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Volumn 70, Issue 6, 2005, Pages 2361-2363

Microwave-assisted synthesis of isonitriles: A general simple methodology

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; IRRADIATION; MICROWAVES; SYNTHESIS (CHEMICAL);

EID: 15444377730     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo047924f     Document Type: Article
Times cited : (90)

References (43)
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    • note
    • All the reactions were performed with a self-tuneable microwave synthesizer. The MW experiments were performed in a self-tuning single mode CEM Discover Focused Synthesizer apparatus. The instrument continuously adjusted the applied wattage to maintain the desired temperature.
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    • note
    • For comparison, the reaction in Scheme 1 (entry 1) was also conducted using a preheated oil bath under otherwise identical conditions as for the microwave reaction, i.e., (sealed vial), RNHCHO, base, 100°C, 10 min. As expected, lower conversion (7%) was observed with the traditional thermal conditions as compared to that with microwave irradiation (81%, Table 1).


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