Controlled recovery of the transcription of nanoparticle-bound DNA by intracellular concentrations of glutathione

Bioconjugate Chemistry

Volumn 16, Issue 6, 2005, Pages 1356-1359

  Han, Gang ^a   Chari, Nandini S ^a,b   Verma, Ayush ^a   Hong, Rui ^a   Martin, Craig T ^a   Rotello, Vincent M ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MONOLAYERS; NANOPARTICLES; PEPTIDES; RNA; TRANSCRIPTION;

DNA TRANSCRIPTIONS; DOSE-DEPENDENT; FUNCTIONALIZED; GLUTHATHIONE; INTRACELLULAR CONCENTRATION; MIXED MONOLAYERS; MONOLAYER PROTECTED CLUSTERS; POSITIVELY CHARGED; RELEASE PROCESS; T7 RNA POLYMERASE;

DNA;

DNA; GLUTATHIONE; NANOPARTICLE; RNA; RNA POLYMERASE;

ARTICLE; BACTERIOPHAGE T7; CONCENTRATION RESPONSE; DNA BINDING; DNA TRANSCRIPTION; DNA TRANSFECTION; DNA VECTOR; ELECTRICITY; GENE CONTROL; GENE VECTOR; MOLECULAR INTERACTION; RNA SYNTHESIS; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION;

EID: 27944474791     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc050173j     Document Type: Article

References (31)

1. Cao, Y. W. C., Jin, R. C., and Mirkin, C. A. (2002) Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection. Science 297, 1536-1540.
2. 2+ complexes of synthetic heptapeptides as artificial nucleases. J. Am. Chem. Soc. 123, 3169-3170.
3. Dervan, P. B. (2001) Molecular recognition of DNA by small molecules. Bioorg. Med. Chem. 9, 2215-2235.
4. Seeman, N. C. (2003) DNA in a material world. Nature 421, 427-431.
5. Verma, A., and Rotello, V. M. (2005) Surface recognition of biomacromolecules using nanoparticle receptors. Chem. Commun. 303-312.
6. Nam, J. M., Stoeva, S. I., and Mirkin, C. A. (2004) Bio-bar-code-based DNA detection with PCR-like sensitivity. J. Am. Chem. Soc. 126, 5932-5933.
7. Gniazdowski, M., Denny, W. A., Nelson, S. M., and Czyz, M. (2003) Transcription factors as targets for DNA-interacting drugs. Curr. Med. Chem. 10, 909-924.
8. Demeneix, B., Hassani, Z., and Behr, J. P. (2004) Towards multifunctional synthetic vectors. Curr. Gene Ther. 4, 445-455.
9. Becerril, H. A., Stoltenberg, R. M., Wheeler, D. R., Davis, R. C., Harb, J. N., and Woolley, A. T. (2005) DNA-templated three-branched nanostructures for nanoelectronic devices. J. Am. Chem. Soc. 127, 2828-2829.
10. Liu, Y. M., Wenning, L., Lynch, M., and Reineke, T. M. (2004) New poly(D-glucaramidoamine)s induce DNA nanoparticle formation and efficient gene delivery into mammalian cells. J. Am. Chem. Soc. 126, 7422-7423.
11. Gershon, D. (1990) Human Gene-Therapy - Anticancer Trials Surprise Approval. Nature 346, 497-497.
12. Ohndorf, U. M., Rould, M. A., He, Q., Pabo, C. O., and Lippard, S. J. (1999) Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins. Nature 399, 708-712.
13. Gottesfeld, J. M., and Barbas, C. F. (2003) RNA as a transcriptional activator. Chem. Biol. 10, 584-585.
14. Krock, L., and Heckel, A. (2005) Photoinduced transcription by using temporarily mismatched caged oligonucleotides. Angew. Chem., Int. Ed. 44, 471-473.
15. Wiethoff, C. M., and Middaugh, C. R. (2003) Barriers to nonviral gene delivery. J. Pharm. Sci. 92, 203-217.
16. Nagasaki, T., Taniguchi, A., and Tamagaki, S. (2003) Photoenhancement of transfection efficiency using novel cationic lipids having a photocleavable spacer. Bioconjugate Chem. 14, 513-516.
17. Venugopalan, P., Jain, S., Sankar, S., Singh, P., Rawat, A., and Vyas, S. P. (2002) pH-Sensitive liposomes: mechanism of triggered release to drug and gene delivery prospects. Pharmazie. 57, 659-671.
18. Gopin, A., Rader, C., and Shabat, D. (2004) New chemical adaptor unit designed to release a drug from a tumor targeting device by enzymatic triggering. Bioorg. Med. Chem. 12, 1853-1858.
19. Luo, D., and Saltzman, W. M. (2000) Enhancement of transfection by physical concentration of DNA at the cell surface. Nat. Biotechnol. 18, 893-895.
20. Meister, A., Anderson, M. E. Annu. Rev. Biochem. 1983, 52, 711-760.
21. Hassan, S. S. M., and Rechnitz, G. A. (1982) Determination Of Glutathione And Glutathione-Reductase With A Silver Sulfide Membrane-Electrode. Anal. Chem. 54, 1972-1976.
22. Jones, D. P., Carlson, J. L., Samiec, P. S., Sternberg, P., Mody, V. C., Reed, R. L., and Brown, L. A. S. (1998) Glutathione measurement in human plasma Evaluation of sample collection, storage and derivatization conditions for analysis of dansyl derivatives by HPLC. Clin. Chim. Acta 275, 175-184.
23. Anderson, M. E. (1998) Glutathione: an overview of biosynthesis and modulation. Chem.-Biol. Interact. 112, 1-14.
24. Sandhu, K. K., McIntosh, C. M., Simard, J. M., Smith, S. W., and Rotello, V. M. (2002) Gold nanoparticle-mediated Transfection of mammalian cells. Bioconjugate Chem. 13, 3-6.
25. Goodman, C. M., McCusker, C. D., Yilmaz, T., and Rotello, V. M. (2004) Toxicity of gold nanoparticles functionalized with cationic and anionic side chains. Bioconjugate Chem. 15, 897-900.
26. Schaaff, T. G., Knight, G., Shafigullin, M. N., Borkman, R. F., and Whetten, R. L. (1998) Isolation and selected properties of a 10.4 kDa Gold: Glutathione cluster compound. J. Phys. Chem. B. 102, 10643-10646.
27. Verma, A., Simard, J. M., Worrall, J. W. E., and Rotello, V. M. (2004) Tunable reactivation of nanoparticle-inhibited beta-galactosidase by glutathione at intracellular concentrations. J. Am. Chem. Soc. 126, 13987-13991.
28. McIntosh, C. M., Esposito, E. A., Boal, A. K., Simard, J. M., Martin, C. T., and Rotello, V. M. (2001) Inhibition of DNA transcription using cationic mixed monolayer protected gold clusters. J. Am. Chem. Soc. 123, 7626-7629.
29. Ingram, R. S., Hostetler, M. J., and Murray, R. W. (1997) Poly-hetero-omega-functionalized alkanethiolate-stabilized gold cluster compounds. J. Am. Chem. Soc. 119, 9175-9178.
30. Kwon, D. S., Lin, C. H., Chen, S. J., Coward, J. K., Walsh, C. T., and Bollinger, J. M. (1997) Dissection of glutathionyl-spermidine synthetase/amidase from Escherichia coli into autonomously folding and functional synthetase and amidase domains. J. Biol. Chem. 272, 2429-2436.
31. Wang, Z. X., Kanaras, A. G., Bates, A. D., Cosstick, R., and Brust, M. (2004) Enzymatic DNA processing on gold nanoparticles. J. Mater. Chem. 14, 578-580.