Site-directed mutagenesis of the N-linked glycosylation site in platelet-derived growth factor B-chain results in diminished intracellular retention

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1298, Issue 2, 1996, Pages 250-260

  Kaetzel Jr , David M ^a   Morgan III, Dewey ^b   Reid IV, James D ^b   Fenstermaker, Robert A ^b  

^a UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Mitogenesis; N Glycosylation; Platelet derived growth factor; Pulse chase analysis; Receptor binding; Secretion

Indexed keywords

PLATELET DERIVED GROWTH FACTOR B;

ANIMAL CELL; ARTICLE; CELL SURFACE; CHO CELL; CONTROLLED STUDY; GENE EXPRESSION; GLYCOSYLATION; IMMUNOPRECIPITATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROCESSING; PROTEIN TRANSPORT; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ASPARAGINE; BINDING SITES; BIOLOGICAL TRANSPORT; CHO CELLS; CRICETINAE; GLYCOSYLATION; HUMANS; INFANT, NEWBORN; MUTAGENESIS, SITE-DIRECTED; PLATELET-DERIVED GROWTH FACTOR; PROTEIN PRECURSORS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; RECOMBINANT PROTEINS;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0030571591     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(96)00136-7     Document Type: Article

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