Dreaming and schizophrenia: A common neurobiological background

Sleep and Biological Rhythms

Volumn 3, Issue 2, 2005, Pages 64-74

  Gottesmann, Claude ^a,b  

^a UNIVERSITÉ CÔTE D'AZUR   (France)

^b Valrose   (France)

Author keywords

Disconnection; Disinhibition; Glutamate; Monoamines; REM sleep

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; ADENYLATE CYCLASE; DOPAMINE; GLUTAMIC ACID; HISTAMINE; LEVODOPA; MONOAMINE; NORADRENALIN; SEROTONIN; SEROTONIN 1A RECEPTOR; SEROTONIN 1B AGONIST; SEROTONIN 2 RECEPTOR; SEROTONIN 2B RECEPTOR; SEROTONIN 2C RECEPTOR;

BRAIN BLOOD FLOW; BRAIN TOMOGRAPHY; DREAMING; ELECTROPHYSIOLOGY; HUMAN; NEUROBIOLOGY; NEUROCHEMISTRY; NUCLEUS ACCUMBENS; PARKINSON DISEASE; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; REM SLEEP; REVIEW; SCHIZOPHRENIA;

EID: 27844540481     PISSN: 14469235     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1479-8425.2005.00164.x     Document Type: Review

References (166)

1. Aserinsky E, Kleitman N. Regularly occurring periods of eye motility, and concomitant phenomena during sleep. Science 1953; 118: 273-4.
2. Henley K, Morrison AR. A re-evaluation of the effects of lesions of the pontine tegmentum and locus coeruleus on phenomena of paradoxical sleep in the cat. Acta Neurobiol. Exp. 1974; 34: 215-32.
3. Jouvet M, Delorme F. Locus coeruleus et sommeil paradoxal. CR Soc. Biol. 1965; 159: 895-9. (in French)
4. Jouvet M, Mounier D. Effets des lésions de la formation réticulaire pontique sur le sommeil du Chat. CR Soc. Biol. 1960; 154: 2301-5. (in French)
5. Sastre JP, Jouvet M. Oneiric behavior in cats. Physiol. Behav. 1979; 22: 979-89.
6. Mirmiran M. "Oneiric" behavior during active sleep induced by bilateral lesions of the pontine tegmentum in juvenile rats. In: Koella WP, ed. Sleep 1982. Karger: Basel, 1983, 236-9.
7. Mouret J, Delorme F. Lesions du tegmentum pontique et sommeil chez le Rat. CR Soc. Biol. 1967; 161: 1603-6. (in French)
8. Fromm E. Le langage oublié. Payot: Paris, 1953. (in French)
9. Freud S. The Interpretation of Dreams 1900. Standart Edition, Vol. 4. The Hogart Press: London, 1955; 1-338.
10. Revonsuo A. The reinterpretation of dreams: an evolutionary hypothesis of the function of dreaming. Behav. Brain Sci. 2000; 23: 877-901.
11. Gottesmann C. Neurophysiological support of consciousness during waking and sleep. Prog. Neurobiol. 1999; 59: 469-508.
12. Hobson JA, Stickgold R, Pace-Schott EF. The neuropsychology of REM sleep dreaming. Neuroreport 1998; 9: R1-14.
13. Foulkes WD. Dream reports from different stages of sleep. J. Abnorm. Soc. Psychol 1962; 65: 14-25.
14. Tracy RL, Tracy LN. Reports of mental activity from sleep stages 2 and 4. Percept. Mot. Skills 1974; 38: 647-8.
15. Cavallero C, Cicogna P, Natale V, Occhionero M, Zito A. Slow wave sleep dreaming. Sleep 1992; 15: 562-6.
16. Bosinelli M. Mind and consciousness during sleep. Brain Res. 1995; 69: 195-201.
17. Hobson JA, Pace-Schott E, Stickgold R. Dreaming and the brain: towards a cognitive neuroscience of conscious states. Behav. Brain Sci. 2000; 23: 793-842.
18. Nielsen T. Cognition in REM and NREM sleep: a review and possible reconciliation of two models of sleep mentation. Behav. Brain Sci. 2000; 23: 851-66.
19. Takeuchi T, Miyasita A, Inugami M, Yamamoto Y. Intrinsic dreams are not produced without REM sleep mechanims: evidence through elicitation of sleep onset periods. J. Sleep Res. 2001; 10: 43-52.
20. Takeuchi T, Ogilvie RD, Ferrelli AV, Murphy T, Yamamoto Y, Inugami M. Dreams are not produced without REM sleep mechanisms. Sleep Res. Online 1999; 2 (Suppl 1): 279.
21. Llinas R, Paré D. Of dreaming and wakefulness. Neuroscience 1991; 44: 521-35.
22. Edelman GM. Biologie de la Conscience. Jacob: Paris, 1992.
23. Dement W, Kleitman N. Cyclic variations in EEG during sleep and their relation to eye movements, body motility, and dreaming. Electroenceph. Clin. Neurophysiol. 1957; 9: 673-90.
24. Ribary U, Ionnides AA, Singh KD et al. Magnetic field tomography of coherent thalamocortical 40 Hz oscillations in humans. Proc. Natl. Acad. Sci. USA 1991; 88: 11037-41.
25. Llinas R, Ribary U. Coherent 40 Hz oscillation characterizes dream state in humans. Proc. Natl. Acad. Sci. USA 1993; 90: 2078-81.
26. Gross DW, Gotman J. Correlation of high-frequency oscillations with the sleep-wake cycle and cognitive activity in humans. Neuroscience 1999; 94: 1005-18.
27. Perez-Garci E, del Rio-Portilla Y, Guevara MA, Arce C, Corsi-cabrera M. Paradoxical sleep is characterized by uncoupled gamma activity between frontal and perceptual cortical regions. Sleep 2001; 24: 118-26.
28. Meyer-Lindenberg A, Poline JB, Kohn PD et al. Evidence for abnormal cortical functional connectivity during working memory in schizophrenia. Am. J. Psychiatry 2001; 158: 1809-17.
29. Peled A, Geva AB, Kremen WS, Blankfeld HM, Esfandiarfard R, Nordahl TE. Functional connectivity and working memory in schizophrenia: an EEG study. Int. J. Neurosci. 2000; 106: 47-61.
30. Young CE, Beach TG, Falkai P, Honer WG. SNAP-25 deficit and hippocampal connectivity in schizophrenia. Cereb. Cortex 1998; 8: 261-8.
31. Tononi G, Edelman GM. Schizophrenia and the mechanism of conscious integration. Brain Res. Rev. 2000; 31: 391-400.
32. Favale E, Loeb C, Manfredi M, Sacco G. Somatic afferent transmission and cortical responsiveness during natural sleep and arousal in the cat. Electroenceph. Clin. Neurophysiol. 1965; 18: 354-68.
33. Palestini M, Pisano M, Rosadini G, Rossi GF. Visual cortical responses evoked by stimulating lateral geniculate body and optic radiations in awake and sleeping cats. Exp. Neurol. 1964; 9: 17-30.
34. Arnaud C, Gandolfo G, Gottesmann C. The reactivity of the somesthetic S1 cortex during sleep and waking in the rat. Brain Res. Bull. 1979; 4: 735-40.
35. Weitzman ED, Kremen H. Auditory evoked responses during different stages of sleep in man. Electroenceph. Clin. Neurophysiol. 1965; 18: 65-70.
36. Williams HL, Tepas DI, Morlock JHC. Evoked responses to clicks and electroencephalographic stages of sleep in man. Science 1962; 138: 685-6.
37. Lara DR. Inhibitory deficit in schizophrenia is not necessarily a GABAergic deficit. Cell. Mol. Neurobiol. 2002; 22: 239-47.
38. Kisley MA, Olincy A, Robbins E et al. Sensory gating impairement associated with schizophrenia persists into REM sleep. Psychophysiology 2003; 40: 29-38.
39. Evarts EV. Temporal patterns of discharge of pyramidal tract neurons during sleep and waking in the monkey. J. Neurophysiol. 1964; 27: 152-71.
40. Demetrescu M, Demetrescu M, Iosif G. Diffuse regulation of visual thalamo-cortical responsiveness during sleep and wakefulness. Electroenceph. Clin. Neurophysiol. 1966; 20: 450-69.
41. Gottesmann C. Recherche sur la psychophysiologie du sommeil chez le Rat. Presses du Palais Royal: Paris, 1967; 1-156. (still available, in French with discussion and summary in English)
42. Gottesmann C. La psychophysiologie du sommeil. Bull. Psychol. 1970; 24: 520-8. (in French)
43. Gottesmann C. Psychophysiologie du sommeil. Ann. Psychol. 1971; 71: 451-88. (in French)
44. Maquet P, Franck G. REM sleep and amygdala. Mol. Psychiat 1997; 2: 195-6.
45. Maquet P, Peters JM, Aerts J et al. Functional neuroanatomy of human rapid-eye-movement sleep and dreaming. Nature 1996; 383: 163-6.
46. Maquet P. Functional neuroimaging of normal sleep by positon emission tomography. J. Sleep Res. 2000; 9: 207-31.
47. Nofzinger EA, Mintun MA, Wiseman MB, Kupfer J. Forebrain activation during REM sleep: an FDG PET study. Brain Res. 1997; 770: 192-201.
48. 15O PET study. Brain 1997; 120: 1173-97.
49. Lövblad KO, Thomas R, Jakob PM et al. Silent functional magnetic resonance imaging demonstrates focal activation in rapid eye movement sleep. Neurology 1999; 53: 2193-5.
50. Madsen PL, Holm S, Vorstrup S, Friberg L, Lassen NA, Wildschiodtz G. Human regional cerebral blood flow during rapid-eye-movement sleep. J. Cereb. Blood Flow Metab. 1991; 11: 502-7.
51. Bunney WE, Bunney BG. Evidence for a compromised dorsolateral prefrontal cortical parallel circuit in schizophrenia. Brain Res. Rev. 2000, 31: 138-46.
52. Lewis DA. GABAergic local circuit neurons and prefrontal cortical dysfunction in schizophrenia. Brain Res. Rev. 2000; 31: 270-6.
53. Weinberger DR, Berman KF, Zec RF. Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. 1. Regional cerebral blood flow evidence. Arch. Gen. Psychiatry 1986; 43: 114-24.
54. Satoh T. Direct cortical response and PGO spike during paradoxical sleep of the cat. Brain Res. 1971; 28: 576-8.
55. Jouvet M, Michel F, Courjon J. Sur la mise en jeu de deux mécanismes à expression électroencéphalographique différente au cours du sommeil physiologique chez le Chat. CR Acad. Sci. 1959; 248: 3043-5. (in French)
56. Callaway CW, Lydic R, Bagdoyan HA, Hobson JA. Pontogeniculooccipital waves: spontaneous visual system activity during rapid eye movement sleep. Cell. Mol. Neurobiol. 1987; 7: 105-49.
57. Michel F, Jeannerod M, Mouret J, Rechtschaffen A, Jouvet M. Sur les mécanismes de l'activité de pointes au niveau du système visuel au cours de la phase paradoxale du sommeil. CR Soc. Biol. 1964; 158: 103-6. (in French)
58. Mikiten TM, Niebyl PH, Hendley CD. EEG desynchronization during behavioral sleep associated with spike discharges from the thalamus of the cat. Fed. Proc. 1961; 20: 327.
59. Cespuglio R, Calvo JM, Musolino R, Valatx JL. Activité phasique chez le Rat. Physiol. Behav. 1977; 19: 589-96. (in French)
60. Datta S, Siwek DF, Patterson EH, Cipolloni PB. Localization of pontine PGO wave generation sites and their anatomical projections in the rat. Synapse 1998; 30: 409-23.
61. Farber J, Marks GA, Roffwarg HP. REM sleep PGO-type waves are present in the dorsal pons of the albino rat. Science 1980; 209: 615-17.
62. Kaufman LS, Morrison AR. Spontaneous and elicited PGO spikes in rats. Brain Res. 1981; 214: 61-72.
63. Gottesmann C. Données récentes sur les activités électrophysiologiques phasiques. Psychol. Franç 1967; 12: 1-14. (in French)
64. Gottesmann C. Etude sur les activités électrophysiologiques phasiques chez le Rat. Physiol. Behav. 1969; 4: 495-504. (in French)
65. Rechtschaffen A, Molinari S, Wabon R, Wincor MZ. Extraocular potentials. possible indicator of PGO activity in the human. Psychophysiology 1970; 7: 336.
66. Miyauchi S, Takino R, Fukuda H, Torii S. Electrophysiological evidence for dreaming: human cerebral potentials associated with rapid eye movements during REM sleep. Electroenceph. Clin. Neurophysiol. 1987; 66: 383-90.
67. McCarley RW, Winkelman JW, Duffy FH. Human cerebral potentials associated with REM sleep rapid eye movements: links to PGO waves and waking potentials. Brain Res. 1983; 274: 359-64.
68. Gandolfo G, Arnaud C, Gottesmann C. Transmission in the ventrobasal complex of rat during the sleep-waking cycle. Brain Res. Bull. 1980; 5: 921-7.
69. Steriade M. Ascending control of thalamic and cortical responsiveness. Int. Rev. Neurobiol. 1970; 12: 87-144.
70. Behrendt RP, Young C. Hallucinations in schizophrenia, sensori impairment and brain disease: an unified model. Behav. Brain Sci. in press.
71. Pommier J. Le langage intérieur. Denoel: Paris, 1970. (in French)
72. Jasper HH, Tessier J. Acetylcholine liberation from cerebral cortex during paradoxical (REM sleep). Science 1971; 172: 601-2.
73. Marrosu F, Portas C, Mascia MF et al. Microdialysis measurement of cortical and hippocampal acetylcholine release during sleep-wake cycle in freely moving cats. Brain Res. 1995; 671: 329-32.
74. Kurosawa M, Sato A, Sato Y. Stimulation of the nucleus basalis of Meynert increases acetylcholine release in the cerebral cortex in rats. Neurosci. Lett. 1989; 98: 45-50.
75. Steriade M, Buzsaki G. Parallel activation of thalamic and cortical neurons by brainstem and basal forebrain cholinergic systems. In: Steriade M, Biesold D, eds. Brain Cholinergic Systems. Oxford Science: Oxford, 1990, 3-62.
76. Nicoll RA, Malenka RC, Kauer JA. Functional comparison of neurotransmitter receptor subtypes in mammalian central nervous system. Physiol. Rev. 1990; 70: 513-66.
77. Frederickson RCA, Jordan LM, Phillis JW. The action of noradrenaline on cortical neurons: effects of pH. Brain Res. 1971; 35: 556-60.
78. Foote SL, Freedman R, Oliver AP. Effects of putative neurotransmitters on neuronal activity on monkey auditory cortex. Brain Res. 1975; 86: 229-42.
79. Krnjevic K, Phillis JW. Actions of certain amines on cerebral cortex neurons. Br. J. Pharmacol. 1963; 20: 471-90.
80. Manunta Y, Edeline JM. Effects of noradrenaline on frequency tuning of auditory cortex neurons during wakefulness and slow wave sleep. Eur. J. Neurosci. 1999; 11: 2134-50.
81. Nelson CN, Hoffer BJ, Chu NS, Bloom FE. Cytochemical and pharmacological studies on polysensory neurons in the primate frontal cortex. Brain Res. 1973; 62: 115-33.
82. Phillis JW, Lake N, Yarbrough G. Calcium mediation of the inhibitory effects of biogenic amines on cerebral coritical neurons. Brain Res. 1973; 53: 465-9.
83. Reader TA, Ferron A, Descarries L, Jasper HH. Modulatory role for biogenic amines in the cerebral cortex. Microiontopheric studies. Brain Res. 1979; 160: 219-29.
84. Warren RA, Dykes RW. Transient and long-lasting effects of iontophoretically administered norepinephrine on somatosensory cortical neurons in halothane-anesthetized cats. Can. J. Physiol. Pharmacol. 1996; 74: 38-57.
85. Aston-Jones G, Bloom FE. Norepinephrine-containing locus coeruleus neurons in behaving rat exhibit pronounced responses to non-noxious environmental stimuli. J. Neurosci. 1981; 1: 887-900.
86. Wang Z, McCormick DA. Control of firing mode of corticotectal and corticopontine layer V burst-generating neurons by norepinephrine, acetylcholine and 1S 3R-ACPD. J. Neurosci. 1993; 13: 2199-216.
87. Davies MF, Deisz RA, Prince DA, Peroutka SJ. Two distinct effects of 5-hydroxytryptamine on single cortical neurons. Brain Res. 1987; 423: 347-52.
88. 2-activated interneuron. Brain Res. 1990; 506: 62-9.
89. Araneda R, Andrade R. 5-hydroxytryptamine2 and 5-hydroxytryptamine 1A receptors mediate opposing responses on membrane excitability in the association cortex. Neuroscience 1991; 40: 399-412.
90. McCormick DA. Neurotransmitter actions in the thalamus and cerebral cortex and their role in neuromodulation of thalamocortical activity. Prog. Neurobiol. 1992; 39: 337-88.
91. Haas HL, Wolf P. Central actions of histamine: microiontophoretic studies. Brain Res. 1977; 122: 269-80.
92. 2 receptor agonists. Eur. J. Pharmacol. 1976; 38: 269-73.
93. Haas HL. Histamine actions in the mammalian central nervous system. In: Ganelin CR, Schwartz JC, eds. Frontiers in Histamine Research. Pergamon: Oxford, 1985; 215-34.
94. Schwartz JC, Arrang JM, Garbarg M, Pollard H, Ruat M. Histaminergic transmission in the mammalian brain. Physiol. Rev. 1991; 71: 1-51.
95. Servos P, Barke KE, Hough LB, Vanderwolf CH. Histamine does not play an essential role in electrocortical activation during waking behavior. Brain Res. 1994; 636: 98-102.
96. 3 receptor ligands and C-fos labeling in mesencephalic cats. Sleep Res. Online 1999; 2 (Suppl 1): 54.
97. Aston-Jones G, Bloom FE. Activity of norepinephrine-containing neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J. Neurosci. 1981; 1: 876-86.
98. Hobson JA, McCarley RW, Wyzinski PW. Sleep cycle oscillation: reciprocal discharge by two brainstem neuronal groups. Science 1975; 189: 55-8.
99. McGinty DJ, Harper RM. Dorsal raphe neurons: depression of firing during sleep in cats. Brain Res. 1976; 101: 569-75.
100. Rasmussen K, Heym J, Jacobs BL. Activity of serotonin-containing neurons in nucleus centralis superior of freely moving cats. Exp. Neurol. 1984; 83: 302-17.
101. 3-receptor ligands: an electrophysiological study in freely moving cats. Behav. Brain Res. 2003; 144: 227-41.
102. Vanni-Mercier G, Sakai K, Jouvet M. Neurones spécifiques de l'éveil dans l'hypothalamus postérieur. CR Acad. Sci. 1984; 298: 195-200. (in French)
103. Kavanau JL. Memory failures, dreal illusions and mental malfunction. Neuropsychobiology 2001; 44: 199-211.
104. Kelly PH. Defective inhibition of dream event memory formation: a hypothesized mechanism in the onset and progression of symptoms of schizophrenia. Brain Res. Bull. 1998; 46: 189-97.
105. Thierry AM, Blanc G, Sobel A, Stinus L, Glowinski J. Dopaminergic terminals in the rat cortex. Science 1973; 182: 499-501.
106. Hökfelt T, Ljungdahl A, Fuxe K, Johanson O. Dopamine nerve terminals in the rat limbic cortex. Aspects of the dopamine hypothesis of schizophrenia. Science 1974; 184: 177-9.
107. Beckstead RM, Domesick VB, Nauta WJ. Efferent connections of the substantia nigra and ventral tegmental area in the rat. Brain Res. 1979; 175: 191-217.
108. Berger B, Gaspar P, Verney C. Dopaminergic innervation of the cerebral cortex: unexpected differences between rodents and primates. Trends Neurosci. 1991; 14: 21-7.
109. Grobin AC, Deutch AY. Dopaminergic regulation of extracellular g-aminobutyric acid levels in the prefrontal cortex of the rat. J. Pharmacol. Exp. Ther. 1998; 285: 350-7.
110. Pirot S, Godbout R, Mantz J, Tassin JP, Glowinski J, Thierry AM. Inhibitory effects of ventral tegmental area stimulation on the activity of the prefrontal cortex neurons: evidence for the involvement of both dopaminergic and GABAergic components. Neuroscience 1992; 49: 857-65.
111. Rétaux R, Besson MJ, Penit-Soria J. Opposing effects of dopamine D2 receptor stimulation on the spontaneous and electrically-evoked release of 3H GABA on rat prefrontal cortex slices. Neuroscience 1991; 42: 61-72.
112. Abi-Dargham A, Moore H. Prefrontal DA transmission at D1 receptors and the pathology of schizophrenia. Neuroscientist 2003; 9: 404-16.
113. Otani S, Blond O, Desce JM, Crepel F. Dopamine facilitates long-term depression of glutaminergic transmission in the prefrontal cortex. Neuroscience 1998; 85: 669-76.
114. 1-type dopamine receptors enhances excitability in prefrontal cortical pyramidal neurons in a state-dependent manner. Neuroscience 2001; 104: 335-46.
115. Luciana M, Collins PF, Depue RA. Opposing role for dopamine and serotonin in the modulation of human spatial working memory functions. Cereb. Cortex 1998; 8: 218-26.
116. Miller JD, Farber J, Gatz P, Roffwarg H, German D. Activity of mesencephalic dopamine and non-dopamine neurons across stages of sleep and waking in the rat. Brain Res. 1983; 273: 133-41.
117. Trulson ME, Preussler DW. Dopamine-containing ventral tegmental area neurons in freely moving cats: activity during the sleep-waking cycle and effects of stress. Exp. Neurol. 1984; 83: 367-77.
118. Thompson DF, Pierce DR. Drug-induced nightmares. Ann. Pharmacother. 1999; 33: 93-8.
119. MacKay AV, Iversen LL, Rossor M et al. Increased brain dopamine and dopamine receptors in schizophrenia. Arch. Gen. Psychiatry 1982; 39: 991-7.
120. Buffenstein A, Heaster J, Ko P. Chronic psychotic illness from amphetamine. Am. J. Psychiatry 1999; 156: 662.
121. Grace AA. Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia. Neuroscience 1991; 41: 1-24.
122. Arnulf I, Bonnet AM, Damier P et al. Hallucinations, REM sleep and Parkinson's disease: a medical hypothesis. Neurology 2000; 55: 281-8.
123. Keating GL, Rye DB. Where you least expect it: dopamine in the pons and modulation of sleep and REM sleep. Sleep 2003; 26: 801-6.
124. Remington G, Chong SA. Conventional versus novel antipsychotics: changing concepts and clinical implications. J. Psychiatry Neurosci. 1999; 24: 431-41.
125. Andreasen NC, Flaum M, Swarze Wn Tyrrel G, Arnd S. Positive and negative symptoms in schizophrenia. Arch. Gen. Psychiatry 1990; 47: 615-21.
126. Okubo Y, Suhara T, Kobahashi K et al. Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET. Nature 1997; 385: 634-6.
127. Léna I, Muffat S, Deschaux O et al. Dreaming and schizophrenia have the same neurochemical background. J. Sleep Res. 2004; 13: 141.
128. De Saint-Hilaire Z, Orosco M, Rouch C, Python A, Nicolaidis S. Neuromodulation of the prefrontal cortex during sleep: a microdialysis study in rats. Neuroreport 2000; 11: 1619-24.
129. Takahata R, Moghaddam B. Target-specific glutamatergic regulation of dopamine neurons in the ventral tegmental area. J. Neurochem. 2000; 75: 1775-8.
130. Hobson JA, Pace-Schott EF. The cognitive neuroscience of sleep: neuronal systems, consciousness and learning. Nat. Rev. Neurosci. 2002; 3: 679-93.
131. Gottesmann C. The neurochemistry of waking and sleeping mental activity. The disinhibition-dopamine hypothesis. Psychiatry Clin. Neurosci. 2002; 56: 345-54.
132. Gottesmann C. Hypothesis for the neurophysiology of dreaming. Sleep Res. Online 2000; 3: 1-4.
133. De Villiers AS, Russel VA, Sagvolden T, Searson A, Jaffer A, Taljaard JJ. Alpha 2-adrenoceptor mediated inhibition of (3H) dopamine release from nucleus accumbens slices and monoamine levels in a rat model for attention-deficit hyperactivity disorser. Neurochem. Res. 1995; 20: 427-33.
134. Delfs JM, Zhu Y, Druhan JP, Aston-Jones GS. Origin of noradrenergic afferents to the shell subregion of the nucleus accumbens: anterograde and retrograde tract-tracing studies in the rat. Brain Res. 1998; 806: 127-40.
135. Fenik V, Marchenko V, Janssen P, davies RO, Kubin L. A5 cells are silenced when REM sleep-like signs are elicited by pontine carbachol. J. Appl. Physiol. 2002; 93: 1448-56.
136. Pothos E, Rada P, Mark GP, Hoebel BG. Dopamine microdialysis in the nucleus accumbens during acute and chronic morphine, naloxone-precipited withdrawal and clonidine treatment. Brain Res. 1991; 566: 348-50.
137. Ase AR, Reader TA, Hen R, Riad M, Descarries L. Altered serotonin and dopamine metabolism in the CNS of serotonin 5-HT (1A) or 5-HT (1B) receptor knockout mice. J. Neurochem. 2000; 75: 2415-26.
138. Shippenberg TS, Hen R, He M. Region-specific enhancement of basal extracellular and cocaine-evoked dopamine levels following constitutive deletion of the serotonin (B1) receptor. J. Neurochem. 2000; 75: 258-65.
139. Porras G, Di Matteo V, Fracasso C et al. 5-HT2A and 5-HT2C/2B receptor subtypes modulate dopamine release induced in vitro by amphetamine and morphine in both the rat nucleus accumbens and striatum. Neuropsychopharmacology 2002; 26: 311-24.
140. Chergui K, Suaud-Chagny MF, Gonon F. Non-linear relationship between impulse flow. Dopamine release and dopamine elimination in the rat in vivo. Neuroscience 1994; 62: 641-5.
141. Gonon FG. Nonlinear relationship between impulse flow and dopamine released by rat midbrain dopaminergic neurons as studied by in vivo electrochemistry. Neuroscience 1988; 24: 19-28.
142. Benoit-Marand M, Borrelli E, Gonon F. Inhibition of dopamine release via presynaptic D2 receptors: time course and functional characteristics in vivo. J. Neurosci. 2001; 21: 134-41.
143. Jackson ME, Frost AS, Moghaddam B. Stimulation of prefrontal cortex at physiologically relevant frequencies inhibits dopamine release in nucleus accumbens. J. Neurochem. 2001; 78: 920-3.
144. Brake WG, Flores G, Francis D, Meaney MJ, Srivastava LK, Gratton A. Enhanced nucleus accumbens dopamine and plasma corticosterone stress responses in adult rats with neonatal excitotoxic lesions to the medial prefrontal cortex. Neuroscience 2000; 96: 687-95.
145. Grace AA. Gating information flow within the limbic system and the pathophysiology of schizophrenia. Brain Res. Rev. 2000; 31: 330-41.
146. Gottesmann C. Each different type of mentation is supported by specific brain functioning. Behav. Brain Sci. 2000; 23: 941-3.
147. Vertes RP, Eastman KE. The case against memory consolidation in REM sleep. Behav. Brain Sci. 2000; 23: 867-76.
148. Segal M, Bloom FE. The action of norepinephrine in the rat hippocampus. III. Hippocampal cellular responses to locus coeruleus stimulation in the awake rat. Brain Res. 1976; 107: 499-551.
149. Segal M. The action of norepinephrine in the rat hippocampus. I. Iontophoretic studies. Brain Res. 1974; 72: 79-97.
150. Segal M. Regional differences in neuronal responses to 5-HT: intracellular studies in hippocampal slices. J. Physiol. Paris 1981; 77: 373-5.
151. Segal M. Potassium currents activated in hippocampal neurons by serotonin are mediated by a change in intracellular calcium concentrations. Eur. J. Pharmacol. 1990; 181: 299-301.
152. Lipska BK, Jaskiw G, Weinberger DR. Postpubertal emergence of hyperresponsiveness to stress and to amphetamine after neonatal excitotoxic hippocampal damage: a potential animal model of schizophrenia. Neuropsychopharmachology 1993; 9: 67-75.
153. Charara A, Grace AA. Dopamine receptor subtypes modulate excitatory afferents from the hippocampus and amygdala to rat nucleus accumbens neurons. Neuropsychopharmacology 2003; 28: 1412-21.
154. Chuhma N, Zhang. H, Masson J et al. Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. J. Neurosci. 2004; 24: 972-81.
155. Howland JG, Taepavarapruk P, Phillips AG. Glutamate receptor-dependent modulation of dopamine efflux in the nucleus accumbens by basolateral, but not central, nucleus of the amygdala in rats. J. Neurosci. 2002; 22: 1137-45.
156. Floresco SB, Yang CR, Phillips AG, Blaha CD. Basolateral amygdala stimulation evokes glutamate receptor-dependent dopamine efflux in the nucleus accumbens of the anesthetized rat. Eur. J. Neurosci. 1998; 10: 1241-51.
157. Solms M. Dreaming and REM sleep are controlled by different brain mechanisms. Behav. Brain Sci. 2000; 23: 843-50.
158. Reeves M, Lindholm DE, Myles PS, Fletcher H, Hunt JO. Adding ketamine to morphine for patient-controlled analgesia after major abdominal surgery: a double-blind, randomized trial. Anesth. Analg. 2001; 93: 116-20.
159. Heresco-Levy U. N-methyl-D-aspartate (NMDA) receptor-based treatment approaches in schizophrenia: the first decade. Int. J. Neuropharmacol. 2000; 3: 243-58.
160. Descarries L, Watkins KC, Lapierre Y. Noradrenergic axon terminals in the cerebral cortex of rats. III. Topometric ultrastructural analysis. Brain Res. 1977; 133: 197-222.
161. Friedman JI, Adler DN, Davis KL. The role of norepinephrine in the physiopathology of cognitive disorders: potential applications to the treatment of cognitive dysfunction in schizophrenia and Alzheimer's disease. Biol. Psychiat 1999; 46: 1243-52.
162. Linner L, Wiker C, Wadenberg ML, Schalling M, Svensson TH. Noradrenaline reuptake inhibition enhances the antipsychotic-like effect of raclopride and potentiates D2-blockade-induced dopamine release in the medial prefrontal cortex of the rat. Neuropsychopharmacology 2002; 27: 691-8.
163. Silver H, Barash I, Aharon N, Kaplan A, Poyurovsky M. Fluvoxamine augmentation of antipsychotics improves negative symptoms in psychotic chronic schizophrenic patients: a placebo-controlled study. Int. Clin. Psychopharmacol. 2000; 15: 257-61.
164. Van Hes R, Smid P, Stroomer CN et al. SL V310, a novel, potential antipsychotic, combining potent dopamine d2 receptor antagonism with serotonin reuptake inhibition. Bioorg. Med. Chem. Lett. 2003; 13: 405-8.
165. Pralong E, Magistretti P, Stoop R. Cellular perspectives on the glutamate-monoamine interactions in limbic lobe structures and their relevance for some psychiatric disorders. Prog. Neurobiol. 2002; 67: 173-202.
166. Nahum LH. The functions of dream cycles. Conn. Med. 1965; 29: 701-5.