-
1
-
-
0034837386
-
A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster
-
Reiter, L., Potocki, L., Chien, S., Gribskov, M., and Bier, E. 2001. A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Res. 11:1114-1125.
-
(2001)
Genome Res.
, vol.11
, pp. 1114-1125
-
-
Reiter, L.1
Potocki, L.2
Chien, S.3
Gribskov, M.4
Bier, E.5
-
2
-
-
14344263852
-
Emerging technologies for gene manipulation in Drosophila melanogaster
-
Venken, K.J., and Bellen, H.J. 2005. Emerging technologies for gene manipulation in Drosophila melanogaster. Nat. Rev. Genet. 6:167-178.
-
(2005)
Nat. Rev. Genet.
, vol.6
, pp. 167-178
-
-
Venken, K.J.1
Bellen, H.J.2
-
3
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand, A.H., and Perrimon, N. 1993. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development. 118:401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
4
-
-
2542468586
-
Can flies help humans treat neurodegenerative diseases?
-
Marsh, J.L., and Thompson, L.M. 2004. Can flies help humans treat neurodegenerative diseases? Bioessays. 26:485-496.
-
(2004)
Bioessays
, vol.26
, pp. 485-496
-
-
Marsh, J.L.1
Thompson, L.M.2
-
5
-
-
8844247123
-
The genetics of Drosophila transgenics
-
Roman, G. 2004. The genetics of Drosophila transgenics. Bioessays. 26:1243-1253.
-
(2004)
Bioessays
, vol.26
, pp. 1243-1253
-
-
Roman, G.1
-
6
-
-
27644498533
-
Disease-related phenotypes in a Drosophila model of hereditary spastic paraplegia are ameliorated by treatment with vinblastine
-
doi:10.1172/JCI24694
-
Orso, G., et al. 2005. Disease-related phenotypes in a Drosophila model of hereditary spastic paraplegia are ameliorated by treatment with vinblastine. J. Clin. Invest. 115:3026-3034. doi:10.1172/JCI24694.
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 3026-3034
-
-
Orso, G.1
-
7
-
-
0037328987
-
Science in motion: Common molecular pathological themes emerge in the hereditary spastic paraplegias
-
Reid, E. 2003. Science in motion: common molecular pathological themes emerge in the hereditary spastic paraplegias. J. Med. Genet. 40:81-86.
-
(2003)
J. Med. Genet.
, vol.40
, pp. 81-86
-
-
Reid, E.1
-
8
-
-
2942531080
-
Hereditary spastic paraplegia: Spastin phenotype and function
-
Fink, J.K., and Rainier, S. 2004. Hereditary spastic paraplegia: spastin phenotype and function. Arch. Neurol. 61:830-833.
-
(2004)
Arch. Neurol.
, vol.61
, pp. 830-833
-
-
Fink, J.K.1
Rainier, S.2
-
9
-
-
17144424690
-
The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules
-
Roll-Mecak, A., and Vale, R.D. 2005. The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules. Curr. Biol. 15:650-655.
-
(2005)
Curr. Biol.
, vol.15
, pp. 650-655
-
-
Roll-Mecak, A.1
Vale, R.D.2
-
10
-
-
13944283245
-
Linking axonal degeneration to microtubule remodeling by Spastin-mediated microtubule severing
-
Evans, K.J., Gomes, E.R., Reisenweber, S.M., Gundersen, G.G., and Lauring, B.P. 2005. Linking axonal degeneration to microtubule remodeling by Spastin-mediated microtubule severing. J. Cell Biol. 168:599-606.
-
(2005)
J. Cell Biol.
, vol.168
, pp. 599-606
-
-
Evans, K.J.1
Gomes, E.R.2
Reisenweber, S.M.3
Gundersen, G.G.4
Lauring, B.P.5
-
11
-
-
3142647116
-
The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function
-
Trotta, N., Orso, G., Rossetto, M.G., Daga, A., and Broadie, K. 2004. The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function. Curr. Biol. 14:1135-1147.
-
(2004)
Curr. Biol.
, vol.14
, pp. 1135-1147
-
-
Trotta, N.1
Orso, G.2
Rossetto, M.G.3
Daga, A.4
Broadie, K.5
-
12
-
-
13944280702
-
Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function
-
Sherwood, N.T., Sun, Q., Xue, M., Zhang, B., and Zinn, K. 2004. Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function. PLoS Biol. 2:e429.
-
(2004)
PLoS Biol.
, vol.2
-
-
Sherwood, N.T.1
Sun, Q.2
Xue, M.3
Zhang, B.4
Zinn, K.5
-
13
-
-
23444460879
-
Morphogens and synaptogenesis in Drosophila
-
Marques, G. 2005. Morphogens and synaptogenesis in Drosophila. J. Neurobiol. 64:417-434.
-
(2005)
J. Neurobiol.
, vol.64
, pp. 417-434
-
-
Marques, G.1
-
14
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
Jackson, A.L., et al. 2003. Expression profiling reveals off-target gene regulation by RNAi. Nat. Biotechnol. 21:635-637.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 635-637
-
-
Jackson, A.L.1
-
15
-
-
0042972933
-
Activation of the interferon system by short-interfering RNAs
-
Sledz, C.A., Holko, M., de Veer, M.J., Silverman, R.H., and Williams, B.R. 2003. Activation of the interferon system by short-interfering RNAs. Nat. Cell Biol. 5:834-839.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 834-839
-
-
Sledz, C.A.1
Holko, M.2
De Veer, M.J.3
Silverman, R.H.4
Williams, B.R.5
-
16
-
-
0035958642
-
Tauopathy in Drosophila: Neurodegeneration without neurofibrillary tangles
-
Wittmann, C.W., et al. 2001. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science. 293:711-714.
-
(2001)
Science
, vol.293
, pp. 711-714
-
-
Wittmann, C.W.1
-
17
-
-
0021187118
-
Neurological complications of antineoplastic therapy
-
Shapiro, W.R., and Young, D.F. 1984. Neurological complications of antineoplastic therapy. Acta Neurol. Scand. Suppl. 100:125-132.
-
(1984)
Acta Neurol. Scand. Suppl.
, vol.100
, pp. 125-132
-
-
Shapiro, W.R.1
Young, D.F.2
-
18
-
-
0042035602
-
Human neurodegenerative disease modeling using Drosophila
-
Bonini, N.M., and Fortini, M.E. 2003. Human neurodegenerative disease modeling using Drosophila. Annu. Rev. Neurosci. 26:627-656.
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 627-656
-
-
Bonini, N.M.1
Fortini, M.E.2
-
19
-
-
0033581027
-
Preventing neurodegeneration in the Drosophila mutant bubblegum
-
Min, K.T., and Benzer, S. 1999. Preventing neurodegeneration in the Drosophila mutant bubblegum. Science. 284:1985-1988.
-
(1999)
Science
, vol.284
, pp. 1985-1988
-
-
Min, K.T.1
Benzer, S.2
-
20
-
-
0033588991
-
Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melanogaster
-
Ye, Y., and Fortini, M.E. 1999. Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melanogaster. J. Cell Biol. 146:1351-1364.
-
(1999)
J. Cell Biol.
, vol.146
, pp. 1351-1364
-
-
Ye, Y.1
Fortini, M.E.2
-
21
-
-
0038039295
-
Neuromuscular defects in a Drosophila survival motor neuron gene mutant
-
Chan, Y.B., et al. 2003. Neuromuscular defects in a Drosophila survival motor neuron gene mutant. Hum. Mol. Genet. 12:1367-1376.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1367-1376
-
-
Chan, Y.B.1
-
22
-
-
18544392423
-
Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila
-
Warrick, J.M, et al. 1998. Expanded polyglutamine protein forms nuclear inclusions and causes neural degeneration in Drosophila. Cell. 93:939-949.
-
(1998)
Cell
, vol.93
, pp. 939-949
-
-
Warrick, J.M.1
-
23
-
-
0032168160
-
Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons
-
Jackson, G.R., et al. 1998. Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. Neuron. 21:633-642.
-
(1998)
Neuron
, vol.21
, pp. 633-642
-
-
Jackson, G.R.1
-
24
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany, M.B., and Bender, W.W. 2000. A Drosophila model of Parkinson's disease. Nature. 404:394-398.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
25
-
-
0032506013
-
Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype
-
Fossgreen, A., et al. 1998. Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype. Proc. Natl. Acad. Sci. U. S. A. 95:13703-13708.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 13703-13708
-
-
Fossgreen, A.1
|