Functional characterization of the sea urchin sns chromatin insulator in erythroid cells

Blood Cells, Molecules, and Diseases

Volumn 35, Issue 3, 2005, Pages 339-344

  Acuto, Santina ^a   Di Marzo, Rosalba ^a   Calzolari, Roberta ^a   Baiamonte, Elena ^b   Maggio, Aurelio ^a   Spinelli, Giovanni ^b  

^a Unita di Ricerca P Cutino   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

Author keywords

Chromatin insulator; Enhancer blocking; Erythroid transcription factor; Globin enhancer

Indexed keywords

BETA GLOBULIN; CELL EXTRACT; CIS ACTING ELEMENT; DNA BINDING PROTEIN; GAMMA GLOBIN; OCTAMER TRANSCRIPTION FACTOR 1; PROTEIN ANTIBODY; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR SP1;

5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ASSAY; CELL CULTURE; CELL NUCLEUS; CHROMATIN; DNA SEQUENCE; ERYTHROID CELL; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; INSULATOR ELEMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SEA URCHIN;

ANIMALS; CELL LINE; CHROMATIN; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENHANCER ELEMENTS (GENETICS); ERYTHROID CELLS; GATA1 TRANSCRIPTION FACTOR; GENE TRANSFER TECHNIQUES; GLOBINS; HUMANS; INSULATOR ELEMENTS; LOCUS CONTROL REGION; MICE; OCTAMER TRANSCRIPTION FACTOR-1; PARACENTROTUS; SEA URCHINS; SP1 TRANSCRIPTION FACTOR;

ANIMALIA; ECHINOIDEA; PARACENTROTUS LIVIDUS;

EID: 27744521286     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcmd.2005.07.011     Document Type: Article

References (33)

1. R. Kellum, and P. Schedl A group of scs elements function as domain boundaries in an enhancer-blocking assay Mol. Cell. Biol. 12 1992 2424 2431
2. P.K. Geyer, and V.G. Corces DNA position-specific repression of transcription by a Drosophila zinc finger protein Genes Dev. 6 1992 1865 1873
3. A.C. Bell, and G. Felsenfeld Stopped at the border: boundaries and insulators Curr. Opin. Genet. Dev. 9 1999 191 198
4. T.I. Gerasimova, and V.G. Corces Boundary and insulator elements in chromosomes Curr. Opin. Genet. Dev. 6 1996 185 192
5. T.I. Gerasimova, and V.G. Corces Domains and boundaries in chromosomes Results Probl. Cell Differ. 25 1999 229 249
6. T.I. Gerasimova, and V.G. Corces Chromatin insulators and boundaries: effects on transcription and nuclear organization Annu. Rev. Genet. 35 2001 193 208
7. P.K. Geyer, and I. Clark Protecting against promiscuity: the regulatory role of insulators Cell. Mol. Life Sci. 59 2002 2112 2127
8. A.C. Bell, A.G. West, and G. Felsenfeld Insulators and boundaries: versatile regulatory elements in the eukaryotic Science 291 2001 447 450
9. A.G. West, M. Gaszner, and G. Felsenfeld Insulators: many functions, many mechanisms Genes Dev. 16 2002 271 288
10. M. Labrador, and V.G. Corces Setting the boundaries of chromatin domains and nuclear organization Cell 111 2002 151 154
11. T.M. Yusufzai, H. Tagami, Y. Nakatani, and G. Felsenfeld CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species Mol. Cell 13 2004 291 298
12. T.I. Gerasimova, K. Byrd, and V.G. Corces A chromatin insulator determines the nuclear localization of DNA Mol. Cell 6 2000 1025 1035
13. T.I. Gerasimova, D.A. Gdula, D.V. Gerasimov, O. Simonova, and V.G. Corces A Drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation Cell 82 1995 587 597
14. S.C. Elgin, and S.I. Grewal Heterochromatin: silence is golden Curr. Biol. 13 2003 R895 R898
15. M.J. Pikaart, F. Recillas-Targa, and G. Felsenfeld Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators Genes Dev. 12 1998 2852 2862
16. M.N. Prioleau, P. Nony, M. Simpson, and G. Felsenfeld An insulator element and condensed chromatin region separate the chicken beta-globin locus from an independently regulated erythroid-specific folate receptor gene EMBO J. 18 1999 4035 4048
17. D.A. Gdula, T.I. Gerasimova, and V.G. Corces Genetic and molecular analysis of the gypsy chromatin insulator of Drosophila Proc. Natl. Acad. Sci. U. S. A. 93 1996 9378 9383
18. A.G. West, S. Huang, M. Gaszner, M.D. Litt, and G. Felsenfeld Recruitment of histone modifications by USF proteins at a vertebrate barrier element Mol. Cell 16 2004 453 463
19. M.D. Litt, M. Simpson, F. Recillas-Targa, M.N. Prioleau, and G. Felsenfeld Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci EMBO J. 20 2001 2224 2235
20. V.J. Mutskov, C.M. Farrell, P.A. Wade, A.P. Wolffe, and G. Felsenfeld The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation Genes Dev. 16 2002 1540 1554
21. F. Palla, R. Melfi, L. Anello, M. Di Bernardo, and G. Spinelli Enhancer blocking activity located near the 3′ end of the sea urchin early H2A histone gene Proc. Natl. Acad. Sci. U. S. A. 94 1997 2272 2277
22. R. Melfi, F. Palla, P. Di Simone, C. Alessandro, L. Cali, L. Anello, and G. Spinelli Functional characterization of the enhancer blocking element of the sea urchin early histone gene cluster reveals insulator properties and three essential cis-acting sequences J. Mol. Biol. 304 2000 753 763
23. D. Di Caro, R. Melfi, C. Alessandro, G. Serio, V. Di Caro, V. Cavalieri, F. Palla, and G. Spinelli Down-regulation of early sea urchin histone H2A gene relies on cis regulative sequences located in the 5′ and 3′ regions and including the enhancer blocker sns J. Mol. Biol. 342 2004 1367 1377
24. P. Di Simone, A. Di Leonardo, G. Costanzo, R. Melfi, and G. Spinelli The sea urchin sns insulator blocks CMV enhancer following integration in human cells Biochem. Biophys. Res. Commun. 284 2001 987 992
25. S. Acuto, M. Donovan-Peluso, N. Giambona, and A. Bank The role of human globin gene promoters in the expression of hybrid genes in erythroid and non-erythroid cells Biochem. Biophys. Res. Commun. 143 1987 1099 1106
26. J.H. Chung, M. Whiteley, and G. Felsenfeld A 5′ element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila Cell 74 1993 505 514
27. M. Vitale, R. Calzolari, R. Di Marzo, S. Acuto, and A. Maggio A region upstream of the human delta-globin gene shows a stage-specific interaction with globin promoters in erythroid cell lines Blood Cells, Mol. Dis. 27 2001 874 881
28. A.C. Bell, A.G. West, and G. Felsenfeld The protein CTCF is required for the enhancer blocking activity of vertebrate insulators Cell 98 1999 387 396
29. F. Recillas-Targa, A.C. Bell, and G. Felsenfeld Positional enhancer-blocking activity of the chicken beta-globin insulator in transiently transfected cells Proc. Natl. Acad. Sci. U. S. A. 96 1999 14354 14359
30. N.B. Sutter, D. Scalzo, S. Fiering, M. Groudine, and D.I. Martin Chromatin insulation by a transcriptional activator Proc. Natl. Acad. Sci. U. S. A. 100 2003 1105 1110
31. G. Fourel, F. Magdinier, and E. Gilson Insulator dynamics and the setting of chromatin domains Bioessays 26 2004 523 532
32. C.E. Thomas, A. Ehrhardt, and M.A. Kay Progress and problems with the use of viral vectors for gene therapy Nat. Rev., Genet. 4 2003 346 358
33. S. Hacein-Bey-Abina, C. von Kalle, M. Schmidt, F. Le Deist, N. Wulffraat, E. McIntyre, I. Radford, J.L. Villeval, C.C. Fraser, M. Cavazzana-Calvo, and A. Fischer A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency N. Engl. J. Med. 348 2003 255 256