Analogues of thiolactomycin: Potential drugs with enhanced anti-mycobacterial activity

Microbiology

Volumn 148, Issue 10, 2002, Pages 3101-3109

  Douglas, James D ^a   Senior, Suzanne J ^a   Morehouse, Caroline ^a   Phetsukiri, Benjawan ^a   Campbell, Ian B ^a   Besra, Gurdyal S ^a   Minnikin, David E ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Antibiotics; Mycobacteria; Mycolic acids; Tuberculosis

Indexed keywords

3 [3,7 BISMETHYL OCTA 2,6 BISENYL] 3,5 BISMETHYL THIOPHENE 2,4 DIONE; 3,3,5 TRISMETHYL THIOPHENE 2,4 DIONE; 4 HYDROXY 3,5 BISMETHYL 5 (3 METHYL BUTYL) 5H THIOPHENE 2 ONE; 4 HYDROXY 3,5 BISMETHYL 5 OCTYL 5H THIOPHENE 2 ONE; 5 [(E) 3,7 BISMETHYL OCTA 2,6 BISENYL] 4 HYDROXY 3,5 BISMETHYL 5H THIOPHENE 2 ONE; ALKYL GROUP; ANION; BASE; CELL EXTRACT; FATTY ACID SYNTHASE; HALIDE; ISOPRENOID; MYCOLIC ACID; ORGANOLITHIUM COMPOUND; TERPENOID DERIVATIVE; TETRAHYDROFURAN; THIOLACTOMYCIN; THIOLACTONE; TRIMETHYLSILYL DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; FATTY ACID SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ACTINOBACTERIA (CLASS); CORYNEBACTERINEAE; MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; UNCULTURED ACTINOMYCETE;

EID: 0036775387     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-148-10-3101     Document Type: Article

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