Attempts to characterize the NBD heterodimer of MRP1: Transient complex formation involves Gly771 of the ABC signature sequence but does not enhance the intrinsic ATPase activity

Biochemical Journal

Volumn 391, Issue 3, 2005, Pages 481-490

  Ramaen, Odile ^a   Sizun, Christina ^a   Pamlard, Olivier ^a   Jacquet, Eric ^a   Lallemand, Jean Yves ^a  

^a CNRS   (France)

Author keywords

ABC signature; ABC transporter; ABCC1; Biochemical and NMR studies; MRP1; Nucleotide binding domain (NBD)

Indexed keywords

ACTIVATION ENERGY; CELLS; CHEMOTHERAPY; COMPLEXATION; GEL PERMEATION CHROMATOGRAPHY; MONOMERS; PROTEINS;

ABC SIGNATURE; ABC TRANSPORTER; ABCC1; BIOCHEMICAL AND NMR STUDIES; MRP1; NUCLEOTIDE-BINDING DOMAIN;

ADENOSINETRIPHOSPHATE;

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; MONOMER; MULTIDRUG RESISTANCE PROTEIN 1; NUCLEOTIDE BINDING PROTEIN; SERINE; VALINE;

ARTICLE; COMPLEX FORMATION; ENZYME ACTIVITY; GEL FILTRATION CHROMATOGRAPHY; GENE SEQUENCE; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ADENOSINE TRIPHOSPHATASES; AMINO ACID SEQUENCE; DIMERIZATION; GENE EXPRESSION REGULATION; GLYCINE; HL-60 CELLS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS;

EID: 27744498371     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20050897     Document Type: Article

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