Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells

Carcinogenesis

Volumn 26, Issue 10, 2005, Pages 1716-1730

  Lee, Jenq Chang ^a   Lee, Chao Hung ^b   Su, Chun Li ^c   Huang, Chung Wei ^a   Liu, Hsiao Sheng ^a   Lin, Chun Nan ^d   Won, Shen Jeu ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

^d KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 8; CASPASE 9; CYTOCHROME C; DNA FRAGMENT; JUSTICIA PROCUMBENS EXTRACT; JUSTICIDIN A; KU ANTIGEN; LIGNAN; PHOSPHATIDYLSERINE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; PROTEIN BAX; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER TRANSPLANTATION; CELL COUNT; CELL CYCLE G1 PHASE; COLORECTAL CANCER; CONTROLLED STUDY; CYTOPLASM; CYTOSOL; DRUG ISOLATION; DRUG PROTEIN BINDING; ENZYME ACTIVATION; ENZYME RELEASE; EXPOSURE; HUMAN; HUMAN CELL; JUSTICIA PROCUMBENS; MEDICINAL PLANT; MITOCHONDRION; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT;

EID: 27144458415     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgi133     Document Type: Article

References (40)

1. Pfister, D.G., Benson, A.B. III and Somerfield, M.R. (2004) Clinical Practice. Surveillance strategies after curative treatment of colorectal cancer. N. Engl. J. Med., 350, 2375-2382.
2. Mayer, R.J. (2004) Two steps forward in the treatment of colorectal cancer. N. Engl. J. Med., 350, 2406-2408.
3. Hawk, E.T., Umar, A. and Viner, J.L. (2004) Colorectal cancer chemoprevention - an overview of the science. Gastroenterology, 126, 1423-1447.
4. Kan, W.S. (1981) Pharmaceutical Botany. National Research Institute of Chinese Medicine, Taipei. Taiwan.
5. Hsu, H.Y. (1982) Treating, Cancer with Chinese Herbs. Oriental Healing Arts Institute, Los Angeles, USA.
6. Okigawa, M., Maeda, T. and Kawano, N. (1970) The isolation and structure of three new lignans from Justicia procumbens Linn var Leucantha Honda. Tetrahedron, 26, 4301-4305.
7. Fukamija, N. and Lee, K. (1986) Antitumor agents, justicidin-A and diphyllin, two cytotoxic principles from Justicia procumbens. J. Nat. Prod., 49, 349-350.
8. Day, S.H., Chiu, N.Y., Won, S.J. and Lin, C.N. (1999) Cytotoxic lignans of Justicia ciliata. J. Nat. Prod., 62, 1056-1058.
9. Day, S.H., Lin, Y.C., Tsai, M.L., Tsao, L.T., Ko, H.H., Chung, M.I., Lee, J.C., Wang, J.P., Won, S.J. and Lin, C.N. (2002) Potent cytotoxic lignans from Justicia procumbens and their effects on nitric oxide and tumor necrosis factor-alpha production in mouse macrophages. J. Nat. Prod., 65, 379-381.
10. Desagher, S. and Martinou, J.C. (2000) Mitochondria as the central control point of apoptosis. Trends Cell Biol., 10, 369-377.
11. Amarante-Mendes, G.P., Finucane, D.M., Martin, S.J., Cotter, T.G., Salvesen, G.S., and Green, D.R. (1998) Anti-apoptotic oncogenes prevent caspase-independent and independent commitment for cell death. Cell Death Differ., 57, 298-306.
12. Danial, N.N. and Korsimeyer, S.J. (2004) Cell death: Critical control points. Cell., 116, 205-219.
13. Adam, J.M. and Cory, S. (1998) The Bcl-2 protein family: Arbiters of cell survival. Science, 281, 1322-1326.
14. Evan, G. and Littlewood, T. (1998) A matter of life and cell death. Science, 281, 1317-1322.
15. Thornberry, N.A. and Lazebnik, Y. (1998) Caspases: Enemies within. Science, 281, 1312-1316.
16. Kluck, R.M., Bossy-Wetzel, E., Green, D.R. and Newmeyer, D.D. (1997) Ihe release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis. Science, 275, 1132-1136.
17. Shi, Y. (2001) A structural view of mitochondria-mediated apoptosis. Nat. Struct. Biol., 8, 394-401.
18. Bratton, S.B., Walker, G., Srinivasula, S.M., Sun, X.M., Butterworth, M., Alnemri, E.S. and Cohen, G.M. (2001) Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes. EMBO J., 20, 998-1009.
19. Nothwehr, S.F. and Martinou, J.C. (2003) A retention factor keeps death at bay. Nat. Cell Biol., 5, 281-283.
20. Cohen, H.Y. Lavu, S., Bitterman, K.J., Hekking, B., Imahiyerobo, T.A., Miller, C., Frye, R., Ploegh, H., Kessler, B.M. and Sinclair, D.A. (2004) Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Mol. Cell, 13, 627-638.
21. Stadler, J., Stefanovic-Racic, M., Billiar, T.R., Curran, R.D., McIntyre, L.A., Georgescu, H.I., Simmons, R.L., and Evans, C.H. (1991) Articular chondrocytes synthesize nitric oxide in response to cytokines and lipopolysaccharide. J. Immunol., 147, 3915-3920.
22. Chang, M.J., Yu, W.D., Reyno, L.M., Modzelewski, R.A., Egorin, M.J., Erkmen, K., Vlock, D.R., Furmanski, P. and Johnson, C.S. (1994) Potentiation by interleukin 1 alpha of cisplatin and carboplatin antitumor activity schedule-dependent and pharmacokinetic effects in the RIF-1 tumor model. Cancer Res., 54, 5380-5386.
23. Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J. Immunol. Methods, 65, 55-63.
24. Gamet-Payrastre, Li, P., Lumeau, S., Cassar, G., Dupont, M.A., Chevolleau, S., Gasc, N., Tulliez, J. and Terce, F. (2000) Sulforaphane. a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells. Cancer Res., 60, 1426-1433.
25. Lui, H.S., Scrable, H., Villaret, D.B., Lieberman, M.A. and Stambrook, P.J. (1992) Control of Haras-mediated mammalian cell transformation by Escherichia coli regulatory elements. Cancer Res., 52, 983-989.
26. Chang, M.Y., Won, S.J., Yang, B.C., Jan, M.S. and Liu, H.S. (1999) Selective activation of Ha-ras(val12) oncogene increases susceptibility of NIH/3T3 cells to TNF-alpha. Exp. Cell Res., 248, 589-598.
27. Perkins, C.L., Fang, G., Kim, C.N. and Bhalla, K.N. (2000) The role of Apaf-1, caspase-9 and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis. Cancer Res., 60, 1645-1653.
28. Troiano, L., Granata, A.R., Cossarizza, A., Kalashnikova, G., Bianchi, R., Pini, G., Tropea, F., Carani, C. and Franceschi, C. (1998) Mitochondrial membrane potential and DNA stainability in human sperm cells: A flow cytometry analysis with implications for male infertility. Exp. Cell Res., 241, 384-393.
29. Mathur, A., Hong, Y., Kemp, B.K., Barrientos, A.A. and Erusalimsky, J.D. (2000) Evaluation of fluorescent dyes for the detection of mitochondrial membrane potential changes in cultured cardiomyocytes. Cardiovasc. Res., 46, 126-138.
30. Yang, J., Liu, X., Bhalla, K., Kim, C.N., Ibrado, A.M., Cai, J., Peng, T.I., Jones, D.P. and Wang, X. (1997) Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science, 275, 1129-1132.
31. Nadakavukaren, K.K., Nadakavukaren, J.J. and Chen, L.B. (1985) Increased rhodamine 123 uptake by carcinoma cells. Cancer Res., 45, 6093-6099.
32. Watabe, M., Machida, K. and Osada, H. (2000) MT-21 is a synthetic apoptosis inducer that directly induces cytochrome c release from mitochondria. Cancer Res., 60, 5214-5222.
33. Earnshaw, W.C., Martin, L.M. and Kaufmann, S.H. (1999) Mammalian caspases: Structure, activation, substrates, and functions during apoptosis. Annu. Rev. Biochem., 68, 383-424.
34. Tseng, Y.S., Tzeng, C.C., Chiu, A.W., Lin, C.H., Won, S.J., Wu, I.C. and Liu, H.S. (2003) Ha-ras overexpression mediated cell apoptosis in the presence of 5-fluorouracil. Exp. Cell Res., 288, 403-414.
35. Enari, M., Sakahira, H., Yokoyama, H., Okawa, K., Iwamatsu, A. and Nagata, S. (1998) A caspase-activated/DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature, 391, 43-50.
36. Jayanthi, S., Deng, X., Noailles, P.A., Ladenheim, B. and Cadet, J.L. (2004) Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades. FASEB J., 18, 238-251.
37. Kumar, S. and Vaux, D.L. (2002) Apoptosis. A cinderella caspase takes center stage. Science, 297, 1290-1291.
38. Sawada, M., Sun, W., Hayes, P., Leskov, K., Boothman, D.A. and Matsuyama, S. (2003) Ku70 suppresses the apoptotic translocation of Bax to mitochondria. Nat. Cell Biol., 5, 320-329.
39. Tsao, L.T., Lin, C.N. and Wang, J.P. (2004) Justicidin A inhibits the transport of tumor necrosis factor-alpha to cell surface in lipopolysaccharide-stimulated RAW 264.7 macrophages. Mol. Pharmacol., 65, 1063-1069.
40. Asano, J., Chiba, K., Tada, M. and Yoshii, T. (1996) Antiviral activity of lignans and their glycosides from Justicia procumbens. Phytochemistry, 42, 713-717.