Recent advances in heterocycle generation using the efficient Ugi multiple-component condensation reaction

Current Opinion in Drug Discovery and Development

Volumn 8, Issue 6, 2005, Pages 776-788

  Tempest, Paul A ^a  

^a Merck Research Laboratories Boston   (United States)

Author keywords

Efficient chemistry; Isocyanide; Multiple component condensation; Ugi

Indexed keywords

ALKYNE DERIVATIVE; BENZODIAZEPINE DERIVATIVE; BETA LACTAM DERIVATIVE; BIPYRIDINE DERIVATIVE; DIMETHYL SULFOXIDE; HETEROCYCLIC COMPOUND; IMINE; ISOQUINOLINE; ISOXAZOLE; N,N DIMETHYLFORMAMIDE; OXAZOLE DERIVATIVE; PIPERAZINE DERIVATIVE; QUINOLINE; QUINOLINE DERIVATIVE; TETRAFLUOROETHYLENE; TRIFLUOROACETIC ACID;

ACYLATION; AQUEOUS SOLUTION; CHIRALITY; CYCLIZATION; CYCLOADDITION; DECARBOXYLATION; DIELS ALDER REACTION; DRUG HYDROLYSIS; DRUG SYNTHESIS; ETHERIFICATION; HEATING; HECK REACTION; HIGH THROUGHPUT SCREENING; MICROWAVE RADIATION; POLYMERIZATION; REVIEW; RING CLOSING METATHESIS; ROOM TEMPERATURE; STAUDINGER REACTION;

AUTOMATION; BICYCLO COMPOUNDS, HETEROCYCLIC; CYCLIZATION; DRUG DESIGN; HETEROCYCLIC COMPOUNDS; IMIDAZOLINES; MICROWAVES; QUINOLONES; TEMPERATURE;

EID: 27844439456     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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