Sex differences in dopamine receptors and their relevance to ADHD

Neuroscience and Biobehavioral Reviews

Volumn 24, Issue 1, 2000, Pages 137-141

  Andersen, S L ^a   Teicher, M H ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

ADHD; Adolescence; Dopamine, D1, D2; Nucleus accumbens; Striatum; Tourette's syndrome

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR; EMONAPRIDE; FLUPENTIXOL; HALOPERIDOL; TRITIUM;

ADULTHOOD; AGE; ANIMAL TISSUE; ATTENTION DEFICIT DISORDER; CONFERENCE PAPER; CONTROLLED STUDY; CORPUS STRIATUM; DEVELOPMENT; DRUG RECEPTOR BINDING; FEMALE; GILLES DE LA TOURETTE SYNDROME; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PREFRONTAL CORTEX; PREVALENCE; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; SEX DIFFERENCE; SUBSTANCE ABUSE;

AGING; ANIMALS; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; FEMALE; MALE; NEOSTRIATUM; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, DOPAMINE; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; SEX CHARACTERISTICS;

EID: 0033985293     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0149-7634(99)00044-5     Document Type: Conference Paper

References (34)

1. Andersen S.L., Rutstein M., Benzo J.M., Hostetter J.C., Teicher M.H. Sex differences in dopamine receptor overproduction and elimination. NeuroReport. 8:1997;1495-1498.
2. Anderson J.C., Williams S., McGee R., Silva P.A. DSM-III disorders in preadolescent children: prevalence in a large sample from the general population. Archives of General Psychiatry. 44:1987;69-76.
3. Barkley R.A. A critique of current diagnostic criteria for attention deficit hyperactivity disorder: clinical and research implications. Journal of Developmental and Behavioral Pediatrics. 11:1990;343-352.
4. Bird H.R., Canino G., Rubio-Stipec M., Gould M.S., Ribera J., Sesman M., Woodbury M., Huertas-Goldman S., Pagan A., et al. Estimates of the prevalence of childhood maladjustment in a community survey in Puerto Rico. Archives of General Psychiatry. 45:1988;1120-1126.
5. Blum K., Sheridan P.J., Wood R.C., Braverman E.R., Chen T.J., Cull J.G., Comings D.E. The D2 dopamine receptor gene as a determinant of reward deficiency syndrome. Journal of the Royal Society of Medicine. 89:1996;396-400.
6. Carey M.P., Diewald L.M., Esposito F.J., Pellicano M.P., Gironi Carnevale U.A., Sergeant J.A., Papa M., Sadile A.G. Differential distribution, affinity, and plasticity of dopamine D-1 and D-2 receptors in the target sites of the mesolimbic system in an animal model of ADHD. Behavioral Brain Research. 94:1998;173-185.
7. Castellanos F.X., Giedd J.N., Marsh W.L. Quantitative morphology of the caudate nucleus in attention deficit hyperactivity disorder. Archives of General Psychiatry. 53:1996;607-616.
8. Castellanos F.X., Lau E., Tayebi N., Lee P., Long R.E., Giedd J.N., Sharp W., Marsh W.L., Walter J.M., Hamburger S.D., Ginns E.I., Rapoport J.L., Sidransky E. Lack of an association between a dopamine-4 receptor polymorphism and attention-defisit/hyperactivity disorder: genetic and brain morphometric analyses. Molecular Psychiatry. 3:1998;431-444.
9. Ernst M., Liebenauer L.L., King C., Fitzgerald G.A., Cohen R.M., Zametkin A.J. Reduced brain metabolism in hyperactive girls. Journal of the American Academy of Child and Adolescent Psychiatry. 33:1994;858-868.
10. Giedd J.N., Castellanos F.X., Casey B.J., Kozuch P., King A.C., Hamburger S.D., Rapoport J.L. Quantitative morphology of the corpus callosum in attention deficit hyperactivity disorder. American Journal of Psychiatry. 151:1994;665-669.
11. Giedd J.N., Castellanos F.X., Rajapakse J.C., Vaituzis A.C., Rapoport J.L. Sexual dimorphism of the developing human brain. Progress in Neuropsychopharmacology and Biological Psychiatry. 21:1997;1185-1201.
12. Giros M., Jaber M., Jones S.R., Wightman R.M., Caron M.G. Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature. 379:1996;606-612.
13. Gittelman R., Mannuzza S., Shenker R., Bonagura N. Hyperactive boys almost grown up; I: psychiatric status. Archives of General Psychiatry. 42:1985;937-947.
14. Huttenlocher P.R. Synaptic density in human frontal cortex-developmental changes and effects of aging. Brain Research. 163:1979;195-205.
15. Hynd G.W., Semrud-Clikeman M., Lorys A.R., Novey E.S., Eliopulos D., Lyytinen H. Corpus callosum morphology in attention deficit hyperactivity disorder: morphometric analysis with MRI. Journal of Learning Disabilities. 24:1991;141-146.
16. Hynd G.W., Hern K.L., Novey E.S., Eliopulos D., Marshall R., Gonzalez J.J., Voeller K.K. Attention deficit-hyperactivity disorder and asymmetry of the caudate nucleus. Journal of Child Neurology. 8:1993;339-347.
17. Leckman J.F., Pauls D.L., Cohen D.J. Tic Disorders. Bloom F.E., Kupfer D.J. Psychopharmacology: the fourth generation of progress. 1995;1665-1674 Raven Press, New York.
18. Lidow M.S., Goldman-Rakic P.S., Rakic P. Synchronized over production of neurotransmitter receptors in diverse regions of the primate cerebral cortex. Proceedings of the National Academy of Sciences. 88:1991;10218-10224.
19. Maldonado R., Robledo P., Chover A.J., Caine S.B., Koob G.F. D1 dopamine receptors in the nucleus accumbens modulate cocaine self-administration in the rat. Pharmacology, Biochemistry and Behavior. 45:1993;239-242.
20. Munson P., Rodbard D. LIGAND: a versatile computerized approach for characterization of ligand-binding systems. Analytical Biochemistry. 107:1980;220-239.
21. Niemegeers C.J.E., Janssen P.A. Arzneim Forsch. 24:1974;45-52.
22. Pauls D.L. Genetic factors in the expression of attention-deficit hyperactivity disorder. Journal of Child and Adolescent Psychopharmacology. 1:1991;353-360.
23. Rakic P., Bourgeois J.P., Eckenhoff M.F., Zecevic N., Goldman-Rakic P.S. Concurrent over production of synapses in diverse regions of the primate cerebral cortex. Science. 232:1986;232-234.
24. Rakic P. Development of the primate cerebral cortex. Lewis M. Child and adolescent psychiatry. 1986;Williams and Wilkins, Baltimore.
25. Rosenberg D.R., Lewis D.A. Postnatal maturation of the dopaminergic innervation of monkey prefrontal and motor cortices: A tyrosine hydroxylase immunohistochemical analysis. Journal of Comparative Neurology. 358:1995;383-400.
26. Sagvolden T., Pettersen M.B., Larsen M.C. Spontaneously hypertensive rats (SHR) as a putative animal model of childhood hyperkinesis: SHR behavior compared to four other rat strains. Physiology and Behavior. 54:1993;1047-1055.
27. Seeman P., Bzowej N., Guan H., Bergeron C., Becker L.E., Reynolds G.P., Bird E.D., Riedere P., Jellinger K., Watanabe S., Tourtellotte W.W. Human brain receptors in children and aging adults. Synapse. 1:1987;399-404.
28. Swanson J.M., Sunohara G.A., Kennedy J.L., Regino R., Fineberg E., Wigal T., Lerner M., Williams L., LaHoste G.J., Wigal S. Association of the dopamine receptor D4 (DRD4) gene with a refined phenotype of attention deficit hyperactivity disorder (ADHD): a family-based approach. Molecular Psychiatry. 3:1998;38-41.
29. Teicher M.H., Andersen S.L., Hostetter J.C. Evidence for dopamine receptor pruning between adolescence and adulthood in striatum but not nucleus accumbens. Developmental Brain Research. 89:1995;167-172.
30. Teicher M.H., Andersen S.L., Glod C.A., Navalta C.P., Gelbard H. Neuropsychiatric disorders of childhood and adolescence. Yudofsky S.C., Hales R.E. Textbook of neuropsychiatry. 3 :1997;903-941.
31. Weinberger D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Archives of General Psychiatry. 44:1987;660-669.
32. Wender P.H. The hyperactive child, adolescent, and adult: attention deficit disorder through the lifespan. 1987;Oxford University Press, New York.
33. Wolf S.S., Jones D.W., Knable M.B., Gorey J.G., Lee K.S., Hyde T.M., Coppola R., Weinberger D.R. Tourette syndrome: prediction of phenotypic variation in monozygotic twins by caudate nucleus D2 receptor binding. Science. 273:1996;1225-1227.
34. Wong D.F., Broussolle E.P., Wand G., Villemagne V., Danals R.F., Links J.M., Zacur H.A., Harris J., Naidu S., Braestrup C., Wagner W.N. Jr, Gjedde A. In vivo measurement of dopamine receptors in human brain by positron emission tomography, age and sex differences. Annals of the New York Academy of Sciences. 1987;203-214.