The herpes simplex virus type 1 cleavage/packaging protein, UL32, is involved in efficient localization of capsids to replication compartments

Journal of Virology

Volumn 72, Issue 3, 1998, Pages 2463-2473

  Lamberti, Carmela ^a   Weller, Sandra K ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; DNA BINDING PROTEIN; EPITOPE; VIRUS DNA;

ANIMAL CELL; ARTICLE; DNA PACKAGING; DNA REPLICATION ORIGIN; DNA SYNTHESIS; HERPES SIMPLEX VIRUS 1; IMMUNOBLOTTING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SOUTHERN BLOTTING; VIRION; VIRUS CAPSID; VIRUS GENOME; VIRUS MUTANT; VIRUS REPLICATION;

EID: 0031952179     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.3.2463-2473.1998     Document Type: Article

References (73)

1. Addison, C., F. J. Rixon, J. W. Palfreyman, M. O'Hara, and V. G. Preston. 1984. Characterisation of a herpes simplex virus type 1 mutant which has a temperature-sensitive defect in penetration of cells and assembly of capsids. Virology 138:246-259.
2. Addison, C., F. J. Rixon, and V. G. Preston. 1990. Herpes simplex virus type 1 UL28 gene product is important for the formation of mature capsids. J. Gen. Virol. 71:2377-2384.
3. Ali, M. A., B. Forghani, and E. M. Cantin. 1996. Characterization of an essential HSV-1 protein encoded by the UL25 gene reported to be involved in virus penetration and capsid assembly. Virology 216:278-283.
4. Al-Kobaisi, M. F., F. J. Rixon, I. McDougall, and V. G. Preston. 1991. The herpes simplex virus UL33 gene product is required for the assembly of full capsids. Virology 180:380-388.
5. Baines, J. D., C. Cunningbam, D. Nalwanga, and A. Davison. 1997. The UL15 gene of herpes simplex virus type 1 contains within its second exon a novel open reading frame that is translated in frame with the UL15 gene product. J. Virol. 71:2665-2673.
6. Baines, J. D., A. P. Poon, J. Rovnak, and B. Roizman. 1994. The herpes simplex virus 1 UL15 gene encodes two proteins and is required for cleavage of genomic viral DNA. J. Virol. 68:8118-8124.
7. Bataille, D., and A. Epstein. 1994. Herpes simplex virus replicative concatemers contain L components in inverted orientation. Virology 203:384-388.
8. Bazinet, C., and J. King. 1985. The DNA translocating vertex of dsDNA bacteriophage. Annu. Rev. Microbiol. 39:109-129.
9. Black, L. W. 1989. DNA packaging in ds DNA bacteriophages. Annu. Rev. Microbiol. 43:267-292.
10. Bush, M., D. R. Yager, M. Gao, K. Weisshart, A. I. Marcy, D. M. Coen, and D. M. Knipe. 1991. Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein. J. Virol. 65:1082-1089.
11. Casjens, S., and R. Hendrix. 1988. Control mechanism in dsDNA bacteriophage assembly, p. 15-91. In R. Calendar (ed.), The bacteriophages, vol. 1. Plenum Press, New York, N.Y.
12. Catalano, C. E., and M. A. Tomka. 1995. Role of gpFI protein in DNA packaging by bacteriophage lambda. Biochemistry 34:10036-10042.
13. Chang, Y. E., A. P. Poon, and B. Roizman. 1996. Properties of the protein encoded by the UL32 open reading frame of herpes simplex virus type 1. J. Virol. 70:3938-3946.
14. Coen, D. M., D. P. Aschman, P. T. Gelep, M. J. Retondo, S. K. Weller, and P. A. Schaffer. 1984. Fine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locus. J. Virol. 49:236-247.
15. Davison, A. J. 1992. Channel catfish virus: a new type of herpesvirus. Virology 186:9-14.
16. de Bruyn Kops, A., and D. M. Knipe. 1988. Formation of DNA replication structures in herpes virus-infected cells requires a viral DNA binding protein. Cell 55:857-868.
17. Desai, P., R. Ramakrishnan, Z. W. Lin, B. Osak, J. C. Glorioso, and M. Levine. 1993. The RR1 gene of herpes simplex virus type 1 is uniquely trans activated by ICP0 during infection. J. Virol. 67:6125-6135.
18. Dube, P., P. Tavares, R. Lurz, and M. van Heel. 1993. The portal protein of bacteriophage Spp1: a DNA pump with 13-fold symmetry. EMBO J. 12: 1303-1309.
19. Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction fragments to high specific activity. Anal. Biochem. 132:6-13.
20. Gibson, W., and B. Roizman. 1972. Proteins specified by herpes simplex virus. VIII. Characterization and composition of multiple capsid forms of subtypes 1 and 2. J. Virol. 10:1044-1052.
21. Goldstein, D. J., and S. K. Weller. 1988. Factor(s) present in herpes simplex virus type 1-infected cells can compensate for the loss of the large subunit of the viral ribonucleotide reductase: characterization of an ICP6 deletion mutant. Virology 166:41-51.
22. Goldstein, D. J., and S. K. Weller. 1988. Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: isolation and characterization of an ICP6 lacZ insertion mutant. J. Virol. 62:196-205.
23. Goldstein, D. J., and S. K. Weller. 1988. An ICP6::lacZ insertional mutagen is used to demonstrate that the UL52 gene of herpes simplex virus type 1 is required for virus growth and DNA synthesis. 3. Virol. 62:2970-2977.
24. Goodrich, L. D., P. A. Schaffer, D. I. Dorsky, C. S. Crumpacker, and D. S. Parris. 1990. Localization of the herpes simplex virus type 1 65-kilodalton DNA-binding protein and DNA polymerase in the presence and absence of viral DNA synthesis. J. Virol. 64:5738-5749.
25. Graham, F. L., and A. J. van der Eb. 1973. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52:456-467.
26. Knipe, D. M., D. Senechek, S. A. Rice, and J. L. Smith. 1987. Stages in the nuclear association of the herpes simplex virus transcriptional activator protein ICP4. J. Virol. 61:276-284.
27. Lamberti, C., and S. K. Weller. 1996. The herpes simplex virus type 1 UL6 protein is essential for cleavage and packaging but not for genomic inversion. Virology 226:403-407.
28. Lamberti, C., and S. K. Weller. Unpublished results.
29. Liptak, L. M., S. L. Uprichard, and D. M. Knipe. 1996. Functional order of assembly of herpes simplex virus DNA replication proteins into prereplicative structures. J. Virol. 70:1759-1767.
30. Lukonis, C. J., and S. K. Weller. 1996. Characterization of nuclear structures in cells infected with herpes simplex virus type 1 in the absence of viral DNA replication. J. Virol. 70:1751-1758.
31. Lukonis, C. J., and S. K. Weller. 1997. Formation of herpes simplex virus 1 replication compartments by transfection: requirements and localization to nuclear domain 10. J. Virol. 71:2390-2399.
32. Lukonis, C. J., and S. K. Weller. 1996. The herpes simplex virus type 1 transactivator ICP0 mediates aberrant intracellular localization of the viral helicase/primase complex subunits. Virology 220:495-501.
33. Malik, A. K., L. Shao, J. D. Shanley, and S. K. Weller. 1996. Intracellular localization of the herpes simplex virus type-1 origin binding protein, UL9. Virology 224:380-389.
34. Martinez, R., R. T. Sarisky, P. C. Weber, and S. K. Weller. 1996. Herpes simplex virus type 1 alkaline nuclease is required for efficient processing of viral DNA replication intermediates. J. Virol. 70:2075-2085.
35. Martinez, R. M., L. Shao, and S. K. Weller. 1992. The conserved helicase motifs of the herpes simplex virus type 1 origin-binding protein UL9 are important for function. J. Virol. 66:6735-6746.
36. Matusick-Kumar, L., P. J. McCann III, B. J. Robertson, W. W. Newcomb, J. C. Brown, and M. Gao. 1995. Release of the catalytic domain No from the herpes simplex virus type 1 protease is required for viral growth. J. Virol. 69:7113-7121.
37. McNab, A. R., P. Desai, S. Person, L. L. Roof, D. R. Thomsen, W. W. Newcomb, J. C. Brown, and F. L. Homa. 1998. The product of the herpes simplex virus type 1 UL25 gene is required for encapsidation but not for cleavage of replicated viral DNA. J. Virol. 72:1060-1070.
38. McVoy, M. A., and S. P. Adler. 1994. Human cytomegalovirus DNA replicates after early circularization by concatemer formation, and inversion occurs within the concatemer. J. Virol. 68:1040-1051.
39. Mosig, G., D. Ghosal, and S. Bock. 1981. Interactions between the maturation protein gp17 and the single-stranded DNA binding protein gp32 initiate DNA packaging and compete with initiation of secondary DNA replication forks in phage T4. Prog. Clin. Biol. Res. 64:139-150.
40. Murialdo, H., and D. Tzamtzis. 1997. Mutations of the coat protein gene of bacteriophage lambda that overcome the necessity for the FI gene; the EFi domain. Mol. Microbiol. 24:341-353.
41. 40a. Newcomb, W. W., and J. C. Brown. Personal communication.
42. Newcomb, W. W., F. L. Homa, D. R. Thomsen, F. P. Booy, B. L. Trus, A. C. Steven, J. V. Spencer, and J. C. Brown. 1996. Assembly of the herpes simplex virus capsid: characterization of intermediates observed during cell-free capsid formation. J. Mol. Biol. 263:432-446.
43. Newcomb, W. W., F. L. Homa, D. R. Thomsen, Z. Ye, and J. C. Brown. 1994. Cell-free assembly of the herpes simplex virus capsid. J. Virol. 68:6059-6063.
44. Olivo, P. D., N. J. Nelson, and M. D. Challberg. 1989. Herpes simplex virus type 1 gene products required for DNA replication: identification and over-expression. J. Virol. 63:196-204.
45. Patel, A. H., and J. B. Maclean. 1995. The product of UL6 gene of herpes simplex virus type 1 is associated with virus capsids. Virology 206:465-478.
46. Patel, A. H., F. J. Rixon, C. Cunningham, and A. J. Davison. 1996. Isolation and characterization of herpes simplex virus type 1 mutants defective in the UL6. Virology 217:111-123.
47. Perdue, M. L., J. C. Cohen, C. C. Randall, and D. J. O'Callaghan. 1976. Biochemical studies of the maturation of herpesvirus nucleocapsid species. Virology 74:194-208,
48. Phelan, A., J. Dunlop, A. H. Patel, N. D. Stow, and J. B. Clements. 1997. Nuclear sites of herpes simplex virus type 1 DNA replication and transcription colocalize at early times postinfection and are largely distinct from RNA processing factors. J. Virol. 71:1124-1132.
49. L15 open reading frame of herpes simplex virus 1. J. Virol. 67:4497-4503.
50. Quinlan, M. P., L. B. Chen, and D. M. Knipe. 1984. The intranuclear location of a herpes simplex virus DNA-binding protein is determined by the status of viral DNA replication. Cell 36:857-868.
51. Randall, R. E. 1986. Intranuclear localization of herpes simplex virus immediate-early and delayed-early proteins: evidence that ICP4 is associated with progeny virus DNA. J. Gen. Virol. 67:2163-2177.
52. Schaffer, P. A., G. M. Aron, N. Biswal, and M. Benyesh-Melnick. 1973. Temperature-sensitive mutants of herpes simplex virus type 1: isolation, complementation and partial characterization. Virology 52:57-71.
53. Severini, A., A. R. Morgan, D. R. Tovell, and L. J. Tyrrel. 1994. Study of the structure of replicative intermediates of HSV-1 DNA by pulsed-field gel electrophoresis. Virology 200:428-435.
54. Shelton, L. S. G., A. G. Albright, W. T. Ruyechan, and F. J. Jenkins. 1994. Retention of the herpes simplex virus type 1 (HSV-1) UL37 protein on single-stranded DNA columns requires the HSV-1 ICP8. J Virol 68:521-525.
55. Sherman, G., and S. Bachenheimer. 1987. DNA processing in temperature-sensitive morphogenic mutants of HSV-1. Virology 158:427-430.
56. Sherman, G., and S. L. Bachenheimer. 1988. Characterization of intranuclear capsids made by ts morphogenic mutants of HSV-1 Virology 163:471-480.
57. Steven, A. C., and P. G. Spear. 1996. Herpesvirus capsid assembly and envelopment. In R. Burnet, W. Chiu, and R. Garcea (ed.), Structural biology of viruses. Oxford University Press, New York, N.Y.
58. Sze, P., and R. C. Herman. 1992. The herpes simplex virus type 1 ICP6 gene is regulated by a leaky early promoter. Virus Res. 26:141-152.
59. Szilagyi, J. F., and C. Cunningham. 1991. Identification and characterization of a novel non-infectious herpes simplex virus-related particle. J. Gen. Virol. 72:661-668.
60. Tengelsen, L. A., N. E. Pederson, P. R. Shaver, M. W. Wathen, and F. L. Homa. 1993. Herpes simplex virus type 1 DNA cleavage and encapsidation require the product of the UL28 gene: isolation and characterization of two UL28 deletion mutants. J. Virol. 67:3470-3480.
61. Thomsen, D. R., L. L. Roof, and F. L. Homa. 1994. Assembly of herpes simplex virus (HSV) intermediate capsids in insect cells infected with recombinant baculoviruses expressing HSV capsid proteins. J. Virol. 68:2442-2457.
62. Towbin, H., T. Staehlein, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76:4350-4354.
63. Trus, B. L., F. P. Booy, W. W. Newcomb, J. C. Brown, F. L. Homa, D. R. Thomsen, and A. C. Steven. 1996. The herpes simplex virus capsid: structure, conformational changes upon maturation, and roles of the triplex proteins VP19c and VP23 in assembly. J. Mol. Biol. 263:447-462.
64. Trus, B. L., W. W. Newcomb, F. P. Booy, J. C. Brown, and A. C. Steven. 1992. Distinct monoclonal antibodies separately label the hexons or the pentons of herpes simplex virus capsid. Proc. Natl. Acad. Sci. USA 89:11508-11512.
65. Ward, P. L., W. O. Ogle, and B. Roizman. 1996. Assemblons: nuclear structures defined by aggregation of immature capsids and some tegument proteins of herpes simplex virus 1. J. Virol. 70:4623-4631.
66. Weller, S. K., D. P. Aschman, W. R. Sacks, D. M. Coen, and P. A. Schaffer. 1983. Genetic analysis of temperature-sensitive mutants of HSV-1: the combined use of complementation and physical mapping for cistron assignment. Virology 130:290-305.
67. Weller, S. K., E. P. Carmichael, D. P. Aschman, D. J. Goldstein, and P. A. Schaffer. 1987. Genetic and phenotypic characterization of mutants in four essential genes that map to the left half of HSV-1 UL DNA. Virology 161:198-210.
68. L, a herpes simplex virus type 1 origin of DNA synthesis. Mol. Cell. Biol. 5:930-942.
69. Yu, D., A. K. Sheaffer, D. J. Tenney, and S. K. Weller. 1997. Characterization of ICP6::lacZ insertion mutants of the UL15 gene of herpes simplex virus type 1 reveals the translation of two proteins. J. Virol. 71:2656-2665.
70. Yu, D., and S. K. Weller. Unpublished results.
71. Zhang, X., S. Efstathiou, and A. Simmons. 1994. Identification of novel herpes simplex virus replicative intermediates by field inversion gel electrophoresis: implications for viral DNA amplification strategies. Virology 202: 530-539.
72. Zhu, L., and S. K. Weller. 1992. The UL5 gene of herpes simplex virus type 1: isolation of a lacZ insertion mutant and association of the UL5 gene product with other members of the helicase-primase complex. J. Virol. 66: 458-468.
73. Zhu, L., and S. K. Weller. 1988. UL5, a protein required for HSV DNA synthesis: genetic analysis, overexpression in Escherichia coli, and generation of polyclonal antibodies. Virology 166:366-378.