Theoretical studies of Alzheimer's disease drug candidate 3-[(2,4-dimethoxy)benzylidene]-anabaseine (GTS-21) and its derivatives

Biochemical and Biophysical Research Communications

Volumn 338, Issue 2, 2005, Pages 1059-1064

  Wei, Dong Qing ^a,b,e   Sirois, Suzane ^c,e   Du, Qi Shi ^a,e   Arias, Hugo R ^d   Chou, Kuo Chen ^a,e  

^a TIANJIN NORMAL UNIVERSITY   (China)

^b Gina Cody School of Engineering and Computer Science   (Canada)

^c UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^d WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

^e GORDON LIFE SCIENCE INSTITUTE   (United States)

Author keywords

7 Nicotinic acetylcholine receptor; Alzheimer's Disease; Docking; GTS 21; Molecular modeling; Structural bioinformatics

Indexed keywords

3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; ANABASINE DERIVATIVE; CHOLINERGIC RECEPTOR;

ALZHEIMER DISEASE; ARTICLE; DRUG BINDING SITE; DRUG DESIGN; DRUG RECEPTOR BINDING; ENERGY; METABOLITE; MOLECULAR MODEL; PRIORITY JOURNAL; THEORETICAL MODEL;

ALZHEIMER DISEASE; BENZYLIDENE COMPOUNDS; BINDING SITES; BRAIN CHEMISTRY; COMPUTER SIMULATION; DIMERIZATION; DRUG DELIVERY SYSTEMS; DRUG DESIGN; HUMANS; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; PYRIDINES; RECEPTORS, NICOTINIC; SEQUENCE ANALYSIS, PROTEIN;

EID: 27744476837     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.10.047     Document Type: Article

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