-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391:806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
-
2
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75:843-854.
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
3
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen CZ, Li L, Lodish HF, Bartel DP. MicroRNAs modulate hematopoietic lineage differentiation. Science 2004; 303:83-86.
-
(2004)
Science
, vol.303
, pp. 83-86
-
-
Chen, C.Z.1
Li, L.2
Lodish, H.F.3
Bartel, D.P.4
-
4
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin GA, Sevignani C, Dumitru CD, et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 2004; 101:2999-3004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
-
5
-
-
18744396337
-
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, Dumitru CD, Shimizu M, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2002; 99:15524-15529.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
-
6
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han J, et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003; 425:415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
-
7
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 2001; 409:363-366.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
8
-
-
0037144546
-
A microRNA in a multiple-turnover RNAi enzyme complex
-
Hutvagner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science 2002; 297:2056-2060.
-
(2002)
Science
, vol.297
, pp. 2056-2060
-
-
Hutvagner, G.1
Zamore, P.D.2
-
9
-
-
0035942736
-
Duplexes of 21 -nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, et al. Duplexes of 21 -nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411:494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
-
10
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
Song E, Lee SK, Wang J, et al. RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med 2003; 9:347-351.
-
(2003)
Nat Med
, vol.9
, pp. 347-351
-
-
Song, E.1
Lee, S.K.2
Wang, J.3
-
12
-
-
0346873025
-
Small interfering RNA inhibits hepatitis B virus replication in mice
-
Giladi H, Ketzinel-Gilad M, Rivkin L, et al. Small interfering RNA inhibits hepatitis B virus replication in mice. Mol Ther 2003; 8:769-776.
-
(2003)
Mol Ther
, vol.8
, pp. 769-776
-
-
Giladi, H.1
Ketzinel-Gilad, M.2
Rivkin, L.3
-
13
-
-
0141552295
-
Gene silencing by systemic delivery of synthetic siRNAs in adult mice
-
Sorensen DR, Leirdal M, Sioud M. Gene silencing by systemic delivery of synthetic siRNAs in adult mice. J Mol Biol 2003; 327:761-766.
-
(2003)
J Mol Biol
, vol.327
, pp. 761-766
-
-
Sorensen, D.R.1
Leirdal, M.2
Sioud, M.3
-
14
-
-
1942523210
-
In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats
-
Zhang Y, Boado RJ, Pardridge WM. In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats. J Gene Med 2003; 5:1039-1045.
-
(2003)
J Gene Med
, vol.5
, pp. 1039-1045
-
-
Zhang, Y.1
Boado, R.J.2
Pardridge, W.M.3
-
15
-
-
1142274208
-
Cdh1-APC controls axonal growth and patterning in the mammalian brain
-
Konishi Y, Stegmuller J, Matsuda T, et al. Cdh1-APC controls axonal growth and patterning in the mammalian brain. Science 2004; 303:1026-1030.
-
(2004)
Science
, vol.303
, pp. 1026-1030
-
-
Konishi, Y.1
Stegmuller, J.2
Matsuda, T.3
-
16
-
-
1942494048
-
Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA
-
Kishida T, Asada H, Gojo S, et al. Sequence-specific gene silencing in murine muscle induced by electroporation-mediated transfer of short interfering RNA. J Gene Med 2004; 6:105-110.
-
(2004)
J Gene Med
, vol.6
, pp. 105-110
-
-
Kishida, T.1
Asada, H.2
Gojo, S.3
-
17
-
-
0347089037
-
Electroporation and RNA interference in the rodent retina in vivo and in vitro
-
Matsuda T, Cepko CL. Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc Natl Acad Sci USA 2004; 101:16-22.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16-22
-
-
Matsuda, T.1
Cepko, C.L.2
-
18
-
-
0035900651
-
On the role of RNA amplification in dsRNA-triggered gene silencing
-
Sijen T, Fleenor J, Simmer F, et al. On the role of RNA amplification in dsRNA-triggered gene silencing. Cell 2001; 107:465-476.
-
(2001)
Cell
, vol.107
, pp. 465-476
-
-
Sijen, T.1
Fleenor, J.2
Simmer, F.3
-
19
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002; 296:550-553.
-
(2002)
Science
, vol.296
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
20
-
-
0036726313
-
Stable suppression of tumorigenicity by virus-mediated RNA interference
-
Brummelkamp TR, Bernards R, Agami R. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2002; 2:243-247.
-
(2002)
Cancer Cell
, vol.2
, pp. 243-247
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
21
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
Rubinson DA, Dillon CP, Kwiatkowski AV, et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nat Genet 2003; 33:401-406.
-
(2003)
Nat Genet
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
Dillon, C.P.2
Kwiatkowski, A.V.3
-
22
-
-
0037422583
-
Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5
-
Qin XF, An DS, Chen IS, Baltimore D, et al. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci USA 2003; 100:183-188.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 183-188
-
-
Qin, X.F.1
An, D.S.2
Chen, I.S.3
Baltimore, D.4
-
23
-
-
0036787671
-
Davidson BL siRNA-mediated gene silencing in vitro and in vivo
-
Xia H, Mao Q, Paulson HL. Davidson BL siRNA-mediated gene silencing in vitro and in vivo. Nat Biotechnol 2002; 20:1006-1010.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 1006-1010
-
-
Xia, H.1
Mao, Q.2
Paulson, H.L.3
-
24
-
-
0037948173
-
Generation of Ski-knockdown mice by expressing a long double-strand RNA from an RNA polymerase II promoter
-
Shinagawa T, Ishii S. Generation of Ski-knockdown mice by expressing a long double-strand RNA from an RNA polymerase II promoter. Genes Dev 2003; 17:1340-1345.
-
(2003)
Genes Dev
, vol.17
, pp. 1340-1345
-
-
Shinagawa, T.1
Ishii, S.2
-
25
-
-
6944238701
-
Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury
-
Hamar P, Song E, Kokeny G, et al. Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury. Proc Natl Acad Sci USA 2004; 101:14883-14888.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 14883-14888
-
-
Hamar, P.1
Song, E.2
Kokeny, G.3
-
26
-
-
21344454891
-
Exploring RNA interference as a therapeutic strategy for renal disease
-
Takabatake Y, Isaka Y, Mizui M, et al. Exploring RNA interference as a therapeutic strategy for renal disease. Gene Ther 2005; 12:965-973.
-
(2005)
Gene Ther
, vol.12
, pp. 965-973
-
-
Takabatake, Y.1
Isaka, Y.2
Mizui, M.3
-
27
-
-
21244463966
-
Small interfering RNA-mediated functional silencing of vasopressin V2 receptors in the mouse kidney
-
Hassan A, Tian Y, Zheng W, et al. Small interfering RNA-mediated functional silencing of vasopressin V2 receptors in the mouse kidney. Physiol Genomics 2005; 21:382-388.
-
(2005)
Physiol Genomics
, vol.21
, pp. 382-388
-
-
Hassan, A.1
Tian, Y.2
Zheng, W.3
-
28
-
-
0347623204
-
Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs)
-
Persengiev SP, Zhu X, Green MR. Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs). RNA 2004; 10:12-18.
-
(2004)
RNA
, vol.10
, pp. 12-18
-
-
Persengiev, S.P.1
Zhu, X.2
Green, M.R.3
-
29
-
-
0042972933
-
Activation of the interferon system by short-interfering RNAs
-
Sledz CA, Holko M, de Veer MJ, et al. Activation of the interferon system by short-interfering RNAs. Nat Cell Biol 2003; 5:834-839.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 834-839
-
-
Sledz, C.A.1
Holko, M.2
De Veer, M.J.3
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