Identification, subviral localization, and functional characterization of the pseudorabies virus UL17 protein

Journal of Virology

Volumn 79, Issue 21, 2005, Pages 13442-13453

  Klupp, Barbara G ^a   Granzow, Harald ^a   Karger, Axel ^a   Mettenleiter, Thomas C ^a  

^a FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN RECOGNITION; ARTICLE; CELL LYSATE; DELETION MUTANT; DNA CLEAVAGE; DNA PACKAGING; ELECTRON MICROSCOPY; GENE; HERPES SIMPLEX VIRUS 1; IMMUNIZATION; IMMUNOGOLD LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PSEUDORABIES HERPETOVIRUS; UL17 GENE; VIRUS CAPSID; VIRUS CHARACTERIZATION; VIRUS IDENTIFICATION; VIRUS PARTICLE;

ANIMALS; CAPSID; CAPSID PROTEINS; CELL LINE; CELL NUCLEUS; DNA, VIRAL; ESCHERICHIA COLI; HERPESVIRUS 1, SUID; MICROSCOPY, IMMUNOELECTRON; RECOMBINANT PROTEINS; VIRUS REPLICATION;

ESCHERICHIA COLI; HUMAN HERPESVIRUS 1; MIRIDAE; ORYCTOLAGUS CUNICULUS; SUID HERPESVIRUS 1;

EID: 27144531191     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.21.13442-13453.2005     Document Type: Article

References (62)

1. Al-Kobaisi, M. F., F. J. Rixon, I. McDougall, and V. G. Preston. 1991. The herpes simplex virus UL33 gene product is required for the assembly of full capsids. Virology 180:380-388.
2. Baer, R., A. T. Bankier, M. D. Biggin, P. L. Deininger, P. J. Farrell, T. J. Gibson, G. F. Hatfull, G. S. Hudson, S. C. Satchwell, C. Seguin, P. Tuffnell, and B. G. Barrell. 1984. DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature (London) 310:207-211.
3. Baines, J. D., and S. K. Weller. 2005. Cleavage and packaging of herpes simplex virus 1 DNA. In C. E. Catalano (ed.), Viral genome packaging machines: genetics, structures, and mechanism. Landes Biosciences, Georgetown, Tex.
4. L15 gene product. J. Virol. 71:2666-2673.
5. Beard, P. M., and J. D. Baines. 2004. The DNA cleavage and packaging protein encoded by the UL33 gene of herpes simplex virus 1 associates with capsids. Virology 324:475-482.
6. L33 of herpes simplex virus type 1 form a complex in infected cells. J. Virol. 76:4785-4791.
7. Booy, F. P., W. W. Newcomb, B. L. Trus, J. C. Brown, T. S. Baker, and A. C. Steven. 1991. Liquid-crystalline, phage-like packaging of encapsidated DNA in herpes simplex virus. Cell 64:1007-1015.
8. Brack, A. R., B. G. Klupp, H. Granzow, R. Tirabassi, L. W. Enquist, and T. C. Mettenleiter. 2000. Role of the cytoplasmic tail of pseudorabies virus glycoprotein E in virion formation. J. Virol. 74:4004-4016.
9. Chee, M. S., A. T. Bankier, S. Beck, R, Bohni, C. M. Brown, R. Cerny, T. Horsnell, C. A. Hutchinson, T. Kouzarides, J. A. Martignetti, E. Preddie, S. C. Satchwell, P. Tomlinson, K. M. Weston, and B. G. Barrell. 1990. Analysis of the protein coding content of the sequence of human cytomegalovirus strain AD169. Curr. Top. Microbiol. Immunol. 154:125-169.
10. R cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinant. Gene 158:9-14.
11. Datsenko, K. A., and B. L. Wanner. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. USA 97:6640-6645.
12. Davison, A. J., B. L. Trus, N. Cheng, A. Steven, M. Watson, C. Cunningham, R.-M. LeDeuff, and T. Renault. 2005. A novel class of herpesvirus with bivalve hosts. J. Gen. Virol. 86:41-53.
13. Fuchs, W., H. Granzow, B. G. Klupp, M. Kopp, and T. C. Mettenleiter. 2002. The UL48 tegument protein of pseudorabies virus is critical for intracytoplasmic assembly of infectious virions. J. Virol. 76:6729-6742.
14. Gibson, W., and B. Roizman. 1972. Proteins specified by the herpes simplex virus. VIII. Characterization and composition of multiple capsid-forms of subtypes 1 and 2. J. Virol. 10:1044-1052.
15. Goshima, F., D. Watanabe, H. Takakuwa, K. Wada, T. Daikoku, M. Yamada, and Y. Nishiyama. 2000. Herpes simplex virus UL17 proteins is associated with B capsids and colocalizes with ICP35 and VP5 in infected cells. Arch. Virol. 145:417-426.
16. Graham, F. L., and A. J. van der Eb. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52:456-467.
17. Granzow, H., F. Weiland, A. Jöns, B. G. Klupp, A. Karger, and T. C. Mettenleiter. 1997. Ultrastructural analysis of the replication cycle of pseudorabies virus in cell culture: a reassessment. J. Virol. 71:2072-2082.
18. Granzow, H., B. G. Klupp, and T. C. Mettenleiter. 2004. Pseudorabies virus US3 protein is a component of primary and of mature virions. J. Virol. 78:1314-1323.
19. Granzow, H., B. G. Klupp, and T. C. Mettenleiter. 2005. Entry of pseudorabies virus: an immunogold labeling study. J. Virol. 79:3200-3205.
20. Granzow, H., B. G. Klupp, W. Fuchs, J. Veits, N. Osterrieder, and T. C. Mettenleiter. 2001. Egress of alphaherpesviruses: comparative ultrastructural study. J. Virol. 75:3675-3684.
21. Homa, F. L., and J. C. Brown. 1997. Capsid assembly and DNA packaging in herpes simplex virus. Rev. Med. Virol. 7:107-122.
22. Johannsen, E., M. Luftig, M. R. Chase, S. Weicksel, E. Cahir-McFarland, D. Illanes, D. Sarracino, and E. Kieff. 2004. Proteins of purified Epstein-Barr virus. Proc. Natl. Acad. Sci. USA 110:16286-16291.
23. Kaelin, K., S. Dezélée, M. J. Masse, F. Bras, and A. Flamand. 2000. The UL25 protein of pseudorabies virus associates with capsids and localizes to the nucleus and to microtubules. J. Virol. 74:474-482.
24. Kaplan, A. S., and A. E. Vatter. 1959. A comparison of herpes simplex and pseudorabies viruses. Virology 7:394-407.
25. Klupp, B. G., and T. C. Mettenleiter. 1999. Glycoprotein gL-independent infectivity of pseudorabies virus is mediated by a gD-gH fusion protein. J. Virol. 73:3014-3022.
26. Klupp, B. G., C. J. Hengartner, T. C. Mettenleiter, and L. W. Enquist. 2004. Complete, annotated sequence of the pseudorabies virus genome. J. Virol. 78:424-440.
27. Klupp, B. G., H. Granzow, E. Mundt, and T. C. Mettenleiter. 2001. Pseudorabies virus UL37 gene product is involved in secondary envelopment. J. Virol. 75:8927-8936.
28. Klupp, B. G., S. Böttcher, H. Granzow, M. Kopp, and T. C. Mettenleiter. 2005. Complex formation between the UL16 and UL21 tegument proteins of pseudorabies virus. J. Virol. 79:1510-1522.
29. Klupp, B. G., W. Fuchs, H. Granzow, R. Nixdorf, and T. C. Mettenleiter. 2002. The pseudorabies virus UL36 tegument protein physically interacts with the UL37 protein. J. Virol. 76:3065-3071.
30. Kopp, M., H. Granzow, W. Fuchs, B. G. Klupp, E. Mundt, A. Karger, and T. C. Mettenleiter. 2003. The pseudorabies virus UL11 protein is a virion component involved in secondary envelopment in the cytoplasm. J. Virol. 77:5339-5351.
31. Koslowski, K. M., P. R. Shaver, X.-Y. Wang, D. J. Tenney, and N. E. Pederson. 1997. The Pseudorabies virus UL28 protein enters the nucleus after coexpression with the herpes simplex virus UL15 protein. J. Virol. 71:9118-9123.
32. Laemmli, U. K. 1970. Cleavage of structural protein during the assembly of the head of bacteriophage T4. Nature 227:680-685.
33. Lamberti, C., and S. K. Weller. 1998. The herpes simplex virus type 1 cleavage/packaging protein, UL32, is involved in efficient localization of capsids to replication compartments. J. Virol. 72:2463-2473.
34. McGeoch, D. J., C. Cunningham, G. McIntyre, and A. Dolan. 1991. Comparative analysis of the long repeat regions and adjoining parts of the long unique regions in the genomes of herpes simplex viruses type 1 and 2. J. Gen. Virol. 72:3057-3075.
35. McLauchlan, J., and F. J. Rixon. 1992. Characterization of enveloped tegument structures (L-particles) produced by alphaherpesviruses: integrity of the tegument does not depend on the presence of capsid or envelope. J. Gen. Virol. 73:269-276.
36. McNab, A. R., P. Desai, S. Person, L. Roof, D. R. Thompson, W. W. Newcomb, J. C. Brown, and F. L. Homa. 1998. The product of the herpes simplex virus type 1 UL25 gene is required for encapsidation but not for cleavage of replicated viral DNA. J. Virol. 72:1060-1070.
37. Mettenleiter, T. C. 2000. Aujeszky's disease (pseudorabies) virus: the virus and molecular pathogenesis-state of the art, June 1999. Vet. Res. 31:99-115.
38. Mettenleiter, T. C. 2002. Herpesvirus assembly and egress. J. Virol. 76:1537-1547.
39. Mettenleiter, T. C. 2004. Budding events in herpesvirus morphogenesis. Virus Res. 106:167-180.
40. Mettenleiter, T. C., A. Saalmüller, and F. Weiland. 1993. Pseudorabies virus protein homologous to herpes simplex virus type 1 ICP18.5 is necessary for capsid maturation. J. Virol. 67:1236-1245.
41. Nakai, K., and P. Horton. 1999. PSORT: a program for detecting the sorting signals of proteins and predicting their subcellular localization. Trends Biochem. Sci. 24:34-35.
42. Newcomb, W. W., D. R. Thomsen, F. L. Homa, and J. C. Brown. 2003. Assembly of the herpes simplex virus capsid: identification of soluble scaffold-portal protein complexes and their role in formation of portal-containing capsids. J. Virol. 77:9862-9871.
43. Newcomb, W. W., F. L. Homa, D. R. Thomsen, Z. Ye, and J. C. Brown. 1994. Cell-free assembly of the herpes simplex virus capsid. J. Virol. 68:6059-6063.
44. Newcomb, W. W., R. M. Juhas, D. R. Thomsen, F. L. Homa, A. D. Burch, S. K. Weller, and J. C. Brown. 2001. The UL6 gene product forms the portal for entry of DNA into the herpesvirus capsid. J. Virol. 75:10923-10932.
45. Nixdorf, R., B. G. Klupp, A. Karger, and T. C. Mettenleiter. 2000. Effects of truncation of the carboxy terminus of pseudorabies virus glycoprotein B on infectivity. J. Virol. 74:7137-7145.
46. Patel, A. H., F. J. Rixon, C. Cunningham, and A. J. Davison. 1996. Isolation and characterization of herpes simplex type 1 mutants defective in the UL6 gene. Virology 217:111-123.
47. S3 proteins suggests specific roles in primary envelopment and egress of nucleocapsids. J. Virol. 76:8939-8952.
48. Roeder, G. S., and P. D. Sadowski. 1977. Bacteriophage T7 morphogenesis: phage-related particles in cells infected with wild-type and mutant T7 phage. Virology 76:263-285.
49. Roiztnan, B., and D. Knipe. 2001. Herpes simplex viruses and their replication, p. 2399-2459. In D. M. Knipe and P. M. Howley (ed.), Virology, 4th ed. Lippincott-Raven, Philadelphia, Pa.
50. L28 genes. J. Virol. 72:3045-3050.
51. L17 gene encodes virion tegument proteins that are required for cleavage and packaging of viral DNA. J. Virol. 72:3779-3788.
52. Sheaffer, A. K., W. W. Newcomb, M. Gao, D. Yu, S. K. Weller, J. C. Brown, and D. J. Tenney. 2001. Herpes simplex DNA cleavage and packaging proteins associated with the procapsid prior to its maturation. J. Virol. 75:687-698.
53. Stow, N. 2001. Packaging of genomic and amplicon DNA by the herpes simplex virus type 1 UL25-null mutant KUL25NS. J. Virol. 75:10755-10765.
54. Tatman, J. D., V. G. Preston, P. Nicholson, R. M. Elliott, and F. J. Rixon. 1994. Assembly of herpes simplex virus type 1 capsids using a panel of recombinant baculoviruses. J. Gen. Virol. 75:1101-1113.
55. Taus, N., B. Salmon, and J. D. Baines. 1998. The herpes simplex virus UL17 gene is required for localization of capsids and major and major capsid proteins to intranuclear sites where viral DNA is cleaved and packaged. Virology 252:115-125.
56. Tengelsen, L. A., N. E. Pedersen, P. R. Shaver, M. W. Whatten, and F. L. Homa. 1993. Herpes simplex virus type 1 DNA cleavage and encapsidation require the product of the UL28 gene: isolation and characterization of two UL28 deletion mutants. J. Virol. 67:3470-3480.
57. Thurlow, J. K., F. J. Rixon, M. Murphy, P. Targett-Adams, M. Hughes, and V. G. Preston. 2005. The herpes simplex virus type 1 DNA packaging protein UL17 is a virion protein that is present in both the capsid and the tegument compartments. J. Virol. 79:150-158.
58. Thomson, D. R., L. L. Roof, and F. L. Homa. 1994. Assembly of herpes simplex virus (HSV) intermediate capsids in insect cells infected with recombinant baculoviruses expressing HSV capsid proteins. J. Virol. 68:2442-2457.
59. Varnum, S. M., D. N. Streblow, M. E. Monroe, P. Smith, K. J. Auberry, L. Pasa-Tolic, D. Wang, K. Rodland, S. Wiley, W. Britt, T. Shenk, D. G. Camp, I. I., R. D. Smith, and J. A. Nelson. 2004. Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome. J. Virol. 78:10960-10966.
60. Veits, J., B. Köllner, J. P. Teifke, H. Granzow, T. C. Mettenleiter, and W. Fuchs. 2003. Isolation and characterization of monoclonal antibodies against structural proteins of infectious laryngotracheitis virus. Avian Dis. 47:330-342.
61. Yu, X. K., C. M. O'Connor, J. Altanasov, B. Damania, D. H. Kedes, and Z. H. Zhou. 2003. Three-dimensional structures of the A, B, and C capsids of rhesus monkey rhadinovirus: insights into gammaherpesvirus capsid assembly, maturation, and DNA packaging. J. Virol. 77:13182-13193.
62. Zhou, Z., D. Chen, J. Jakana, F. J. Rixon, and W. Chiu. 1999. Visualization of tegument-capsid interactions and DNA in intact herpes simplex virus type 1 virions. J. Virol. 73:3210-3218.