M.3
Clark, D.S.4
Dordick, J.S.5
Michels, P.C.6
Khmelnitsky, Y.L.7
-
9
-
-
0013021290
-
-
(b) Bagley, M. C.; Dale, J. W.; Ohnesorge, M.; Xiong, X.; Bower, J. J. Comb. Chem. 2003, 5, 41-44.
-
(2003)
J. Comb. Chem.
, vol.5
, pp. 41-44
-
-
Bagley, M.C.1
Dale, J.W.2
Ohnesorge, M.3
Xiong, X.4
Bower, J.5
-
10
-
-
0141795462
-
-
(c) Fujimori, T.; Wirsching, P.; Janda, K. D. J. Comb. Chem. 2003, 5, 625-631.
-
(2003)
J. Comb. Chem.
, vol.5
, pp. 625-631
-
-
Fujimori, T.1
Wirsching, P.2
Janda, K.D.3
-
11
-
-
0041336779
-
-
(d) Abbiati, G.; Arcadi, A.; Bianchi, G.; Di Giuseppe, S.; Marinelli, F.; Rossi, E. J. Org. Chem. 2003, 68, 6959-6966.
-
(2003)
J. Org. Chem.
, vol.68
, pp. 6959-6966
-
-
Abbiati, G.1
Arcadi, A.2
Bianchi, G.3
Di Giuseppe, S.4
Marinelli, F.5
Rossi, E.6
-
12
-
-
0037450398
-
-
(e) Bashford, K. E.; Burton, M. B.; Cameron, S.; Cooper, A. L.; Hogg, R. D.; Kane, P. D.; MacManus, D. A.; Matrunola, C. A.; Moody, C. J.; Robertson, A. A. B.; Warne, M. R. Tetrahedron Lett. 2003, 44, 1627-1629.
-
(2003)
Tetrahedron Lett.
, vol.44
, pp. 1627-1629
-
-
Bashford, K.E.1
Burton, M.B.2
Cameron, S.3
Cooper, A.L.4
Hogg, R.D.5
Kane, P.D.6
MacManus, D.A.7
Matrunola, C.A.8
Moody, C.J.9
Robertson, A.A.B.10
Warne, M.R.11
-
13
-
-
20044391821
-
-
(f) Martinez-Teipel, B.; Teixido, J.; Pascual, R.; Mora, M.; Pujola, J.; Fujimoto, T.; Borrell, J. I.; Michelotti, E. L. J. Comb Chem. 2005, 7, 436-448.
-
(2005)
J. Comb Chem.
, vol.7
, pp. 436-448
-
-
Martinez-Teipel, B.1
Teixido, J.2
Pascual, R.3
Mora, M.4
Pujola, J.5
Fujimoto, T.6
Borrell, J.I.7
Michelotti, E.L.8
-
14
-
-
0000257350
-
-
(a) Tadesse, S.; Bhandari, A.; Gallop, M. A. J. Comb. Chem. 1999, 1, 184-187.
-
(1999)
J. Comb. Chem.
, vol.1
, pp. 184-187
-
-
Tadesse, S.1
Bhandari, A.2
Gallop, M.A.3
-
15
-
-
0345580223
-
-
(b) Grosche, P.; Holtzel, A.; Walk, T. B.; Trautwein, A. W.; Jung, G. Synthesis 1999, 11, 1961-1970.
-
(1999)
Synthesis
, vol.11
, pp. 1961-1970
-
-
Grosche, P.1
Holtzel, A.2
Walk, T.B.3
Trautwein, A.W.4
Jung, G.5
-
16
-
-
0040077869
-
-
(c) Katritzky, A. R.; Chassaing, C.; Barrow, S. J.; Zhang, Z.; Vvedensky, V.; Forood, B. J. Comb. Chem. 2002, 4, 249-250.
-
(2002)
J. Comb. Chem.
, vol.4
, pp. 249-250
-
-
Katritzky, A.R.1
Chassaing, C.2
Barrow, S.J.3
Zhang, Z.4
Vvedensky, V.5
Forood, B.6
-
17
-
-
0037118360
-
-
(d) Gros, P.; Louërat, F.; Fort, Y. Org. Lett. 2002, 4, 1759-1761.
-
(2002)
Org. Lett.
, vol.4
, pp. 1759-1761
-
-
Gros, P.1
Louërat, F.2
Fort, Y.3
-
18
-
-
0037829773
-
-
(e) Louërat, F.; Gros, P.; Fort, Y. Tetrahedron Lett. 2003, 44, 5613-5616.
-
(2003)
Tetrahedron Lett.
, vol.44
, pp. 5613-5616
-
-
Louërat, F.1
Gros, P.2
Fort, Y.3
-
21
-
-
2342580816
-
-
(c) Zhang, L.; Pavlova, O. A.; Chefer, S. I.; Hall, A. W.; Kurian, V.; Brown, L. L.; Kimes, A. S.; Mukhin, A. G.; Horti, A. G. J. Med. Chem. 2004, 47, 2453-2465.
-
(2004)
J. Med. Chem.
, vol.47
, pp. 2453-2465
-
-
Zhang, L.1
Pavlova, O.A.2
Chefer, S.I.3
Hall, A.W.4
Kurian, V.5
Brown, L.L.6
Kimes, A.S.7
Mukhin, A.G.8
Horti, A.G.9
-
22
-
-
0000862058
-
-
(a) Burrow, M. P.; Gray, G. W.; Lacey, D.; Toyne, K. J. Liq. Cryst. 1988, 3, 1643-1653.
-
(1988)
Liq. Cryst.
, vol.3
, pp. 1643-1653
-
-
Burrow, M.P.1
Gray, G.W.2
Lacey, D.3
Toyne, K.J.4
-
23
-
-
0028386366
-
-
(b) Wong, J.; Masson, P.; Nicoud, J.-F. Polym. Bull. 1994, 32, 265-272.
-
(1994)
Polym. Bull.
, vol.32
, pp. 265-272
-
-
Wong, J.1
Masson, P.2
Nicoud, J.-F.3
-
24
-
-
18244408785
-
-
(c) Vasconcelos, U. B.; Dalmolin, E.; Merlo, A. A. Org. Lett. 2005, 7, 1027-1030.
-
(2005)
Org. Lett.
, vol.7
, pp. 1027-1030
-
-
Vasconcelos, U.B.1
Dalmolin, E.2
Merlo, A.A.3
-
25
-
-
33845280917
-
-
For references on the selective functionalization of polyhalopyridines in solution phase, see: (a) Tilley J. F.; Zawoiski, S. J. Org. Chem. 1988, 53, 386-387.
-
(1988)
J. Org. Chem.
, vol.53
, pp. 386-387
-
-
Tilley, J.F.1
Zawoiski, S.2
-
26
-
-
0035832066
-
-
(b) Belfrekh, N.; Dietrich-Buchecker, C.; Sauvage, J.-P. Tetrahedron Lett. 2001, 42, 2779-2781.
-
(2001)
Tetrahedron Lett.
, vol.42
, pp. 2779-2781
-
-
Belfrekh, N.1
Dietrich-Buchecker, C.2
Sauvage, J.-P.3
-
27
-
-
0037131349
-
-
(c) Barry, P. R.; Wang, C.; Batsanov, A. S.; Bryce, M. R.; Tarbit, B. J. Org. Chem. 2002, 67, 7541-7543.
-
(2002)
J. Org. Chem.
, vol.67
, pp. 7541-7543
-
-
Barry, P.R.1
Wang, C.2
Batsanov, A.S.3
Bryce, M.R.4
Tarbit, B.5
-
28
-
-
0347411081
-
-
(d) Ji, J.; Li, T.; Bunnelle, W. H. Org. Lett. 2003, 5, 4611-4614.
-
(2003)
Org. Lett.
, vol.5
, pp. 4611-4614
-
-
Ji, J.1
Li, T.2
Bunnelle, W.H.3
-
29
-
-
18244408785
-
-
(e) Vasconcelos, U. B.; Dalmolin, E.; Merlo, A. A. Org. Lett. 2005, 7, 1027-1030.
-
(2005)
Org. Lett.
, vol.7
, pp. 1027-1030
-
-
Vasconcelos, U.B.1
Dalmolin, E.2
Merlo, A.A.3
-
30
-
-
15444375711
-
-
(f) Heckmann, G.; Bach, T. Angew. Chem., Int. Ed. 2005, 44, 1199-1201.
-
(2005)
Angew. Chem., Int. Ed.
, vol.44
, pp. 1199-1201
-
-
Heckmann, G.1
Bach, T.2
-
33
-
-
0000996311
-
-
(c) Hu, Y.; Porco, J. A.; Labadie, J. W.; Gooding, O. W.; Trost, B. M. J. Org. Chem. 1998, 63, 4518-4521.
-
(1998)
J. Org. Chem.
, vol.63
, pp. 4518-4521
-
-
Hu, Y.1
Porco, J.A.2
Labadie, J.W.3
Gooding, O.W.4
Trost, B.M.5
-
34
-
-
0001763203
-
-
(d) Lindsley, C. W.; Hodges, J. C.; Filzen, G. F.; Watson, B. M.; Geyer, A. G. J. Comb. Chem. 2000, 2, 550-559.
-
(2000)
J. Comb. Chem.
, vol.2
, pp. 550-559
-
-
Lindsley, C.W.1
Hodges, J.C.2
Filzen, G.F.3
Watson, B.M.4
Geyer, A.G.5
-
35
-
-
0037136163
-
-
(e) Meloni, M.; Brown, R. C. D.; White, P. D.; Armour, D. Tetrahedron Lett. 2002, 43, 6023-6026.
-
(2002)
Tetrahedron Lett.
, vol.43
, pp. 6023-6026
-
-
Meloni, M.1
Brown, R.C.D.2
White, P.D.3
Armour, D.4
-
36
-
-
28244493409
-
-
note
-
All the functionalization steps were easily monitored by IR spectroscopy.
-
-
-
-
37
-
-
8644283612
-
-
This reaction was recently reported by us using the less sterically hindered TMSCl as electrophile. See: Pierrat, Ph.; Gros, Ph.; Fort, Y. Synlett, 2004, 13, 2319-2322.
-
(2004)
Synlett
, vol.13
, pp. 2319-2322
-
-
Pierrat, P.1
Gros, P.2
Fort, Y.3
-
38
-
-
28244453208
-
-
note
-
No product resulting from bromine scrambling was detected, indicating the stability of the lithio intermediate during the immobilization step. The amount of isolated 1 was in full agreement with elemental analysis.
-
-
-
-
39
-
-
0000342939
-
-
Such a dimethylamination of chloropyridine has been reported in the presence of DMF and ethanolamines. See: Cho, Y. H.; Park, J. C. Tetrahedron Lett. 1997, 38, 8331-8334.
-
(1997)
Tetrahedron Lett.
, vol.38
, pp. 8331-8334
-
-
Cho, Y.H.1
Park, J.C.2
-
40
-
-
28244496125
-
-
(Kuraray Co., Ltd., Japan). PCT Int. Appl. WO19980319 A1, 1998
-
Kuwayama, T.; Inoue, S.; Asanuma, G.; Shiono, M. (Kuraray Co., Ltd., Japan). PCT Int. Appl. WO19980319 A1, 1998; Chem. Abstr. 128, 230248.
-
Chem. Abstr.
, vol.128
, pp. 230248
-
-
Kuwayama, T.1
Inoue, S.2
Asanuma, G.3
Shiono, M.4
-
41
-
-
28244456473
-
-
note
-
Commercially available compound mp obtained from the Aldrich Advancing Science Catalog.
-
-
-
-
42
-
-
0036532565
-
-
Bouillon, A.; Lancelot, J.-C.; Rault, S. Tetrahedron 2002, 58, 2885-2890.
-
(2002)
Tetrahedron
, vol.58
, pp. 2885-2890
-
-
Bouillon, A.1
Lancelot, J.-C.2
Rault, S.3
-
43
-
-
76349119731
-
-
Bolm, C.; Ewald, M.; Felden, M.; Schlingloff, G. Chem. Ber. 1992, 125, 1169-1190.
-
(1992)
Chem. Ber.
, vol.125
, pp. 1169-1190
-
-
Bolm, C.1
Ewald, M.2
Felden, M.3
Schlingloff, G.4
-
45
-
-
0344835674
-
-
Novak, Z.; Szabo, A.; Repasi, J.; Kotschy, A. J. Org. Chem. 2003, 68, 3327-3329.
-
(2003)
J. Org. Chem.
, vol.68
, pp. 3327-3329
-
-
Novak, Z.1
Szabo, A.2
Repasi, J.3
Kotschy, A.4
-
46
-
-
0035177201
-
-
Schubert, T.; Hummel, W.; Kula, M.-R.; Muller, M. Eur. J. Org. Chem. 2001, 4181-4187.
-
(2001)
Eur. J. Org. Chem.
, pp. 4181-4187
-
-
Schubert, T.1
Hummel, W.2
Kula, M.-R.3
Muller, M.4
-
47
-
-
28244484893
-
-
(Ajinomoto Co., Inc., Japan). PCT Int. Appl. WO 19980723, 1998
-
Takayanagi, M.; Sagi, K.; Nakagawa, T.; Yamanashi, M.; Kayahara, T.; Takehana, S. (Ajinomoto Co., Inc., Japan). PCT Int. Appl. WO 19980723, 1998; Chem. Abstr. 129, 161414.
-
Chem. Abstr.
, vol.129
, pp. 161414
-
-
Takayanagi, M.1
Sagi, K.2
Nakagawa, T.3
Yamanashi, M.4
Kayahara, T.5
Takehana, S.6
-
49
-
-
4043076448
-
-
Berthiol, F.; Kondolff, I.; Doucet, H.; Santelli, M. J. Organomet. Chem. 2004, 689 (17), 2786-2798.
-
(2004)
J. Organomet. Chem.
, vol.689
, Issue.17
, pp. 2786-2798
-
-
Berthiol, F.1
Kondolff, I.2
Doucet, H.3
Santelli, M.4
-
50
-
-
37049083092
-
-
Kagabu, S.; Ando, C.; Ando, J. J. Chem. Soc., Perkin Trans. 1 1994, 6, 739-752.
-
(1994)
J. Chem. Soc., Perkin Trans. 1
, vol.6
, pp. 739-752
-
-
Kagabu, S.1
Ando, C.2
Ando, J.3
-
51
-
-
0347784714
-
-
Yanagida, S.; Ogata, T.; Kuwana, Y.; Wada, Y.; Murakoshi, K.; Ishida, A.; Takamuku, S.; Kusaba, M.; Nakashima, N. J. Chem. Soc., Perkin Trans. 2, 1996, 9, 1963-1969.
-
(1996)
J. Chem. Soc., Perkin Trans. 2
, vol.9
, pp. 1963-1969
-
-
Yanagida, S.1
Ogata, T.2
Kuwana, Y.3
Wada, Y.4
Murakoshi, K.5
Ishida, A.6
Takamuku, S.7
Kusaba, M.8
Nakashima, N.9
-
52
-
-
0346307207
-
-
Marri, E.; Pannacci, D.; Galiazzo, G.; Mazzucato, U.; Spalletti, A. J. Phys. Chem. A 2003, 107, 11231-11238.
-
(2003)
J. Phys. Chem. A
, vol.107
, pp. 11231-11238
-
-
Marri, E.1
Pannacci, D.2
Galiazzo, G.3
Mazzucato, U.4
Spalletti, A.5
-
53
-
-
84985163685
-
-
Siegrist, A.; Meyer, H. R.; Gassman, P.; Moss, S. Helv. Chim. Acta 1980, 63, 1131-1334.
-
(1980)
Helv. Chim. Acta
, vol.63
, pp. 1131-1334
-
-
Siegrist, A.1
Meyer, H.R.2
Gassman, P.3
Moss, S.4
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