-
1
-
-
0021796829
-
Diltiazem: A review of its pharmacological properties and therapeutic efficacy
-
M. Chaffman, and R.N. Brogden Diltiazem: a review of its pharmacological properties and therapeutic efficacy Drugs 29 1985 387 454
-
(1985)
Drugs
, vol.29
, pp. 387-454
-
-
Chaffman, M.1
Brogden, R.N.2
-
2
-
-
0028930754
-
Diltiazem: Ten years of clinical experience in the treatment of hypertension
-
M.R. Weir Diltiazem: ten years of clinical experience in the treatment of hypertension J Clin Pharmacol 35 1995 220 232
-
(1995)
J Clin Pharmacol
, vol.35
, pp. 220-232
-
-
Weir, M.R.1
-
3
-
-
0027181298
-
Pharmacokinetics and metabolism of diltiazem in healthy males and females following a single oral dose
-
P.K. Yeung, C. Prescott, C. Haddad, T.J. Montague, C. McGregor, and M.A. Quilliam Pharmacokinetics and metabolism of diltiazem in healthy males and females following a single oral dose Eur J Drug Metab Pharmacokinet 18 1993 199 206
-
(1993)
Eur J Drug Metab Pharmacokinet
, vol.18
, pp. 199-206
-
-
Yeung, P.K.1
Prescott, C.2
Haddad, C.3
Montague, T.J.4
McGregor, C.5
Quilliam, M.A.6
-
4
-
-
0025330414
-
Diltiazem: A reappraisal of its pharmacological properties and therapeutic use
-
M.M.-T. Buckley, S.M. Grant, K.L. Goa, D. McTabish, and E.M. Sorkin Diltiazem: a reappraisal of its pharmacological properties and therapeutic use Drugs 39 1990 757 806
-
(1990)
Drugs
, vol.39
, pp. 757-806
-
-
Buckley, M.M.-T.1
Grant, S.M.2
Goa, K.L.3
McTabish, D.4
Sorkin, E.M.5
-
5
-
-
0023006016
-
Hypotensive response of spontaneously hypertensive rats to centrally administered diltiazem and its metabolites: In relevance to the hypotensive action by oral administration
-
H. Narita, M. Otsuka, H. Yabana, and T. Nagao Hypotensive response of spontaneously hypertensive rats to centrally administered diltiazem and its metabolites: in relevance to the hypotensive action by oral administration J Pharmacobiodyn 9 1986 547 553
-
(1986)
J Pharmacobiodyn
, vol.9
, pp. 547-553
-
-
Narita, H.1
Otsuka, M.2
Yabana, H.3
Nagao, T.4
-
6
-
-
0031790624
-
Pharmacokinetics and hypotensive effect of diltiazem in rabbits: Comparison of diltiazem with its major metabolites
-
P.K. Yeung, J.D.Z. Feng, and S.J. Buckley Pharmacokinetics and hypotensive effect of diltiazem in rabbits: comparison of diltiazem with its major metabolites J Pharm Pharmacol 50 1998 1247 1253
-
(1998)
J Pharm Pharmacol
, vol.50
, pp. 1247-1253
-
-
Yeung, P.K.1
Feng, J.D.Z.2
Buckley, S.J.3
-
7
-
-
0025168996
-
Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem
-
L. Pichard, G. Gillet, I. Fabre, I. Dalet-Beluche, C. Bonfils, and J.P. Thenot Identification of the rabbit and human cytochromes P-450IIIA as the major enzymes involved in the N-demethylation of diltiazem Drug Metab Dispos 18 1990 711 719
-
(1990)
Drug Metab Dispos
, vol.18
, pp. 711-719
-
-
Pichard, L.1
Gillet, G.2
Fabre, I.3
Dalet-Beluche, I.4
Bonfils, C.5
Thenot, J.P.6
-
8
-
-
0023588109
-
Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man
-
P.B. Watkins, S.A. Wrighton, E.G. Schuetz, D.T. Molowa, and P.S. Guzelian Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man J Clin Invest 80 1987 1029 1036
-
(1987)
J Clin Invest
, vol.80
, pp. 1029-1036
-
-
Watkins, P.B.1
Wrighton, S.A.2
Schuetz, E.G.3
Molowa, D.T.4
Guzelian, P.S.5
-
9
-
-
0026537891
-
Heterogeneity of cytochrome P450IIIA expression in rat gut epithelia
-
J.C. Kolars, P. Schmiedlin-Ren, W.O. Dobbins, J. Schuetz, S.A. Wrighton, and P.B. Watkins Heterogeneity of cytochrome P450IIIA expression in rat gut epithelia Gastroenterology 102 1992 1186 1198
-
(1992)
Gastroenterology
, vol.102
, pp. 1186-1198
-
-
Kolars, J.C.1
Schmiedlin-Ren, P.2
Dobbins, W.O.3
Schuetz, J.4
Wrighton, S.A.5
Watkins, P.B.6
-
10
-
-
0029931772
-
First-pass metabolism of diltiazem in anesthetized rabbits: Role of extrahepatic organs
-
M. Lefebvre, W. Homsy, G. Caille, and P. du Souich First-pass metabolism of diltiazem in anesthetized rabbits: role of extrahepatic organs Pharm Res 13 1996 124 128
-
(1996)
Pharm Res
, vol.13
, pp. 124-128
-
-
Lefebvre, M.1
Homsy, W.2
Caille, G.3
Du Souich, P.4
-
11
-
-
0029609829
-
The site of absorption in the small intestine determines diltiazem bioavailability in the rabbit
-
W. Homsy, G. Caille, and P. du Souich The site of absorption in the small intestine determines diltiazem bioavailability in the rabbit Pharm Res 12 1995 1722 1726
-
(1995)
Pharm Res
, vol.12
, pp. 1722-1726
-
-
Homsy, W.1
Caille, G.2
Du Souich, P.3
-
12
-
-
0028945408
-
Metabolism of diltiazem in hepatic and extrahepatic tissues of rabbits: In vitro studies
-
W. Homsy, M. Lefebvre, G. Caille, and P. du Souich Metabolism of diltiazem in hepatic and extrahepatic tissues of rabbits: in vitro studies Pharm Res 12 1995 609 614
-
(1995)
Pharm Res
, vol.12
, pp. 609-614
-
-
Homsy, W.1
Lefebvre, M.2
Caille, G.3
Du Souich, P.4
-
13
-
-
0026050819
-
Pharmacokinetics of diltiazem and deacetyldiltiazem in rats
-
Y.H. Lee, M.H. Lee, and C.K. Shim Pharmacokinetics of diltiazem and deacetyldiltiazem in rats Int J Pharm 76 1991 71 76
-
(1991)
Int J Pharm
, vol.76
, pp. 71-76
-
-
Lee, Y.H.1
Lee, M.H.2
Shim, C.K.3
-
14
-
-
0024421664
-
Reversal mechanism of multidrug resistance by verapamil: Direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells
-
K. Yusa, and T. Tsuruo Reversal mechanism of multidrug resistance by verapamil: direct binding of verapamil to P-glycoprotein on specific sites and transport of verapamil outward across the plasma membrane of K562/ADM cells Cancer Res 49 1989 5002 5006
-
(1989)
Cancer Res
, vol.49
, pp. 5002-5006
-
-
Yusa, K.1
Tsuruo, T.2
-
15
-
-
0035290059
-
Active secretion and enterocytic drug metabolism barriers to drug absorption
-
V.J. Wacher, L. Salphati, and L.Z. Benet Active secretion and enterocytic drug metabolism barriers to drug absorption Adv Drug Deliv Rev 46 2001 89 102
-
(2001)
Adv Drug Deliv Rev
, vol.46
, pp. 89-102
-
-
Wacher, V.J.1
Salphati, L.2
Benet, L.Z.3
-
16
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
M.M. Gottesman, and I. Pastan Biochemistry of multidrug resistance mediated by the multidrug transporter Annu Rev Biochem 62 1993 385 427
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
17
-
-
9044252313
-
CYP3A-Like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin a in Caco-2 cells: Interaction between the two biochemical barriers to intestinal transport
-
L.S.L. Gan, M.A. Moseley, B. Khosla, P.F. Augustijns, T.P. Bradshaw, and R.W. Hendren CYP3A-Like cytochrome P450-mediated metabolism and polarized efflux of cyclosporin A in Caco-2 cells: interaction between the two biochemical barriers to intestinal transport Drug Metab Dispos 24 1996 344 349
-
(1996)
Drug Metab Dispos
, vol.24
, pp. 344-349
-
-
Gan, L.S.L.1
Moseley, M.A.2
Khosla, B.3
Augustijns, P.F.4
Bradshaw, T.P.5
Hendren, R.W.6
-
18
-
-
0031765907
-
Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics
-
V.H. Wacher, J.A. Silverman, Y. Zhang, and L.Z. Benet Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics J Pharm Sci 87 1998 1322 1330
-
(1998)
J Pharm Sci
, vol.87
, pp. 1322-1330
-
-
Wacher, V.H.1
Silverman, J.A.2
Zhang, Y.3
Benet, L.Z.4
-
19
-
-
0033007704
-
Effects of intestinal CYP3A4 and P-glycoprotein on oral drug absorption theoretical approach
-
K. Ito, H. Kusuhara, and Y. Sugiyama Effects of intestinal CYP3A4 and P-glycoprotein on oral drug absorption theoretical approach Pharm Res 16 1999 225 231
-
(1999)
Pharm Res
, vol.16
, pp. 225-231
-
-
Ito, K.1
Kusuhara, H.2
Sugiyama, Y.3
-
20
-
-
0033214408
-
Flavonoids and isoflavonoids - A gold mine for metabolic engineering
-
R.A. Dixon, and C.L. Steele Flavonoids and isoflavonoids - a gold mine for metabolic engineering Trends Plant Sci 4 1999 394 400
-
(1999)
Trends Plant Sci
, vol.4
, pp. 394-400
-
-
Dixon, R.A.1
Steele, C.L.2
-
21
-
-
0028318752
-
The correlation between active oxygens scavenging and antioxidative effects of flavonoids
-
Y. Hanasaki, S. Ogawa, and S. Fukui The correlation between active oxygens scavenging and antioxidative effects of flavonoids Free Radic Biol Med 16 1994 845 850
-
(1994)
Free Radic Biol Med
, vol.16
, pp. 845-850
-
-
Hanasaki, Y.1
Ogawa, S.2
Fukui, S.3
-
22
-
-
0024366081
-
Modulating effect of plant flavonoids on the mutagenicity of N-methyl-N′-nitro-N-nitrosoguanidine
-
A.R. Francis, T.K. Shetty, and R.K. Bhattacharya Modulating effect of plant flavonoids on the mutagenicity of N-methyl-N′-nitro-N- nitrosoguanidine Carcinogenesis 10 1989 1953 1955
-
(1989)
Carcinogenesis
, vol.10
, pp. 1953-1955
-
-
Francis, A.R.1
Shetty, T.K.2
Bhattacharya, R.K.3
-
23
-
-
0344255791
-
Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock
-
S.H. Fang, Y.C. Hou, W.C. Chang, S.L. Hsiu, P-D.L. Chao, and B.L. Chiang Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decreased the incidence of septic shock Life Sci 74 2003 743 756
-
(2003)
Life Sci
, vol.74
, pp. 743-756
-
-
Fang, S.H.1
Hou, Y.C.2
Chang, W.C.3
Hsiu, S.L.4
Chao, P-D.L.5
Chiang, B.L.6
-
24
-
-
0037154405
-
Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450
-
P. Hodek, P. Trefil, and M. Stiborova Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450 Chem Biol Interact 139 2002 1 21
-
(2002)
Chem Biol Interact
, vol.139
, pp. 1-21
-
-
Hodek, P.1
Trefil, P.2
Stiborova, M.3
-
25
-
-
0037371275
-
Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport
-
S. Zhang, and M.E. Morris Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport J Pharmacol Exp Ther 304 2003 1258 1267
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 1258-1267
-
-
Zhang, S.1
Morris, M.E.2
-
26
-
-
0025642924
-
Species comparison of pharmacokinetics and metabolism of diltiazem in humans, dogs, rabbits, and rats
-
P.K.F. Yeung, S.J. Mosher, M.A. Quilliam, and T.J. Montague Species comparison of pharmacokinetics and metabolism of diltiazem in humans, dogs, rabbits, and rats Drug Metab Dispos 18 1990 1055 1059
-
(1990)
Drug Metab Dispos
, vol.18
, pp. 1055-1059
-
-
Yeung, P.K.F.1
Mosher, S.J.2
Quilliam, M.A.3
Montague, T.J.4
-
27
-
-
0022411041
-
High performance liquid chromatographic determination of diltiazem and four of its metabolites in plasma
-
K.J. Goebel, and E.U. Kolle High performance liquid chromatographic determination of diltiazem and four of its metabolites in plasma J Chromatogr 345 1985 355 363
-
(1985)
J Chromatogr
, vol.345
, pp. 355-363
-
-
Goebel, K.J.1
Kolle, E.U.2
-
28
-
-
0142106303
-
Transporter-enzyme interactions: Implications for predicting drug-drug interactions from in vitro data
-
L.Z. Benet, C.L. Cummins, and C.Y. Wu Transporter-enzyme interactions: implications for predicting drug-drug interactions from in vitro data Curr Drug Metab 4 2003 393 398
-
(2003)
Curr Drug Metab
, vol.4
, pp. 393-398
-
-
Benet, L.Z.1
Cummins, C.L.2
Wu, C.Y.3
-
29
-
-
0036175307
-
Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4
-
C.L. Cummins, W. Jacobsen, and L.Z. Benet Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4 J Pharmacol Exp Ther 300 2002 1036 1045
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 1036-1045
-
-
Cummins, C.L.1
Jacobsen, W.2
Benet, L.Z.3
-
30
-
-
0027309055
-
P-glycoprotein-mediated transcellular transport of MDR-reversing agents
-
T. Saeki, K. Ueda, Y. Tanigawara, R. Hori, and T. Komano P-glycoprotein-mediated transcellular transport of MDR-reversing agents FEBS Lett 324 1993 99 102
-
(1993)
FEBS Lett
, vol.324
, pp. 99-102
-
-
Saeki, T.1
Ueda, K.2
Tanigawara, Y.3
Hori, R.4
Komano, T.5
-
31
-
-
0345073630
-
Profound difference in pharmacokinetics between morin and its isomer quercetin in rats
-
Y.C. Hou, P.D.L. Chao, H.J. Ho, C.C. Wen, and S.L. Hsiu Profound difference in pharmacokinetics between morin and its isomer quercetin in rats J Pharm Pharmacol 55 2003 199 203
-
(2003)
J Pharm Pharmacol
, vol.55
, pp. 199-203
-
-
Hou, Y.C.1
Chao, P.D.L.2
Ho, H.J.3
Wen, C.C.4
Hsiu, S.L.5
-
32
-
-
1442359716
-
Enhanced paclitaxel bioavailability after oral administration of paclitaxel or prodrug to rats pretreated with quercetin
-
J.S. Choi, B.W. Jo, and Y.C. Kim Enhanced paclitaxel bioavailability after oral administration of paclitaxel or prodrug to rats pretreated with quercetin Eur J Pharm Biopharm 57 2004 313 318
-
(2004)
Eur J Pharm Biopharm
, vol.57
, pp. 313-318
-
-
Choi, J.S.1
Jo, B.W.2
Kim, Y.C.3
-
33
-
-
10044220716
-
The effect of quercetin on the pharmacokinetics of verapamil and its major metabolite, norverapamil, in rabbits
-
J.S. Choi, and H.K. Han The effect of quercetin on the pharmacokinetics of verapamil and its major metabolite, norverapamil, in rabbits J Pharm Pharmacol 56 2004 1537 1542
-
(2004)
J Pharm Pharmacol
, vol.56
, pp. 1537-1542
-
-
Choi, J.S.1
Han, H.K.2
-
34
-
-
0037032676
-
Quercetin significantly decreased cyclosporin oral bioavailability in pigs and rats
-
S.L. Hsiu, Y.C. Hou, Y.H. Wang, C.W. Tsao, S.F. Su, and P.-D.L. Chao Quercetin significantly decreased cyclosporin oral bioavailability in pigs and rats Life Sci 72 2002 227 235
-
(2002)
Life Sci
, vol.72
, pp. 227-235
-
-
Hsiu, S.L.1
Hou, Y.C.2
Wang, Y.H.3
Tsao, C.W.4
Su, S.F.5
Chao, P.-D.L.6
-
35
-
-
0037465616
-
Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: Quercetin
-
J. Dupuy, G. Larrieu, J.F. Sutra, A. Lespine, and M. Alvinerie Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin Vet Parasitol 112 2003 337 347
-
(2003)
Vet Parasitol
, vol.112
, pp. 337-347
-
-
Dupuy, J.1
Larrieu, G.2
Sutra, J.F.3
Lespine, A.4
Alvinerie, M.5
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