The Seiji Memorial Lecture - The melanosome: An ideal model to study cellular differentiation

Pigment Cell Research

Volumn 16, Issue 3, 2003, Pages 237-244

  Kushimoto, Tsuneto ^a   Valencia, Julio C ^a   Costin, Gertrude E ^a   Toyofuku, Kazutomo ^a   Watabe, Hidenori ^a   Yasumoto, Ken Ichi ^a   Rouzaud, Francois ^a   Vieira, Wilfred D ^a   Hearing, Vincent J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Biogenesis; Melanosome; Pigmentation; Proteomics

Indexed keywords

ANIMAL CELL; BIOGENESIS; CELL DIFFERENTIATION; CELL FUNCTION; CONFERENCE PAPER; GENE DISRUPTION; GENETICS; MAMMAL CELL; MELANOSOME; MODEL; MOLECULAR BIOLOGY; NONHUMAN; OCULOCUTANEOUS ALBINISM; PIGMENT DISORDER; PIGMENTATION; PROTEIN TARGETING; PROTEOMICS;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; HUMANS; MELANINS; MELANOCYTES; MELANOSOMES; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; MONOPHENOL MONOOXYGENASE; ORGANELLES; PIGMENTATION; PROTEOME;

ANIMALIA; MAMMALIA;

EID: 0037902561     PISSN: 08935785     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0749.2003.00034.x     Document Type: Conference Paper

References (49)

1. Swank RT, Novak EK, McGarry MP, Rusiniak ME, Feng L. Mouse models of Hermansky Pudlak syndrome: a review. Pigment Cell Res 1998;11:60-80
2. Huizing M, Anikster Y, Gahl WA. Hermansky-Pudlak syndrome and related disorders of organelle formation. Traffic 2000;1:823-835
3. Spritz RA. Hermansky-Pudlak syndrome and pale ear: melanosome-making for the millennium. Pigment Cell Res 2000;13:15-20
4. Raposo G, Marks MS. The dark side of lysosome-related organelles: specialization of the endocytic pathway for melanosome biogenesis. Traffic 2002;3:237-248
5. Huizing M, Boissy RE, Gahl WA. Hermansky-Pudlak syndrome: vesicle formation from yeast to man. Pigment Cell Res 2002;15:405-419
6. Starcevic M, Nazarian R, Dell'Angelica EC. The molecular machinery for the biogenesis of lysosome-related organelles: lessons from Hermansky-Pudlak syndrome. Semin Cell Devel Biol 2002;13:271-278
7. Vijayasaradhi S, Houghton AN. Melanoma and melanocytes: pigmentation, tumor progression, and the immune response to cancer. Adv Pharmacol 1995;32:343-374
8. Engelhard VH, Bullock TNJ, Colella TA, Sheasley SL, Mullins DW. Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity and use for cancer immunotherapy. Immunol Rev 2002;188:136-146
9. Robbins PF, El-Gamil M, Li YF, Zeng G, Dudley ME, Rosenberg SA. Multiple HLA Class II-restricted melanocyte differentiation antigens are recognized by tumor-infiltrating lymphocytes from a patient with melanoma. J Immunol 2002;169:6036-6047
10. Lerner AB, Fitzpatrick TB, Calkins E, Summerson WH. Mammalian tyrosinase: preparation and properties. J Biol Chem 1949;178:185-195
11. Lerner AB, Fitzpatrick TB. Biochemistry of melanin formation. Physiol Rev 1950;30:91-126
12. Seiji M, Fitzpatrick TB, Birbeck MSC. The melanosome: a distinctive subcellular particle of mammalian melanocytes and the site of melanogenesis. J Invest Dermatol 1961;36:243-252
13. Seiji M, Shimao K, Birbeck MSC, Fitzpatrick TB. Subcellular localization of melanin biosynthesis. Ann N Y Acad Sci 1963;100:497-533
14. Kushimoto T, Basrur V, Matsunaga J, Vieira WD, Muller J, Appella E, Hearing VJ. A new model for melanosome biogenesis based on the purification and mapping of early melanosomes. Proc Natl Acad Sci USA 2001;98:10698-10703
15. Basrur V, Kushimoto T, Yasumoto K, Muller J, Vieira WD, Watabe H, Hearing VJ, Appella E. Proteomic analysis of early melanosomes: Identification of VAT-1 and Oculospanin as novel melanosomal proteins. J Prot Res 2003;2:69-79
16. King RA, Hearing VJ, Creel D, Oetting WS. Albinism. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The Metabolic and Molecular Bases of Inherited Disease, 8th edn. New York: McGraw-Hill; 2001. pp. 5587-5628
17. Oetting WS. New insights into ocular albinism type 1 (OA1): mutations and polymorphisms of the OA1 gene. Hum Mutat 2002;19:85-92
18. Haskell-Luevano C, Miwa H, Dickinson C, Hruby VJ, Yamada T, Gantz I. Binding and cAMP studies of melanocortin peptides with the cloned human peripheral melanocortin receptor, hMC1R. Biochem Biophys Res Commun 1994;204:1137-1142
19. Rees JL. The melanocortin 1 receptor (MC1R): more than just red hair. Pigment Cell Res 2000;13:135-140
20. Abdel-Malek ZA, Scott MC, Furumura M, Lamoreux ML, Ollmann M, Barsh GS, Hearing VJ. The melanocortin 1 receptor is the principal mediator of the effects of agouti signaling protein on mammalian melanocytes. J Cell Sci 2001;114:1019-1024
21. Voisey J, Box NF, van Daal A. A polymorphism study of the human agouti gene and its association with MC1R. Pigment Cell Res 2001;14:264-267
22. Bolognia J, Murray M, Pawelek JM. UVB-induced melanogenesis may be mediated through the MSH-receptor system. J Invest Dermatol 1989;92:651-656
23. Chakraborty A, Slominski A, Ermak G, Hwang J, Pawelek JM. Ultraviolet B and melanocyte-stimulating hormone (MSH) stimulate mRNA production for αMSH receptors and proopiomelanocortinderived peptides in mouse melanoma cells and transformed keratinocytes. J Invest Dermatol 1995;105:655-659
24. Furumura M, Sakai C, Abdel-Malek ZA, Barsh GS, Hearing VJ. The interaction of agouti signal protein and melanocyte stimulating hormone to regulate melanin formation in mammals. Pigment Cell Res 1996;9:191-203
25. Sakai C, Ollmann M, Kobayashi T, Abdel-Malek ZA, Muller J, Vieira WD, Imokawa G, Barsh GS, Hearing VJ. Modulation of murine melanocyte function in vitro by agouti signal protein. EMBO J 1997;16:3544-3552
26. Oetting WS. The tyrosinase gene and oculocutaneous albinism type 1 (OCAI): a model for understanding the molecular biology of melanin formation. Anonymous. Pigment Cell Res 2000;13:320-325
27. Toyofuku K, Wada I, Spritz RA, Hearing VJ. The molecular basis of oculocutaneous albinism type 1 (OCAI): sorting failure and degradation of mutant tyrosinase results in a lack of pigmentation. Biochem J 2001;355:259-269
28. Toyofuku K, Wada I, Valencia J, Hearing VJ. Oculocutaneous albinism (OCA) types 1 and 3 are ER retention diseases: mutations in tyrosinase and/or Tyrp1 influence the maturation, degradation of calnexin association of the other. FASEB J 2001;15:2149-2161
29. Toyofuku K, Valencia J, Kushimoto T, Costin GE, Virador V, Vieira WD, Ferrans VJ, Hearing VJ. The etiology of oculocutaneous albinism (OCA) type II: the pink protein controls the transport and processing of tyrosinase. Pigment Cell Res 2002;15:217-224
30. Chen K, Manga P, Orlow SJ. The pink-eyed dilution protein controls the processing of tyrosinase. Mol Biol Cell 2002;13:1953-1964
31. Costin GE, Valencia JC, Vieira WD, Lamoreux ML, Hearing VJ. Tyrosinase processing and intracellular trafficking is disrupted in mouse primary melanocytes carrying the uw mutation: a model for oculocutaneous albinism (OCA) type 4. J Cell Sci, in press
32. Brilliant MH. The mouse, p(pink-eyed dilution) and human P genes, oculocutaneous albinism type 2 (OCA2) and melanosomal pH. Pigment Cell Res 2001;14:86-93
33. Newton JM, Cohen-Barak O, Hagiwara N, Gardner JM, Davisson MT, King RA, Brilliant MH. Mutations in the human orthologue of the mouse underwhite gene (uw) underlie a new form of oculocutaneous albinism, OCA4. Am J Hum Gen 2001;69:981-988
34. Zhou BK, Boissy RE, Pifko-Hirst S, Moran DJ, Orlow SJ. Lysosome-associated membrane protein-1 (LAMP-1) is the melanocyte vesicular membrane glycoprotein band II. J Invest Dermatol 1993;100:110-114
35. Jimbow K, Park JS, Kato F, Hirosaki K, Toyofuku K, Hua C, Yamashita T. Assembly, target-signaling and intracellular transport of tyrosinase gene family proteins in the initial stage of melanosome biogenesis. Pigment Cell Res 2000;13:222-229
36. Raposo G, Tenza D, Murphy DM, Berson JF, Marks MS. Distinct protein sorting and localization to premelanosomes, melanosomes and lysosomes in pigmented melanocytic cells. J Cell Biol 2001;152:809-823
37. Puri N, Gardner JM, Brilliant MH. Aberrant pH of melanosomes in pink-eyed dilution (p) mutant melanocytes. J Invest Dermatol 2000;115:607-613
38. Ancans J, Tobin DJ, Hoogduijn MJ, Smit NP, Wakamatsu K, Thody AJ. Melanosomal pH controls rate of melanogenesis, eumelanin/phaeomelanin ratio and melanosome maturation in melanocytes and melanoma cells. Exp Cell Res 2001;268:26-35
39. Fuller BB, Spaulding DT, Smith DR. Regulation of the catalytic activity of preexisting tyrosinase in Black and Caucasian human melanocyte cell cultures. Exp Cell Res 2001;262:197-208
40. Manga P, Orlow SJ. Inverse correlation between pink-eyed dilution protein expression and induction of melanogenesis by bafilomycin Al. Pigment Cell Res 2001;14:362-367
41. Scott G, Zhao Q. Rab3a and SNARE proteins: potential regulators of melanosome movement. J Invest Dermatol 2001;116:296-304
42. Wu XS, Rao K, Zhang H, Wang F, Sellers JR, Matesic LE, Copeland NG, Jenkins NA, Hammer JA. Identification of an organelle receptor for myosin-Va. Nature Cell Biol 2002;4:271-278
43. Fukuda M, Kuroda TS, Mikoshiba K. Slac2-a/melanophilin, the missing link between Rab27 and myosin Va. J Biol Chem 2002;277:12432-12436
44. Pastural E, Barrat FJ, Dufourcq-Lagelouse R, Certain S, Sanal O, Jabado N, Seger R, Griscelli C, Fisher A, de Saint Basile G. Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene. Nature Genet 1997;16:289-292
45. Spritz RA. Multi-organellar disorders of pigmentation: tied up in traffic. Clin Genet 1999;55:309-317
46. Westbroek W, Lambert JM, Naeyaert JM. The dilute locus and Griscelli syndrome: gateways towards a better understanding of melanosome transport. Pigment Cell Res 2001;14:320-327
47. Seiji M, Iwashita S. Intracellular localization of tyrosinase in melanocytes. J Biochem 1963;54:103-106
48. Seiji M, Iwashita S. On the site of melanin formation in melanocytes. J Biochem 1963;54:465-467
49. 2+-binding phosphoprotein (p90), calnexin, on melanosomes in normal and malignant human melanocytes. Exp Cell Res 1993;209:288-300