Mutations in the thyrotropin receptor signal transduction pathway in the hyperfunctioning thyroid nodules from multinodular goiters: A study in the turkish population

Endocrine Journal

Volumn 52, Issue 5, 2005, Pages 577-585

  Gozu, Hulya ^a,c   Avsar, Melike ^b   Bircan, Rifat ^b   Sahin, Serap ^b   Deyneli, Oguzhan ^a   Cirakoglu, Beyazit ^b   Akalin, Sema ^a  

^a MARMARA UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^b MARMARA UNIVERSITY   (Turkey)

^c NONE   (Turkey)

Author keywords

Gs gene; Mutations; Protein kinase A gene; Thyroid nodules; Thyrotropin receptor

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; GENOMIC DNA; PROTEIN SUBUNIT; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; THYROTROPIN RECEPTOR;

ADULT; AGED; ALPHA CHAIN; ARTICLE; CLINICAL ARTICLE; DNA EXTRACTION; DNA SEQUENCE; ENZYME ACTIVE SITE; EXON; FEMALE; GENE FREQUENCY; GENE IDENTIFICATION; GENE LOCATION; GENE MUTATION; GENETIC ANALYSIS; GENETIC SCREENING; GOITER; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; MALE; MULTINODULAR GOITER; NODULAR GOITER; SIGNAL TRANSDUCTION; SINGLE STRAND CONFORMATION POLYMORPHISM; SOMATIC MUTATION; THYROID NODULE; THYROIDECTOMY; TURKEY (REPUBLIC);

ADOLESCENT; ADULT; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FEMALE; GOITER, NODULAR; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; MALE; MIDDLE AGED; POINT MUTATION; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RECEPTORS, THYROTROPIN; SIGNAL TRANSDUCTION; TURKEY;

EID: 27744477803     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.52.577     Document Type: Article

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