Cross-talk among epidermal growth factor, Ap5A, and nucleotide receptors causing enhanced ATP Ca2+ signaling involves extracellular kinase activation in cerebellar astrocytes

Journal of Neuroscience Research

Volumn 81, Issue 6, 2005, Pages 789-796

  Delicado, Esmerilda G ^a   Jimȩnez, Ana I ^a   Carrasquero, Luz María G ^a   Castro, Enrique ^b   Miras Portugal, Ma Teresa ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

Author keywords

Calcium; Dinucleotides; ERK activation; Glia; Growth factors; Nucleotide receptors

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CALCIUM; DIADENOSINE PENTAPHOSPHATE; EPIDERMAL GROWTH FACTOR; HERBIMYCIN A; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN KINASE C; PROTEIN P21; RAS PROTEIN; WORTMANNIN;

ANIMAL CELL; ARTICLE; ASTROCYTE; CALCIUM CELL LEVEL; CELL ACTIVITY; CELL STIMULATION; CEREBELLUM; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CALCIUM SIGNALING; CELLS, CULTURED; CEREBELLUM; DINUCLEOSIDE PHOSPHATES; ENZYME ACTIVATION; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLUOROMETRY; ISOENZYMES; NUCLEOTIDES; PROTEIN KINASE C; RATS; RATS, WISTAR; RECEPTOR CROSS-TALK; RECEPTOR PROTEIN-TYROSINE KINASES; SRC-FAMILY KINASES;

EID: 27444444885     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.20609     Document Type: Article

References (42)

1. Braun N, Zhu Y, Krieglstein J, Culmsee C, Zimmermann H. 1998. Upregulation of enzyme chain hydrolyzing extracellular ATP following transient forebrain ischemia in the rat. J Neurosci 18:4891-4900.
2. 2U purinergic receptors in cultured astrocytes: regulation by PKC subtypes α, δ and θ. Glia 17:63-71.
3. i. J Biol Chem 276:41479-41485.
4. Cotrina ML, Lin JH-C, López-García JC, Naus CCG, Nedergaard M. 2000. ATP-mediated glia signalling. J Neurosci 20:2835-2844.
5. 11 signaling. J Biol Chem 276:5438-5444.
6. Delicado EG, Jiménez AI, Castro E, Miras-Portugal MT. 2001. Cerebellar astrocytes coexpress different purinoceptors: cross-talk between several transduction mechanisms. Drug Dev Res 52:114-121.
7. o-mediated signal transduction. J Cell Biol 153:491-501.
8. Franke H, Krügel U, Schmidt R, Grosche J, Reichenbach A, Illes P. 2001. P2 receptor-types involved in astrogliosis in vivo. Br J Pharmacol 134:1180-1189.
9. 2 receptors stimulate mitogen-activated protein kinase in human embryonic kidney-293 cells. Cross-talk between cyclic AMP and protein kinase C activation. J Biol Chem 274:5972-5980.
10. AC-receptor activate MAP kinase by a ras-independent pathway in rat C6 glioma. J Neurochem 78: 1325-1338.
11. Grynkiewicz G, Poenie M, Tsien RY. 1985. A new generation of calcium indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
12. Gschwendt M, Dieterich S, Rennecke J, Kittstein W, Mueller HJ, Johannes FJ. 1996. Inhibition of protein kinase C μ by various inhibitors. Differentiation from protein kinase C isozymes. FEBS Lett 392:77-80.
13. Gutkind JS. 1998. The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades. J Biol Chem 273:1839-1842.
14. Gysbers JW, Rathbone MP. 1996. GTP and guanosine synergistically enhance NGF-induced neurite outgrowth from PC12 cells. Int J Dev Neurosci 14:19-34.
15. Harada H, Chan CM, Loesch A, Unwin R, Burnstock G. 2000. Induction of proliferation and apoptotic cell death via P2Y and P2X receptors, respectively, in rat glomerular mesangial cells. Kidney Int 57:949-958.
16. Hawes BE, Luttrell LM, van Biesen T, Lefkowitz RJ. 1996. Phosphatidylinositol 3-kinase is an early intermediate in the Gβγ-mediated mitogen-activated protein kinase signaling pathway. J Biol Chem 271:12133-12136.
17. Hollopeter G, Jantzen H-M, Vincent D, Li G, England L, Ramakrishnan V, Yang R-B, Nurden P, Nurden A, Julius D, Conley PB. 2001. Identification of the platelet ADP receptor targeted by antithrombotic drugs. Nature 409:202-207.
18. i/o-coupled P2Y receptors. J Neurosci 21:1975-1982.
19. 2G in releasable granules. J Biol Chem 276:8904-8909.
20. Jiménez AI, Castro E, Delicado EG, Miras-Portugal MT. 1998. Potentiation of adenosine 5′-triphosphate calcium responses by diadenosine pentaphosphate in individual rat cerebellar astrocytes. Neurosci Lett 246:109-111.
21. 2B receptors stimulation and other signals coupled to Gs proteins in type-1 cerebellar astrocytes. Glia 26:119-128.
22. Jiménez AI, Castro E, Communi D, Boeynaems JM, Delicado EG, Miras-Portugal MT. 2000. Coexpression of several types of metabotropic nucleotide receptors in single cerebellar astrocytes. J Neurochem 75:2071-2079.
23. Jiménez AI, Castro E, Delicado EG, Miras-Portugal MT. 2002. Specific diadenosine pentaphosphate receptor coupled to extracellular regulated kinases in cerebellar astrocytes. J Neurochem 83:299-308.
24. John GR, Scemes E, Suadicani SO, Liu JSH, Charles PC, Lee SC, Spray DC, Brosnan CF. 1999. IL-1β differentially regulates calcium wave propagation between primary human fetal astrocytes via pathways involving P2 receptors and gap junction channels. Proc Natl Acad Sci U S A 96:11613-11618.
25. John GR, Simpson JE, Woodroofe MN, Lee SC, Brosnan CF. 2001. Extracellular nucleotides differentially regulate interleukin-1β signaling in primary human astrocytes: implications for inflammatory gene expression. J Neurosci 21:4134-4142.
26. Klepeis VE, Weinger I, Kaczmarek E, Trinkaus-Randall V. 2004. P2Y receptors paly a critical role in epithelial cell communication and migration. J Cell Biochem 93:1115-1133.
27. Lenz G, Gottfrie C, Luo Z, Avruch J, Rodnight R, Nie WJ, Kang Y, Neary JT. 2000. P2Y purinoceptor subtypes recruit different Mek activators in astrocytes. Br J Pharmacol 129:927-936.
28. Lenz G, Goncalves D, Luo Z, Avruch J, Rodnight R, Neary JT. 2001. Extracellular ATP stimulates an inhibitory pathway towards growth factor-induced cRaf-1 and MEKK activation in astrocyte cultures. J Neurochem 77:1001-1009.
29. Luttrell LM, Hawes BE, van Biesen T, Luttrell DK, Lansing TJ, Lefkowitz RJ. 1996. Role of c-Src tyrosine kinase in G protein-coupled receptor and Gβγ subunit-mediated activation of mitogen-activated protein kinases. J Biol Chem 271:19443-19450.
30. Martiny-Baron G, Kazanietz MG, Mischak H, Blumberg PM, Kochs G, Hug H, Marmé D, Schächtele C. 1993. Selective inhibition of protein kinase C isozymes by indolocarbazole Gö 6976. J Biol Chem 268:9194-9197.
31. 2+ signals mediated by P2X-type purinoceptors in cultured cerebellar Purkinje cells. J Neurosci 18:1704-1712.
32. Neary JT, Rathbone MP, Cattabeni F, Abbracchio MP, Burnstock G. 1996. Trophic actions of extracellular nucleotides and nucleosides on glial and neuronal cells. Trends Neurosci 19:13-18.
33. Neary JT, Kang Y, Bu Y, Yu E, Akong K, Peters CM. 1999. Mitogenic signaling by ATP/P2Y purinergic receptors in astrocytes: involvement of a calcium-independent PKC ERK pathway distinct from the PI-PLC-calcium pathway. J Neurosci 19:4211-4220.
34. Planas AM, Justicia C, Soriano MA, Ferrer I. 1998. Epidermal growth factor receptor in proliferating reactive glia following transient focal ischemia in the rat brain. Glia 23:120-129.
35. Ralevic V, Burnstock G. 1998. Receptor for purines and pyrimidines. Pharmacol Rev 50:413-492.
36. 1 receptor stimulate mitogen-activated protein kinases and induce apoptosis. J Biol Chem 276:16379-16390.
37. Short SM, Boyer JL, Juliano RL. 2000. Integrins regulate the linkage between upstream and downstream events in G protein-coupled receptor signaling to mitogen-activated protein kinase. J Biol Chem 275: 12970-12977.
38. 2 receptors by UTP and ATP stimulates mitogen-activated kinase activity through a pathway that involves related adhesion focal tyrosine kinase and protein kinase C. J Biol Chem 273:2653-2660.
39. Tan M, Xu X, Ohba M, Ogawa W, Cui M-Z. 2003. Thrombin rapidly induces protein kinase D phosphorylation, and protein kinase C δ mediates the activation. J Biol Chem 278:2824-2828.
40. 6 glioma cells via activation of Ras/Raf/MEK/MAPK pathway. Br J Pharmacol 129: 1481-1489.
41. 2+. Biochem J 374:281-296.
42. Widmann C, Gibson S, Jarpe MB, Johnson GL. 1999. Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol Rev 79:143-180.