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Volumn 50, Issue 6, 1996, Pages 1511-1519

Transgenic mice with high levels of superoxide dismutase activity are protected from the neurotoxic effects of 2′-NH2-MPTP on serotonergic and noradrenergic nerve terminals

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; BRAIN ENZYME; COPPER ZINC SUPEROXIDE DISMUTASE; NEUROTOXIN; SEROTONIN; SEROTONIN RECEPTOR;

EID: 0030463422     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (42)

References (55)
  • 2
    • 0020680904 scopus 로고
    • Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
    • Langston, J. W., P. Ballard, J. W. Tetrud, and I. Irwin. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science (Washington D. C.) 219:979-980 (1983).
    • (1983) Science (Washington D. C.) , vol.219 , pp. 979-980
    • Langston, J.W.1    Ballard, P.2    Tetrud, J.W.3    Irwin, I.4
  • 3
    • 0026089919 scopus 로고
    • Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: An in vivo autoradiographic study
    • Herkenham, M., M. D. Little, K. Bankiewicz, S. C. Yang, S. P. Markey, and J. N. Johannessen. Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study. Neuroscience 40:133-158 (1991).
    • (1991) Neuroscience , vol.40 , pp. 133-158
    • Herkenham, M.1    Little, M.D.2    Bankiewicz, K.3    Yang, S.C.4    Markey, S.P.5    Johannessen, J.N.6
  • 4
    • 0001496694 scopus 로고
    • A primate model of Parkinsonism: Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Burns, R. S., C. C. Chiueh, S. P. Markey, M. H. Ebert, D. M. Jacobowitz, and I. J. Kopin. A primate model of Parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc. Natl. Acad. Sci. USA 80:4546-4550 (1983).
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4546-4550
    • Burns, R.S.1    Chiueh, C.C.2    Markey, S.P.3    Ebert, M.H.4    Jacobowitz, D.M.5    Kopin, I.J.6
  • 5
    • 0021280826 scopus 로고
    • Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice
    • Heikkila, R. E., A. Hess, and R. C. Duvoisin. Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice. Science (Washington D. C.) 224:1451-1453 (1984).
    • (1984) Science (Washington D. C.) , vol.224 , pp. 1451-1453
    • Heikkila, R.E.1    Hess, A.2    Duvoisin, R.C.3
  • 6
    • 0021843225 scopus 로고
    • Pharmacological interference with the neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in the mouse
    • Sundstrom, E., and G. Jonsson. Pharmacological interference with the neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in the mouse. Eur. J. Pharmacol 110: 293-299 (1985).
    • (1985) Eur. J. Pharmacol , vol.110 , pp. 293-299
    • Sundstrom, E.1    Jonsson, G.2
  • 7
    • 0024516540 scopus 로고
    • Studies on semirigid tricyclic analogues of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Booth, R. G., A. Trevor, T. P. Singer, and N. J. Castagnoli. Studies on semirigid tricyclic analogues of the nigrostriatal toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J. Med. Chem. 32:473-477 (1989).
    • (1989) J. Med. Chem. , vol.32 , pp. 473-477
    • Booth, R.G.1    Trevor, A.2    Singer, T.P.3    Castagnoli, N.J.4
  • 8
    • 0022382281 scopus 로고
    • The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety
    • Bradbury, A. J., B. Costall, A. M. Domeney, B. Testa, P. G. Jenner, C. D. Marsden, and R. J. Naylor. The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety. Neurosci. Lett. 61:121-126 (1985).
    • (1985) Neurosci. Lett. , vol.61 , pp. 121-126
    • Bradbury, A.J.1    Costall, B.2    Domeney, A.M.3    Testa, B.4    Jenner, P.G.5    Marsden, C.D.6    Naylor, R.J.7
  • 9
    • 0023618442 scopus 로고
    • 1,2,3,6-tetrahydro-1-methyl-4-(methylpyrrol-2-yl)pyridine: Studies on the mechanism of action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Finnegau, K. T., I. Irwin, L. E. Delanney, G. A. Ricaurte, and J. W. Langsten. 1,2,3,6-tetrahydro-1-methyl-4-(methylpyrrol-2-yl)pyridine: studies on the mechanism of action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J. Pharmacol. Exp. Ther. 242:1144-1151 (1987).
    • (1987) J. Pharmacol. Exp. Ther. , vol.242 , pp. 1144-1151
    • Finnegau, K.T.1    Irwin, I.2    Delanney, L.E.3    Ricaurte, G.A.4    Langsten, J.W.5
  • 10
    • 0022340694 scopus 로고
    • Comparison of 1-methyl-4-(p-chlorophenyl)-1,2,3,6-tetrahydropyridine, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and p-chloroamphetamine as monoamine depletors
    • Fuller, R. W., L. S. Hemrick, and D. W. Robertson. Comparison of 1-methyl-4-(p-chlorophenyl)-1,2,3,6-tetrahydropyridine, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and p-chloroamphetamine as monoamine depletors. Res. Commun. Chem. Pathol. Pharmacol. 50:57-65 (1985).
    • (1985) Res. Commun. Chem. Pathol. Pharmacol. , vol.50 , pp. 57-65
    • Fuller, R.W.1    Hemrick, L.S.2    Robertson, D.W.3
  • 11
    • 0027381503 scopus 로고
    • Development of fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs with potent nigrostriatal toxicity for potential use in positron emission tomography studies
    • Harik, S. I., N. J. Riachi, M. A. Hritz, M. S. Berridge, and L. M. Sayre. Development of fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs with potent nigrostriatal toxicity for potential use in positron emission tomography studies. J. Pharmacol. Exp. Ther. 266:790-795 (1993).
    • (1993) J. Pharmacol. Exp. Ther. , vol.266 , pp. 790-795
    • Harik, S.I.1    Riachi, N.J.2    Hritz, M.A.3    Berridge, M.S.4    Sayre, L.M.5
  • 12
    • 0026584944 scopus 로고
    • Persistent depletion of striatal dopamine and cortical norepinephrine in mice by 1-methyl-4-phenyl-1,2,3,6-tetrahydro-3-pyridinol (MPTP-3-OL), an analog of MPTP
    • Hemrick, L. S., D. W. Robertson, J. J. Krushinski, and R. W. Fuller. Persistent depletion of striatal dopamine and cortical norepinephrine in mice by 1-methyl-4-phenyl-1,2,3,6-tetrahydro-3-pyridinol (MPTP-3-OL), an analog of MPTP. Life Sci. 50:573-582 (1992).
    • (1992) Life Sci. , vol.50 , pp. 573-582
    • Hemrick, L.S.1    Robertson, D.W.2    Krushinski, J.J.3    Fuller, R.W.4
  • 13
    • 0025198542 scopus 로고
    • Studies on 4-benzyl-1-methyl-1,2,3,6-tetrahydropyridine, a nonneurotoxic analogue of the Parkineonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Naiman, N., H. Rollema, E. Johnson, and N. J. Castagnoli. Studies on 4-benzyl-1-methyl-1,2,3,6-tetrahydropyridine, a nonneurotoxic analogue of the Parkineonian inducing agent 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Chem. Res. Toxicol. 3:133-138 (1990).
    • (1990) Chem. Res. Toxicol. , vol.3 , pp. 133-138
    • Naiman, N.1    Rollema, H.2    Johnson, E.3    Castagnoli, N.J.4
  • 14
    • 0025735358 scopus 로고
    • Investigation of the possible dopaminergic toxicity of 1-methyl-3-phenyl-1,2,3,6-tetrahydropyridine, an isomer to the neurotoxin MPTP
    • Nilsson, K., A. Hallberg, E. Pileblad, and A. Tunek. Investigation of the possible dopaminergic toxicity of 1-methyl-3-phenyl-1,2,3,6-tetrahydropyridine, an isomer to the neurotoxin MPTP. Pharmacol. Toxicol. 69:38-42 (1991).
    • (1991) Pharmacol. Toxicol. , vol.69 , pp. 38-42
    • Nilsson, K.1    Hallberg, A.2    Pileblad, E.3    Tunek, A.4
  • 15
    • 0023934196 scopus 로고
    • Potent neurotoxic fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs as potential probes in models of Parkinson disease
    • Riachi, N. J., P. K. Arora, L. M. Sayre, and S. I. Harik. Potent neurotoxic fluorinated 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine analogs as potential probes in models of Parkinson disease. J. Neurochem. 50:1319-1321 (1988).
    • (1988) J. Neurochem. , vol.50 , pp. 1319-1321
    • Riachi, N.J.1    Arora, P.K.2    Sayre, L.M.3    Harik, S.I.4
  • 16
    • 0023695241 scopus 로고
    • In vivo dopaminergic neurotoxicity of the 2-beta-methylcarbolinium ion, a potential endogenous MPP+ analog
    • Rollema, H., R. G. Booth, and N. J. Castagnoli. In vivo dopaminergic neurotoxicity of the 2-beta-methylcarbolinium ion, a potential endogenous MPP+ analog. Eur. J. Pharmacol. 153:131-134 (1988).
    • (1988) Eur. J. Pharmacol. , vol.153 , pp. 131-134
    • Rollema, H.1    Booth, R.G.2    Castagnoli, N.J.3
  • 17
    • 0024321011 scopus 로고
    • Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. I. Evaluation of the biological activity of MPTP analogs
    • Youngster, S. K., P. K. Sonealla, B. A. Sieber, and R. E. Heikkila. Structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced neurotoxicity. I. Evaluation of the biological activity of MPTP analogs. J. Pharmacol. Exp. Ther. 249:820-828 (1989).
    • (1989) J. Pharmacol. Exp. Ther. , vol.249 , pp. 820-828
    • Youngster, S.K.1    Sonealla, P.K.2    Sieber, B.A.3    Heikkila, R.E.4
  • 18
    • 0023093744 scopus 로고
    • The development of amine substituted analogues of MPTP as unique tools for the study of MPTP toxicity and Parkinson's disease
    • Johannessen, J. N., J. M. Savitt, C. J. Markey, J. P. Bacon, A. Weisz, D. S. Hanselman, and S. P. Markey. The development of amine substituted analogues of MPTP as unique tools for the study of MPTP toxicity and Parkinson's disease. Life Sci. 40:697-704 (1987).
    • (1987) Life Sci. , vol.40 , pp. 697-704
    • Johannessen, J.N.1    Savitt, J.M.2    Markey, C.J.3    Bacon, J.P.4    Weisz, A.5    Hanselman, D.S.6    Markey, S.P.7
  • 20
    • 0027511558 scopus 로고
    • 2-MPTP): A comparative study with 2′-CHS-MPTP and MPTP
    • 2-MPTP): a comparative study with 2′-CHS-MPTP and MPTP. J. Neurochem. 60: 1167-1170 (1993).
    • (1993) J. Neurochem. , vol.60 , pp. 1167-1170
    • Andrews, A.M.1    Murphy, D.L.2
  • 21
    • 0027786911 scopus 로고
    • 2-MPTP in Swiss Webster mice: Evidence for long term (six month) depletions in cortical and hippocampal 5-HT and NE, differential protection by selective uptake inhibitors or clorgyline, and functional changes in central 5-HT neurotransmission
    • 2-MPTP in Swiss Webster mice: evidence for long term (six month) depletions in cortical and hippocampal 5-HT and NE, differential protection by selective uptake inhibitors or clorgyline, and functional changes in central 5-HT neurotransmission. J. Pharmacol. Exp. Ther. 267:1432-1439 (1993).
    • (1993) J. Pharmacol. Exp. Ther. , vol.267 , pp. 1432-1439
    • Andrews, A.M.1    Murphy, D.L.2
  • 22
    • 0027504812 scopus 로고
    • 2-MPTP-induced depletions in serotonin and norepinephrine
    • 2-MPTP-induced depletions in serotonin and norepinephrine. Eur. J. Pharmacol. 250:215-221 (1993).
    • (1993) Eur. J. Pharmacol. , vol.250 , pp. 215-221
    • Andrews, A.M.1    Murphy, D.L.2
  • 23
    • 0021224694 scopus 로고
    • Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors
    • Heikkila, R. E., L. Manzino, F. S. Cabbat, and R. C. Duvoisin. Protection against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine by monoamine oxidase inhibitors. Nature (Lond.) 311: 467-469 (1984).
    • (1984) Nature (Lond.) , vol.311 , pp. 467-469
    • Heikkila, R.E.1    Manzino, L.2    Cabbat, F.S.3    Duvoisin, R.C.4
  • 24
    • 0021137683 scopus 로고
    • Intraneuronal generation of a pyridinium metabolite may cause drug-induced Parkinsonism
    • Markey, S. P., J. N. Johannessen, C. C. Chiueh, R. S. Burns, and M. A. Herkenham. Intraneuronal generation of a pyridinium metabolite may cause drug-induced Parkinsonism. Nature (Lond.) 311:464-467 (1984).
    • (1984) Nature (Lond.) , vol.311 , pp. 464-467
    • Markey, S.P.1    Johannessen, J.N.2    Chiueh, C.C.3    Burns, R.S.4    Herkenham, M.A.5
  • 25
    • 0000340348 scopus 로고
    • Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity
    • Javitch, J. A., R. J. D'Amato, S. M. Strittmatter, and S. H. Snyder. Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. Proc. Natl. Acad. Sci. USA 82:2173-2177 (1985).
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 2173-2177
    • Javitch, J.A.1    D'Amato, R.J.2    Strittmatter, S.M.3    Snyder, S.H.4
  • 26
    • 0026698273 scopus 로고
    • Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: Effects of MPP+
    • Chiueh, C. C., G. Krishna, P. Tulsi, T. Obata, K. Lang, S. J. Huang, and D. L. Murphy. Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: effects of MPP+. Free Radical Biol. Med. 13:581-583 (1992).
    • (1992) Free Radical Biol. Med. , vol.13 , pp. 581-583
    • Chiueh, C.C.1    Krishna, G.2    Tulsi, P.3    Obata, T.4    Lang, K.5    Huang, S.J.6    Murphy, D.L.7
  • 27
    • 0026598930 scopus 로고
    • Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: Evidence for free radical involvement
    • Cleeter, M. W., J. M. Cooper, and A. H. Schapira. Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement. J. Neurochem. 58:786-789 (1992).
    • (1992) J. Neurochem. , vol.58 , pp. 786-789
    • Cleeter, M.W.1    Cooper, J.M.2    Schapira, A.H.3
  • 28
    • 0027941334 scopus 로고
    • MPTP-induced oxidative stress and neurotoxicity are age-dependent: Evidence from measures of reactive oxygen species and striatal dopamine levels
    • Ali, S. F., S. N. David, G. D. Newport, J. L. Cadet, and W. Slikker, Jr. MPTP-induced oxidative stress and neurotoxicity are age-dependent: evidence from measures of reactive oxygen species and striatal dopamine levels. Synapse (N. Y.) 18:27-34 (1994).
    • (1994) Synapse (N. Y.) , vol.18 , pp. 27-34
    • Ali, S.F.1    David, S.N.2    Newport, G.D.3    Cadet, J.L.4    Slikker Jr., W.5
  • 29
    • 0026583465 scopus 로고
    • Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
    • Przedborski, S., V. Kostic, L. V. Jackson, A. B. Naini, S. Simonetti, S. Fahn, E. Carlson, C. J. Epstein, and J. L. Cadet. Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. J. Neurosci. 12:1658-1667 (1992).
    • (1992) J. Neurosci. , vol.12 , pp. 1658-1667
    • Przedborski, S.1    Kostic, V.2    Jackson, L.V.3    Naini, A.B.4    Simonetti, S.5    Fahn, S.6    Carlson, E.7    Epstein, C.J.8    Cadet, J.L.9
  • 31
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell, B. Reactive oxygen species and the central nervous system. J. Neurochem. 59:1609-1623 (1992).
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 32
    • 0027972286 scopus 로고
    • Attenuation of methamphetamine-induced neurotoxicity in copper/zinc Superoxide dismutase transgenic mice
    • Cadet, J. L., P. Sheng, S. Ali, R. Rothman, E. Carlson, and C. Epstein. Attenuation of methamphetamine-induced neurotoxicity in copper/zinc Superoxide dismutase transgenic mice. J. Neurochem. 62:380-383 (1994).
    • (1994) J. Neurochem. , vol.62 , pp. 380-383
    • Cadet, J.L.1    Sheng, P.2    Ali, S.3    Rothman, R.4    Carlson, E.5    Epstein, C.6
  • 33
    • 0029126705 scopus 로고
    • Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): Evidence from using CuZn-superoxide dismutase transgenic mice
    • Cadet, J. L., B. Ladenheim, H. Hirata, R. B. Rothman, S. A. Ali, E. Carlson, C. Epstein, and T. H. Moran. Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): evidence from using CuZn-superoxide dismutase transgenic mice. Synapse (N. Y.) 21:169-176 (1995).
    • (1995) Synapse (N. Y.) , vol.21 , pp. 169-176
    • Cadet, J.L.1    Ladenheim, B.2    Hirata, H.3    Rothman, R.B.4    Ali, S.A.5    Carlson, E.6    Epstein, C.7    Moran, T.H.8
  • 37
    • 0023638820 scopus 로고
    • Characteristics of 1-methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the mouse
    • Sonsalla, P. K., S. K. Youngster, M. V. Kindt, and R. E. Heikkila. Characteristics of 1-methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine-induced neurotoxicity in the mouse. J. Pharmacol. Exp. Ther. 242:850-857 (1987).
    • (1987) J. Pharmacol. Exp. Ther. , vol.242 , pp. 850-857
    • Sonsalla, P.K.1    Youngster, S.K.2    Kindt, M.V.3    Heikkila, R.E.4
  • 38
    • 0001472422 scopus 로고
    • Criteria for assessing drug-induced biochemical alterations and degeneration of serotonergic neurons
    • R. Paoletti, P. M. Vanhoutte, N. Brunello, and F. M. Maggi, eds.. Kluwer Academic, Dordrecht, The Netherlands
    • Battaglia, G. Criteria for assessing drug-induced biochemical alterations and degeneration of serotonergic neurons, in Serotonin: From Cell Biology to Pharmacology and Therapeutics (R. Paoletti, P. M. Vanhoutte, N. Brunello, and F. M. Maggi, eds.). Kluwer Academic, Dordrecht, The Netherlands, 651-660 (1990).
    • (1990) Serotonin: from Cell Biology to Pharmacology and Therapeutics , pp. 651-660
    • Battaglia, G.1
  • 39
    • 0028986577 scopus 로고
    • Methamphetamine-induced serotonin neurotoxicity is mediated by superoxide radicals
    • Hirata, H., B. Ladenheim, R. B. Rothman, C. Epstein, and J. L. Cadet. Methamphetamine-induced serotonin neurotoxicity is mediated by superoxide radicals. Brain Res. 677:345-347 (1995).
    • (1995) Brain Res. , vol.677 , pp. 345-347
    • Hirata, H.1    Ladenheim, B.2    Rothman, R.B.3    Epstein, C.4    Cadet, J.L.5
  • 40
    • 0028064964 scopus 로고
    • Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: Evidence for a primary involvement of energy depletion
    • Bates, T. E., S. J. R. Heales, S. E. C. Davies, P. Boakye, and J. B. Clark. Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. J. Neurochem. 63:640-648 (1994).
    • (1994) J. Neurochem. , vol.63 , pp. 640-648
    • Bates, T.E.1    Heales, S.J.R.2    Davies, S.E.C.3    Boakye, P.4    Clark, J.B.5
  • 41
    • 0027159159 scopus 로고
    • Methamphetamine-induced dopamine overflow and injury to striatal dopamine terminals: Attenuation by dopamine D1 or D2 antagonists
    • O'Dell, S. J., F. B. Weihmuller, and J. F. Marshall. Methamphetamine-induced dopamine overflow and injury to striatal dopamine terminals: attenuation by dopamine D1 or D2 antagonists. J. Neurochem. 60:1792-1799 (1993).
    • (1993) J. Neurochem. , vol.60 , pp. 1792-1799
    • O'Dell, S.J.1    Weihmuller, F.B.2    Marshall, J.F.3
  • 42
    • 0027411564 scopus 로고
    • Striatal dopamine release in vivo following neurotoxic doses of methamphetamine and effect of the neuroprotective drugs, chlormethiazole and dizocilpine
    • Baldwin, H. A., M. I. Colado, T. K. Murray, R. J. De Souza, and A. R. Green. Striatal dopamine release in vivo following neurotoxic doses of methamphetamine and effect of the neuroprotective drugs, chlormethiazole and dizocilpine. Br. J. Pharmacol. 108:590-596 (1993).
    • (1993) Br. J. Pharmacol. , vol.108 , pp. 590-596
    • Baldwin, H.A.1    Colado, M.I.2    Murray, T.K.3    De Souza, R.J.4    Green, A.R.5
  • 43
    • 0027074081 scopus 로고
    • In vivo release of dopamine by perfusion of 1-methyl-4-phenylpyridinium ion in the striatum with a microdialysis technique
    • Obata, T., Y. Yamanaka, and C. C. Chiueh. In vivo release of dopamine by perfusion of 1-methyl-4-phenylpyridinium ion in the striatum with a microdialysis technique. Jpn. J. Pharmacol. 60:311-313 (1992).
    • (1992) Jpn. J. Pharmacol. , vol.60 , pp. 311-313
    • Obata, T.1    Yamanaka, Y.2    Chiueh, C.C.3
  • 44
    • 0028176861 scopus 로고
    • Blockade of striatal 5-hydroxytryptamine2 receptors reduces the increase in extracellular concentrations of dopamine produced by the amphetamine analogue 3,4-methylenedioxymethamphetamine
    • Schmidt, C. J., C. K. Sullivan, and G. M. Fadayel. Blockade of striatal 5-hydroxytryptamine2 receptors reduces the increase in extracellular concentrations of dopamine produced by the amphetamine analogue 3,4-methylenedioxymethamphetamine. J. Neurochem. 62:1382-1389 (1994).
    • (1994) J. Neurochem. , vol.62 , pp. 1382-1389
    • Schmidt, C.J.1    Sullivan, C.K.2    Fadayel, G.M.3
  • 45
    • 0022902786 scopus 로고
    • Oxidation of 5-hydroxytryptamine and 5,7-dihydroxytryptamine. A new oxidation pathway and formation of a novel neurotoxin
    • Wrona, M. Z., D. Lemordant, L. Lin, C. L. Blank, and G. Dryhurst. Oxidation of 5-hydroxytryptamine and 5,7-dihydroxytryptamine. A new oxidation pathway and formation of a novel neurotoxin. J. Med. Chem. 29:499-505 (1986).
    • (1986) J. Med. Chem. , vol.29 , pp. 499-505
    • Wrona, M.Z.1    Lemordant, D.2    Lin, L.3    Blank, C.L.4    Dryhurst, G.5
  • 46
    • 0018095085 scopus 로고
    • Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones
    • Graham, D. G. Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol. Pharmacol. 14:633-643 (1978).
    • (1978) Mol. Pharmacol. , vol.14 , pp. 633-643
    • Graham, D.G.1
  • 47
    • 0018148688 scopus 로고
    • Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro
    • Graham, D. G., S. M. Tiffany, W. R. Bell, Jr., and W. F. Gutknecht. Autoxidation versus covalent binding of quinones as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro. Mol. Pharmacol. 14:644-653 (1978).
    • (1978) Mol. Pharmacol. , vol.14 , pp. 644-653
    • Graham, D.G.1    Tiffany, S.M.2    Bell Jr., W.R.3    Gutknecht, W.F.4
  • 48
    • 0025141243 scopus 로고
    • Structure-neurotoxicity trends of analogues of 1-methyl-4-phenylpyridinium (MPP+), the cytotoxic metabolite of the dopaminergic neurotoxin MPTP
    • Arora, P. K., N. J. Riachi, G. C. Fiedler, M. P. Singh, F. Abdallah, S. I. Harik, and L. M. Sayre. Structure-neurotoxicity trends of analogues of 1-methyl-4-phenylpyridinium (MPP+), the cytotoxic metabolite of the dopaminergic neurotoxin MPTP. Life Sci. 46:379-390 (1990).
    • (1990) Life Sci. , vol.46 , pp. 379-390
    • Arora, P.K.1    Riachi, N.J.2    Fiedler, G.C.3    Singh, M.P.4    Abdallah, F.5    Harik, S.I.6    Sayre, L.M.7
  • 49
    • 0026754078 scopus 로고
    • Dopaminergic neurotoxicity of 1-methyl-4-phenylpyridinium analogs in cultured neurons: Relationship to the dopamine uptake system and inhibition of mitochondrial respiration
    • Saporito, M. S., R. E. Heikkila, S. K. Youngster, W. J. Nicklas, and H. M. Geller. Dopaminergic neurotoxicity of 1-methyl-4-phenylpyridinium analogs in cultured neurons: relationship to the dopamine uptake system and inhibition of mitochondrial respiration. J. Pharmacol. Exp. Ther. 260: 1400-1409 (1992).
    • (1992) J. Pharmacol. Exp. Ther. , vol.260 , pp. 1400-1409
    • Saporito, M.S.1    Heikkila, R.E.2    Youngster, S.K.3    Nicklas, W.J.4    Geller, H.M.5
  • 50
    • 0021810979 scopus 로고
    • Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
    • Nicklas, W. J., I. Vyas, and R. E. Heikkila. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Life Sci. 36:2503-2508 (1985).
    • (1985) Life Sci. , vol.36 , pp. 2503-2508
    • Nicklas, W.J.1    Vyas, I.2    Heikkila, R.E.3
  • 51
    • 0024997609 scopus 로고
    • 1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent Superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles
    • Hasegawa, E., K. Takeshige, T. Oishi, Y. Murai, and S. Minakami. 1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent Superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles. Biochem. Biophys. Res. Commun. 170:1049-1055 (1990).
    • (1990) Biochem. Biophys. Res. Commun. , vol.170 , pp. 1049-1055
    • Hasegawa, E.1    Takeshige, K.2    Oishi, T.3    Murai, Y.4    Minakami, S.5
  • 52
    • 0025285757 scopus 로고
    • alpha-Methyl-p-tyrosine pretreatment partially prevents methamphetamine-induced endogenous neurotoxin formation
    • Axt, K. J., D. L. Commins, G. Vosmer, and L. S. Seiden. alpha-Methyl-p-tyrosine pretreatment partially prevents methamphetamine-induced endogenous neurotoxin formation. Brain Res. 615:269-276 (1990).
    • (1990) Brain Res. , vol.615 , pp. 269-276
    • Axt, K.J.1    Commins, D.L.2    Vosmer, G.3    Seiden, L.S.4
  • 53
    • 0023617138 scopus 로고
    • Endogenously produced 5,6-dihydroxytryptamine may mediate the neurotoxic effects of para-chloroamphetamine
    • Commins, D. L., K. J. Axt, G. Vosmer, and L. S. Seiden. Endogenously produced 5,6-dihydroxytryptamine may mediate the neurotoxic effects of para-chloroamphetamine. Brain Res. 419:253-261 (1987).
    • (1987) Brain Res. , vol.419 , pp. 253-261
    • Commins, D.L.1    Axt, K.J.2    Vosmer, G.3    Seiden, L.S.4
  • 54
    • 0024366919 scopus 로고
    • Diminished serotonin uptake in platelets of transgenic mice with increased Cu/Zn-superoxide dismutase activity
    • Schickler, M., H. Knobler, K. B. Avraham, O. Elroy-Stein, and Y. Groner. Diminished serotonin uptake in platelets of transgenic mice with increased Cu/Zn-superoxide dismutase activity. Embo. J. 8:1385-1392 (1989).
    • (1989) Embo. J. , vol.8 , pp. 1385-1392
    • Schickler, M.1    Knobler, H.2    Avraham, K.B.3    Elroy-Stein, O.4    Groner, Y.5
  • 55
    • 0029115023 scopus 로고
    • Mice transgenic for copper/ zinc Superoxide dismutase exhibit increased markers of biogenic amine function
    • Schwartz, P. J., U. V. Berger, and J. T. Coyle. Mice transgenic for copper/ zinc Superoxide dismutase exhibit increased markers of biogenic amine function. J. Neurochem. 65:660-669 (1995).
    • (1995) J. Neurochem. , vol.65 , pp. 660-669
    • Schwartz, P.J.1    Berger, U.V.2    Coyle, J.T.3


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