-
1
-
-
0028018268
-
The ubiquitin-proteasome proteolytic pathway
-
Ciechanover, A. (1994) The ubiquitin-proteasome proteolytic pathway. Cell 79, 13-21
-
(1994)
Cell
, vol.79
, pp. 13-21
-
-
Ciechanover, A.1
-
2
-
-
2342667387
-
The development of proteasome inhibitors as anticancer drugs
-
Adams, J. (2004) The development of proteasome inhibitors as anticancer drugs. Cancer Cell 5, 417-421
-
(2004)
Cancer Cell
, vol.5
, pp. 417-421
-
-
Adams, J.1
-
3
-
-
0033529596
-
The proteasome, a novel protease regulated by multiple mechanisms
-
DeMartino, G.N. & Slaughter, C.A. (1999) The proteasome, a novel protease regulated by multiple mechanisms. J. Biol. Chem. 274, 22123-22126
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 22123-22126
-
-
DeMartino, G.N.1
Slaughter, C.A.2
-
4
-
-
0030905981
-
New insights into the mechanisms and importance of the proteasome in intracellular protein degradation
-
Goldberg, A.L., Akopian, T.N., Kisselev, A.F., Lee, D.H. & Rohrwild, M. (1997) New insights into the mechanisms and importance of the proteasome in intracellular protein degradation. Biol. Chem. 378, 131-140
-
(1997)
Biol. Chem.
, vol.378
, pp. 131-140
-
-
Goldberg, A.L.1
Akopian, T.N.2
Kisselev, A.F.3
Lee, D.H.4
Rohrwild, M.5
-
5
-
-
0027980321
-
The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB
-
Palombella, V.J., Rando, O.J., Goldberg, A.L. & Maniatis, T. (1994) The ubiquitin-proteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB. Cell 78, 773-785
-
(1994)
Cell
, vol.78
, pp. 773-785
-
-
Palombella, V.J.1
Rando, O.J.2
Goldberg, A.L.3
Maniatis, T.4
-
6
-
-
0036624741
-
Biologic sequelae of nuclear factor-κB blockade in multiple myeloma: Therapeutic applications
-
Mitsiades, N., Mitsiades, C.S., Poulaki, V., Chauhan, D., Richardson, P.G., Hideshima, T., Munshi, N., Treon, S.P. & Anderson, K.C. (2002) Biologic sequelae of nuclear factor-κB blockade in multiple myeloma: therapeutic applications. Blood 99, 4079-4086
-
(2002)
Blood
, vol.99
, pp. 4079-4086
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Richardson, P.G.5
Hideshima, T.6
Munshi, N.7
Treon, S.P.8
Anderson, K.C.9
-
7
-
-
0034864799
-
Proteasome inhibitors: From research tools to drug candidates
-
Kisselev, A.F. & Goldberg, A.L. (2001) Proteasome inhibitors: from research tools to drug candidates. Chem. Biol. 8, 739-758
-
(2001)
Chem. Biol.
, vol.8
, pp. 739-758
-
-
Kisselev, A.F.1
Goldberg, A.L.2
-
8
-
-
0032539702
-
Potent and selective inhibitors of the proteasome: Dipeptidyl boronic acids
-
Adams, J., Behnke, M., Chen, S., Cruickshank, A.A., Dick, L.R., Grenier, L., Klunder, J.M., Ma, Y.T., Plamondon, L. & Stein, R.L. (1998) Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids. Bioorg. Med. Chem. Lett. 8, 333-338
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 333-338
-
-
Adams, J.1
Behnke, M.2
Chen, S.3
Cruickshank, A.A.4
Dick, L.R.5
Grenier, L.6
Klunder, J.M.7
Ma, Y.T.8
Plamondon, L.9
Stein, R.L.10
-
9
-
-
0036240701
-
The proteasome: A novel target for cancer chemotherapy
-
Almond, J.B. & Cohen, G.M. (2002) The proteasome: a novel target for cancer chemotherapy. Leukemia 16, 433-443
-
(2002)
Leukemia
, vol.16
, pp. 433-443
-
-
Almond, J.B.1
Cohen, G.M.2
-
10
-
-
0032189685
-
Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor
-
Orlowski, R.Z., Eswara, J.R., Lafond-Walker, A., Grever, M.R., Orlowski, M. & Dang, C.V. (1998) Tumor growth inhibition induced in a murine model of human Burkitt's lymphoma by a proteasome inhibitor. Cancer Res. 58, 4342-4348
-
(1998)
Cancer Res.
, vol.58
, pp. 4342-4348
-
-
Orlowski, R.Z.1
Eswara, J.R.2
Lafond-Walker, A.3
Grever, M.R.4
Orlowski, M.5
Dang, C.V.6
-
11
-
-
0343091329
-
Ubiquitin-proteasome system and increased sensitivity of B-CLL lymphocytes to apoptotic death activation
-
Masdehors, P., Merle-Beral, H., Magdelenat, H. & Delic, J. (2000) Ubiquitin-proteasome system and increased sensitivity of B-CLL lymphocytes to apoptotic death activation. Leuk. Lymphoma 38, 499-504
-
(2000)
Leuk. Lymphoma
, vol.38
, pp. 499-504
-
-
Masdehors, P.1
Merle-Beral, H.2
Magdelenat, H.3
Delic, J.4
-
12
-
-
0035328584
-
Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: Implications for systemic nuclear factor-κB inhibition
-
Cusack, Jr, J.C., Liu, R., Houston, M., Abendroth, K., Elliott, P.J., Adams, J. & Baldwin, Jr, A.S. (2001) Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-κB inhibition. Cancer Res. 61, 3535-3540
-
(2001)
Cancer Res.
, vol.61
, pp. 3535-3540
-
-
Cusack Jr., J.C.1
Liu, R.2
Houston, M.3
Abendroth, K.4
Elliott, P.J.5
Adams, J.6
Baldwin Jr., A.S.7
-
13
-
-
0033152760
-
Proteasome inhibitors: A novel class of potent and effective antitumor agents
-
Adams, J., Palombella, V.J., Sausville, E.A., Johnson, J., Destree, A., Lazarus, D.D., Maas, J., Pien, C.S., Prakash, S. & Elliott, P.J. (1999) Proteasome inhibitors: a novel class of potent and effective antitumor agents. Cancer Res. 59, 2615-2622
-
(1999)
Cancer Res.
, vol.59
, pp. 2615-2622
-
-
Adams, J.1
Palombella, V.J.2
Sausville, E.A.3
Johnson, J.4
Destree, A.5
Lazarus, D.D.6
Maas, J.7
Pien, C.S.8
Prakash, S.9
Elliott, P.J.10
-
14
-
-
0035300479
-
The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
-
Hideshima, T., Richardson, P., Chauhan, D., Palombella, V.J., Elliott, P.J., Adams, J. & Anderson, K.C. (2001) The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells. Cancer Res. 61, 3071-3076
-
(2001)
Cancer Res.
, vol.61
, pp. 3071-3076
-
-
Hideshima, T.1
Richardson, P.2
Chauhan, D.3
Palombella, V.J.4
Elliott, P.J.5
Adams, J.6
Anderson, K.C.7
-
15
-
-
0242496212
-
Molecular sequelae of proteasome inhibition in human multiple myeloma cells
-
Mitsiades, N., Mitsiades, C.S., Poulaki, V., Chauhan, D., Fanourakis, G., Gu, X., Bailey, C., Joseph, M., Libermann, T.A., Treon, S.P. et al. (2002) Molecular sequelae of proteasome inhibition in human multiple myeloma cells. Proc. Natl. Acad. Sci. U.S.A. 99, 14374-14379
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 14374-14379
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Fanourakis, G.5
Gu, X.6
Bailey, C.7
Joseph, M.8
Libermann, T.A.9
Treon, S.P.10
-
16
-
-
0037097595
-
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: Therapeutic implications
-
Mitsiades, N., Mitsiades, C.S., Poulaki, V., Chauhan, D., Richardson, P.G., Hideshima, T., Munshi, N.C., Treon, S.P. & Anderson, K.C. (2002) Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications. Blood 99, 4525-4530
-
(2002)
Blood
, vol.99
, pp. 4525-4530
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Chauhan, D.4
Richardson, P.G.5
Hideshima, T.6
Munshi, N.C.7
Treon, S.P.8
Anderson, K.C.9
-
17
-
-
0037443551
-
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
-
Mitsiades, N., Mitsiades, C.S., Richardson, P.G., Poulaki, V., Tai, Y.T., Chauhan, D., Fanourakis, G., Gu, X., Bailey, C., Joseph, M. et al. (2003) The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 101, 2377-2380
-
(2003)
Blood
, vol.101
, pp. 2377-2380
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
Poulaki, V.4
Tai, Y.T.5
Chauhan, D.6
Fanourakis, G.7
Gu, X.8
Bailey, C.9
Joseph, M.10
-
18
-
-
0038206722
-
Inhibition of constitutive NF-kB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis
-
Pham, L.V., Tamayo, A.T., Yoshimura, L.C., Lo, P. & Ford, R.J. (2003) Inhibition of constitutive NF-kB activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis. J. Immunol. 171, 88-95
-
(2003)
J. Immunol.
, vol.171
, pp. 88-95
-
-
Pham, L.V.1
Tamayo, A.T.2
Yoshimura, L.C.3
Lo, P.4
Ford, R.J.5
-
19
-
-
0032885416
-
The proteasome inhibitor PS-341 in cancer therapy
-
Teicher, B.A., Ara, G., Herbst, R., Palombella, V.J. & Adams, J. (1999) The proteasome inhibitor PS-341 in cancer therapy. Clin. Cancer Res. 5, 2638-2645
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 2638-2645
-
-
Teicher, B.A.1
Ara, G.2
Herbst, R.3
Palombella, V.J.4
Adams, J.5
-
20
-
-
0033817518
-
Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341
-
Frankel, A., Man, S., Elliott, P., Adams, J. & Kerbel, R.S. (2000) Lack of multicellular drug resistance observed in human ovarian and prostate carcinoma treated with the proteasome inhibitor PS-341. Clin. Cancer Res. 6, 3719-3728
-
(2000)
Clin. Cancer Res.
, vol.6
, pp. 3719-3728
-
-
Frankel, A.1
Man, S.2
Elliott, P.3
Adams, J.4
Kerbel, R.S.5
-
21
-
-
0034981649
-
26 S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer
-
Shah, S.A., Potter, M.W., McDade, T.P., Ricciardi, R., Perugini, R.A., Elliott, P.J., Adams, J. & Callery, M.P. (2001) 26 S proteasome inhibition induces apoptosis and limits growth of human pancreatic cancer. J. Cell. Biochem. 82, 110-122
-
(2001)
J. Cell. Biochem.
, vol.82
, pp. 110-122
-
-
Shah, S.A.1
Potter, M.W.2
McDade, T.P.3
Ricciardi, R.4
Perugini, R.A.5
Elliott, P.J.6
Adams, J.7
Callery, M.P.8
-
22
-
-
0035072563
-
p53-dependent apoptosis induced by proteasome inhibition in mammary epithelial cells
-
MacLaren, A.P., Chapman, R.S., Wyllie, A.H. & Watson, C.J. (2001) p53-dependent apoptosis induced by proteasome inhibition in mammary epithelial cells. Cell Death Differ. 8, 210-218
-
(2001)
Cell Death Differ.
, vol.8
, pp. 210-218
-
-
MacLaren, A.P.1
Chapman, R.S.2
Wyllie, A.H.3
Watson, C.J.4
-
23
-
-
0037059012
-
Preferential induction of apoptosis for primary human leukemic stem cells
-
Guzman, M.L., Swiderski, C.F., Howard, D.S., Grimes, B.A., Rossi, R.M., Szilvassy, S.J. & Jordan, C.T. (2002) Preferential induction of apoptosis for primary human leukemic stem cells. Proc. Natl. Acad. Sci. U.S.A. 99, 16220-16225
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 16220-16225
-
-
Guzman, M.L.1
Swiderski, C.F.2
Howard, D.S.3
Grimes, B.A.4
Rossi, R.M.5
Szilvassy, S.J.6
Jordan, C.T.7
-
24
-
-
0043193876
-
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells
-
Lee, A.H., Iwakoshi, N.N., Anderson, K.C. & Glimcher, L.H. (2003) Proteasome inhibitors disrupt the unfolded protein response in myeloma cells. Proc. Natl. Acad. Sci. U.S.A. 100, 9946-9951
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 9946-9951
-
-
Lee, A.H.1
Iwakoshi, N.N.2
Anderson, K.C.3
Glimcher, L.H.4
-
25
-
-
0037158513
-
Activation of NF-kB and upregulation of intracellular anti-apoptotic proteins via the IGF-I/Akt signaling in human multiple myeloma cells: Therapeutic implications
-
Mitsiades, C.S., Mitsiades, N., Poulaki, V., Schlossman, R., Akiyama, M., Chauhan, D., Hideshima, T., Treon, S.P., Munshi, N.C., Richardson, P.G. & Anderson, K.C. (2002) Activation of NF-kB and upregulation of intracellular anti-apoptotic proteins via the IGF-I/Akt signaling in human multiple myeloma cells: therapeutic implications. Oncogens 21, 5673-5683
-
(2002)
Oncogens
, vol.21
, pp. 5673-5683
-
-
Mitsiades, C.S.1
Mitsiades, N.2
Poulaki, V.3
Schlossman, R.4
Akiyama, M.5
Chauhan, D.6
Hideshima, T.7
Treon, S.P.8
Munshi, N.C.9
Richardson, P.G.10
Anderson, K.C.11
-
26
-
-
0037085796
-
Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells
-
Mitsiades, N., Mitsiades, C.S., Poulaki, V., Anderson, K.C. & Treon, S.P. (2002) Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells. Blood 99, 2162-2171
-
(2002)
Blood
, vol.99
, pp. 2162-2171
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Anderson, K.C.4
Treon, S.P.5
-
27
-
-
0034895563
-
Concepts in the use of TRAIL/Apo2L: An emerging biotherapy for myeloma and other neoplasias
-
Mitsiades, N., Mitsiades, C.S., Poulaki, V., Anderson, K.C. & Treon, S.P. (2001) Concepts in the use of TRAIL/Apo2L: an emerging biotherapy for myeloma and other neoplasias. Expert Opin. Invest. Drugs 10, 1521-1530
-
(2001)
Expert Opin. Invest. Drugs
, vol.10
, pp. 1521-1530
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
Anderson, K.C.4
Treon, S.P.5
-
28
-
-
0030041147
-
Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kB
-
Chauhan, D., Uchiyama, H., Akbarali, Y., Urashima, M., Yamamoto, K., Libermann, T.A. & Anderson, K.C. (1996) Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-kB. Blood 87, 1104-1112
-
(1996)
Blood
, vol.87
, pp. 1104-1112
-
-
Chauhan, D.1
Uchiyama, H.2
Akbarali, Y.3
Urashima, M.4
Yamamoto, K.5
Libermann, T.A.6
Anderson, K.C.7
-
29
-
-
0026793868
-
Role of interleukin 6 in the growth of myeloma-derived cell lines
-
Barut, B.A., Zon, L.I., Cochran, M.K., Paul, S.R., Chauhan, D., Mohrbacher, A., Fingeroth, J. & Anderson, K.C. (1992) Role of interleukin 6 in the growth of myeloma-derived cell lines. Leuk. Res. 16, 951-959
-
(1992)
Leuk. Res.
, vol.16
, pp. 951-959
-
-
Barut, B.A.1
Zon, L.I.2
Cochran, M.K.3
Paul, S.R.4
Chauhan, D.5
Mohrbacher, A.6
Fingeroth, J.7
Anderson, K.C.8
-
30
-
-
0031034160
-
Activation of the cell death program by inhibition of proteasome function
-
Drexler, H.C. (1997) Activation of the cell death program by inhibition of proteasome function. Proc. Natl. Acad. Sci. U.S.A. 94, 855-060
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 855-1060
-
-
Drexler, H.C.1
-
31
-
-
0033965742
-
Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells
-
Drexler, H.C., Risau, W. & Konerding, M.A. (2000) Inhibition of proteasome function induces programmed cell death in proliferating endothelial cells. FASEB J. 14, 65-77
-
(2000)
FASEB J.
, vol.14
, pp. 65-77
-
-
Drexler, H.C.1
Risau, W.2
Konerding, M.A.3
-
32
-
-
0033059459
-
Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin
-
Masdehors, P., Omura, S., Merle-Beral, H., Mentz, F., Cosset, J.M., Dumont, J., Magdelenat, H. & Delic, J. (1999) Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin. Br. J. Haematol. 105, 752-757
-
(1999)
Br. J. Haematol.
, vol.105
, pp. 752-757
-
-
Masdehors, P.1
Omura, S.2
Merle-Beral, H.3
Mentz, F.4
Cosset, J.M.5
Dumont, J.6
Magdelenat, H.7
Delic, J.8
-
33
-
-
2342613652
-
The proteasome: A suitable antineoplastic target
-
Adams, J. (2004) The proteasome: a suitable antineoplastic target. Nat. Rev. Cancer 4, 349-360
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 349-360
-
-
Adams, J.1
-
34
-
-
0037111832
-
Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
-
Orlowski, R.Z., Stinchcombe, T.E., Mitchell, B.S., Shea, T.C., Baldwin, A.S., Stahl, S., Adams, J., Esseltine, D.L., Elliott, P.J., Pien, C.S. et al. (2002) Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies. J. Clin. Oncol. 20, 4420-4427
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 4420-4427
-
-
Orlowski, R.Z.1
Stinchcombe, T.E.2
Mitchell, B.S.3
Shea, T.C.4
Baldwin, A.S.5
Stahl, S.6
Adams, J.7
Esseltine, D.L.8
Elliott, P.J.9
Pien, C.S.10
-
35
-
-
2542481724
-
Phase I study of bortezomib in refractory or relapsed acute leukemias
-
Cortes, J., Thomas, D., Koller, C., Giles, F., Estey, E., Faderl, S., Garcia-Manero, G., McConkey, D., Patel, G., Guerciolini, R. et al. (2004) Phase I study of bortezomib in refractory or relapsed acute leukemias. Clin. Cancer Res. 10, 3371-3376
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 3371-3376
-
-
Cortes, J.1
Thomas, D.2
Koller, C.3
Giles, F.4
Estey, E.5
Faderl, S.6
Garcia-Manero, G.7
McConkey, D.8
Patel, G.9
Guerciolini, R.10
-
36
-
-
0036023407
-
A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies
-
Aghajanian, C., Soignet, S., Dizon, D.S., Pien, C.S., Adams, J., Elliott, P.J., Sabbatini, P., Miller, V., Hensley, M.L., Pezzulli, S. et al. (2002) A phase I trial of the novel proteasome inhibitor PS341 in advanced solid tumor malignancies. Clin. Cancer Res. 8, 2505-2511
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 2505-2511
-
-
Aghajanian, C.1
Soignet, S.2
Dizon, D.S.3
Pien, C.S.4
Adams, J.5
Elliott, P.J.6
Sabbatini, P.7
Miller, V.8
Hensley, M.L.9
Pezzulli, S.10
-
37
-
-
2942692143
-
Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer
-
Papandreou, C.N., Daliani, D.D., Nix, D., Yang, H., Madden, T., Wang, X., Pien, C.S., Millikan, R.E., Tu, S.M., Pagliaro, L. et al. (2004) Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J. Clin. Oncol. 22, 2108-2121
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 2108-2121
-
-
Papandreou, C.N.1
Daliani, D.D.2
Nix, D.3
Yang, H.4
Madden, T.5
Wang, X.6
Pien, C.S.7
Millikan, R.E.8
Tu, S.M.9
Pagliaro, L.10
-
38
-
-
0036181371
-
Development of the proteasome inhibitor PS-341
-
Adams, J. (2002) Development of the proteasome inhibitor PS-341. Oncologist 7, 9-16
-
(2002)
Oncologist
, vol.7
, pp. 9-16
-
-
Adams, J.1
-
39
-
-
0037973279
-
A phase 2 study of bortezomib in relapsed, refractory myeloma
-
Richardson, P.G., Barlogie, B., Berenson, J., Singhal, S., Jagannath, S., Irwin, D., Rajkumar, S.V., Srkalovic, G., Alsina, M., Alexanian, R. et al. (2003) A phase 2 study of bortezomib in relapsed, refractory myeloma. N. Engl. J. Med. 348, 2609-2617
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 2609-2617
-
-
Richardson, P.G.1
Barlogie, B.2
Berenson, J.3
Singhal, S.4
Jagannath, S.5
Irwin, D.6
Rajkumar, S.V.7
Srkalovic, G.8
Alsina, M.9
Alexanian, R.10
-
40
-
-
5644250621
-
A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma
-
Jagannath, S., Barlogie, B., Berenson, J., Siegel, D., Irwin, D., Richardson, P.G., Niesvizky, R., Alexanian, R., Limentani, S.A., Alsina, M. et al. (2004) A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma. Br. J. Haematol. 127, 165-172
-
(2004)
Br. J. Haematol.
, vol.127
, pp. 165-172
-
-
Jagannath, S.1
Barlogie, B.2
Berenson, J.3
Siegel, D.4
Irwin, D.5
Richardson, P.G.6
Niesvizky, R.7
Alexanian, R.8
Limentani, S.A.9
Alsina, M.10
-
41
-
-
20444433230
-
Bortezomib vs. dexamethasone in relapsed multiple myeloma: A phase 3 randomized study
-
in the press
-
Richardson, P.G., Sonneveld, P., Schuster, M.W., Irwin, D., Stadtmauer, E.A., Facon, T., Dalton, W.S., Harousseau, J.L., San Miguel, J.F. & Anderson, K.C. (2005) Bortezomib vs. dexamethasone in relapsed multiple myeloma: a phase 3 randomized study. N. Engl. J. Med. in the press
-
(2005)
N. Engl. J. Med.
-
-
Richardson, P.G.1
Sonneveld, P.2
Schuster, M.W.3
Irwin, D.4
Stadtmauer, E.A.5
Facon, T.6
Dalton, W.S.7
Harousseau, J.L.8
San Miguel, J.F.9
Anderson, K.C.10
-
42
-
-
21344452026
-
The proteasome inhibitor bortezomib (PS-341) is active against Waldenstrom's macroglobulinemia (WM)
-
Abstract no. 631
-
Mitsiades, C.S., Mitsiades, N., McMullan, C.J., Poulaki, V., Shringarpure, R., Hideshima, T., Chauhan, D., Treon, S.P., Richardson, P.G., Munshi et al. (2003) The proteasome inhibitor bortezomib (PS-341) is active against Waldenstrom's macroglobulinemia (WM). Blood 102 (suppl), Abstract no. 631
-
(2003)
Blood
, vol.102
, Issue.SUPPL.
-
-
Mitsiades, C.S.1
Mitsiades, N.2
McMullan, C.J.3
Poulaki, V.4
Shringarpure, R.5
Hideshima, T.6
Chauhan, D.7
Treon, S.P.8
Richardson, P.G.9
Munshi10
-
43
-
-
20044396543
-
Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma
-
Goy, A., Younes, A., McLaughlin, P., Pro, B., Romaguera, J.E., Hagemeister, F., Fayad, L., Dang, N.H., Samaniego, F., Wang, M. et al. (2005) Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma. J. Clin. Oncol. 23, 667-675
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 667-675
-
-
Goy, A.1
Younes, A.2
McLaughlin, P.3
Pro, B.4
Romaguera, J.E.5
Hagemeister, F.6
Fayad, L.7
Dang, N.H.8
Samaniego, F.9
Wang, M.10
-
44
-
-
20044376092
-
Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma
-
O'Connor, O.A., Wright, J., Moskowitz, C., Muzzy, J., MacGregor-Cortelli, B., Stubblefield, M., Straus, D., Portlock, C., Hamlin, P., Choi, E. et al. (2005) Phase II clinical experience with the novel proteasome inhibitor bortezomib in patients with indolent non-Hodgkin's lymphoma and mantle cell lymphoma. J. Clin. Oncol. 23, 676-684
-
(2005)
J. Clin. Oncol.
, vol.23
, pp. 676-684
-
-
O'Connor, O.A.1
Wright, J.2
Moskowitz, C.3
Muzzy, J.4
MacGregor-Cortelli, B.5
Stubblefield, M.6
Straus, D.7
Portlock, C.8
Hamlin, P.9
Choi, E.10
-
45
-
-
4644304196
-
Phase II trial of bortezomib for patients with advanced renal cell carcinoma
-
Kondagunta, G.V., Drucker, B., Schwartz, L., Bacik, J., Marion, S., Russo, P., Mazumdar, M. & Motzer, R.J. (2004) Phase II trial of bortezomib for patients with advanced renal cell carcinoma. J. Clin. Oncol. 22, 3720-3725
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 3720-3725
-
-
Kondagunta, G.V.1
Drucker, B.2
Schwartz, L.3
Bacik, J.4
Marion, S.5
Russo, P.6
Mazumdar, M.7
Motzer, R.J.8
-
46
-
-
2442510143
-
Phase II trial of PS-341 in patients with renal cell cancer: A University of Chicago phase II consortium study
-
Davis, N.B., Taber, D.A., Ansari, R.H., Ryan, C.W., George, C., Vokes, E.E., Vogelzang, N.J. & Stadler, W.M. (2004) Phase II trial of PS-341 in patients with renal cell cancer: a University of Chicago phase II consortium study. J. Clin. Oncol. 22, 115-119
-
(2004)
J. Clin. Oncol.
, vol.22
, pp. 115-119
-
-
Davis, N.B.1
Taber, D.A.2
Ansari, R.H.3
Ryan, C.W.4
George, C.5
Vokes, E.E.6
Vogelzang, N.J.7
Stadler, W.M.8
-
47
-
-
18844421493
-
Bortezomib ± irinotecan in relapsed/refractory colorectal cancer (CRC): Interim analysis results from a phase 2b study
-
Abstract
-
Dragovich, T., Lenz, H.J., Rocha Lima, C.M.S., Kozuch, P., Hochster, H., O'Neil, B., Atiq, O., Pipas, J.M., Kashala, O. & Schenkein, D.P. (2004) Bortezomib ± irinotecan in relapsed/refractory colorectal cancer (CRC): interim analysis results from a phase 2b study. J. Clin. Oncol. 22 (Suppl.), 267s (Abstract)
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.SUPPL.
-
-
Dragovich, T.1
Lenz, H.J.2
Rocha Lima, C.M.S.3
Kozuch, P.4
Hochster, H.5
O'Neil, B.6
Atiq, O.7
Pipas, J.M.8
Kashala, O.9
Schenkein, D.P.10
-
48
-
-
10044292218
-
Phase (ph) 2 study of bortezomib ± docetaxel inpreviously treated patients (pts) with advanced non-small cell lung cancer (NSCLC). Preliminary results
-
Abstract
-
Fanucchi, M.P., Belt, R.J., Fossella, F.V., Natale, B., Robert, F., Fidias, P., Kelly, K., Kashala, O., Schenkein, D.P. & Schiller, J.H. (2004) Phase (ph) 2 study of bortezomib ± docetaxel inpreviously treated patients (pts) with advanced non-small cell lung cancer (NSCLC). Preliminary results. J. Clin. Oncol. 22 (Suppl.), 643s (Abstract)
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.SUPPL.
-
-
Fanucchi, M.P.1
Belt, R.J.2
Fossella, F.V.3
Natale, B.4
Robert, F.5
Fidias, P.6
Kelly, K.7
Kashala, O.8
Schenkein, D.P.9
Schiller, J.H.10
-
49
-
-
12744268798
-
Phase I/II trial of VELCADE® plus docetaxel in patients with advanced androgen-independent prostate cancer
-
Abstract
-
Dreicer, R., Roth, B., Petrylak, D., Agus, D., Meyers, M., Esseltine, D., Rodriquez, D., Oppedisano, P., Wang, K. & Boral, A.(2004) Phase I/II trial of VELCADE® plus docetaxel in patients with advanced androgen-independent prostate cancer. J. Clin. Oncol. 22 (Suppl.), 420s (Abstract)
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.SUPPL.
-
-
Dreicer, R.1
Roth, B.2
Petrylak, D.3
Agus, D.4
Meyers, M.5
Esseltine, D.6
Rodriquez, D.7
Oppedisano, P.8
Wang, K.9
Boral, A.10
-
50
-
-
4644248931
-
Phase II study of the proteasome inhibitor bortezomib (PS-341) in patients with metastatic neuroendocrine tumors
-
Shah, M.H., Young, D., Kindler, H.L., Webb, I., Kleiber, B., Wright, J. & Grever, M. (2004) Phase II study of the proteasome inhibitor bortezomib (PS-341) in patients with metastatic neuroendocrine tumors. Clin. Cancer Res. 10, 6111-6118
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 6111-6118
-
-
Shah, M.H.1
Young, D.2
Kindler, H.L.3
Webb, I.4
Kleiber, B.5
Wright, J.6
Grever, M.7
-
51
-
-
17644379243
-
Phase II/pharmacodynamic trial of PS-341 (bortezomib, VELCADE®) in advanced non-small cell lung cancer
-
Abstract
-
Stevenson, J., Nho, C.W., Johnson, S.W. et al. (2004) Phase II/pharmacodynamic trial of PS-341 (bortezomib, VELCADE®) in advanced non-small cell lung cancer. J. Clin. Oncol. 22 (Suppl.), 652s (Abstract)
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.SUPPL.
-
-
Stevenson, J.1
Nho, C.W.2
Johnson, S.W.3
-
52
-
-
10344236596
-
Phase I/II trial of bortezomib (VELCADE®) in patients with unresectable hepatocellular carcinoma
-
Abstract
-
Hegewisch-Becker, S., Sterneck, M., Schubert, U., Rogiers, X., Guerciolini, R., Pierce, J.E. & Hossfeld, D.K. (2004) Phase I/II trial of bortezomib (VELCADE®) in patients with unresectable hepatocellular carcinoma. J. Clin. Oncol. 22 (Suppl.), 335s (Abstract)
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.SUPPL.
-
-
Hegewisch-Becker, S.1
Sterneck, M.2
Schubert, U.3
Rogiers, X.4
Guerciolini, R.5
Pierce, J.E.6
Hossfeld, D.K.7
|