Low concentrations of neuroactive steroids alter kinetics of [ 3H]ifenprodil binding to the NMDA receptor in rat frontal cortex

British Journal of Pharmacology

Volumn 146, Issue 6, 2005, Pages 894-902

  Johansson, Tobias ^a   Frändberg, Per Anders ^a   Nyberg, Fred ^a   Le Grevès, Pierre ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Allosteric modulation; Ifenprodil; Neurosteroid; NMDA receptor; NR2B subunit; Receptor binding

Indexed keywords

IFENPRODIL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PREGNANOLONE SULFATE; PREGNENOLONE SULFATE; PROTEIN SUBUNIT; RADIOLIGAND; STEROID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING KINETICS; BINDING SITE; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISSOCIATION; DRUG RECEPTOR BINDING; FRONTAL CORTEX; KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; FRONTAL LOBE; MALE; PIPERIDINES; PREGNANOLONE; PREGNENOLONE; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; TRITIUM;

EID: 27744533168     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706397     Document Type: Article

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