Suppression of apoptosis and induction of DNA synthesis in vitro by the phthalate plasticizers monoethylhexylphthalate (MEHP) and diisononylphthalate (DINP): A comparison of rat and human hepatocytes in vitro

Archives of Toxicology

Volumn 73, Issue 8-9, 1999, Pages 451-456

  Hasmall, Susan C ^a   James, Neil H ^a   Macdonald, Neil ^a   West, Douglas ^a   Chevalier, Stephan ^a   Cosulich, Sabina C ^a   Roberts, Ruth A ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Apoptosis; Diethylhexylphthalate (DEHP); Diisononylphthalate (DINP); DNA synthesis; Peroxisome proliferation

Indexed keywords

CELL DNA; PEROXISOME PROLIFERATOR; PHTHALIC ACID 2 ETHYLHEXYL MONOESTER; PHTHALIC ACID DIISONONYL ESTER; PLASTICIZER; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA SYNTHESIS; FATTY ACID OXIDATION; HUMAN; HUMAN CELL; LIVER CARCINOGENESIS; LIVER CELL; MALE; METABOLIC ACTIVATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE;

ANIMALS; APOPTOSIS; CARCINOGENS; DIETHYLHEXYL PHTHALATE; DNA; DNA REPLICATION; HUMANS; LIVER; MALE; PHTHALIC ACIDS; PLASTICIZERS; RATS; RATS, INBRED F344; TRANSFORMING GROWTH FACTOR BETA;

EID: 0033428565     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050634     Document Type: Article

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