Loss of heterozygosity and somatic mutations of the Glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course

Cancer Research

Volumn 65, Issue 21, 2005, Pages 9712-9718

  Irving, Julie A E ^a   Minto, Lynne ^a   Bailey, Simon ^b   Hall, Andy G ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b ROYAL VICTORIA INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; CD19 ANTIGEN; CD34 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; ETOPOSIDE; GENOMIC DNA; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HLA DR ANTIGEN; METHOTREXATE; PREDNISOLONE; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ALLELE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BLAST CELL; BONE MARROW TRANSPLANTATION; CANCER PALLIATIVE THERAPY; CANCER RADIOTHERAPY; CHILD; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; CLONE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; EXON; GENE DELETION; GENE IDENTIFICATION; GENETIC SCREENING; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; LEUKEMIA RELAPSE; LEUKEMIA REMISSION; LIGAND BINDING; MICROSATELLITE MARKER; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SOMATIC MUTATION; WILD TYPE;

ALLELES; BONE MARROW; CELL LINE, TUMOR; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; EXONS; GENE DELETION; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; MUTATION; PREDNISOLONE; RECEPTORS, GLUCOCORTICOID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 27544446055     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-1227     Document Type: Article

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