-
1
-
-
0036810064
-
Biosensors: New approaches in drug discovery
-
Keusgen,M. (2002) Biosensors: new approaches in drug discovery. Naturwissenschaften, 89, 433-444.
-
(2002)
Naturwissenschaften
, vol.89
, pp. 433-444
-
-
Keusgen, M.1
-
2
-
-
0036469778
-
Engineered allosteric ribozymes as biosensor components
-
Breaker,R.R. (2002) Engineered allosteric ribozymes as biosensor components. Curr. Opin. Biotechnol., 13, 31-39.
-
(2002)
Curr. Opin. Biotechnol.
, vol.13
, pp. 31-39
-
-
Breaker, R.R.1
-
5
-
-
0033616774
-
Engineering precision RNA molecular switches
-
Soukup,G.A. and Breaker,R.R. (1999) Engineering precision RNA molecular switches. Proc. Natl Acad. Sci. USA, 96, 3584-3589.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 3584-3589
-
-
Soukup, G.A.1
Breaker, R.R.2
-
6
-
-
0032755647
-
Allosteric selection of ribozymes that respond to the second messengers cGMP and cAMP
-
Koizumi,M., Soukup,G.A., Kerr,J.N. and Breaker,R.R. (1999) Allosteric selection of ribozymes that respond to the second messengers cGMP and cAMP. Nature Struct. Biol., 6, 1062-1071.
-
(1999)
Nature Struct. Biol.
, vol.6
, pp. 1062-1071
-
-
Koizumi, M.1
Soukup, G.A.2
Kerr, J.N.3
Breaker, R.R.4
-
7
-
-
0034848444
-
Detection of small organic analytes by fluorescing molecular switches
-
Frauendorf,C. and Jaschke,A. (2001) Detection of small organic analytes by fluorescing molecular switches. Bioorg. Med. Chem., 9, 2521-2524.
-
(2001)
Bioorg. Med. Chem.
, vol.9
, pp. 2521-2524
-
-
Frauendorf, C.1
Jaschke, A.2
-
8
-
-
0032955410
-
In vitro selection of an allosteric ribozyme that transduces analytes to amplicons
-
Robertson,M.P. and Ellington,A.D. (1999) In vitro selection of an allosteric ribozyme that transduces analytes to amplicons. Nat. Biotechnol., 17, 62-66.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 62-66
-
-
Robertson, M.P.1
Ellington, A.D.2
-
9
-
-
0034655587
-
Design and optimization of effector-activated ribozyme ligases
-
Robertson,M.P. and Ellington,A.D. (2000) Design and optimization of effector-activated ribozyme ligases. Nucleic Acids Res., 28, 1751-1759.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 1751-1759
-
-
Robertson, M.P.1
Ellington, A.D.2
-
10
-
-
0033764406
-
RNA aptamers as pathway-specific MAP kinase inhibitors
-
Seiwert,S.D., Stines Nahreini,T., Aigner,S., Ahn,N.G. and Uhlenbeck,O.C. (2000) RNA aptamers as pathway-specific MAP kinase inhibitors. Chem. Biol., 7, 833-843.
-
(2000)
Chem. Biol.
, vol.7
, pp. 833-843
-
-
Seiwert, S.D.1
Stines Nahreini, T.2
Aigner, S.3
Ahn, N.G.4
Uhlenbeck, O.C.5
-
11
-
-
0036022522
-
Monitoring post-translational modification of proteins with allosteric ribozymes
-
Vaish,N.K., Dong,F., Andrews,L., Schweppe,R.E., Ahn,N.G., Blatt,L. and Seiwert,S.D. (2002) Monitoring post-translational modification of proteins with allosteric ribozymes. Nat. Biotechnol., 20, 810-815.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 810-815
-
-
Vaish, N.K.1
Dong, F.2
Andrews, L.3
Schweppe, R.E.4
Ahn, N.G.5
Blatt, L.6
Seiwert, S.D.7
-
12
-
-
0035070585
-
Immobilized RNA switches for the analysis of complex chemical and biological mixtures
-
Seetharaman,S., Zivarts,M., Sudarsan,N. and Breaker,R.R. (2001) Immobilized RNA switches for the analysis of complex chemical and biological mixtures. Nat. Biotechnol., 19, 336-341.
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 336-341
-
-
Seetharaman, S.1
Zivarts, M.2
Sudarsan, N.3
Breaker, R.R.4
-
13
-
-
0028472621
-
Inventing and improving ribozyme function: Rational design versus iterative selection methods
-
Breaker,R.R. and Joyce,G.F. (1994) Inventing and improving ribozyme function: rational design versus iterative selection methods. Trends Biotechnol., 12, 268-275.
-
(1994)
Trends Biotechnol.
, vol.12
, pp. 268-275
-
-
Breaker, R.R.1
Joyce, G.F.2
-
14
-
-
0031171217
-
Rational design of allosteric ribozymes
-
Tang,J. and Breaker,R.R. (1997) Rational design of allosteric ribozymes. Chem Biol, 4, 453-459.
-
(1997)
Chem. Biol.
, vol.4
, pp. 453-459
-
-
Tang, J.1
Breaker, R.R.2
-
15
-
-
0000917638
-
In vitro selection of catalytic polynucleotides
-
Breaker,R.R. (1997) In vitro selection of catalytic polynucleotides. Chem. Rev., 97, 371-390.
-
(1997)
Chem. Rev.
, vol.97
, pp. 371-390
-
-
Breaker, R.R.1
-
16
-
-
0023221419
-
A small catalytic oligoribonucleotide
-
Uhlenbeck,O.C. (1987) A small catalytic oligoribonucleotide. Nature, 328, 596-600.
-
(1987)
Nature
, vol.328
, pp. 596-600
-
-
Uhlenbeck, O.C.1
-
17
-
-
0024291288
-
Simple RNA enzymes with new and highly specific endoribonuclease activities
-
Haseloff,J. and Gerlach,W.L. (1988) Simple RNA enzymes with new and highly specific endoribonuclease activities. Nature, 334, 585-591.
-
(1988)
Nature
, vol.334
, pp. 585-591
-
-
Haseloff, J.1
Gerlach, W.L.2
-
18
-
-
0023663396
-
Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites
-
Forster,A.C. and Symons,R.H. (1987) Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites. Cell, 49, 211-220.
-
(1987)
Cell
, vol.49
, pp. 211-220
-
-
Forster, A.C.1
Symons, R.H.2
-
19
-
-
0021103442
-
A simple method for the estimation of amino groups on insoluble matrix beads
-
Antoni,G., Presentini,R., Neri P. (1983) A simple method for the estimation of amino groups on insoluble matrix beads. Anal. Biochem., 129, 60-63.
-
(1983)
Anal. Biochem.
, vol.129
, pp. 60-63
-
-
Antoni, G.1
Presentini, R.2
Neri, P.3
-
21
-
-
25044444530
-
High-affinity nucleic acids that discriminate against caffeine
-
US Patent 5, 580, 737
-
Polisky,B., Jenison,R.D. and Gold,L. (1995) High-affinity nucleic acids that discriminate against caffeine. US Patent 5, 580, 737.
-
(1995)
-
-
Polisky, B.1
Jenison, R.D.2
Gold, L.3
-
22
-
-
0034640131
-
Altering molecular recognition of RNA aptamers by-allosteric selection
-
Soukup,G.A., Emilsson,G.A. and Breaker,R.R. (2000) Altering molecular recognition of RNA aptamers by-allosteric selection. J. Mol. Biol., 298, 623-632.
-
(2000)
J. Mol. Biol.
, vol.298
, pp. 623-632
-
-
Soukup, G.A.1
Emilsson, G.A.2
Breaker, R.R.3
-
23
-
-
0035312243
-
Cooperative binding of effectors by an allosteric ribozyme
-
Jose,A.M., Soukup,G.A. and Breaker,R.R. (2001) Cooperative binding of effectors by an allosteric ribozyme. Nucleic Acids Res., 29, 1631-1637.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 1631-1637
-
-
Jose, A.M.1
Soukup, G.A.2
Breaker, R.R.3
-
24
-
-
0035989643
-
Protein-dependent ribozymes report molecular interactions in real time
-
Hartig,J.S., Najafi-Shoushtari,S.H., Grune,I., Yan,A., Ellington,A.D. and Famulok,M. (2002) Protein-dependent ribozymes report molecular interactions in real time. Nat. Biotechnol., 20, 717-722.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 717-722
-
-
Hartig, J.S.1
Najafi-Shoushtari, S.H.2
Grune, I.3
Yan, A.4
Ellington, A.D.5
Famulok, M.6
-
25
-
-
0036849338
-
A versatile communication module for controlling RNA folding and catalysis
-
Kertsburg,A. and Soukup,G.A. (2002) A versatile communication module for controlling RNA folding and catalysis. Nucleic Acids Res., 30, 4599-4606.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 4599-4606
-
-
Kertsburg, A.1
Soukup, G.A.2
-
26
-
-
0035161011
-
Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology
-
Jenne,A., Hartig,J.S., Piganeau,N., Tauer,A., Samarsky,D.A., Green,M.R., Davies,J. and Famulok,M. (2001) Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology. Nat. Biotechnol., 19, 56-61.
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 56-61
-
-
Jenne, A.1
Hartig, J.S.2
Piganeau, N.3
Tauer, A.4
Samarsky, D.A.5
Green, M.R.6
Davies, J.7
Famulok, M.8
-
27
-
-
0028224199
-
High-resolution molecular discrimination by RNA
-
Jenison,R.D., Gill,S.C., Pardi,A. and Polisky,B. (1994) High-resolution molecular discrimination by RNA. Science, 263, 1425-1429.
-
(1994)
Science
, vol.263
, pp. 1425-1429
-
-
Jenison, R.D.1
Gill, S.C.2
Pardi, A.3
Polisky, B.4
-
28
-
-
0036795275
-
A biosensor for theophylline based on fluorescence detection of ligand-induced hammerhead ribozyme cleavage
-
Sekella,P.T., Rueda,D. and Walter,N.G. (2002) A biosensor for theophylline based on fluorescence detection of ligand-induced hammerhead ribozyme cleavage. RNA, 8, 1242-1252.
-
(2002)
RNA
, vol.8
, pp. 1242-1252
-
-
Sekella, P.T.1
Rueda, D.2
Walter, N.G.3
-
29
-
-
0642367619
-
Group 1 aptazymes as genetic regulatory switches
-
Thompson,K.M., Syrett,H.A., Knudsen,S.M. and Ellington,A.D. (2002) Group 1 aptazymes as genetic regulatory switches. BMC Biotechnol., 2, 21.
-
(2002)
BMC Biotechnol.
, vol.2
, pp. 21
-
-
Thompson, K.M.1
Syrett, H.A.2
Knudsen, S.M.3
Ellington, A.D.4
-
30
-
-
1942477473
-
ADP-specific sensors enable universal assay of protein kinase activity
-
in press
-
Srinivasan,J., Cload,S., Hamaguchi,N., Kurz,J., Keene,S., Kurz,M., Boomer,R., Blanchard,J., Epstein,D., Wilson,C. and Diener,J. (2004) ADP-specific sensors enable universal assay of protein kinase activity. Chem. Biol., in press.
-
(2004)
Chem. Biol.
-
-
Srinivasan, J.1
Cload, S.2
Hamaguchi, N.3
Kurz, J.4
Keene, S.5
Kurz, M.6
Boomer, R.7
Blanchard, J.8
Epstein, D.9
Wilson, C.10
Diener, J.11
-
31
-
-
0042819938
-
Modified DNA aptamers against sweet agent aspartame
-
Saitoh,H., Nakamura,A., Kuwahara,M., Ozaki,H. and Sawai,H. (2002) Modified DNA aptamers against sweet agent aspartame. Nucleic Acids Res., Suppl., 215-216.
-
(2002)
Nucleic Acids Res.
, Issue.SUPPL.
, pp. 215-216
-
-
Saitoh, H.1
Nakamura, A.2
Kuwahara, M.3
Ozaki, H.4
Sawai, H.5
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