메뉴 건너뛰기




Volumn 25, Issue 42, 2005, Pages 9704-9720

Proximal persistent Na+ channels drive spike afterdepolarizations and associated bursting in adult CA1 pyramidal cells

Author keywords

Afterdepolarization; Burst; CA1 pyramidal cell; Hippocampus; M current; Persistent sodium current; Phenytoin; PKC; Riluzole

Indexed keywords

SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT;

EID: 27144464110     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1621-05.2005     Document Type: Article
Times cited : (166)

References (80)
  • 1
    • 0033166919 scopus 로고    scopus 로고
    • Protein kinase C mediates muscarinic block of intrinsic bursting in rat hippocampal neurons
    • Alroy G, Su H, Yaari Y (1999) Protein kinase C mediates muscarinic block of intrinsic bursting in rat hippocampal neurons. J Physiol (Lond) 518:71-79.
    • (1999) J Physiol (Lond) , vol.518 , pp. 71-79
    • Alroy, G.1    Su, H.2    Yaari, Y.3
  • 2
    • 0033567139 scopus 로고    scopus 로고
    • Somatic amplification of distally generated subthreshold EPSPs in rat hippocampal pyramidal neurones
    • Andreasen M, Lambert JD (1999) Somatic amplification of distally generated subthreshold EPSPs in rat hippocampal pyramidal neurones. J Physiol (Lond) 519:85-100.
    • (1999) J Physiol (Lond) , vol.519 , pp. 85-100
    • Andreasen, M.1    Lambert, J.D.2
  • 4
    • 0029963240 scopus 로고    scopus 로고
    • Ionic basis of spike afterdepolarization and burst generation in adult rat hippocampal CA1 pyramidal cells
    • Azouz R, Jensen MS, Yaari Y (1996) Ionic basis of spike afterdepolarization and burst generation in adult rat hippocampal CA1 pyramidal cells. J Physiol (Lond) 492:211-223.
    • (1996) J Physiol (Lond) , vol.492 , pp. 211-223
    • Azouz, R.1    Jensen, M.S.2    Yaari, Y.3
  • 5
    • 0037444623 scopus 로고    scopus 로고
    • Functional specialization of the axon initial segment by isoform-specific sodium channel targeting
    • Boiko T, Van Wart A, Caldwell JH, Levinson SR, Trimmer JS, Matthews G (2003) Functional specialization of the axon initial segment by isoform-specific sodium channel targeting. J Neurosci 23:2306-2313.
    • (2003) J Neurosci , vol.23 , pp. 2306-2313
    • Boiko, T.1    Van Wart, A.2    Caldwell, J.H.3    Levinson, S.R.4    Trimmer, J.S.5    Matthews, G.6
  • 6
    • 0033818515 scopus 로고    scopus 로고
    • Modulation and genetic identification of the M channel
    • Brown BS, Yu SP (2000) Modulation and genetic identification of the M channel. Prog Biophys Mol Biol 73:135-166.
    • (2000) Prog Biophys Mol Biol , vol.73 , pp. 135-166
    • Brown, B.S.1    Yu, S.P.2
  • 7
    • 0034235752 scopus 로고    scopus 로고
    • Ionic mechanisms underlying repetitive high-frequency burst firing in supragranular cortical neurons
    • Brumberg JC, Nowak LG, McCormick DA (2000) Ionic mechanisms underlying repetitive high-frequency burst firing in supragranular cortical neurons. J Neurosci 20:4829-4843.
    • (2000) J Neurosci , vol.20 , pp. 4829-4843
    • Brumberg, J.C.1    Nowak, L.G.2    McCormick, D.A.3
  • 9
    • 0029953566 scopus 로고    scopus 로고
    • Muscarinic modulation of sodium current by activation of protein kinase C in rat hippocampal neurons
    • Cantrell AR, Ma JY, Scheuer T, Catterall WA (1996) Muscarinic modulation of sodium current by activation of protein kinase C in rat hippocampal neurons. Neuron 16:1019-1026.
    • (1996) Neuron , vol.16 , pp. 1019-1026
    • Cantrell, A.R.1    Ma, J.Y.2    Scheuer, T.3    Catterall, W.A.4
  • 10
    • 0037008251 scopus 로고    scopus 로고
    • Modulation of recombinant and native neuronal SK channels by the neuroprotective drug riluzole
    • Cao YJ, Dreixler JC, Couey JJ, Houamed KM (2002) Modulation of recombinant and native neuronal SK channels by the neuroprotective drug riluzole. Eur J Pharmacol 449:47-54.
    • (2002) Eur J Pharmacol , vol.449 , pp. 47-54
    • Cao, Y.J.1    Dreixler, J.C.2    Couey, J.J.3    Houamed, K.M.4
  • 11
    • 0037104778 scopus 로고    scopus 로고
    • Serotonin receptor activation inhibits sodium current and dendritic excitability in prefrontal cortex via a protein kinase C-dependent mechanism
    • Carr DB, Cooper DC, Ulrich SL, Spruston N, Surmeier DJ (2002) Serotonin receptor activation inhibits sodium current and dendritic excitability in prefrontal cortex via a protein kinase C-dependent mechanism. J Neurosci 22:6846-6855.
    • (2002) J Neurosci , vol.22 , pp. 6846-6855
    • Carr, D.B.1    Cooper, D.C.2    Ulrich, S.L.3    Spruston, N.4    Surmeier, D.J.5
  • 12
    • 0020326790 scopus 로고
    • Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters
    • Castagna M, Takai Y, Kaibuchi K, Sano K, Kikkawa U, Nishizuka Y (1982) Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. J Biol Chem 257:7847-7851.
    • (1982) J Biol Chem , vol.257 , pp. 7847-7851
    • Castagna, M.1    Takai, Y.2    Kaibuchi, K.3    Sano, K.4    Kikkawa, U.5    Nishizuka, Y.6
  • 13
    • 0029051044 scopus 로고
    • + current of mammalian CNS neurones
    • + current of mammalian CNS neurones. NeuroReport 6:1778-1780.
    • (1995) NeuroReport , vol.6 , pp. 1778-1780
    • Chao, T.I.1    Alzheimer, C.2
  • 14
    • 23844526134 scopus 로고    scopus 로고
    • 2+-dependent bursting triggered by spike backpropagation into apical dendrites in developing rat CA1 neurons
    • 2+-dependent bursting triggered by spike backpropagation into apical dendrites in developing rat CA1 neurons. J Physiol (Lond) 567:79-93.
    • (2005) J Physiol (Lond) , vol.567 , pp. 79-93
    • Chen, S.1    Yue, C.2    Yaari, Y.3
  • 15
    • 0029861108 scopus 로고    scopus 로고
    • + channel densities in the soma and axon initial segment of subicular pyramidal neurons
    • + channel densities in the soma and axon initial segment of subicular pyramidal neurons. J Neurosci 16:6676-6686.
    • (1996) J Neurosci , vol.16 , pp. 6676-6686
    • Colbert, C.M.1    Johnston, D.2
  • 16
    • 0031953135 scopus 로고    scopus 로고
    • + current in hippocampal CA1 pyramidal neurons
    • + current in hippocampal CA1 pyramidal neurons. J Neurophysiol 79:491-495.
    • (1998) J Neurophysiol , vol.79 , pp. 491-495
    • Colbert, C.M.1    Johnston, D.2
  • 17
    • 3042641308 scopus 로고    scopus 로고
    • Protein-kinase C-dependent phosphorylation inhibits the effect of the antiepileptic drug topiramate on the persistent fraction of sodium currents
    • Curia G, Aracri P, Sancini G, Mantegazza M, Avanzini G, Franceschetti S (2004) Protein-kinase C-dependent phosphorylation inhibits the effect of the antiepileptic drug topiramate on the persistent fraction of sodium currents. Neuroscience 127:63-68.
    • (2004) Neuroscience , vol.127 , pp. 63-68
    • Curia, G.1    Aracri, P.2    Sancini, G.3    Mantegazza, M.4    Avanzini, G.5    Franceschetti, S.6
  • 19
    • 0025427677 scopus 로고
    • Protein kinase C-dependent and -independent effects of phorbol esters on hippocampal calcium channel current
    • Doerner D, Abdel-Latif M, Rogers TB, Alger BE (1990) Protein kinase C-dependent and -independent effects of phorbol esters on hippocampal calcium channel current. J Neurosci 10:1699-1706.
    • (1990) J Neurosci , vol.10 , pp. 1699-1706
    • Doerner, D.1    Abdel-Latif, M.2    Rogers, T.B.3    Alger, B.E.4
  • 22
    • 0025328168 scopus 로고
    • A voltage-dependent persistent sodium current in mammalian hippocampal neurons
    • French CR, Sah P, Buckett KJ, Gage PW (1990) A voltage-dependent persistent sodium current in mammalian hippocampal neurons. J Gen Physiol 95:1139-1157.
    • (1990) J Gen Physiol , vol.95 , pp. 1139-1157
    • French, C.R.1    Sah, P.2    Buckett, K.J.3    Gage, P.W.4
  • 23
    • 0016835254 scopus 로고
    • Two types of depolarizing after-potentials in hippocampal pyramidal cells of rabbits
    • Fujita Y (1975) Two types of depolarizing after-potentials in hippocampal pyramidal cells of rabbits. Brain Res 94:435-446.
    • (1975) Brain Res , vol.94 , pp. 435-446
    • Fujita, Y.1
  • 24
    • 0030938142 scopus 로고    scopus 로고
    • 2+ channels in apical dendrites of rat CA1 pyramidal neurons
    • 2+ channels in apical dendrites of rat CA1 pyramidal neurons. J Neurophysiol 77:1639-1643.
    • (1997) J Neurophysiol , vol.77 , pp. 1639-1643
    • Gillessen, T.1    Alzheimer, C.2
  • 25
    • 0033044832 scopus 로고    scopus 로고
    • Diversity of mammalian voltage-gated sodium channels
    • Goldin AL (1999) Diversity of mammalian voltage-gated sodium channels. Ann NY Acad Sci 868:38-50.
    • (1999) Ann NY Acad Sci , vol.868 , pp. 38-50
    • Goldin, A.L.1
  • 26
    • 0032215718 scopus 로고    scopus 로고
    • Dendritic sodium spikes are variable triggers of axonal action potentials in hippocampal CA1 pyramidal neurons
    • Golding NL, Spruston N (1998) Dendritic sodium spikes are variable triggers of axonal action potentials in hippocampal CA1 pyramidal neurons. Neuron 21:1189-1200.
    • (1998) Neuron , vol.21 , pp. 1189-1200
    • Golding, N.L.1    Spruston, N.2
  • 27
    • 23744441740 scopus 로고    scopus 로고
    • Kv7/KCNQ/M and HCN/h, but not KCa2/SK channels, contribute to the somatic medium after-hyperpolarization and excitability control in CA1 hippocampal pyramidal cells
    • Gu N, Vervaeke K, Hu H, Storm JF (2005) Kv7/KCNQ/M and HCN/h, but not KCa2/SK channels, contribute to the somatic medium after-hyperpolarization and excitability control in CA1 hippocampal pyramidal cells. J Physiol (Lond) 566:689-715.
    • (2005) J Physiol (Lond) , vol.566 , pp. 689-715
    • Gu, N.1    Vervaeke, K.2    Hu, H.3    Storm, J.F.4
  • 28
    • 0030874515 scopus 로고    scopus 로고
    • Calcium-activated cation nonselective current contributes to the fast afterdepolarization in rat prefrontal cortex neurons
    • Haj-Dahmane S, Andrade R (1997) Calcium-activated cation nonselective current contributes to the fast afterdepolarization in rat prefrontal cortex neurons. J Neurophysiol 78:1983-1989.
    • (1997) J Neurophysiol , vol.78 , pp. 1983-1989
    • Haj-Dahmane, S.1    Andrade, R.2
  • 29
    • 0033360405 scopus 로고    scopus 로고
    • Selective localization of cardiac SCN5A sodium channels in limbic regions of rat brain
    • Hartmann HA, Colom LV, Sutherland ML, Noebels JL (1999) Selective localization of cardiac SCN5A sodium channels in limbic regions of rat brain. Nat Neurosci 2:593-595.
    • (1999) Nat Neurosci , vol.2 , pp. 593-595
    • Hartmann, H.A.1    Colom, L.V.2    Sutherland, M.L.3    Noebels, J.L.4
  • 30
    • 0025666303 scopus 로고
    • A calcium-dependent slow afterdepolarization recorded in rat dorsolateral septal nucleus neurons in vitro
    • Hasuo H, Phelan KD, Twery MJ, Gallagher JP (1990) A calcium-dependent slow afterdepolarization recorded in rat dorsolateral septal nucleus neurons in vitro. J Neurophysiol 64:1838-1846.
    • (1990) J Neurophysiol , vol.64 , pp. 1838-1846
    • Hasuo, H.1    Phelan, K.D.2    Twery, M.J.3    Gallagher, J.P.4
  • 31
    • 0017362119 scopus 로고
    • Extracellular free calcium and potassium during paroxysmal activity in the cerebral cortex of the cat
    • Heinemann U, Lux HD, Gutnick MJ (1977) Extracellular free calcium and potassium during paroxysmal activity in the cerebral cortex of the cat. Exp Brain Res 27:237-243.
    • (1977) Exp Brain Res , vol.27 , pp. 237-243
    • Heinemann, U.1    Lux, H.D.2    Gutnick, M.J.3
  • 32
    • 0016848139 scopus 로고
    • Negative surface charge near sodium channels of nerve: Divalent ions, monovalent ions, and pH
    • Hille B, Woodhull AM, Shapiro BI (1975) Negative surface charge near sodium channels of nerve: divalent ions, monovalent ions, and pH. Philos Trans R Soc Lond B Biol Sci 270:301-318.
    • (1975) Philos Trans R Soc Lond B Biol Sci , vol.270 , pp. 301-318
    • Hille, B.1    Woodhull, A.M.2    Shapiro, B.I.3
  • 33
    • 78651026696 scopus 로고
    • The effect of sodium ions on the electrical activity of the giant axon of the squid
    • Hodgkin AL, Katz B (1949) The effect of sodium ions on the electrical activity of the giant axon of the squid. J Physiol (Lond) 108:37-77.
    • (1949) J Physiol (Lond) , vol.108 , pp. 37-77
    • Hodgkin, A.L.1    Katz, B.2
  • 34
    • 0030855840 scopus 로고    scopus 로고
    • + channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons
    • + channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons. Nature 387:869-875.
    • (1997) Nature , vol.387 , pp. 869-875
    • Hoffman, D.A.1    Magee, J.C.2    Colbert, C.M.3    Johnston, D.4
  • 35
    • 0030886021 scopus 로고    scopus 로고
    • Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons
    • Huang CS, Song JH, Nagata K, Yeh JZ, Narahashi T (1997) Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons. J Pharmacol Exp Ther 282:1280-1290.
    • (1997) J Pharmacol Exp Ther , vol.282 , pp. 1280-1290
    • Huang, C.S.1    Song, J.H.2    Nagata, K.3    Yeh, J.Z.4    Narahashi, T.5
  • 36
    • 0035956420 scopus 로고    scopus 로고
    • Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments
    • Jenkins SM, Bennett V (2001) Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments. J Cell Biol 155:739-746.
    • (2001) J Cell Biol , vol.155 , pp. 739-746
    • Jenkins, S.M.1    Bennett, V.2
  • 37
    • 0028215297 scopus 로고
    • Variant firing patterns in rat hippocampal pyramidal cells modulated by extracellular potassium
    • Jensen MS, Azouz R, Yaari Y (1994) Variant firing patterns in rat hippocampal pyramidal cells modulated by extracellular potassium. J Neurophysiol 71:831-839.
    • (1994) J Neurophysiol , vol.71 , pp. 831-839
    • Jensen, M.S.1    Azouz, R.2    Yaari, Y.3
  • 38
    • 0029963239 scopus 로고    scopus 로고
    • Spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells
    • Jensen MS, Azouz R, Yaari Y (1996) Spike after-depolarization and burst generation in adult rat hippocampal CA1 pyramidal cells. J Physiol (Lond) 492:199-210.
    • (1996) J Physiol (Lond) , vol.492 , pp. 199-210
    • Jensen, M.S.1    Azouz, R.2    Yaari, Y.3
  • 39
    • 0035873173 scopus 로고    scopus 로고
    • Action potential bursting in subicular pyramidal neurons is driven by a calcium spike aftercurrent
    • Jung HY, Staff NP, Spruston N (2001) Action potential bursting in subicular pyramidal neurons is driven by a calcium spike aftercurrent. J Neurosci 21:3312-3321.
    • (2001) J Neurosci , vol.21 , pp. 3312-3321
    • Jung, H.Y.1    Staff, N.P.2    Spruston, N.3
  • 40
    • 0001192938 scopus 로고
    • Electrophysiology of hippocampal neurons. II. After-potentials and repetitive firing
    • Kandel ER, Spencer WA (1961) Electrophysiology of hippocampal neurons. II. After-potentials and repetitive firing. J Neurophysiol 24:243-259.
    • (1961) J Neurophysiol , vol.24 , pp. 243-259
    • Kandel, E.R.1    Spencer, W.A.2
  • 41
    • 0031763725 scopus 로고    scopus 로고
    • Kinetic and stochastic properties of a persistent sodium current in mature guinea pig cerebellar Purkinje cells
    • Kay AR, Sugimori M, Llinas R (1998) Kinetic and stochastic properties of a persistent sodium current in mature guinea pig cerebellar Purkinje cells. J Neurophysiol 80:1167-1179.
    • (1998) J Neurophysiol , vol.80 , pp. 1167-1179
    • Kay, A.R.1    Sugimori, M.2    Llinas, R.3
  • 44
    • 0032871142 scopus 로고    scopus 로고
    • Dendritic voltage-gated ion channels regulate the action potential firing mode of hippocampal CA1 pyramidal neurons
    • Magee JC, Carruth M (1999) Dendritic voltage-gated ion channels regulate the action potential firing mode of hippocampal CA1 pyramidal neurons. J Neurophysiol 82:1895-1901.
    • (1999) J Neurophysiol , vol.82 , pp. 1895-1901
    • Magee, J.C.1    Carruth, M.2
  • 45
    • 0022446151 scopus 로고
    • Potentiation of synaptic transmission in the hippocampus by phorbol esters
    • Malenka RC, Madison DV, Nicoll RA (1986) Potentiation of synaptic transmission in the hippocampus by phorbol esters. Nature 321:175-177.
    • (1986) Nature , vol.321 , pp. 175-177
    • Malenka, R.C.1    Madison, D.V.2    Nicoll, R.A.3
  • 46
    • 0032519602 scopus 로고    scopus 로고
    • Anemone toxin (ATX 11)-induced increase in persistent sodium current: Effects on the firing properties of rat neocortical pyramidal neurones
    • Mantegazza M, Franceschetti S, Avanzini G (1998) Anemone toxin (ATX 11)-induced increase in persistent sodium current: effects on the firing properties of rat neocortical pyramidal neurones. J Physiol (Lond) 507:105-116.
    • (1998) J Physiol (Lond) , vol.507 , pp. 105-116
    • Mantegazza, M.1    Franceschetti, S.2    Avanzini, G.3
  • 47
    • 0028314213 scopus 로고
    • M-current suppression by agonist and phorbol ester in bullfrog sympathetic neurons
    • Marrion NV (1994) M-current suppression by agonist and phorbol ester in bullfrog sympathetic neurons. Pflügers Arch 426:296-303.
    • (1994) Pflügers Arch , vol.426 , pp. 296-303
    • Marrion, N.V.1
  • 48
    • 0031036966 scopus 로고    scopus 로고
    • In vitro electrophysiology of rat subicular bursting neurons
    • Mattia D, Kawasaki H, Avoli M (1997) In vitro electrophysiology of rat subicular bursting neurons. Hippocampus 7:48-57.
    • (1997) Hippocampus , vol.7 , pp. 48-57
    • Mattia, D.1    Kawasaki, H.2    Avoli, M.3
  • 49
    • 0035297711 scopus 로고    scopus 로고
    • 5 dopamine receptor activation differentially modulates rapidly inactivating and persistent sodium currents in prefrontal cortex pyramidal neurons
    • 5 dopamine receptor activation differentially modulates rapidly inactivating and persistent sodium currents in prefrontal cortex pyramidal neurons. J Neurosci 21:2268-2277.
    • (2001) J Neurosci , vol.21 , pp. 2268-2277
    • Maurice, N.1    Tkatch, T.2    Meisler, M.3    Sprunger, L.K.4    Surmeier, D.J.5
  • 50
    • 0015182644 scopus 로고
    • Divalent ions and the surface potential of charged phospholipid membranes
    • McLaughlin SG, Szabo G, Eisenman G (1971) Divalent ions and the surface potential of charged phospholipid membranes. J Gen Physiol 58:667-687.
    • (1971) J Gen Physiol , vol.58 , pp. 667-687
    • McLaughlin, S.G.1    Szabo, G.2    Eisenman, G.3
  • 51
    • 20544443789 scopus 로고    scopus 로고
    • R-type calcium channels contribute to afterdepolarization and bursting in hippocampal CA1 pyramidal neurons
    • Metz AE, Jarsky T, Martina M, Spruston N (2005) R-type calcium channels contribute to afterdepolarization and bursting in hippocampal CA1 pyramidal neurons. J Neurosci 25:5763-5773.
    • (2005) J Neurosci , vol.25 , pp. 5763-5773
    • Metz, A.E.1    Jarsky, T.2    Martina, M.3    Spruston, N.4
  • 52
    • 0031917269 scopus 로고    scopus 로고
    • + current in rat neocortical pyramidal neurons
    • + current in rat neocortical pyramidal neurons. J Neurophysiol 79:1579-1582.
    • (1998) J Neurophysiol , vol.79 , pp. 1579-1582
    • Mittmann, T.1    Alzheimer, C.2
  • 53
    • 2342573680 scopus 로고    scopus 로고
    • Is the persistent sodium current a specific target of anti-absence drugs?
    • Niespodziany I, Klitgaard H, Georg Margineanu D (2004) Is the persistent sodium current a specific target of anti-absence drugs? NeuroReport 15:1049-1052.
    • (2004) NeuroReport , vol.15 , pp. 1049-1052
    • Niespodziany, I.1    Klitgaard, H.2    Georg Margineanu, D.3
  • 54
    • 0037207469 scopus 로고    scopus 로고
    • Molecular physiology of low-voltage-activated T-type calcium channels
    • Perez-Reyes E (2003) Molecular physiology of low-voltage-activated T-type calcium channels. Physiol Rev 83:117-161.
    • (2003) Physiol Rev , vol.83 , pp. 117-161
    • Perez-Reyes, E.1
  • 55
    • 0015803670 scopus 로고
    • Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. I. Behavioral correlates and firing repertoires
    • Ranck Jr JB (1973) Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. I. Behavioral correlates and firing repertoires. Exp Neurol 41:461-531.
    • (1973) Exp Neurol , vol.41 , pp. 461-531
    • Ranck Jr., J.B.1
  • 56
    • 0035310424 scopus 로고    scopus 로고
    • 2+-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy
    • 2+-dependent intrinsic bursting in the rat pilocarpine model of temporal lobe epilepsy. J Physiol (Lond) 532:205-216.
    • (2001) J Physiol (Lond) , vol.532 , pp. 205-216
    • Sanabria, E.R.1    Su, H.2    Yaari, Y.3
  • 57
    • 0016640871 scopus 로고
    • Characteristics of CA1 neurons recorded intracellularly in the hippocampal in vitro slice preparation
    • Schwartzkroin PA (1975) Characteristics of CA1 neurons recorded intracellularly in the hippocampal in vitro slice preparation. Brain Res 85:423-436.
    • (1975) Brain Res , vol.85 , pp. 423-436
    • Schwartzkroin, P.A.1
  • 58
    • 0030857906 scopus 로고    scopus 로고
    • Late sodium channel openings underlying epileptiform activity are preferentially diminished by the anticonvulsant phenytoin
    • Segal MM, Douglas AF (1997) Late sodium channel openings underlying epileptiform activity are preferentially diminished by the anticonvulsant phenytoin. J Neurophysiol 77:3021-3034.
    • (1997) J Neurophysiol , vol.77 , pp. 3021-3034
    • Segal, M.M.1    Douglas, A.F.2
  • 59
    • 0036793161 scopus 로고    scopus 로고
    • Molecular correlates of the M-current in cultured rat hippocampal neurons
    • Shah M, Mistry M, Marsh SJ, Brown DA, Delmas P (2002) Molecular correlates of the M-current in cultured rat hippocampal neurons. J Physiol (Lond) 544:29-37.
    • (2002) J Physiol (Lond) , vol.544 , pp. 29-37
    • Shah, M.1    Mistry, M.2    Marsh, S.J.3    Brown, D.A.4    Delmas, P.5
  • 62
    • 0034575581 scopus 로고    scopus 로고
    • Potassium-induced enhancement of persistent inward current in hippocampal neurons in isolation and in tissue slices
    • Somjen GG, Muller M (2000) Potassium-induced enhancement of persistent inward current in hippocampal neurons in isolation and in tissue slices. Brain Res 885:102-110.
    • (2000) Brain Res , vol.885 , pp. 102-110
    • Somjen, G.G.1    Muller, M.2
  • 64
    • 0028903712 scopus 로고
    • Activity-dependent action potential invasion and calcium influx into hippocampal CA1 dendrites
    • Spruston N, Schiller Y, Stuart G, Sakmann B (1995) Activity-dependent action potential invasion and calcium influx into hippocampal CA1 dendrites. Science 268:297-300.
    • (1995) Science , vol.268 , pp. 297-300
    • Spruston, N.1    Schiller, Y.2    Stuart, G.3    Sakmann, B.4
  • 65
    • 0033740752 scopus 로고    scopus 로고
    • Resting and active properties of pyramidal neurons in subiculum and CA1 of rat hippocampus
    • Staff NP, Jung HY, Thiagarajan T, Yao M, Spruston N (2000) Resting and active properties of pyramidal neurons in subiculum and CA1 of rat hippocampus. J Neurophysiol 84:2398-2408.
    • (2000) J Neurophysiol , vol.84 , pp. 2398-2408
    • Staff, N.P.1    Jung, H.Y.2    Thiagarajan, T.3    Yao, M.4    Spruston, N.5
  • 66
    • 0031239776 scopus 로고    scopus 로고
    • Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: Implications for neuroprotective strategies
    • Stefani A, Spadoni F, Bernardi G (1997) Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: implications for neuroprotective strategies. Exp Neurol 147:115-122.
    • (1997) Exp Neurol , vol.147 , pp. 115-122
    • Stefani, A.1    Spadoni, F.2    Bernardi, G.3
  • 67
    • 0023162293 scopus 로고
    • Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells
    • Storm JF (1987) Action potential repolarization and a fast after-hyperpolarization in rat hippocampal pyramidal cells. J Physiol (Lond) 385:733-759.
    • (1987) J Physiol (Lond) , vol.385 , pp. 733-759
    • Storm, J.F.1
  • 68
    • 0028867739 scopus 로고
    • Amplification of EPSPs by axosomatic sodium channels in neocortical pyramidal neurons
    • Stuart G, Sakmann B (1995) Amplification of EPSPs by axosomatic sodium channels in neocortical pyramidal neurons. Neuron 15:1065-1076.
    • (1995) Neuron , vol.15 , pp. 1065-1076
    • Stuart, G.1    Sakmann, B.2
  • 69
    • 0035876255 scopus 로고    scopus 로고
    • Extracellular calcium modulates persistent sodium current-dependent intrinsic bursting in rat hippocampal neurons
    • Su H, Alroy G, Kirson ED, Yaari Y (2001) Extracellular calcium modulates persistent sodium current-dependent intrinsic bursting in rat hippocampal neurons. J Neurosci 27:4173-4182.
    • (2001) J Neurosci , vol.27 , pp. 4173-4182
    • Su, H.1    Alroy, G.2    Kirson, E.D.3    Yaari, Y.4
  • 71
    • 0026094085 scopus 로고
    • The site for initiation of action potential discharge over the somatodendritic axis of rat hippocampal CA1 pyramidal neurons
    • Turner RW, Meyers DE, Richardson TL, Barker JL (1991) The site for initiation of action potential discharge over the somatodendritic axis of rat hippocampal CA1 pyramidal neurons. J Neurosci 11:2270-2280.
    • (1991) J Neurosci , vol.11 , pp. 2270-2280
    • Turner, R.W.1    Meyers, D.E.2    Richardson, T.L.3    Barker, J.L.4
  • 72
    • 0033787252 scopus 로고    scopus 로고
    • Riluzole inhibits the persistent sodium current in mammalian CNS neurons
    • Urbani A, Belluzzi O (2000) Riluzole inhibits the persistent sodium current in mammalian CNS neurons. Eur J Neurosci 12:3567-3574.
    • (2000) Eur J Neurosci , vol.12 , pp. 3567-3574
    • Urbani, A.1    Belluzzi, O.2
  • 74
    • 0019505714 scopus 로고
    • After potential generation in hippocampal pyramidal cells
    • Wong RK, Prince DA (1981) After potential generation in hippocampal pyramidal cells. J Neurophysiol 45:86-97.
    • (1981) J Neurophysiol , vol.45 , pp. 86-97
    • Wong, R.K.1    Prince, D.A.2
  • 76
    • 0028999445 scopus 로고
    • 2+ channel types by omega-conotoxin-MVIIC at hippocampal CA3 to CA1 synapses
    • 2+ channel types by omega-conotoxin-MVIIC at hippocampal CA3 to CA1 synapses. J Neurophysiol 73:1965-1972.
    • (1995) J Neurophysiol , vol.73 , pp. 1965-1972
    • Wu, L.G.1    Saggau, P.2
  • 77
    • 17644424970 scopus 로고    scopus 로고
    • Persistent sodium currents in mesencephalic v neurons participate in burst generation and control of membrane excitability
    • Wu N, Enomoto A, Tanaka S, Hsiao CF, Nykamp DQ, Izhikevich E, Chandler SH (2005) Persistent sodium currents in mesencephalic v neurons participate in burst generation and control of membrane excitability. J Neurophysiol 93:2710-2722.
    • (2005) J Neurophysiol , vol.93 , pp. 2710-2722
    • Wu, N.1    Enomoto, A.2    Tanaka, S.3    Hsiao, C.F.4    Nykamp, D.Q.5    Izhikevich, E.6    Chandler, S.H.7
  • 78
    • 0033227945 scopus 로고    scopus 로고
    • Characterization of riluzole-induced stimulation of large-conductance calcium-activated potassium channels in rat pituitary GH3 cells
    • Wu SN, Li HF (1999) Characterization of riluzole-induced stimulation of large-conductance calcium-activated potassium channels in rat pituitary GH3 cells. J Investig Med 47:484-495.
    • (1999) J Investig Med , vol.47 , pp. 484-495
    • Wu, S.N.1    Li, H.F.2
  • 79
    • 0023123383 scopus 로고
    • Development of two types of calcium channels in cultured mammalian hippocampal neurons
    • Yaari Y, Hamon B, Lux HD (1987) Development of two types of calcium channels in cultured mammalian hippocampal neurons. Science 235:680-682.
    • (1987) Science , vol.235 , pp. 680-682
    • Yaari, Y.1    Hamon, B.2    Lux, H.D.3
  • 80
    • 2442641611 scopus 로고    scopus 로고
    • KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons
    • Yue C, Yaari Y (2004) KCNQ/M channels control spike afterdepolarization and burst generation in hippocampal neurons. J Neurosci 24:4614-4624.
    • (2004) J Neurosci , vol.24 , pp. 4614-4624
    • Yue, C.1    Yaari, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.