메뉴 건너뛰기




Volumn 126, Issue 4, 1996, Pages 323-330

The neurosteroid pregnenolone sulfate reduces learning deficits induced by scopolamine and has promnestic effects in mice performing an appetitive learning task

Author keywords

Amnesia; GABA(A) receptor; Go No Go visual discrimination; Memory; Mice; NMDA receptor; Retrieval

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PREGNENOLONE SULFATE; SCOPOLAMINE; STEROID;

EID: 0029816478     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02247383     Document Type: Article
Times cited : (70)

References (45)
  • 1
    • 0017091532 scopus 로고
    • Short-term memory in the Rhesus monkey: Disruption from the anticholinergic scopolamine
    • Bartus RT, Johnson HR (1976) Short-term memory in the Rhesus monkey: disruption from the anticholinergic scopolamine. Pharmacol Biochem Behav 5:39-46
    • (1976) Pharmacol Biochem Behav , vol.5 , pp. 39-46
    • Bartus, R.T.1    Johnson, H.R.2
  • 2
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction
    • Bartus RT, Dean RL, Beer B, Lippa AS (1982) The cholinergic hypothesis of geriatric memory dysfunction. Science 217: 408-417
    • (1982) Science , vol.217 , pp. 408-417
    • Bartus, R.T.1    Dean, R.L.2    Beer, B.3    Lippa, A.S.4
  • 3
    • 0022636674 scopus 로고
    • Patterns of memory failures after scopolamine treatment: Implications for cholinergic hypothesis of dementia
    • Beatty WW, Butters N, Janowsky DS (1986) Patterns of memory failures after scopolamine treatment: implications for cholinergic hypothesis of dementia. Behav Neural Biol 45:196-211
    • (1986) Behav Neural Biol , vol.45 , pp. 196-211
    • Beatty, W.W.1    Butters, N.2    Janowsky, D.S.3
  • 4
    • 0027155274 scopus 로고
    • Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons
    • Bowlby MR (1993) Pregnenolone sulfate potentiation of N-methyl-D-aspartate receptor channels in hippocampal neurons. Mol Pharmacol 43:813-819
    • (1993) Mol Pharmacol , vol.43 , pp. 813-819
    • Bowlby, M.R.1
  • 5
    • 0029145499 scopus 로고
    • Pregnenolone antagonizes dizocilpine amnesia: Role for allopregnanolone
    • Cheney DL, Uzunov D, Guidotti A (1995) Pregnenolone antagonizes dizocilpine amnesia: role for allopregnanolone. Neuroreport 6:1697-1700
    • (1995) Neuroreport , vol.6 , pp. 1697-1700
    • Cheney, D.L.1    Uzunov, D.2    Guidotti, A.3
  • 6
    • 0022875838 scopus 로고
    • Cholinergic function and intellectual decline in Alzheimer's disease
    • Collerton D (1986) Cholinergic function and intellectual decline in Alzheimer's disease. Neuroscience 19:1-28
    • (1986) Neuroscience , vol.19 , pp. 1-28
    • Collerton, D.1
  • 8
    • 0020686674 scopus 로고
    • Alzheimer's disease: A disorder of cortical cholinergic innervation
    • Coyle JT, Price DL, Delong MR (1983) Alzheimer's disease: a disorder of cortical cholinergic innervation. Science 219: 1184-1190
    • (1983) Science , vol.219 , pp. 1184-1190
    • Coyle, J.T.1    Price, D.L.2    Delong, M.R.3
  • 9
    • 0025972419 scopus 로고
    • Models of memory dysfunction? A comparison of the effects of scopolamine and lorazepam on memory, psychomotor performance and mood
    • Curran UV, Schifano F, Lader M (1991) Models of memory dysfunction? A comparison of the effects of scopolamine and lorazepam on memory, psychomotor performance and mood. Psychopharmacology 103:83-90
    • (1991) Psychopharmacology , vol.103 , pp. 83-90
    • Curran, U.V.1    Schifano, F.2    Lader, M.3
  • 10
    • 0026005792 scopus 로고
    • The behavioral effects of heptyl physostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents
    • Dawson GR, Bentley G, Draper F, Rycroft W, Iversen SD, Pagella PG (1991) The behavioral effects of heptyl physostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents. Pharmacol Biochem Behav 39:865-871
    • (1991) Pharmacol Biochem Behav , vol.39 , pp. 865-871
    • Dawson, G.R.1    Bentley, G.2    Draper, F.3    Rycroft, W.4    Iversen, S.D.5    Pagella, P.G.6
  • 11
    • 0026697809 scopus 로고
    • Pharmacological mechanisms and animal models of cognition
    • Dawson GR, Heyes CM, Iversen SD (1992) Pharmacological mechanisms and animal models of cognition. Behav Pharmacol 3: 285-297
    • (1992) Behav Pharmacol , vol.3 , pp. 285-297
    • Dawson, G.R.1    Heyes, C.M.2    Iversen, S.D.3
  • 12
    • 0014195425 scopus 로고
    • Amnesia induced by scopolamine and its temporal variations
    • Deutsch JA, Rocklin KW (1967) Amnesia induced by scopolamine and its temporal variations. Nature 216:89-90
    • (1967) Nature , vol.216 , pp. 89-90
    • Deutsch, J.A.1    Rocklin, K.W.2
  • 13
    • 0017652462 scopus 로고
    • Memory and cognitive function in man: Does the cholinergic system have a specific role
    • Drachmann D (1977) Memory and cognitive function in man: does the cholinergic system have a specific role. Neurology 27: 783-790
    • (1977) Neurology , vol.27 , pp. 783-790
    • Drachmann, D.1
  • 14
    • 0023896577 scopus 로고
    • Dehydroepiandrosterone sulfate improves memory in aging mice
    • Flood JF, Roberts E (1988) Dehydroepiandrosterone sulfate improves memory in aging mice. Brain Res 448: 178-181
    • (1988) Brain Res , vol.448 , pp. 178-181
    • Flood, J.F.1    Roberts, E.2
  • 15
    • 0023911026 scopus 로고
    • Dehydroepiandrosterone and its sulfate enhance memory retention in mice
    • Flood JF, Smith GE, Roberts E (1988) Dehydroepiandrosterone and its sulfate enhance memory retention in mice. Brain Res 447:269-278
    • (1988) Brain Res , vol.447 , pp. 269-278
    • Flood, J.F.1    Smith, G.E.2    Roberts, E.3
  • 16
    • 0026542895 scopus 로고
    • Memory-enhancing effects in mice of pregnenolone and steroids metabolically derived from it
    • Flood JF, Morley JE, Roberts E (1992) Memory-enhancing effects in mice of pregnenolone and steroids metabolically derived from it. Proc Natl Acad Sci USA 89: 1567-1571
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1567-1571
    • Flood, J.F.1    Morley, J.E.2    Roberts, E.3
  • 19
    • 0023856844 scopus 로고
    • Preventive effect of cholecystokinin octapeptide on scopolamine-induced memory impairment in the rat
    • Itoh S, Takashima A, Katsuura G (1988) Preventive effect of cholecystokinin octapeptide on scopolamine-induced memory impairment in the rat. Drug Dev Res 12:63-70
    • (1988) Drug Dev Res , vol.12 , pp. 63-70
    • Itoh, S.1    Takashima, A.2    Katsuura, G.3
  • 22
    • 0023808332 scopus 로고
    • Cholinergic "blockade" as a model for cholinergic depletion. A comparison of the memory deficits with those of Alzheimer type dementia and the alcoholic Korsakoff syndrome
    • Kopelman MD, Corn TH (1988) Cholinergic "blockade" as a model for cholinergic depletion. A comparison of the memory deficits with those of Alzheimer type dementia and the alcoholic Korsakoff syndrome. Brain 111:1079-1110
    • (1988) Brain , vol.111 , pp. 1079-1110
    • Kopelman, M.D.1    Corn, T.H.2
  • 23
    • 0025887068 scopus 로고
    • Cholinergic modulation of spatial learning in mice in a Morris-type water maze
    • Lamberty Y, Gower J (1991) Cholinergic modulation of spatial learning in mice in a Morris-type water maze. Arch Int Pharmacodyn Ther 309:5-19
    • (1991) Arch Int Pharmacodyn Ther , vol.309 , pp. 5-19
    • Lamberty, Y.1    Gower, J.2
  • 24
    • 0026592972 scopus 로고
    • Oxiracetam antagonizes the disruptive effects of scopolamine on memory in the radial maze
    • Magnani M, Pozzi O, Biagetti R, Banfi S, Dorigotti L (1992) Oxiracetam antagonizes the disruptive effects of scopolamine on memory in the radial maze. Psychopharmacology 106: 175-178
    • (1992) Psychopharmacology , vol.106 , pp. 175-178
    • Magnani, M.1    Pozzi, O.2    Biagetti, R.3    Banfi, S.4    Dorigotti, L.5
  • 25
    • 0026732022 scopus 로고
    • Pregnenolone sulfate increases the convulsant potency of N-methyl-D-aspartate in mice
    • Maione S, Berrino L, Vitagliano S, Leyva J, Rossi F (1992) Pregnenolone sulfate increases the convulsant potency of N-methyl-D-aspartate in mice. Eur J Pharmacol 219:477-479
    • (1992) Eur J Pharmacol , vol.219 , pp. 477-479
    • Maione, S.1    Berrino, L.2    Vitagliano, S.3    Leyva, J.4    Rossi, F.5
  • 26
    • 0023114555 scopus 로고
    • Pregnenolone sulfate: An endogenous antagonist of the γ-aminobutyric acid receptor complex in the brain?
    • Majewska MD, Schwartz RD (1987) Pregnenolone sulfate: an endogenous antagonist of the γ-aminobutyric acid receptor complex in the brain? Brain Res 404:355-360
    • (1987) Brain Res , vol.404 , pp. 355-360
    • Majewska, M.D.1    Schwartz, R.D.2
  • 27
    • 0028032491 scopus 로고
    • The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task
    • Mathis C, Paul SM, Crawley JN (1994) The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task. Psychopharmacology 116:201-206
    • (1994) Psychopharmacology , vol.116 , pp. 201-206
    • Mathis, C.1    Paul, S.M.2    Crawley, J.N.3
  • 29
    • 0027394538 scopus 로고
    • Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat
    • Mayo W, Dellu F, Robel P, Cherkaoin J, Le Moal M, Baulieu E-E, Simon H (1993) Infusion of neurosteroids into the nucleus basalis magnocellularis affects cognitive processes in the rat. Brain Res 607:324-328
    • (1993) Brain Res , vol.607 , pp. 324-328
    • Mayo, W.1    Dellu, F.2    Robel, P.3    Cherkaoin, J.4    Le Moal, M.5    Baulieu, E.-E.6    Simon, H.7
  • 30
    • 0029670384 scopus 로고    scopus 로고
    • Neurosteroids block the memory-impairing effects of ethanol in mice
    • Melchior CL, Ritzmann RF (1996) Neurosteroids block the memory-impairing effects of ethanol in mice. Pharmacol Biochem Behav 53:51-56
    • (1996) Pharmacol Biochem Behav , vol.53 , pp. 51-56
    • Melchior, C.L.1    Ritzmann, R.F.2
  • 31
    • 0027518751 scopus 로고
    • Effects of anti-CCK-8 antiserum on acquisition and retrieval by mice in an appetitive task
    • Meziane H, Devigne C, Tramu G, Soumireu-Mourat B (1993) Effects of anti-CCK-8 antiserum on acquisition and retrieval by mice in an appetitive task. Peptides 14:67-73
    • (1993) Peptides , vol.14 , pp. 67-73
    • Meziane, H.1    Devigne, C.2    Tramu, G.3    Soumireu-Mourat, B.4
  • 32
    • 0024343524 scopus 로고
    • Pregnenolone sulfate antagonizes GABA-A receptor-mediated currents via a reduction of channel opening frequency
    • Mienville J-M, Vicini S (1989) Pregnenolone sulfate antagonizes GABA-A receptor-mediated currents via a reduction of channel opening frequency. Brain Res 489:190-194
    • (1989) Brain Res , vol.489 , pp. 190-194
    • Mienville, J.-M.1    Vicini, S.2
  • 33
    • 0024818457 scopus 로고
    • Scopolamine impairs both working and reference memory in rats: A replication and extension
    • Okaichi H Oshima Y, Jarrard LE (1989) Scopolamine impairs both working and reference memory in rats: a replication and extension. Pharmacol Biochem Behav 34:599-602
    • (1989) Pharmacol Biochem Behav , vol.34 , pp. 599-602
    • Okaichi, H.1    Oshima, Y.2    Jarrard, L.E.3
  • 34
    • 0021181906 scopus 로고
    • Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood
    • Orentreich N, Brind JL, Rizer RL, Vogelman JU (1984) Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood. J Clin Endocrinol Metab 59:551-555
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 551-555
    • Orentreich, N.1    Brind, J.L.2    Rizer, R.L.3    Vogelman, J.U.4
  • 35
    • 0026579057 scopus 로고
    • Neuroactive steroids
    • Paul SM, Purdy R (1992) Neuroactive steroids. FASEB J 6: 2311-2322
    • (1992) FASEB J , vol.6 , pp. 2311-2322
    • Paul, S.M.1    Purdy, R.2
  • 36
    • 0028016083 scopus 로고
    • The central cholinergic system during aging
    • Pepeu G, Giovannelli L (1994) The central cholinergic system during aging. Prog Brain Res 100:67-71
    • (1994) Prog Brain Res , vol.100 , pp. 67-71
    • Pepeu, G.1    Giovannelli, L.2
  • 37
    • 0025651974 scopus 로고
    • Neurotransmitter changes in Alzheimer' s disease: Implications to diagnostics and therapy
    • Reinikainen KJ, Soininen H, Riekkinen PJ (1990) Neurotransmitter changes in Alzheimer' s disease: implications to diagnostics and therapy. J Neurosci Res 27:576-586
    • (1990) J Neurosci Res , vol.27 , pp. 576-586
    • Reinikainen, K.J.1    Soininen, H.2    Riekkinen, P.J.3
  • 38
    • 0028982924 scopus 로고
    • Pregnenolone: From Selye to Alzheimer and a model of the pregnenolone sulfate binding site on the GABA-A receptor
    • Roberts E (1995) Pregnenolone: From Selye to Alzheimer and a model of the pregnenolone sulfate binding site on the GABA-A receptor. Biochem Pharmacol 49[1]:1-16
    • (1995) Biochem Pharmacol , vol.49 , Issue.1 , pp. 1-16
    • Roberts, E.1
  • 39
    • 0028244499 scopus 로고
    • Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizocilpine amnesia: Putative role for allo-pregnanolone
    • Romeo E, Cheney DL, Zivkovic I, Costa E, Guidotti A (1994) Mitochondrial diazepam-binding inhibitor receptor complex agonists antagonize dizocilpine amnesia: putative role for allo-pregnanolone. J Pharmacol Exp Ther 270:89-96
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 89-96
    • Romeo, E.1    Cheney, D.L.2    Zivkovic, I.3    Costa, E.4    Guidotti, A.5
  • 40
    • 0026568853 scopus 로고
    • Memory consolidation of a habitution task: Role of N-methyl-D-aspartate cholinergic muscarinic and GABA-A receptors in different brain regions
    • Rosat R, Da-Silva RC, Zanatti MS, Medina JH, Izquierdo I (1992) Memory consolidation of a habitution task: role of N-methyl-D-aspartate cholinergic muscarinic and GABA-A receptors in different brain regions. Braz J Med Biol Res 25:267-273
    • (1992) Braz J Med Biol Res , vol.25 , pp. 267-273
    • Rosat, R.1    Da-Silva, R.C.2    Zanatti, M.S.3    Medina, J.H.4    Izquierdo, I.5
  • 41
    • 0026571391 scopus 로고
    • Memory consolidation with peripherally acting cholinergic drugs
    • Rush D, Streit K (1992) Memory consolidation with peripherally acting cholinergic drugs. Psychopharmacology 106:375-382
    • (1992) Psychopharmacology , vol.106 , pp. 375-382
    • Rush, D.1    Streit, K.2
  • 42
    • 0026465707 scopus 로고
    • D-Cycloserine a modulator of the N-methyl-D-aspartate receptor, improves spatial learning in rats treated with muscarinic antagonist
    • Sirviö J, Ekonsalo T, Riekkinen Jr P, Lahtinen H, Riekkinen Sr P (1992) D-Cycloserine a modulator of the N-methyl-D-aspartate receptor, improves spatial learning in rats treated with muscarinic antagonist. Neurosci Lett 146:215-218
    • (1992) Neurosci Lett , vol.146 , pp. 215-218
    • Sirviö, J.1    Ekonsalo, T.2    Riekkinen Jr., P.3    Lahtinen, H.4    Riekkinen Sr., P.5
  • 43
    • 0021060892 scopus 로고
    • Effects of anticholinergic drugs on learning and memory
    • Spencer DG, Lal H (1983) Effects of anticholinergic drugs on learning and memory. Drug Dev Res 3:489-502
    • (1983) Drug Dev Res , vol.3 , pp. 489-502
    • Spencer, D.G.1    Lal, H.2
  • 44
    • 0025854291 scopus 로고
    • Scopolamine- and morphine-induced impairments of spontaneous alternation performance in mice: Reversal with glucose and with cholinergic and adrenergic agonists
    • Stone WS, Walser B, Gold SD, Gold PE (1991) Scopolamine- and morphine-induced impairments of spontaneous alternation performance in mice: reversal with glucose and with cholinergic and adrenergic agonists. Behav Neurosci 105:264-271
    • (1991) Behav Neurosci , vol.105 , pp. 264-271
    • Stone, W.S.1    Walser, B.2    Gold, S.D.3    Gold, P.E.4
  • 45
    • 0025995802 scopus 로고
    • Pregnenolone sulfate: A positive allosteric modulator at the N-methyl-D-aspartate receptor
    • Wu F-S, Gibbs TT, Farb DH (1991) Pregnenolone sulfate: a positive allosteric modulator at the N-methyl-D-aspartate receptor. Mol Pharmacol 40:333-336
    • (1991) Mol Pharmacol , vol.40 , pp. 333-336
    • Wu, F.-S.1    Gibbs, T.T.2    Farb, D.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.