-
1
-
-
0027214522
-
Trophic actions of transforming growth factor alpha on mesencephalic dopaminergic neurons developing in culture
-
Alexi, T. and Hefti, F. (1993) Trophic actions of transforming growth factor alpha on mesencephalic dopaminergic neurons developing in culture. Neuroscience, 55:903-918.
-
(1993)
Neuroscience
, vol.55
, pp. 903-918
-
-
Alexi, T.1
Hefti, F.2
-
2
-
-
0027171266
-
Oxidants, antioxidants, and the degenerative diseases of aging
-
Ames, B.N., Shigenaga, M.K., and Hagen, T.M. (1993) Oxidants, antioxidants, and the degenerative diseases of aging. Proc. Natl. Acad. Sci. USA 90:7915-7922.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7915-7922
-
-
Ames, B.N.1
Shigenaga, M.K.2
Hagen, T.M.3
-
3
-
-
0027389046
-
The nature of the trophic action of brain-derived neurotrophic factor, des(1-3)-insulin-like growth factor-1, and basic fibroblast growth factor on mesencephalic dopaminergic neurons developing in culture
-
Beck, K.D., Knusel, B., and Hefti, F. (1993) The nature of the trophic action of brain-derived neurotrophic factor, des(1-3)-insulin-like growth factor-1, and basic fibroblast growth factor on mesencephalic dopaminergic neurons developing in culture. Neuroscience, 52:855-866.
-
(1993)
Neuroscience
, vol.52
, pp. 855-866
-
-
Beck, K.D.1
Knusel, B.2
Hefti, F.3
-
4
-
-
0028795044
-
Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain
-
Beck, K.D., Valverde, J., Alexi, T., Poulsen, K., Moffat, B., Vandlen, R.A., Rosenthal, A., and Hefti, F. (1995) Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain. Nature, 373:339-341.
-
(1995)
Nature
, vol.373
, pp. 339-341
-
-
Beck, K.D.1
Valverde, J.2
Alexi, T.3
Poulsen, K.4
Moffat, B.5
Vandlen, R.A.6
Rosenthal, A.7
Hefti, F.8
-
5
-
-
0028030607
-
Possible mechanisms of action of (-)deprenyl and other MAO-B inhibitors in some neurologic and psychiatric disorders
-
Berry, M.D., Juorio, A.V., and Paterson, I.A. (1994) Possible mechanisms of action of (-)deprenyl and other MAO-B inhibitors in some neurologic and psychiatric disorders. Progress in Neurobiol., 44:141-161.
-
(1994)
Progress in Neurobiol.
, vol.44
, pp. 141-161
-
-
Berry, M.D.1
Juorio, A.V.2
Paterson, I.A.3
-
6
-
-
0027289608
-
L-deprenyl increases GFAP immunoreactivity selectively in activated astrocytes in rat brain
-
Biagini, G., Zoli, M., Fuxe, K., and Agnati, L.F. (1993) L-deprenyl increases GFAP immunoreactivity selectively in activated astrocytes in rat brain. NeuroReport, 4:955-958.
-
(1993)
NeuroReport
, vol.4
, pp. 955-958
-
-
Biagini, G.1
Zoli, M.2
Fuxe, K.3
Agnati, L.F.4
-
7
-
-
0028343249
-
The concept of astrocyte-kinetic drug in the treatment of neurodegenerative diseases: Evidence for L-deprenyl-induced activation of reactive astrocytes
-
Biagini, G., Frasoldati, A., Fuxe, K., and Agnati, L.F. (1994) The concept of astrocyte-kinetic drug in the treatment of neurodegenerative diseases: Evidence for L-deprenyl-induced activation of reactive astrocytes. Neurochem. Int., 25:17-22.
-
(1994)
Neurochem. Int.
, vol.25
, pp. 17-22
-
-
Biagini, G.1
Frasoldati, A.2
Fuxe, K.3
Agnati, L.F.4
-
8
-
-
0022365018
-
Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease
-
Birkmayer, W., Knoll, J., Riederer, P., Youdim, M.B.H., Hars, V., and Marton, J. (1985) Increased life expectancy resulting from addition of L-deprenyl to Madopar treatment in Parkinson's disease. J. Neural Transm. 64:113-127.
-
(1985)
J. Neural Transm.
, vol.64
, pp. 113-127
-
-
Birkmayer, W.1
Knoll, J.2
Riederer, P.3
Youdim, M.B.H.4
Hars, V.5
Marton, J.6
-
9
-
-
0026074120
-
(-)Deprenyl induces activities of both Superoxide dismutase and catalase but not of glutathione peroxidase in the striatum of young male rats
-
Carrillo, M.C., Kanai, S., Nokubo, M., and Kitani, K. (1991) (-)Deprenyl induces activities of both Superoxide dismutase and catalase but not of glutathione peroxidase in the striatum of young male rats. Life Sci., 48:517-521.
-
(1991)
Life Sci.
, vol.48
, pp. 517-521
-
-
Carrillo, M.C.1
Kanai, S.2
Nokubo, M.3
Kitani, K.4
-
10
-
-
0026740195
-
(-)Deprenyl increases activities of Superoxide dismutase and catalase in striatum but not in hippocampus: The sex- and age-related differences in the optimal dose in the rat
-
Carrillo, M.C., Kanai, S., Nokubo, M., Ivy, G.O., Sato, Y., and Kitani, K. (1992) (-)Deprenyl increases activities of Superoxide dismutase and catalase in striatum but not in hippocampus: The sex- and age-related differences in the optimal dose in the rat. Exp. Neurol., 116:286-294.
-
(1992)
Exp. Neurol.
, vol.116
, pp. 286-294
-
-
Carrillo, M.C.1
Kanai, S.2
Nokubo, M.3
Ivy, G.O.4
Sato, Y.5
Kitani, K.6
-
11
-
-
0025423171
-
The dependance of motoneurons on their target muscle during postnatal development of the mouse
-
Crews, L.L. and Wigston, D.J. (1990) The dependance of motoneurons on their target muscle during postnatal development of the mouse. J. Neurosci., 10:1643-1653.
-
(1990)
J. Neurosci.
, vol.10
, pp. 1643-1653
-
-
Crews, L.L.1
Wigston, D.J.2
-
12
-
-
0029964328
-
Protection of the aged substantia nigra of the rat against oxidative damage by (-)deprenyl
-
de la Cruz, C.P., Revilla, E., Steffen, V., Rodriguez-Gomez, J.A., Cano, J., and Machado, A. (1996a) Protection of the aged substantia nigra of the rat against oxidative damage by (-)deprenyl. Br. J. Pharmacol., 117:1756-1760.
-
(1996)
Br. J. Pharmacol.
, vol.117
, pp. 1756-1760
-
-
De La Cruz, C.P.1
Revilla, E.2
Steffen, V.3
Rodriguez-Gomez, J.A.4
Cano, J.5
Machado, A.6
-
13
-
-
0030065155
-
Oxidative inactivation of tyrosine hydroxylase in substantia nigra of aged rats
-
de la Cruz, C.P., Revilla, E., Venero, J.L., Ayala, A., Cano, J., and Machado, A. (1996b) Oxidative inactivation of tyrosine hydroxylase in substantia nigra of aged rats. Free Rad. Biol. Med., 20:53-61.
-
(1996)
Free Rad. Biol. Med.
, vol.20
, pp. 53-61
-
-
De La Cruz, C.P.1
Revilla, E.2
Venero, J.L.3
Ayala, A.4
Cano, J.5
Machado, A.6
-
14
-
-
0029068334
-
Synergy between growth factors and transmitters required for catecholamine differentiation in brain neurons
-
Du, X. and Iacovitti, L. (1995) Synergy between growth factors and transmitters required for catecholamine differentiation in brain neurons. J. Neurosci., 15:5420-5427.
-
(1995)
J. Neurosci.
, vol.15
, pp. 5420-5427
-
-
Du, X.1
Iacovitti, L.2
-
15
-
-
0024521368
-
Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture
-
Ferrari, G., Minozzi, M.C., Toffano, G., Leon, A., and Skaper, S.D. (1989) Basic fibroblast growth factor promotes the survival and development of mesencephalic neurons in culture. Devel. Biol., 133:140-147.
-
(1989)
Devel. Biol.
, vol.133
, pp. 140-147
-
-
Ferrari, G.1
Minozzi, M.C.2
Toffano, G.3
Leon, A.4
Skaper, S.D.5
-
16
-
-
0023481972
-
The neostriatal mosaic: II. Patch- And matrix-directed mesostriatal dopaminergic and non-dopaminergic systems
-
Gerfen, C.R., Herkenham, M., and Thibault, J. (1987) The neostriatal mosaic: II. Patch- and matrix-directed mesostriatal dopaminergic and non-dopaminergic systems. J. Neurosci. 7:3915-3934.
-
(1987)
J. Neurosci.
, vol.7
, pp. 3915-3934
-
-
Gerfen, C.R.1
Herkenham, M.2
Thibault, J.3
-
17
-
-
0018179394
-
Reversible reduction of tyrosine hydroxylase enzyme protein during the retrograde reaction in mesolimbic dopaminergic neurons
-
Gilad, G. and Teis, D.J. (1978) Reversible reduction of tyrosine hydroxylase enzyme protein during the retrograde reaction in mesolimbic dopaminergic neurons. Brain Res., 149:141-153.
-
(1978)
Brain Res.
, vol.149
, pp. 141-153
-
-
Gilad, G.1
Teis, D.J.2
-
18
-
-
0000051969
-
Long- and short-term regulation of tyrosine hydroxylase
-
F.E. Bloom and D.J. Kupfer, eds. Raven Press, New York
-
Goldstein, M. (1995) Long- and short-term regulation of tyrosine hydroxylase. In: Psychopharmacology: The Fourth Generation of Progress F.E. Bloom and D.J. Kupfer, eds. Raven Press, New York, pp. 189-195.
-
(1995)
Psychopharmacology: The Fourth Generation of Progress
, pp. 189-195
-
-
Goldstein, M.1
-
19
-
-
0026326710
-
A review of the pharmacology of selegiline
-
Heinonen, E.H. and Lammintausta, R. (1991) A review of the pharmacology of selegiline. Acta Neurol. Scand. 84, Suppl. 136:44-59.
-
(1991)
Acta Neurol. Scand.
, vol.84
, Issue.136 SUPPL.
, pp. 44-59
-
-
Heinonen, E.H.1
Lammintausta, R.2
-
20
-
-
0028127755
-
Neurotrophin-4/5 is a survival factor for embryonic midbrain dopaminergic neurons in enriched cultures
-
Hynes, M.A., Poulsen, K., Armanini, M., Berkemeier, L., Phillips, H., and Rosenthal, A. (1994) Neurotrophin-4/5 is a survival factor for embryonic midbrain dopaminergic neurons in enriched cultures. J. Neurosci. Res., 37:144-154.
-
(1994)
J. Neurosci. Res.
, vol.37
, pp. 144-154
-
-
Hynes, M.A.1
Poulsen, K.2
Armanini, M.3
Berkemeier, L.4
Phillips, H.5
Rosenthal, A.6
-
21
-
-
0025240761
-
Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury. I. Stimulation of hydrogen peroxide resistance
-
Jackson, G.R., Apffel, L., Werrbach-Perez, K., and Perez-Polo, J.K. (1990) Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury. I. Stimulation of hydrogen peroxide resistance. J. Neurosci. Res., 25:360-368.
-
(1990)
J. Neurosci. Res.
, vol.25
, pp. 360-368
-
-
Jackson, G.R.1
Apffel, L.2
Werrbach-Perez, K.3
Perez-Polo, J.K.4
-
22
-
-
0018128143
-
The possible mechanism of action of (-)deprenyl in Parkinson's disease
-
Knoll, J. (1978) The possible mechanism of action of (-)deprenyl in Parkinson's disease. J. Neural. Transm., 43:177-198.
-
(1978)
J. Neural. Transm.
, vol.43
, pp. 177-198
-
-
Knoll, J.1
-
23
-
-
0025265681
-
Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, and the insulin-like growth factors
-
Knusel, B., Michel, P.P., Schwaber, J., and Hefti, F. (1990) Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, and the insulin-like growth factors. J. Neurosci. 10:558-570.
-
(1990)
J. Neurosci.
, vol.10
, pp. 558-570
-
-
Knusel, B.1
Michel, P.P.2
Schwaber, J.3
Hefti, F.4
-
24
-
-
0026022504
-
Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin-3
-
Knusel, B., Winslow, J.W., Rosenthal, A., Burton, L.E., Seid, D.P., Nikolics, K., and Hefti, F. (1991) Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin-3. Proc. Natl. Acad. Sci. USA, 88:961-965.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 961-965
-
-
Knusel, B.1
Winslow, J.W.2
Rosenthal, A.3
Burton, L.E.4
Seid, D.P.5
Nikolics, K.6
Hefti, F.7
-
25
-
-
0026574673
-
Brain-derived neurotrophic factor administration protects basal forebrain cholinergic neurons but not nigral dopaminergic neurons from degenerative changes after axotomy in the adult rat brain
-
Knusel, B., Beck, K.D., Winslow, J.W., Rosenthal, A., Burton, L.E., Widmer, H.R., Nikolics, K., and Hefti, F. (1992) Brain-derived neurotrophic factor administration protects basal forebrain cholinergic neurons but not nigral dopaminergic neurons from degenerative changes after axotomy in the adult rat brain. J. Neurosci., 12:4391-4402.
-
(1992)
J. Neurosci.
, vol.12
, pp. 4391-4402
-
-
Knusel, B.1
Beck, K.D.2
Winslow, J.W.3
Rosenthal, A.4
Burton, L.E.5
Widmer, H.R.6
Nikolics, K.7
Hefti, F.8
-
26
-
-
0027401022
-
The pharmacology of Parkinson's disease therapy: An update
-
Kopin, I.J. (1993) The pharmacology of Parkinson's disease therapy: An update. Annu. Rev. Pharmacol. Toxicol., 32:467-495.
-
(1993)
Annu. Rev. Pharmacol. Toxicol.
, vol.32
, pp. 467-495
-
-
Kopin, I.J.1
-
27
-
-
0026564087
-
Specific irreversible monoamine oxidase B inhibitors stimulate gene expression of aromatic L-amino acid decarboxylase in PC12 cells
-
Li, X.M., Juorio, A.V., Paterson, I.A., Zhu, M.Y., and Boulton, A.A. (1992) Specific irreversible monoamine oxidase B inhibitors stimulate gene expression of aromatic L-amino acid decarboxylase in PC12 cells. J. Neurochem., 59:2324-2327.
-
(1992)
J. Neurochem.
, vol.59
, pp. 2324-2327
-
-
Li, X.M.1
Juorio, A.V.2
Paterson, I.A.3
Zhu, M.Y.4
Boulton, A.A.5
-
28
-
-
0028270158
-
Brain injury in a dish: A model for reactive gliosis
-
McMillian, M.K., Thai, L., Hong, J.S., O'Callagham, J.P., and Pennypacker, K.R. (1994) Brain injury in a dish: A model for reactive gliosis. Trends. Neurosci., 17:138-142.
-
(1994)
Trends. Neurosci.
, vol.17
, pp. 138-142
-
-
McMillian, M.K.1
Thai, L.2
Hong, J.S.3
O'Callagham, J.P.4
Pennypacker, K.R.5
-
29
-
-
0022394212
-
Deprenyl protects dopamine neurons from the neurotoxic effects of 1-methyl-4-phenylpyridinium ion
-
Mytilineou, C. and Cohen, G. (1985) Deprenyl protects dopamine neurons from the neurotoxic effects of 1-methyl-4-phenylpyridinium ion. J. Neurochem., 45:1951-1953.
-
(1985)
J. Neurochem.
, vol.45
, pp. 1951-1953
-
-
Mytilineou, C.1
Cohen, G.2
-
30
-
-
0026520111
-
NGF restores decrease in catalase activity and increases Superoxide dismutase and glutathione peroxidase activity in the brain of aged rats
-
Nistico, G., Ciriolo, M.R., Fiskin, K., Iannone, M., Martino, A., and Rotilio, G. (1992) NGF restores decrease in catalase activity and increases Superoxide dismutase and glutathione peroxidase activity in the brain of aged rats. Free Rad. Biol. Med., 12:177-181.
-
(1992)
Free Rad. Biol. Med.
, vol.12
, pp. 177-181
-
-
Nistico, G.1
Ciriolo, M.R.2
Fiskin, K.3
Iannone, M.4
Martino, A.5
Rotilio, G.6
-
31
-
-
84984144568
-
The effect of deprenyl (selegiline) on intra- And extraneuronal dopamine oxidation
-
Oreland, L., Arai, Y., and Stenstrom, A. (1983) The effect of deprenyl (selegiline) on intra- and extraneuronal dopamine oxidation. Acta Neurol. Scand. Suppl., 95:81-85.
-
(1983)
Acta Neurol. Scand. Suppl.
, vol.95
, pp. 81-85
-
-
Oreland, L.1
Arai, Y.2
Stenstrom, A.3
-
32
-
-
0024456653
-
Effect of deprenyl on the progression of disability in early Parkinson's disease
-
The Parkinson Study Group (1989) Effect of deprenyl on the progression of disability in early Parkinson's disease. N. Engl. J. Med., 321:1364-1371.
-
(1989)
N. Engl. J. Med.
, vol.321
, pp. 1364-1371
-
-
-
35
-
-
0025875460
-
Selegiline (deprenyl) treatment and death of nigral neurons in Parkinson's disease
-
Rinne, J.O., Roytta, M., Paljarvi, L., Rummukainen, J., and Rinne, U.K. (1991) Selegiline (deprenyl) treatment and death of nigral neurons in Parkinson's disease. Neurology, 41:859-861.
-
(1991)
Neurology
, vol.41
, pp. 859-861
-
-
Rinne, J.O.1
Roytta, M.2
Paljarvi, L.3
Rummukainen, J.4
Rinne, U.K.5
-
36
-
-
0343307081
-
Deprenyl induces the tyrosine hydroxylase enzyme in the rat dopaminergic nigrostriatal system
-
in press
-
Rodriguez-Gomez, J.A., and Venero, J.L., Vizuete, M.L., Cano, J., and Machado, A. Deprenyl induces the tyrosine hydroxylase enzyme in the rat dopaminergic nigrostriatal system. Mol. Brain. Res. (in press).
-
Mol. Brain. Res.
-
-
Rodriguez-Gomez, J.A.1
Venero, J.L.2
Vizuete, M.L.3
Cano, J.4
Machado, A.5
-
37
-
-
0027292598
-
Deprenyl increases survival of rat foetal nigral neurons in culture
-
Roy, E. and Bedard, P.J. (1993) Deprenyl increases survival of rat foetal nigral neurons in culture. NeuroReport, 4:1183-1186.
-
(1993)
NeuroReport
, vol.4
, pp. 1183-1186
-
-
Roy, E.1
Bedard, P.J.2
-
38
-
-
0026514670
-
Deprenyl reduces the death of motor neurons caused by axotomy
-
Salo, P.T. and Tatton, W.G. (1992) Deprenyl reduces the death of motor neurons caused by axotomy. J. Neurosci. Res., 31:394-400.
-
(1992)
J. Neurosci. Res.
, vol.31
, pp. 394-400
-
-
Salo, P.T.1
Tatton, W.G.2
-
39
-
-
0026469784
-
The antiparkinson efficacy of deprenyl derives from transient improvement that is likely to be symptomatic
-
Schulzer, M., Mak, E., and Calne, D.B. (1992) The antiparkinson efficacy of deprenyl derives from transient improvement that is likely to be symptomatic. Ann. Neural., 32:795-798.
-
(1992)
Ann. Neural.
, vol.32
, pp. 795-798
-
-
Schulzer, M.1
Mak, E.2
Calne, D.B.3
-
40
-
-
0026651994
-
Lesions of nigrostriatal pathway reduce expression of tyrosine hydroxylase gene in residual dopaminergic neurons of substantia nigra
-
Shirao, T., Evinger, M.J., Iacovitti, L., and Reis, D.J. (1992) Lesions of nigrostriatal pathway reduce expression of tyrosine hydroxylase gene in residual dopaminergic neurons of substantia nigra. Neurosci. Lett., 141:208-212.
-
(1992)
Neurosci. Lett.
, vol.141
, pp. 208-212
-
-
Shirao, T.1
Evinger, M.J.2
Iacovitti, L.3
Reis, D.J.4
-
42
-
-
0026689954
-
Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: Involvement of the glutathione system
-
Spina, M.B., Squinto, S.P., Miller, J., Lindsay, R.M., and Hyman, C. (1992) Brain-derived neurotrophic factor protects dopamine neurons against 6-hydroxydopamine and N-methyl-4-phenylpyridinium ion toxicity: Involvement of the glutathione system. J. Neurochem., 59:99-106.
-
(1992)
J. Neurochem.
, vol.59
, pp. 99-106
-
-
Spina, M.B.1
Squinto, S.P.2
Miller, J.3
Lindsay, R.M.4
Hyman, C.5
-
43
-
-
0026353406
-
Rescue of dying neurons: A new action for deprenyl in MPTP parkinsonism
-
Tatton, W.G. and Greenwood, C.E. (1991) Rescue of dying neurons: a new action for deprenyl in MPTP parkinsonism. J. Neurosci. Res., 30:666-672.
-
(1991)
J. Neurosci. Res.
, vol.30
, pp. 666-672
-
-
Tatton, W.G.1
Greenwood, C.E.2
-
44
-
-
0024343466
-
The effect of deprenyl (selegiline) on the natural history of Parkinson's disease
-
Tetrud, J.W. and Langston, J.W. (1989) The effect of deprenyl (selegiline) on the natural history of Parkinson's disease. Science, 41:519-522.
-
(1989)
Science
, vol.41
, pp. 519-522
-
-
Tetrud, J.W.1
Langston, J.W.2
-
45
-
-
0027504297
-
Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds
-
Tipton, K.F. and Singer, T.P. (1993) Advances in our understanding of the mechanisms of the neurotoxicity of MPTP and related compounds. J. Neurochem., 61:1191-1205.
-
(1993)
J. Neurochem.
, vol.61
, pp. 1191-1205
-
-
Tipton, K.F.1
Singer, T.P.2
-
46
-
-
0027173524
-
Protective effect of deprenyl against 1-methyl-4-phenylpyridinium neurotoxicity in rat striatum
-
Vizuete, M.L., Stoffen, V., Ayala, A., Cano, J., and Machado, A. (1993) Protective effect of deprenyl against 1-methyl-4-phenylpyridinium neurotoxicity in rat striatum. Neurosci. Lett., 152:113-116.
-
(1993)
Neurosci. Lett.
, vol.152
, pp. 113-116
-
-
Vizuete, M.L.1
Stoffen, V.2
Ayala, A.3
Cano, J.4
Machado, A.5
-
47
-
-
0028955389
-
Neuronal protective and rescue effects of deprenyl against MPP+ dopaminergic toxicity
-
Wu, R.M., Murphy, D.L., and Chiueh, C.C. (1995) Neuronal protective and rescue effects of deprenyl against MPP+ dopaminergic toxicity. J. Neural. Transm., 100:53-61.
-
(1995)
J. Neural. Transm.
, vol.100
, pp. 53-61
-
-
Wu, R.M.1
Murphy, D.L.2
Chiueh, C.C.3
|