메뉴 건너뛰기




Volumn 55, Issue 2, 2003, Pages 199-203

Profound difference in pharmacokinetics between morin and its isomer quercetin in rats

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; FLAVONOL DERIVATIVE; MORIN; MORIN GLUCURONIDE; MORIN SULFATE; QUERCETIN; QUERCETIN GLUCURONIDE; QUERCETIN SULFATE; UNCLASSIFIED DRUG;

EID: 0345073630     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/002235702487     Document Type: Article
Times cited : (61)

References (24)
  • 1
    • 0028366463 scopus 로고
    • Antiulcer and gastroprotective effects of quercetin: A gross and histologic study
    • Alarcon-De-La-Lastra, C., Martin, M. J., Motilva, V. (1994) Antiulcer and gastroprotective effects of quercetin: A gross and histologic study. Pharmacology 48: 56-62
    • (1994) Pharmacology , vol.48 , pp. 56-62
    • Alarcon-De-La-Lastra, C.1    Martin, M.J.2    Motilva, V.3
  • 2
    • 0029867672 scopus 로고    scopus 로고
    • Flavonoids - Chemistry, metabolism, cardioprotective effects, and dietary sources
    • Cook, N. C., Samman, S. (1996) Flavonoids - Chemistry, metabolism, cardioprotective effects, and dietary sources, J. Nutr. Biochem. 7: 66-76
    • (1996) J. Nutr. Biochem. , vol.7 , pp. 66-76
    • Cook, N.C.1    Samman, S.2
  • 3
    • 0028172728 scopus 로고
    • Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism
    • Critchfield, J. W., Welsh, C. J., Phang, J. M., Yeh, G. C. (1994) Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism. Biochem. Pharmacol. 48: 1437-1445
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1437-1445
    • Critchfield, J.W.1    Welsh, C.J.2    Phang, J.M.3    Yeh, G.C.4
  • 4
    • 0027939130 scopus 로고
    • Chemopreventive potential of dietary bioflavonoids against 20-methylcholanthrene-induced tumorigenesis
    • Elangovan, V., Sekar, N., Govindasamy, S. (1994) Chemopreventive potential of dietary bioflavonoids against 20-methylcholanthrene-induced tumorigenesis. Cancer Lett. 87: 107-113
    • (1994) Cancer Lett. , vol.87 , pp. 107-113
    • Elangovan, V.1    Sekar, N.2    Govindasamy, S.3
  • 5
    • 0029999052 scopus 로고    scopus 로고
    • Phase I clinical trial of the flavonoid quercetin: Pharmacokinetics and evidence for in vivo tyrosine kinase inhibition
    • Ferry, D. R., Smith, A., Malkhandi, J., Fyfe, D. W., DeTakats, P. G., Anderson, D., Baker, J., Kerr, D. J. (1996) Phase I clinical trial of the flavonoid quercetin: Pharmacokinetics and evidence for in vivo tyrosine kinase inhibition. Clin. Cancer Res. 2: 659-668
    • (1996) Clin. Cancer Res. , vol.2 , pp. 659-668
    • Ferry, D.R.1    Smith, A.2    Malkhandi, J.3    Fyfe, D.W.4    Detakats, P.G.5    Anderson, D.6    Baker, J.7    Kerr, D.J.8
  • 6
    • 0027504187 scopus 로고
    • Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study
    • Hertog, M. G. L., Feskens, E. J. M., Hollman, P. C. H., Katan, M. B., Kromhout, D. (1993) Dietary antioxidant flavonoids and risk of coronary heart disease: The Zutphen Elderly Study. Lancet 23: 1007-1011
    • (1993) Lancet , vol.23 , pp. 1007-1011
    • Hertog, M.G.L.1    Feskens, E.J.M.2    Hollman, P.C.H.3    Katan, M.B.4    Kromhout, D.5
  • 8
    • 0032819772 scopus 로고    scopus 로고
    • Dietary flavonoids: Intake, health effects and bioavailability
    • Hollman, P. C., Katan, M. B. (1999) Dietary flavonoids: Intake, health effects and bioavailability. Food Chem Toxicol. 37: 937-942
    • (1999) Food Chem Toxicol. , vol.37 , pp. 937-942
    • Hollman, P.C.1    Katan, M.B.2
  • 9
    • 0029790697 scopus 로고    scopus 로고
    • Role of dietary flavonoids in protection against cancer and coronary heart disease
    • Hollman, P. C., Hertog, M. G., Katan, M. B. (1996) Role of dietary flavonoids in protection against cancer and coronary heart disease. Biochem. Soc. Trans. 24: 785-789
    • (1996) Biochem. Soc. Trans. , vol.24 , pp. 785-789
    • Hollman, P.C.1    Hertog, M.G.2    Katan, M.B.3
  • 10
    • 0034878982 scopus 로고    scopus 로고
    • Determination of morin, quercetin and their conjugated metabolites in serum
    • Hsiu, S. L., Tsao, C. W., Tsai, Y. C., Ho, H. J., Chao, P. D. L. (2001) Determination of morin, quercetin and their conjugated metabolites in serum. Biol. Pharm. Bull. 24: 967-969
    • (2001) Biol. Pharm. Bull. , vol.24 , pp. 967-969
    • Hsiu, S.L.1    Tsao, C.W.2    Tsai, Y.C.3    Ho, H.J.4    Chao, P.D.L.5
  • 11
    • 0034202211 scopus 로고    scopus 로고
    • Antioxidants and cancer III: Quercetin
    • Lanson, D. W., Brignall, M. S. (2000) Antioxidants and cancer III: Quercetin. Altern. Med. Rev. 5: 196-208
    • (2000) Altern. Med. Rev. , vol.5 , pp. 196-208
    • Lanson, D.W.1    Brignall, M.S.2
  • 12
    • 0024947974 scopus 로고
    • Analysis and processing of Chinese herbal drugs VIII: The study of Sophorae Floe
    • Liu, I. M., Sheu, S. J. (1989) Analysis and processing of Chinese herbal drugs VIII: The study of Sophorae Floe. Am. J. Chin. Med. 17: 179-187
    • (1989) Am. J. Chin. Med. , vol.17 , pp. 179-187
    • Liu, I.M.1    Sheu, S.J.2
  • 14
    • 0033637140 scopus 로고    scopus 로고
    • The effect of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer
    • Middleton, E., Kandaswami, C., Theoharides, T. C. (2000) The effect of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol. Rev. 52: 673-651
    • (2000) Pharmacol. Rev. , vol.52 , pp. 673-751
    • Middleton, E.1    Kandaswami, C.2    Theoharides, T.C.3
  • 15
    • 0001954020 scopus 로고    scopus 로고
    • Quercetin: Nature's antihistamine
    • Murray, M. (1998) Quercetin: Nature's antihistamine. Better Nutr. 60: 10
    • (1998) Better Nutr. , vol.60 , pp. 10
    • Murray, M.1
  • 16
    • 0027380282 scopus 로고
    • Quercetin potentiates TNF-induced antiviral activity
    • Ohnishi, E., Bannai, H. (1993) Quercetin potentiates TNF-induced antiviral activity. Antiviral Res. 22: 327-331
    • (1993) Antiviral Res. , vol.22 , pp. 327-331
    • Ohnishi, E.1    Bannai, H.2
  • 21
    • 25444461103 scopus 로고
    • Plant flavonoids, especially tea flavonoids, are powerful anti-oxidants using an in vitro oxidation model for heart disease
    • Vinson, J. A., Dabbagh, Y. A., Serry, M. M., Jang, J. (1995) Plant flavonoids, especially tea flavonoids, are powerful anti-oxidants using an in vitro oxidation model for heart disease. J. Agric. Food Chem. 43: 2800-2802
    • (1995) J. Agric. Food Chem. , vol.43 , pp. 2800-2802
    • Vinson, J.A.1    Dabbagh, Y.A.2    Serry, M.M.3    Jang, J.4
  • 22
    • 0004080012 scopus 로고
    • Antioxidation of human low density lipoprotein by morin hydrate
    • Wu, T. W., Fung, K. P., Yang, C. C., Weisel, R. D. (1995a) Antioxidation of human low density lipoprotein by morin hydrate. Life Sci. 57: 51-56
    • (1995) Life Sci. , vol.57 , pp. 51-56
    • Wu, T.W.1    Fung, K.P.2    Yang, C.C.3    Weisel, R.D.4
  • 23
    • 0028812164 scopus 로고
    • Molecular properties and myocardial salvage effects of morin hydrate
    • Wu, T. W., Fung, K. P., Zeng, L. H., Wu, J. (1995b) Molecular properties and myocardial salvage effects of morin hydrate. Biochem. Pharmacol. 49: 537-573
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 537-543
    • Wu, T.W.1    Fung, K.P.2    Zeng, L.H.3    Wu, J.4
  • 24
    • 0028027249 scopus 로고
    • Morin hydrate protects cultured rat glomerular mesangial cells against oxyradical damage
    • Zeng, L. H., Fung, K. P., Wu, T. W. (1994) Morin hydrate protects cultured rat glomerular mesangial cells against oxyradical damage. Life Sci. 55: PL351-PL357
    • (1994) Life Sci. , vol.55
    • Zeng, L.H.1    Fung, K.P.2    Wu, T.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.