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Volumn 4, Issue 10, 1999, Pages 394-400

Flavonoids and isoflavonoids - A gold mine for metabolic engineering

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMICROBIAL ACTIVITY; ANTISENSE TECHNOLOGY; BIOCHEMICAL PATHWAY; BIOSYNTHESIS; BIOTECHNOLOGY RESOURCES; DIET; ENZYME SPECIFICITY; FLAVONOID; HUMAN; METABOLIC ENGINEERING; NATURAL PRODUCT; PLANT MICROORGANISM INTERACTION; PROTEIN STRUCTURE; REGULATOR GENE; RHIZOSPHERE;

EID: 0033214408     PISSN: 13601385     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1360-1385(99)01471-5     Document Type: Review
Times cited : (625)

References (43)
  • 2
    • 0031613667 scopus 로고    scopus 로고
    • Bioavailability and health effects of dietary flavonols in man
    • Hollman P.C., Katan M.B. Bioavailability and health effects of dietary flavonols in man. Arch. Toxicol. 20(Suppl.):1998;237-248.
    • (1998) Arch. Toxicol. , vol.20 , Issue.SUPPL. , pp. 237-248
    • Hollman, P.C.1    Katan, M.B.2
  • 3
    • 0009695833 scopus 로고    scopus 로고
    • Spotlight on green tea extract
    • Khalsa K.P.S. Spotlight on green tea extract. Nutraceuticals World. 2:1999;52-54.
    • (1999) Nutraceuticals World , vol.2 , pp. 52-54
    • Khalsa, K.P.S.1
  • 4
    • 0030976331 scopus 로고    scopus 로고
    • Phyto-estrogens and western diseases
    • Adlercreutz H., Mazur W. Phyto-estrogens and western diseases. Ann. Med. 29:1997;95-120.
    • (1997) Ann. Med. , vol.29 , pp. 95-120
    • Adlercreutz, H.1    Mazur, W.2
  • 5
    • 0000876809 scopus 로고    scopus 로고
    • Isoflavonoids: Biochemistry, molecular biology, and biological functions
    • (Sankawa, U., ed.) Elsevier
    • Dixon, R.A. (1999) Isoflavonoids: biochemistry, molecular biology, and biological functions, in Comprehensive Natural Products Chemistry (Vol. 1) (Sankawa, U., ed.), pp. 773-823, Elsevier.
    • (1999) Comprehensive Natural Products Chemistry , vol.1 , pp. 773-823
    • Dixon, R.A.1
  • 6
    • 0025070571 scopus 로고
    • Activation, structure and organization of genes involved in microbial defense in plants
    • Dixon R.A., Harrison M.J. Activation, structure and organization of genes involved in microbial defense in plants. Adv. Genet. 28:1990;165-234.
    • (1990) Adv. Genet. , vol.28 , pp. 165-234
    • Dixon, R.A.1    Harrison, M.J.2
  • 7
    • 0026766340 scopus 로고
    • Rhizobium-plant signal exchange
    • Fisher R.F., Long S.R. Rhizobium-plant signal exchange. Nature. 387:1992;655-660.
    • (1992) Nature , vol.387 , pp. 655-660
    • Fisher, R.F.1    Long, S.R.2
  • 8
    • 0001193628 scopus 로고
    • Isoflavonoid accumulation and expression of defense gene transcripts during the establishment of vesicular arbuscular mycorrhizal associations in roots of Medicago truncatula
    • Harrison M.J., Dixon R.A. Isoflavonoid accumulation and expression of defense gene transcripts during the establishment of vesicular arbuscular mycorrhizal associations in roots of Medicago truncatula. Mol. Plant-Microbe Interact. 6:1993;643-654.
    • (1993) Mol. Plant-Microbe Interact. , vol.6 , pp. 643-654
    • Harrison, M.J.1    Dixon, R.A.2
  • 9
    • 0031956558 scopus 로고    scopus 로고
    • Maackiain detoxification contributes to the virulence of Nectria haematococca MP VI on chickpea
    • Enkerli J., Bhatt G., Covert S.F. Maackiain detoxification contributes to the virulence of Nectria haematococca MP VI on chickpea. Mol. Plant-Microbe Interact. 11:1998;317-326.
    • (1998) Mol. Plant-Microbe Interact. , vol.11 , pp. 317-326
    • Enkerli, J.1    Bhatt, G.2    Covert, S.F.3
  • 10
    • 0030458877 scopus 로고    scopus 로고
    • Transformation-mediated chromosome loss and disruption of a gene for pisatin demethylase decrease the virulence of Nectria haematococca on pea
    • Wasmann C.C., Van Etten H.D. Transformation-mediated chromosome loss and disruption of a gene for pisatin demethylase decrease the virulence of Nectria haematococca on pea. Mol. Plant-Microbe Interact. 9:1996;793-803.
    • (1996) Mol. Plant-Microbe Interact. , vol.9 , pp. 793-803
    • Wasmann, C.C.1    Van Etten, H.D.2
  • 11
    • 0030131133 scopus 로고    scopus 로고
    • Analysis of determinants of binding and transcriptional activation of the pisatin-responsive DNA binding factor of Nectria haematococca
    • He J., Ruan Y., Straney D. Analysis of determinants of binding and transcriptional activation of the pisatin-responsive DNA binding factor of Nectria haematococca. Mol. Plant-Microbe Interact. 9:1996;171-179.
    • (1996) Mol. Plant-Microbe Interact. , vol.9 , pp. 171-179
    • He, J.1    Ruan, Y.2    Straney, D.3
  • 12
    • 0029188479 scopus 로고
    • Flavonoids stimulate spore germination in Fusarium solani pathogenic on legumes in a manner sensitive to inhibitors of cAMP-dependent protein kinase
    • Ruan Y., Kotraiah V., Straney D.C. Flavonoids stimulate spore germination in Fusarium solani pathogenic on legumes in a manner sensitive to inhibitors of cAMP-dependent protein kinase. Mol. Plant-Microbe Interact. 8:1995;929-938.
    • (1995) Mol. Plant-Microbe Interact. , vol.8 , pp. 929-938
    • Ruan, Y.1    Kotraiah, V.2    Straney, D.C.3
  • 13
    • 0000615562 scopus 로고    scopus 로고
    • Chemotropic and contact responses of Phytophthora sojae hyphae to soybean isoflavonoids and artificial substrates
    • Morris P.F., Bone E., Tyler B.M. Chemotropic and contact responses of Phytophthora sojae hyphae to soybean isoflavonoids and artificial substrates. Plant Physiol. 117:1998;1171-1178.
    • (1998) Plant Physiol. , vol.117 , pp. 1171-1178
    • Morris, P.F.1    Bone, E.2    Tyler, B.M.3
  • 14
    • 0033011895 scopus 로고    scopus 로고
    • Dietary isoflavones: Biological effects and relevance to human health
    • Setchell K.D.R., Cassidy A. Dietary isoflavones: biological effects and relevance to human health. J. Nutr. 129:1999;758S-767S.
    • (1999) J. Nutr. , vol.129
    • Setchell, K.D.R.1    Cassidy, A.2
  • 15
    • 0029844446 scopus 로고    scopus 로고
    • Antioxidant activities of flavonoids as bioactive components of food
    • Rice-Evans C.A., Miller N.J. Antioxidant activities of flavonoids as bioactive components of food. Biochem. Soc. Trans. 24:1996;790-794.
    • (1996) Biochem. Soc. Trans. , vol.24 , pp. 790-794
    • Rice-Evans, C.A.1    Miller, N.J.2
  • 16
    • 0032437643 scopus 로고    scopus 로고
    • Dietary genistein: Perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat
    • Fritz W.A. et al. Dietary genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat. Carcinogenesis. 19:1998;2151-2158.
    • (1998) Carcinogenesis , vol.19 , pp. 2151-2158
    • Fritz, W.A.1
  • 17
    • 0010010107 scopus 로고    scopus 로고
    • Selective effects of genistein, a soybean isoflavone, on B-lymphopoiesis and bone loss caused by estrogen deficiency
    • Ishimi Y. et al. Selective effects of genistein, a soybean isoflavone, on B-lymphopoiesis and bone loss caused by estrogen deficiency. Endocrinology. 140:1999;1893-1900.
    • (1999) Endocrinology , vol.140 , pp. 1893-1900
    • Ishimi, Y.1
  • 18
    • 0040241878 scopus 로고    scopus 로고
    • A family of plant-specific polyketide synthases: Facts and predictions
    • Schröder J. A family of plant-specific polyketide synthases: facts and predictions. Trends Plant Sci. 2:1997;373-378.
    • (1997) Trends Plant Sci. , vol.2 , pp. 373-378
    • Schröder, J.1
  • 19
    • 0032569804 scopus 로고    scopus 로고
    • New pathway to polyketides in plants
    • Eckerman S. et al. New pathway to polyketides in plants. Nature. 396:1998;387-390.
    • (1998) Nature , vol.396 , pp. 387-390
    • Eckerman, S.1
  • 20
    • 0029240192 scopus 로고
    • Molecular cloning and heterologous expression of acridone synthase from elicited Ruta graveolens L. cell suspension cultures
    • Junghanns K.T. et al. Molecular cloning and heterologous expression of acridone synthase from elicited Ruta graveolens L. cell suspension cultures. Plant Mol. Biol. 27:1995;681-692.
    • (1995) Plant Mol. Biol. , vol.27 , pp. 681-692
    • Junghanns, K.T.1
  • 21
    • 0032805888 scopus 로고    scopus 로고
    • Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis
    • Ferrer J-L. et al. Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis. Nat. Struct. Biol. 6:1999;775-784.
    • (1999) Nat. Struct. Biol. , vol.6 , pp. 775-784
    • Ferrer, J.-L.1
  • 22
    • 0032518266 scopus 로고    scopus 로고
    • DNA shuffling of genes from diverse species accelerates directed evolution
    • Crameri A. et al. DNA shuffling of genes from diverse species accelerates directed evolution. Nature. 391:1998;288-291.
    • (1998) Nature , vol.391 , pp. 288-291
    • Crameri, A.1
  • 23
    • 0028814339 scopus 로고
    • Genetics and biochemistry of anthocyanin biosynthesis
    • Holton T.A., Cornish E.C. Genetics and biochemistry of anthocyanin biosynthesis. Plant Cell. 7:1995;1071-1083.
    • (1995) Plant Cell , vol.7 , pp. 1071-1083
    • Holton, T.A.1    Cornish, E.C.2
  • 24
    • 0032500379 scopus 로고    scopus 로고
    • CYP81E1, a cytochrome P450 cDNA of licorice (Glycyrrhiza echinata L.), encodes isoflavone 2′-hydroxylase
    • Akashi T., Aoki T., Ayabe S. CYP81E1, a cytochrome P450 cDNA of licorice (Glycyrrhiza echinata L.), encodes isoflavone 2′-hydroxylase. Biochem. Biophys. Res. Commun. 251:1998;67-70.
    • (1998) Biochem. Biophys. Res. Commun. , vol.251 , pp. 67-70
    • Akashi, T.1    Aoki, T.2    Ayabe, S.3
  • 25
    • 0033040462 scopus 로고    scopus 로고
    • Direct evidence for anthocyanidin synthase as a 2-oxoglutarate-dependent oxygenase: Molecular cloning and functional expression of cDNA from a red forma of Perilla frutescens
    • Saito K. et al. Direct evidence for anthocyanidin synthase as a 2-oxoglutarate-dependent oxygenase: molecular cloning and functional expression of cDNA from a red forma of Perilla frutescens. Plant J. 17:1999;181-189.
    • (1999) Plant J. , vol.17 , pp. 181-189
    • Saito, K.1
  • 26
    • 0032211998 scopus 로고    scopus 로고
    • CDNA cloning, gene expression and subcellular localization of anthocyanin 5-aromatic acyltransferase from Gentiana triflora
    • Fujiwara H. et al. cDNA cloning, gene expression and subcellular localization of anthocyanin 5-aromatic acyltransferase from Gentiana triflora. Plant J. 16:1998;421-431.
    • (1998) Plant J. , vol.16 , pp. 421-431
    • Fujiwara, H.1
  • 27
    • 0000677401 scopus 로고    scopus 로고
    • The functions and regulation of glutathione S-transferases in plants
    • Marrs K.A. The functions and regulation of glutathione S-transferases in plants. Annu. Rev. Plant Physiol. Plant Mol. Biol. 47:1996;127-158.
    • (1996) Annu. Rev. Plant Physiol. Plant Mol. Biol. , vol.47 , pp. 127-158
    • Marrs, K.A.1
  • 28
    • 0031172678 scopus 로고    scopus 로고
    • Vacuolar uptake of the phytoalexin medicarpin by the glutathione conjugate pump
    • Li Z-S. et al. Vacuolar uptake of the phytoalexin medicarpin by the glutathione conjugate pump. Phytochemistry. 45:1997;689-693.
    • (1997) Phytochemistry , vol.45 , pp. 689-693
    • Li, Z.-S.1
  • 29
    • 0032575879 scopus 로고    scopus 로고
    • Purification of 2-hydroxyisoflavanone dehydratase from the cell cultures of Pueraria lobata
    • Hakamatsuka T. et al. Purification of 2-hydroxyisoflavanone dehydratase from the cell cultures of Pueraria lobata. Phytochemistry. 49:1998;497-505.
    • (1998) Phytochemistry , vol.49 , pp. 497-505
    • Hakamatsuka, T.1
  • 30
    • 0033167088 scopus 로고    scopus 로고
    • Molecular characterization of the enzyme catalysing the aryl migration reaction of isoflavonoid biosynthesis in soybean
    • Steele C.L. et al. Molecular characterization of the enzyme catalysing the aryl migration reaction of isoflavonoid biosynthesis in soybean. Arch. Biochem. Biophys. 367:1999;147-150.
    • (1999) Arch. Biochem. Biophys. , vol.367 , pp. 147-150
    • Steele, C.L.1
  • 31
    • 0032541027 scopus 로고    scopus 로고
    • Identification of a cytochrome P450 cDNA encoding (2S)-flavanone 2-hydroxylase of licorice (Glycyrrhiza echinata L.; Fabaceae) which represents licodione synthase and flavone synthase II
    • Akashi T., Aoki T., Ayabe S-I. Identification of a cytochrome P450 cDNA encoding (2S)-flavanone 2-hydroxylase of licorice (Glycyrrhiza echinata L.; Fabaceae) which represents licodione synthase and flavone synthase II. FEBS Lett. 431:1998;287-290.
    • (1998) FEBS Lett. , vol.431 , pp. 287-290
    • Akashi, T.1    Aoki, T.2    Ayabe, S.-I.3
  • 32
    • 0031881338 scopus 로고    scopus 로고
    • Stress responses in alfalfa (Medicago sativa L.) XXII. cDNA cloning and characterization of an elicitor-inducible isoflavone 7-O-methyltransferase
    • He X-Z., Reddy J.T., Dixon R.A. Stress responses in alfalfa (Medicago sativa L.) XXII. cDNA cloning and characterization of an elicitor-inducible isoflavone 7-O-methyltransferase. Plant Mol. Biol. 36:1998;43-54.
    • (1998) Plant Mol. Biol. , vol.36 , pp. 43-54
    • He, X.-Z.1    Reddy, J.T.2    Dixon, R.A.3
  • 33
    • 0032725627 scopus 로고    scopus 로고
    • Transgene-mediated and elicitor-induced perturbation of metabolic channeling at the entry point into the phenyl propanoid pathway
    • Rasmussen S., Dixon R.A. Transgene-mediated and elicitor-induced perturbation of metabolic channeling at the entry point into the phenyl propanoid pathway. Plant Cell. 11:1999;1537-1552.
    • (1999) Plant Cell , vol.11 , pp. 1537-1552
    • Rasmussen, S.1    Dixon, R.A.2
  • 34
    • 0033582147 scopus 로고    scopus 로고
    • A cytochrome b(5) is required for full activity of flavonoid 3′,5′-hydroxylase, a cytochrome P450 involved in the formation of blue flower colors
    • deVetten N. et al. A cytochrome b(5) is required for full activity of flavonoid 3′,5′-hydroxylase, a cytochrome P450 involved in the formation of blue flower colors. Proc. Natl. Acad. Sci. U. S. A. 96:1999;778-783.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 778-783
    • DeVetten, N.1
  • 35
    • 0030185051 scopus 로고    scopus 로고
    • Novel anthocyanins produced in petals of genetically transformed lisianthus
    • Markham K.R. Novel anthocyanins produced in petals of genetically transformed lisianthus. Phytochemistry. 42:1996;1035-1038.
    • (1996) Phytochemistry , vol.42 , pp. 1035-1038
    • Markham, K.R.1
  • 36
    • 0031929267 scopus 로고    scopus 로고
    • Production of yellow colour in flowers: Redirection of flavonoid biosynthesis in Petunia
    • Davies K.M., Bloor S.J., Spiller G.B., Deroles S.C. Production of yellow colour in flowers: redirection of flavonoid biosynthesis in Petunia. Plant J. 13:1998;259-266.
    • (1998) Plant J. , vol.13 , pp. 259-266
    • Davies, K.M.1    Bloor, S.J.2    Spiller, G.B.3    Deroles, S.C.4
  • 37
    • 0001343256 scopus 로고    scopus 로고
    • Genetic manipulation of condensed tannins in higher plants. II. Analysis of birdsfoot trefoil plants harboring antisense dihydroflavonol reductase constructs
    • Robbins M.P. et al. Genetic manipulation of condensed tannins in higher plants. II. Analysis of birdsfoot trefoil plants harboring antisense dihydroflavonol reductase constructs. Plant Physiol. 116:1998;1133-1144.
    • (1998) Plant Physiol. , vol.116 , pp. 1133-1144
    • Robbins, M.P.1
  • 38
    • 0031039149 scopus 로고    scopus 로고
    • Biosynthesis of flavan-3-ols by leaf extracts of Onobrychis viciifolia
    • Singh S. et al. Biosynthesis of flavan-3-ols by leaf extracts of Onobrychis viciifolia. Phytochemistry. 44:1997;425-432.
    • (1997) Phytochemistry , vol.44 , pp. 425-432
    • Singh, S.1
  • 39
    • 0031772791 scopus 로고    scopus 로고
    • Engineering secondary metabolism in maize cells by ectopic expression of transcription factors
    • Grotewold E. et al. Engineering secondary metabolism in maize cells by ectopic expression of transcription factors. Plant Cell. 10:1998;721-740.
    • (1998) Plant Cell , vol.10 , pp. 721-740
    • Grotewold, E.1
  • 40
    • 0028725407 scopus 로고
    • Activation tagging: A means of isolating genes implicated as playing a role in plant growth and development
    • Walden R. et al. Activation tagging: a means of isolating genes implicated as playing a role in plant growth and development. Plant Mol. Biol. 26:1994;1521-1528.
    • (1994) Plant Mol. Biol. , vol.26 , pp. 1521-1528
    • Walden, R.1
  • 42
    • 0010396989 scopus 로고    scopus 로고
    • The maize Lc regulatory gene up-regulates the flavonoid biosynthetic pathway of Petunia
    • Bradley J.M. et al. The maize Lc regulatory gene up-regulates the flavonoid biosynthetic pathway of Petunia. Plant J. 13:1998;381-392.
    • (1998) Plant J. , vol.13 , pp. 381-392
    • Bradley, J.M.1
  • 43
    • 0033521719 scopus 로고    scopus 로고
    • Variation in the ability of the maize Lc regulatory gene to upregulate flavonoid biosynthesis in heterologous systems
    • Bradley J.M. et al. Variation in the ability of the maize Lc regulatory gene to upregulate flavonoid biosynthesis in heterologous systems. Plant Sci. 140:1999;31-39.
    • (1999) Plant Sci. , vol.140 , pp. 31-39
    • Bradley, J.M.1


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