Presynaptic inhibition via a phospholipase C- and phosphatidylinositol bisphosphate-dependent regulation of neuronal Ca2+ channels

Molecular Pharmacology

Volumn 68, Issue 5, 2005, Pages 1387-1396

  Lechner, Stefan G ^a   Hussl, Simon ^a   Schicker, Klaus W ^a   Drobny, Helmut ^a   Boehm, Stefan ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; BRADYKININ; BRADYKININ RECEPTOR; CADMIUM; CALCIUM CHANNEL; CALCIUM ION; DIOCTANOYL PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; ENZYME; NORADRENALIN; PEPTIDE; PERTUSSIS TOXIN; PHOSPHATE; PHOSPHOLIPASE A2 INHIBITOR; PHOSPHOLIPASE C; PHOSPHOLIPASE C INHIBITOR; POTASSIUM ION; PROTEIN KINASE C; RHO FACTOR; TRIPHOSPHOINOSITIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CONTROLLED STUDY; DEPOLARIZATION; ENZYME INHIBITION; INHIBITION KINETICS; NERVE CELL; NEWBORN; NONHUMAN; NORADRENALIN RELEASE; PIPETTE; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; RAT; RECORDING; REGULATORY MECHANISM; SUPERIOR CERVICAL GANGLION;

1-PHOSPHATIDYLINOSITOL 4-KINASE; ADENOSINE TRIPHOSPHATE; ANIMALS; BRADYKININ; CADMIUM; CALCIUM CHANNELS, N-TYPE; NOREPINEPHRINE; PERTUSSIS TOXIN; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHOLIPASE C; POTASSIUM; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PRESYNAPTIC; SUPERIOR CERVICAL GANGLION; SYNAPTIC TRANSMISSION;

EID: 27544456549     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.105.014886     Document Type: Article

References (40)

1. Balla T (1998) Phosphatidylinositol 4-kinases. Biochim Biophys Acta 1436:69-85.
2. Boehm S (1999) ATP stimulates sympathetic transmitter release via presynaptic P2X purinoceptors. J Neurosci 19:737-746.
3. 2+ channels. Neuroscience 69:221-231.
4. 2 bradykinin receptors. Br J Pharmacol 122:455-462.
5. Boehm S, Huck S, and Freissmuth M (1996) Involvement of a phorbol esterinsensitive protein kinase C in the alpha2-adrenergic inhibition of voltage-gated calcium current in chick sympathetic neurons. J Neurosci 16:4596-4603.
6. Boehm S and Kubista H (2002) Fine tuning of sympathetic transmitter release via ionotropic and metabotropic presynaptic receptors. Pharmacol Rev 54:43-99.
7. Bofill-Cardona E, Vartian N, Nanoff C, Freissmuth M, and Boehm S (2000) Two different signaling mechanisms involved in the excitation of rat sympathetic neurons by uridine nucleotides. Mol Pharmacol 57:1165-1172.
8. Burch RM and Axelrod J (1987) Dissociation of bradykinin-induced prostaglandin formation from phosphatidylinositol turnover in Swiss 3T3 fibroblasts: evidence for G protein regulation of phospholipase A2. Proc Natl Acad Sci USA 84:6374-6378.
9. Chuang HH, Prescott ED, Kong H, Shields S, Jordt SE, Basbaum AI, Chao MV, and Julius D (2001) Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. Nature (Lond) 411:957-962.
10. 2+ stores in rat sympathetic neurons. Proc Natl Acad Sci USA 95:7151-7156.
11. Edelbauer H, Lechner SG, Mayer M, Scholze T, and Boehm S (2005) Presynaptic inhibition of transmitter release from rat sympathetic neurons by bradykinin. J Neurochem 93:1110-1121.
12. Elmslie KS (2003) Neurotransmitter modulation of neuronal calcium channels. J Bioenerg Biomembr 35:477-489.
13. Filippov AK, Simon J, Barnard EA, and Brown DA (2003) Coupling of the nucleotide P2Y4 receptor to neuronal ion channels. Br J Pharmacol 138:400-406.
14. 2+ pools. Am J Physiol 268:C829-C837.
15. 2+ channels. J Neurosci 24:10980-10992.
16. Haley JE, Abogadie FC, Fernandez-Fernandez JM, Dayrell M, Vallis Y, Buckley NJ, and Brown DA (2000) Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4. J Neurosci 20:RC105.
17. Hille B (1994) Modulation of ion channel function by G protein-coupled receptors. Trends Neurosci 17:531-535.
18. Ikeda SR and Dunlap K (1999) Voltage-dependent modulation of N-type calcium channels: role of G protein subunits. Adv Second Messenger Phosphoprotein Res 33:131-151.
19. q/11. Neuron 14:400-405.
20. Just I, Selzer J, Wilm M, von Eichel-Streiber C, Mann M, and Aktories K (1995) Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature (Lond) 375:500-503.
21. Koh DS and Hille B (1997) Modulation by neurotransmitters of catecholamine secretion from sympathetic ganglion neurons detected by amperometry. Proc Natl Acad Sci USA 94:1506-1511.
22. Lister MD, Glaser KB, Ulevitch RJ, and Dennis EA (1989) Inhibition studies on the membrane-associated phospholipase A2 in vitro and prostaglandin E2 production in vivo of the macrophage-like P388D1 cell. Effects of manoalide, 7,7-dimethyl-5,8-eicosadienoic acid and p-bromophenacyl bromide. J Biol Chem 264:8520-8528.
23. Liu L, Roberts ML, and Rittenhouse AR (2004) Phospholipid metabolism is required for M1 muscarinic inhibition of N-type calcium current in sympathetic neurons. Eur Biophys J 33:255-264.
24. Micheva KD, Holz RW, and Smith SJ (2001) Regulation of presynaptic phosphatidylinositol 4,5-biphosphate by neuronal activity. J Cell Biol 154:355-368.
25. Nakanishi S, Catt KJ, and Balla T (1995) A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositolphospholipids. Proc Natl Acad Sci USA 92:5317-5321.
26. Schaefer T, Wiedemann C, Gitler C, and Burger MM (1994) Effects of arsenicals on the secretory process in chromaffin cells. Ann NY Acad Sci 710:356-367.
27. 2+-independent protein kinase C. J Neurosci 22:5823-5832.
28. 3H]norepinephrine release by activation of alpha-2 adrenergic receptors in cultured rat ganglion cells. Neuroscience 52:107-113.
29. Stevens CF (2004) Presynaptic function. Curr Opin Neurobiol 14:341-345.
30. Suh BC and Hille B (2002) Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis. Neuron 35:507-520.
31. Suh BC, Horowitz LF, Hirdes W, Mackie K, and Hille B (2004) Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq. J Gen Physiol 123:663-683.
32. Taverna E, Saba E, Rowe J, Francolini M, Clementi F, and Rosa P (2004) Role of lipid microdomains in P/Q-type calcium channel (Cav2.1) clustering and function in presynaptic membranes. J Biol Chem 279:5127-5134.
33. Vlahos CJ, Matter WF, Hui KY, and Brown RF (1994) A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY 294,002). J Biol Chem 269:5241-5248.
34. Wiedemann C, Schafer T, and Burger MM (1996) Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion. EMBO (Eur Mol Biol Organ) J 15:2094-2101.
35. Wiedemann C, Schafer T, Burger MM, and Sihra TS (1998) An essential role for a small synaptic vesicle-associated phosphatidylinositol 4-kinase in neurotransmitter release. J Neurosci 18:5594-5602.
36. Wilk-Blaszczak MA, Singer WD, Quill T, Miller B, Frost JA, Sternweis PC, and Belardetti F (1997) The monomeric G-proteins Rac1 and/or Cdc42 are required for the inhibition of voltage-dependent calcium current by bradykinin. J Neurosci 17:4094-4100.
37. Winks JS, Hughes S, Filippov AK, Tatulian L, Abogadie FC, Brown DA, and Marsh SJ (2005) Relationship between membrane phosphatidylinositol-4,5- bisphosphate and receptor-mediated inhibition of native neuronal M channels. J Neurosci 25:3400-3413.
38. 2. Nature (Lond) 419:947-952.
39. Xu C, Watras J, and Loew LM (2003) Kinetic analysis of receptor-activated phosphoinositide turnover. J Cell Biol 161:779-791.
40. 2 activates KCNQ channels and its hydrolysis underlies receptormediated inhibition of M currents. Neuron 37:963-975.