Suppression of inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 22(R)-hydroxycholesterol requires de novo protein synthesis in activated macrophages

Journal of Steroid Biochemistry and Molecular Biology

Volumn 97, Issue 4, 2005, Pages 376-383

  Yasuda, Toshimichi ^a,b   Kanno, Masamoto ^b   Kawamoto, Masashi ^a   Yuge, Osafumi ^a   Ninomiya, Yuichi ^b  

^a HIROSHIMA UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

22(R) Hydroxycholesterol (22R HC); Inflammation; Macrophage

Indexed keywords

22 HYDROXYCHOLESTEROL; CCAAT ENHANCER BINDING PROTEIN; CHOLESTEROL DERIVATIVE; CYCLOHEXIMIDE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DNA BINDING; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; MACROPHAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN SYNTHESIS; RAT; RNA ANALYSIS;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; CELLS, CULTURED; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DNA; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOCORTICOIDS; HYDROXYCHOLESTEROLS; INFLAMMATION; LIGANDS; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MODELS, STATISTICAL; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRITES; PROTEIN BINDING; PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RNA; RNA, MESSENGER; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 27744552599     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2005.06.030     Document Type: Article

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